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    Metronidazole

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    hauteanicole
    Metronidazole is an antibiotic and antiprotozoal drug used to treat various anaerobic bacterial infections and parasitic infections. It works by disrupting the DNA of anaerobic bacteria and protozoa. Common brand names include Flagyl. It is available in both oral and topical formulations. Metronidazole is indicated to treat conditions like bacterial vaginosis, rosacea, and trichomoniasis. Common side effects include nausea, vomiting, and metallic taste. Nursing responsibilities include monitoring for drug interactions and side effects.

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    Metronidazole

    Uploaded by

    hauteanicole
    382 views2 pages
    Metronidazole is an antibiotic and antiprotozoal drug used to treat various anaerobic bacterial infections and parasitic infections. It works by disrupting the DNA of anaerobic bacteria and protozoa. Common brand names include Flagyl. It is available in both oral and topical formulations. Metronidazole is indicated to treat conditions like bacterial vaginosis, rosacea, and trichomoniasis. Common side effects include nausea, vomiting, and metallic taste. Nursing responsibilities include monitoring for drug interactions and side effects.

    Original Description:

    Drug Study: Metronidazole

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    Metronidazole is an antibiotic and antiprotozoal drug used to treat various anaerobic bacterial infections and parasitic infections. It works by disrupting the DNA of anaerobic bacteria and protozoa. Common brand names include Flagyl. It is available in both oral and topical formulations. Metronidazole is indicated to treat conditions like bacterial vaginosis, rosacea, and trichomoniasis. Common side effects include nausea, vomiting, and metallic taste. Nursing responsibilities include monitoring for drug interactions and side effects.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    382 views2 pages

    Metronidazole

    Uploaded by

    hauteanicole
    Metronidazole is an antibiotic and antiprotozoal drug used to treat various anaerobic bacterial infections and parasitic infections. It works by disrupting the DNA of anaerobic bacteria and protozoa. Common brand names include Flagyl. It is available in both oral and topical formulations. Metronidazole is indicated to treat conditions like bacterial vaginosis, rosacea, and trichomoniasis. Common side effects include nausea, vomiting, and metallic taste. Nursing responsibilities include monitoring for drug interactions and side effects.

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    Generic Name

    Metronidazole

    Flagyl, Metro, MetroCream, MetroGel, MetroGel-Vaginal, NidaGel,


    Brand Name
    Noritate, Vandazole
    Drug PHARMACOTHERAPEUTIC: Nitroimidazole derivative

    Classification CLINICAL: Antibacterial, Antiprotozoal

    It inhibits nucleic acid synthesis by disrupting the DNA of microbial


    cells. This function only occurs when metronidazole is partially
    Mechanism of
    reduced, and because this reduction usually happens only in
    Action
    anaerobic bacteria and protozoans, it has relatively
    little effect upon human cells or aerobic bacteria.
    Metronidazole Rosemont 200mg/5ml Oral Suspension
    Route & Dosage
    Metronidazole 200mg/5ml Oral Suspension
    Anaerobic Infections, Amebiasis, Giardiasis, Pseudomembranous
    Colitis, Trichomoniasis, Bacterial Vaginosis, Rosacea, Renal
    Indication
    Impairment & Hepatic Impairment

    Contraindications: Hypersensitivity to metronidazole. Pregnancy


    (first trimester with trichomoniasis), use of disulfiram within 2
    Contraindication
    weeks, use alcohol during therapy or within 3 days of
    discontinuing metronidazole.
    FREQUENT: Systemic: Anorexia, nausea, dry mouth, metallic
    taste. Vaginal: Symptomatic cervicitis/vaginitis, abdominal
    cramps, uterine pain. OCCASIONAL: Systemic: Diarrhea,
    constipation, vomiting, dizziness, erythematous rash, urticaria,
    Side Effects
    reddish-brown urine. Topical: Transient erythema, mild dryness,
    burning, irritation, stinging, tearing when applied too close to eyes.
    Vaginal: Vaginal, perineal, vulvar itching; vulvar swelling. RARE:
    Mild, transient leukopenia; thrombophlebitis with IV therapy.
    Adverse Effects Oral therapy may result in furry tongue, glossitis, cystitis, dysuria,
    pancreatitis. Peripheral neuropathy (manifested as numbness,
    tingling of hands/feet) usually is reversible if treatment is stopped
    immediately upon appearance of neurologic symptoms. Seizures
    occur occasionally.
    DRUG: Alcohol may cause disulfiram type reaction (e.g.,
    abdominal cramps, nausea, vomiting, headache, psychotic
    Drug Interaction reactions). Disulfiram may increase risk of toxicity. May increase
    effects of oral anticoagulants. HERBAL: None significant. FOOD:
    None known. LAB VALUES: May increase serum LDH, ALT, AST.
    Monitor daily pattern of bowel activity, stool consistency. Monitor
    I&O, assess for urinary problems. Avoid alcohol, alcohol-
    containing preparations (cough syrups, elixirs) for at least 48
    hours after last dose. Avoid tasks that require alertness, motor
    Nursing skills until response to drug is established. If taking metronidazole
    Responsibilities for trichomoniasis, refrain from sexual intercourse until full
    treatment is completed. Topical: Avoid contact with eyes. Other
    recommendations for rosacea include avoidance of hot/spicy
    foods, alcohol, extremes of hot/cold temperatures, excessive
    sunlight.

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