This PDF Is The Sample PDF Taken From Our Comprehensive Study Material For NEET & Aiims
This PDF Is The Sample PDF Taken From Our Comprehensive Study Material For NEET & Aiims
This PDF Is The Sample PDF Taken From Our Comprehensive Study Material For NEET & Aiims
INTRODUCTION
W
hen you look around, you see the diversity of living world comprising of various
organisms like microscopic bacteria to huge multicellular plants and animals. You
must have also wondered and asked yourself several times - “What is it that makes
an organism living, or what is it that an inanimate thing does not have which a living
thing has?” The answer to this is the presence of the basic unit of life--the cell in all
living organisms.
All living organisms possess life and are made up of basic unit structure called Cell.
An organisms consists of one or more cells. Accordingly there are of two types of
organisms:
(i) Unicellular organisms-e.g. Amoeba, Diatoms etc. (ii) Multicellular organisms e.g.
Plants,Animals etc.
BIOLOGY FOR NEET & AIIMS
What is Cytology?
Cytology : Structural study of cell
What is Cell Biology?
Cell Biology : Structural & Functional study of cell.
HISTORY
Discovery of cell – In 1665 Robert Hooke examined thin slices of cork under his self made microscope
(Magnification = 42 times). The cork seen was dead bark of spanish oak (Quercus suber). Robert
Hook coined the term "Cellula" for Honey comb like structure of bottle cork (Greek cellulae = Hollow
space) which later modified to cell. Actually he saw only the dead cell walls of plant cells. He
published his findings in his book 'Micrographia'.
Karl Nageli showed that cells in plants arises by the division of pre existing cell.
Discovery of living cell by Leeuwenhoek–
Leeuwenhoek examined mud, semen, saliva, blood, Insects etc. Under his self made microscope and
observe protozoans, sperm, bacteria, RBC, muscle cells etc.
He called these tiny creatures as "Animalcules" and published his finding in "Secrets of nature”.
He is known as father of microbiology, father of bacteriology, father of protozoology.
R.Virchow stated "Omnis cellula e cellula" which means all cells arises from pre existing cell. This is known
as "Law of Lineage".
Father of cytology is Hertwig & R. Hooke.
Father of Indian cytology is Dr. A.K. Sharma.
Father of modern cytology is C.P. Swannson.
General facts Related With cells
Longest cell is nerve cell of Giraffe. (more than 1m) (90 cm in man).
Largest cell is egg of ostrich (17cm x 13.5 cm dimension).
Smallest cell is PPLO (Pleuro Pneumonia Like Organism).
Smallest plant cell mycoplasma Laidlawii 0.1 .
Largest plant cell – Acetabularia (10cm)
Longest plant cell – Remie fibre (Boehmeria nevia)
Centre for cellular and molecular biology is at Hyderabad.
Cell Theory
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Apposition
Intussusception
When the particles are deposited between the substance which are already present then this types of growth
is called Intussusception Growth
This types of growth takes place in primary, secondary and tertiary cell wall.
Apposition (Accretion)
When the layers are desposited on to the layers which are present already , then this types of growth is
called apposition growth
This types of growth takes place in secondary cell wall.
Functions
Cell wall protects the protoplasm.
Cell wall gives a particular size & shape to cell & functions in form of exoskeleton of cell.
It gives a mechanical support to cell.
Cell wall is permeable so it helps in transport of water & mineral substances
Cell wall plays an important role in absorption, transpiration, transport and secretion etc.
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PLASMA MEMBRANE
Term plasma lemma was given by J.Q. Plower (1885).
Term cell membrane or plasma membrane was given by Nagelli.
Term unit membrane was given by Robertson.
At first, structure of cell membrane was studied by Overton and postulated that cell membrane is composed
of a continous layer of lipid material.
It is outermost boundary of animal cell.
Oligosaccharide
Integral protein
Glycolipid
Hydrophobic -halix
Cholesterol Phospholipid
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The cell is the basic structural, functional and biological unit of all known living organisms,
Robert Hooke (1665) observedd honey-comb like dead cells in a thin slice of cork and named them ‘cell’. Anton van
Leeuwenhoek (1667) was the first to describe a living cell.
The properties of a living organism depend on those of its individual and RNA found in the cell nucleus and
cytoplasm.
All cells are basically the same in chemical composition in organisms of similar species. Energy flow (metabolism
and biochemistry) occurs within cells.)
Plasma Membrane
Plasmalemma contains about 58 - 59 % proteins, 40 % lipids and 1-2 % carbohydrates.
Autosomes: These are the somatic chromosomes which do not take part in fertilisation process. These are also
called allosomes and they are 44 in number in human body.
MITOCHONDRIA
Visible under the microscope only after specific staining.
Number per cell is variable, depending on the physiological activity of the cells.
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SOLVED EXAMPLE
Ex.1 Who invented the "electron microscope" Sol. (A) : M. J. Schledin and T. Schwann (1838 - 39)
proposed cell theory
(A) Knoll and Ruska
(B) Robert Brown Ex.6 Which of the following is absent in prokaryotes
(C) Correns (A) Nuclear membrane
(B) Golgi bodies
(D) Janssen and Janssen
(C) Endoplasmic reticulum
Sol. (A) (D) All the above
Sol. (D)
Ex.2 With the increase in diameter of the rotor, the
effective RCF (relative centrifugal force) at a fixed Ex.7 Middle lamella is made up of
RPM (revolutions per minute) will (A) Cellulose
(B) Suberin
(A) Remain unaffected
(C) Calcium and magnesium pectate
(B) Increase (D) Lignin
(C) Decrease Sol. (C)
(D) Be lower at the bottom of centrifugal tube
Ex.8 Plant cell wall consists of
Sol. (B)
(A) Lignin + hemicellulose + pectin + lipid
(B) Lignin + protein + hemicellulose + pectin
Ex.3 Detailed structure of the membrane was studies after
(C) Lignin + hemicellulose + pectin + cellulose
the advent of electron microscope during
(D) Lignin + hemicellulose + tubulin+ lipid
(A) 1930 's (B) 1950 's Sol. (C)
(C) 1970 's (D) 1990 's
Ex.9 Cell wall is absent in
Sol. (B)
(A) Gametes (B) Amoeba
(C) Mycoplasma (D) All of these
Ex.4 Which of the following is used for observing spindle
Sol. (D)
fibres
Or Ex.10 The type of cell junction which facilitates cell to cell
communication is
The microscope usually used for seeing living cells
(A)Tight junction (B) Adhering junction
or tissues
(C) Gap junction (D) Desmosomes
(A) Dark field microscope (E) Brush borders
(B) Phase contrast microscope Sol. (C)
(C) Polarisation microscope
Ex.11 According to widely accepted "Fluid mosaic model"
(D) Scanning transmission electron microscope cell membranes are semi-fluid, where lipids and
integral proteins can diffuse randomly. In recent
Sol. (B) : Phase contrast microscope is used to observe years, this model has been modified in several
living cells and cell organs i.e., spindle fibres, respects. In this regards, which of the following
pinocytosis, karyokinesis, cytokinesis etc. statements is incorrect
(A) Proteins in cell membranes can travel within the
Ex.5 Who proposed the "Cell theory" lipid bilayer
(B) Proteins can also undergo flip-flop movements
(A) Schleiden (botanist) and Schwann (zoologist)
in the lipid bilayer.
(B) Waston and Crick (C) proteins can remain confined within certain
(C) Mendel and Morgan domains of the membrane
(D) Many proteins remain completely embedded
(D) Robert Hooke within the lipid bilayer
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1. Which of the following is the smallest cell- 10. Small particles present on inner mitochondrial
(A) Human nerve cells (B) Chlamydomonas membrane are called-
(C) Virus (D) PPLO (A) Cristae (B) Ergatosomes
(C) Elementary particles (D) Quantasome
2. Which of the following is true of the carbohy-
drate portion of the cell membrane-
11. Lysosomes are called "suicide bags" because
(A) It contributes to the polycationic charge on they have-
the extracellular surface
(A) Catabolic enzymes (B) Food vacuole
(B) It is 1% of plasma membrane
(C) It is found primarily in the form of free sac- (C) Hydrolytic enzymes (D) Parasitic activity
charide groups
12. In which of the following cells the endoplasmic
(D) It has a symmetric distributions
reticulum is absent-
3. Plasmalemma of animal cells is elastic due to the (A) Kidney cells
presence of-
(B) Liver cells
(A) Proteins (B) Lipids
(C) Mammalian mature erythrocytes
(C) Carbohydrates (D) Microfilaments
(D) Mammalian eye cells
4. The most abundant substance of middle lamella is-
(A) Lignin (B) Suberin 13. If cells are broken up and sedimented by centrifu-
(C) Pectin (D) Cutin gation, the new structures formed in one of the
fraction is-
5. Cell wall is the secretory product of- (A) Centrosomes (B) Microsomes
(A) Lysosomes (B) Cytoplasm
(C) Peroxisomes (D) Lysosomes
(C) Plasmodesmata (D) Middle lamella
14. The endoskeleton of the cell is made up of-
6. The size of the nucleolus is large where-
(A) Cell wall (B) Cytoplasm
(A) Protein synthesis is active
(C) E.R. (D) Mitochondria
(B) Protein synthesis is less
(C) No protein synthesis occurs 15. Match the following
(D) None of the above (A) Microtubules - Structural component of cilia
7. Aerobic respiration is performed by- (B) Centrioles - Store hydrolases
(A) Iysosomes (B) Chloroplast (C) Peroxisomes - Stores carbohydrate, fats and
proteins in plants
(C) Mitochondria (D) Glyoxysomes
(A) 1 correct, 2 and 3 false
8. Mitochondria are most abundant in- (B) 1 and 3 correct, 2 false
(A) Heart muscle (B) Muscles of thigh (C) 1 and 2 correct, 3 false
(C) Wings of birds (D) None (D) All are false
9. Cytochrome oxidases are found-
16. The carbohydrates which project out of the lipid
(A) On outer wall of mitochondria bilayer in animal cell membrane are linked to -
(B) In the matrix of mitochondria (A) Lipids only (B) Proteins only
(C) In the lysosomes
(C) Peptidoglycan (D) Both lipid & protein
(D) On cristae of mitochondria
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1. Butter Sandwich model of plasma membrane was 8. Which cell organelle secretes zymogen granules
proposed by - (A) Lysosomes (B) Golgibody
(A) Davson and Danielli (C) Smooth E.R. (D) Sphaerosomes
(B) Robertson
9. Mitochondrial DNA is -
(C) Singer and Nicolson
(A) Naked (B) Circular
(D) Benson
(C) Double stranded (D) All the above
2. Ingestion of solid food by plasma membranes is 10. Lysosomes are not helpful in -
called -
(A) Osteogenesis
(A) Endosmosis (B) Pinocytosis
(B) Cellular digestion
(C) Cytokinesis (D) Phagocytosis (C) Metamorphosis in frog
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1. Match Column-I with Column-II and select the correct option from the codes given below
Column - I Column - II
A. Leeuwenhoek i. First saw and described a living cell
B. Robert Brown ii. Presence of cell wall is unique to plant cells
C. Schleiden iii. Discovered the nucleus
D. Schwann iv. All plants are composed of different kind of cells
(A) A-i, B-iii, C-iv, D-ii (B) A-i, B-iii, C-ii, D-iv
(C) A-iii, B-i, C-iv, D-ii (D) A-i, B-iv, C-ii, D-iii
3. Match Column-I with Column-II and select the correct option from the codes given below.
Column - I Column - II
A. Mitochondria i. Without membrane
B. Lysosomes ii. Single membrane
C. Ribosomes iii. Double membrane
D. Nucleus
A B C D
(A) i ii iii iii
(B) iii i i ii
(C) iii ii i iii
(D) ii iii i iii
4. Match Column - I with Column - II and select the correct option from the codes given below.
Column - I Column - II
A. Dictyosomes i. Storage
B. Mitochondria ii. Photosynthesis
C. Vacuoles iii. Transport
D. Grana iv. Secretion
v Respiration
A B C D
(A) iv v i ii
(B) i ii iv iii
(C) iv i ii iii
(D) i ii iii iv
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1. The cell organelle involved in glycosylation of pro- 9. A student wishes to study the cell structure under a
tein [CBSE AIPMT-2000] light microscope cell structure under a light micro-
(A) ribosome (B) peroxisome scope having 10X eyepiece and 45X objective. he
(C) endoplasmic (D) mitochondria should ikkuminate the object by which one of the
following colurs of light so as to get the bestpossible
2. Lysosomes are reservoirs of [CBSE AIPMT-2000] resolution ? [CBSE AIPMT-2004]
(A) RNA and protein (A) Blue (B) Green
(B) fats (C) Yellow (D) Red
(C) secretory glycoproteins
10. Chlorophyll in chloroplast is located in
(D) hydrolytic enzymes [CBSE AIPMT-2005]
3. Microtubules are absent in[CBSE AIPMT-2001] (A) grana (B) pyrenoid
(C) stroma (D) Both (A) and (C)
(A) mitochondria (B) centriole
(C) flagella (D) spindle fibres
11. Protein synthesis in an animal cell occurs
4. In ‘fluid mosaic model of plasm [CBSE AIPMT-2000,05]
[CBSE AIPMT-2002] (A) only on the ribosomes present in cytosol
(A) upper layer is non-polar and hydrophilic (B) only on ribosomes attached to the nuclear en-
(B) upper layer is polar and hydrophobic velope and endoplasmic reticulum
(C) phospholipids form a bimolecular layer in middle (C) on ribosomes present in the nucleolus as well as
part in cytoplasm
(D) proteins form a middle layer (D) on ribosomes present in cytoplasm as well as in
mitochondria
5. Ribosomes are produced in [CBSE AIPMT-2002] 12. According to widely accepted ‘fluid mosaic model’,
(A) nucleolus (B) cytoplasm cell membranes are semifluid, where lipids and interal
(C) mitochondria (D) golgi body proteins can diffuse randomly. In recent years, this
model has benn modified in several respects. In this
6. Flagella of prokaryotic and eukaryotic cells differ in regard, which of the following statements in incor-
[CBSE AIPMT-2004]
rect? [CBSE AIPMT-2005]
(A) type of movement and placement in cell
(A) Proteins in cell membranes can travel within the
(B) location in cell and mode of funcitioning lipid bilayer
(C) microtubular organisation and type of move- (B) Proteins can also undergo flip-flop movements
ment in the lipid bilayer
(D) microtubular organisation and function (C) Proteins can remain confined within certain do-
mains of the membrane
7. Inchloroplasts, chlorophyll is present in the
[CBSE AIPMT-2004] (D) many proteins remain completely embedded
(A) outer membrane (B) inner membrane within the lipid bilayer
(C) thylakoids (D) stroma
13. The main organelle involved in modification and
8. Extra nuclear inheritance is a consequence of pres- routing of newly synthesised proteins to their des-
ence of genes in [CBSE AIPMT-2004] tinations is [CBSE AIPMT-2005]
(A) mitochondria and chloroplasts (A) chloroplast
(B) endoplasmic reticulum and mitochondria (B) mitochondria
(C) ribosomes and chloroplast (C) lysosome
(D) lysosomes and ribosomes (D) endoplasmic reticulum
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MOCK TEST
1. A nanometre is
(A) 10–9 m (B) 10–4 m (C) 10–6 m (D) 10–12 m
(E) 109 m
2. Objects less than 0.2 m in size cannot be seen under light microscope because
(A) the wavelength of visible light is 3900 Å to 7800 Å
(B) only two types of lenses are used
(C) maximum magnifying power of ocular lens is 20 X
(D) maximum magnifying power of objective lens is 100 X.
6. Cells divide and new cells are formed from pre-existing cells. This concept was given by
(A) Matthias Schleiden
(B) Theodore Schwann
(C) Matthias Schleiden and Theodore Schwann
(D) Rudolf Virchow
7. Assertion : Pili are tubular structures present in bacteria which help in conjugation.
Reason : Formation of pili is controlled by F+ or fertility factor.
(A) If both assertion and reason are true and reason is the correct explanation of assertion.
(B) If both assertion and reason are true but reason is not the correct explanation of assertion.
(C) If assertion is true but reason is false.
(D) If both assertion and reason are false.
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11th Class Modules Chapter Details