DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ NURSING

OF ACTION ADVERSE RESPONSIBILITIES

REACTIONS
Generic Name After Prophylaxis for  Hypersensitivity  Pseudomembranous  Instruct patient to
Sultamicillin absorption, breast cancer colitis immediately report
tosylate sultamicillin surgery on the  Anaphylactic shock signs and
releases prevention of  Dizziness symptoms of
Brand Name ampicillin and surgical site  Somnolence hypersensitivity
Zunamyn sulbactam into infection  Sedation reaction, such as
the system.  Headache rash, fever, or
Classifications Ampicillin  Dyspnea chills.
Penicillin exerts  GI disorders  Advise patient to
antibacterial minimize GI upset
Dose activity against by eating small,
750 mg/tab; sensitive frequent servings
one tablet organisms by of food and
twice a day inhibiting drinking plenty of
biosynthesis of fluids.
Route cell wall  Inform patient that
Oral mucopeptide drug lowers
whereas resistance to
sulbactam certain infections.
irreversibly Tell patient to
inhibits most promptly report
important beta- unusual bleeding or
lactamases that bruising.
occur in
resistant strains.
 DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ ADVERSE NURSING
OF ACTION REACTIONS RESPONSIBILITIES
Generic Name It is a non- Postoperative  History of asthma  CNS: Trouble in sleeping,  Lab tests: Monitor
Dexketoprofen steroidal anti- pain attack, bronchospasm, nervousness, headache, baseline and
trometamol inflammatory acute rhinitis/nasal dizziness; depression, periodic
drug (NSAID) polyp drowsiness, confusion, evaluations of
that reduces  Urticaria/angioneurotic migraine, vertigo. hemoglobin, renal
Classifications prostaglandin edema  CV: Peripheral edema, and hepatic
Non-steroidal synthesis via  Gastric ulcer/chronic palpitations, hypertension, function.
anti- inhibition of dyspepsia, gastric tachycardia.  Monitor for S&S of
inflammatory cyclooxygenase bleeding, Crohn’s  Special Senses: Visual GI ulceration (e.g.,
drug pathway (both disease/ulcerative disturbances; Dry nose or stool for occult
COX-1 and colitis throat, tinnitus, hearing blood, persistent
Dose COX-2)  Severe cardiac failure impairment. indigestion).
One tablet activity  Moderate to severe  GI: Dyspepsia, nausea,  Report promptly
every 8 hours renal dysfunction vomiting, diarrhea, signs of jaundice as
 Severe liver constipation, flatulence, well as the
Route dysfunction stomach pain, anorexia, dry following: blurred
Oral hemorrhagic diathesis mouth. vision, tinnitus,
 Coagulation disorders  Skin: Rash, pruritus, urinary urgency or
 Anticoagulant therapy urticaria, erythema, frequency,
photosensitivity. unexplained
bleeding, weight
gain with edema.
 Note: Possible
CNS adverse
effects (e.g., light-
headedness,
dizziness,
drowsiness).
 DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE EFFECTS/ NURSING
OF ACTION ADVERSE RESPONSIBILITIES
REACTIONS
Generic Name Inhibits cell- Perioperative  Hypersensitivity  Hypersensitivity  Monitor patient for
Cefuroxime wall synthesis, prophylaxis reactions signs and
sodium promoting  Diarrhea, nausea, symptoms of
osmotic pseudomembranous superinfection and
Classifications instability; colitis diarrhea.
Second- usually  Decreased Hb  Instruct patient to
generation bactericidal. concentration &/or notify prescriber
cephalosporins eosinophilia, about rash, loose
leucopenia, & stools, diarrhea, or
Dose neutropenia may evidence of
 1.5 g thru occur superinfection
IV 1 hour  Transient rise in  Advise patient
prior to OR SGOT & SGPT, & receiving drug I.V.
ANST bilirubin to report
 750 mg discomfort at I.V.
TIV q8 insertion site.

Route
IV
 DRUG MECHANISM INDICATIONS CONTRAINDICATIONS SIDE NURSING
OF ACTION EFFECTS/ RESPONSIBILITIES
ADVERSE
REACTIONS
Generic Name Reduces gastric Prophylactic  Hypersensitivity  CNS:  Monitor patient for
Esomeprazole acid secretion agent for acid headache, rash or signs and
and decreases aspiration dizziness symptoms of
Classifications gastric activity.  GI: hypersensitivity.
Proton Pump abdominal  Instruct patient to
Inhibitors pain, alert prescriber if
constipation, rash or other signs
Dose diarrhea, dry and symptoms of
40 mg tablet 30 mouth, allergy occur.
minutes prior flatulence,
NPO nausea,
vomiting
Route  Skin:
Oral pruritus