Drugs of Ophthalmology

Donald S.
Fong
Simon K. Law
Ursula Schmidt-Erfurth
Editors
Drugs in Ophthalmology
Donald S. Fong
Simon K. Law
Ursula Schmidt-Erfurth
Editors
Drugs in
Ophthalmology
13
Donald S. Fong, MD, MPH Ursula Schmidt-Erfurth, MD
Director Professor and Chair
Clinical Trials Department of Ophthalmology
Department of Research and Evaluation Medical University of Vienna
Kaiser Permanente Southern California Währinger Gürtel 18–20
100 S. Los Robles A-1090 Vienna, Austria
Pasadena
CA 91101, USA
Simon K. Law, MD, PharmD

Jules Stein Eye Institute
100 Stein Plaza 2-235
Los Angeles
CA 90095, USA
ISBN-10 3-540-23435-7 Springer-Verlag Berlin Heidelberg New York

ISBN-13 978-3-540-23435-7 Springer-Verlag Berlin Heidelberg New York
Library of Congress Control Number: 2005933261
This work is subject to copyright. All rights are reserved, whether the whole or part of the
material is concerned, specifically the rights of translation, reprinting, reuse of illustrations,
recitation, broadcasting, reproduction on microfilm or in any other way, and storage in data
banks. Duplication of this publication or parts thereof is permitted only under the provisions
of the German Copyright Law of September 9, 1965, in its current version, and permission
for use must always be obtained from Springer. Violations are liable to prosecution under
the German Copyright Law.
Springer is a part of Springer Science+Business Media

springeronline.com
© Springer-Verlag Berlin Heidelberg 2006
Printed in Germany
The use of general descriptive names, registered names, trademarks, etc. in this publication
does not imply, even in the absence of a specific statement, that such names are exempt from
the relevant protective laws and regulations and therefore free for general use.
Product liability: the publishers cannot guarantee the accuracy of any information about
dosage and application contained in this book. In every individual case the user must check
such information by consulting the relevant literature.
Editor: Marion Philipp, Heidelberg, Germany

Desk Editor: Martina Himberger, Heidelberg, Germany
Production: ProEdit GmbH, Heidelberg, Germany
Cover: Frido Steinen-Broo, EStudio Calamar, Spain
Typesetting: Stürtz GmbH, Würzburg, Germany
Printed on acid-free paper 24/3151 Re 5 4 3 2 1 0

Disclaimer
The nature of drug information is that it is constantly changing because of continu-
ing research and clinical experience and is often subject to ongoing evaluation. While
significant care has been taken to ensure the accuracy of the information, the reader
is advised that the authors, editors, reviewers, contributors, and publishers cannot be
responsible for the continued currency of the information, for any errors or omissions in
this book, or for any consequences arising therefrom. Because of the changing nature
of drug information, readers are advised that decisions regarding drug therapy must
be based on the independent judgment of the ophthalmologist, changing information
(literature and manufacturer‘s information), and changing medical practice.
List of Contributors
Amani A. Fawzi, MD
University of Southern California
Keck School of Medicine
Doheny Eye Institute
San Pablo Street 1450
Los Angeles
CA 90033, USA
Donald S. Fong, MD, MPH

Director
Clinical Trials
Department of Research and Evaluation
Kaiser Permanente Southern California
100 S. Los Robles
Pasadena
CA 91101, USA
Simon K. Law, MD, PharmD

Jules Stein Eye Institute
100 Stein Plaza 2-235
Los Angeles
CA 90095, USA
Rike Michels
Department of Ophthalmology
Medical University of Vienna
Währinger Gürtel 18–20
A-1090 Vienna, Austria
Ursula Schmidt-Erfurth, MD
Professor and Chair
Department of Ophthalmology
Medical University of Vienna
Währinger Gürtel 18–20
A-1090 Vienna, Austria
Hasan Syed, MD, Stanford University

Medical Center
General Surgery
Welch Road 1170
Palo Alto
CA 94304, USA
Table of Contents
I Alphabetical Listing of Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1
II Dosage Summary for Anti-infectives . . . . . . . . . . . . . . . . . . . . . . . . . . . 221

Introduction
This drug handbook is divided into two sections:
Alphabetical Listing of Drugs

Entries in this section are listed by generic name. Information for each drug is arranged
in a consistent format for easy reference. If one or more of the following categories is not
applicable to a certain drug, it will not be listed. If Pregnancy Category is not listed for an
individual drug, then it is either listed under the first drug in a group of drugs, or safety
and efficacy in pregnancy have not been established.
Summary of Anti-infectives
This section summarizes the common doses of antibiotics, antifungals, and antivirals.
For each drug, the dose for each route of administration is included.
Generic name
Brand names Common trade names
Class of drug Therapeutic class
Indications Common uses of the drug
Dosage form Common forms of the drug
Dose The amount of drug to be given or taken during therapy.

The dosage is to be taken as a guideline and does not
preclude other dosage regimens
Contraindications Information pertaining to inappropriate use of the drug
Warnings Hazardous conditions related to use of the drug and disease

states or patient populations in which the drug should be
used cautiously
Adverse reactions Considerations to be taken into account
Pregnancy category FDA categories that indicate the potential for causing birth
defects
Controlled studies in pregnant women have failed to
A demonstrate a risk to the fetus in the first trimester with no
evidence of risk in later trimesters. The possibility of fetal
harm appears remote
Either animal-reproduction studies have not demonstrated
B a fetal risk but there are no controlled studies in pregnant
women, or animal-reproduction studies have shown an
adverse effect that was not confirmed in controlled studies
in women in the first trimester and there was no evidence
of a risk in later trimesters
Either studies in animals have revealed adverse effects on the
C fetus (teratogenic, embryocidal effects, or other) and there
are no controlled studies in women, or studies in women and
animals are not available. Drugs should be given only if the
potential benefits justify the potential risk to the fetus
There is positive evidence of human fetal risk, but the
D benefits from use in pregnant women may be acceptable
despite the risk (e.g., if the drug is needed in a life-threate-
ning situation or for a serious disease for which safer drugs
cannot be used or are ineffective)
6
Generic name
X Studies in animals or humans have demonstrated fetal

abnormalities or there is evidence of fetal risk based on
human experience, or both, and the risk of the use of the
drug in pregnant women clearly outweighs any possible
benefit. The drug is contraindicated in women who are or
may become pregnant
Drug interactions Only clinically important interactions are listed

Drugs of Ophthalmology

Uploaded by

Copyright:

Available Formats

Drugs of Ophthalmology

Uploaded by

Document Information

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Drugs of Ophthalmology

Uploaded by

Copyright:

Available Formats

Donald S.

Simon K. Law, MD, PharmD

ISBN-10 3-540-23435-7 Springer-Verlag Berlin Heidelberg New York

Library of Congress Control Number: 2005933261

Springer is a part of Springer Science+Business Media

Editor: Marion Philipp, Heidelberg, Germany

Printed on acid-free paper 24/3151 Re 5 4 3 2 1 0

Donald S. Fong, MD, MPH

Simon K. Law, MD, PharmD

Hasan Syed, MD, Stanford University

II Dosage Summary for Anti-infectives . . . . . . . . . . . . . . . . . . . . . . . . . . . 221

Alphabetical Listing of Drugs

Brand names Common trade names

Class of drug Therapeutic class

Indications Common uses of the drug

Dosage form Common forms of the drug

Dose The amount of drug to be given or taken during therapy.

Contraindications Information pertaining to inappropriate use of the drug

Warnings Hazardous conditions related to use of the drug and disease

Adverse reactions Considerations to be taken into account

X Studies in animals or humans have demonstrated fetal

Drug interactions Only clinically important interactions are listed

You might also like