(Concept Map) Urinary Tract Infections

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Floating Topic

History, signs and symptoms

urine dipstick test can confirm the diagnosis of


uncomplicated
cystitis (nitrite or leukocyte esterase positivity)
Urine Dipstick Test,
Urine culture: diagnostic “GOLD STANDARD” for UTI Urinalysis, and Urine
Diagnostics
Culture
colony count threshold of >100 bacteria/mL in women
Most commonly in females (between 1-50 yo)
colony count threshold of >1000 bacteria/mL in men
neonatal period = slightly higher among
Meares-Stamey 4-glass test: for chronic bacterial prostatitis Other Epidemiology males (higher incidence of congenital
urinary tract anomalies)

after age 50 = obstruction from BPH


does not have local or systemic symptoms common in men
referable to the urinary tract Asymptomatic Bacteriuria

dysuria, urinary frequency, urgency; nocturia, hesitancy,


in acute cystitis: sexual activity, recent use
suprapubic discomfort, and gross hematuria Cystitis
of a diaphragm with spermicide
3
- MILD: low-grade fever with or without CVA pain,
- SEVERE: high fever ("picket-fence" pattern), rigors,
Urinary Tract frequent sexual
intercourse; history of
in pyelonephritis: new sexual partner
Risk Factors UTI in the previous 12 months
nausea, vomiting, and flank and/or loin pain Pyelonephritis
Clinical Presentation Infections UTI; incontinence, DM

- ACUTE: dysuria, frequency, and pain in the prostatic pelvic in recurrent UTI: use of spermicide, new
or perineal area + fever and chills sexual partner, first UTI before 15 years of
- CHRONIC: more insidious; recurrent episodes of cystitis + age
pelvic and perineal pain Prostatitis

anatomic predisposition to infection, with a foreign


E. coli (75–90% ); S. saprophyticus (5–15%) Klebsiella, Proteus,
body in the urinary tract, or with factors predisposing Etiology Enterococcus, and Citrobacter (5–10%)
to a delayed response to therapy Complicated UTI

ascending from the urethra


Routes of bacterial entry
hematogenous spread: <2% into the urinary tract
Pathogenicity

foreign body (catheter or stone)

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