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    Quality Assessment of Diagnostic Accuracy Studies (Quadas)

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    Rilano Umboh
    The document describes the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool, which contains 14 questions used to assess study quality. Each question is scored 1 point for a "yes" answer, 0 points for "no", or 0 points for "unclear". Total scores can range from 0 to 14, with higher scores indicating higher quality. The questions address issues such as the representativeness of study patients, clear selection criteria, independent interpretation of reference standard and index tests, and reporting of results.

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    Quality Assessment of Diagnostic Accuracy Studies (Quadas)

    Uploaded by

    Rilano Umboh
    44 views3 pages
    The document describes the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool, which contains 14 questions used to assess study quality. Each question is scored 1 point for a "yes" answer, 0 points for "no", or 0 points for "unclear". Total scores can range from 0 to 14, with higher scores indicating higher quality. The questions address issues such as the representativeness of study patients, clear selection criteria, independent interpretation of reference standard and index tests, and reporting of results.

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    The document describes the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool, which contains 14 questions used to assess study quality. Each question is scored 1 point for a "yes" answer, 0 points for "no", or 0 points for "unclear". Total scores can range from 0 to 14, with higher scores indicating higher quality. The questions address issues such as the representativeness of study patients, clear selection criteria, independent interpretation of reference standard and index tests, and reporting of results.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    44 views3 pages

    Quality Assessment of Diagnostic Accuracy Studies (Quadas)

    Uploaded by

    Rilano Umboh
    The document describes the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) tool, which contains 14 questions used to assess study quality. Each question is scored 1 point for a "yes" answer, 0 points for "no", or 0 points for "unclear". Total scores can range from 0 to 14, with higher scores indicating higher quality. The questions address issues such as the representativeness of study patients, clear selection criteria, independent interpretation of reference standard and index tests, and reporting of results.

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    Quality Assessment of Diagnostic Accuracy Studies

    (QUADAS)

    Appendix E lists the questions asked to conduct the quality assessment of the included studies
    using the QUADAS tool.

    Total QUADAS score range = 0 – 14

    1. Was the spectrum of patients representative of the patients who will receive the test in practice?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    2. Were selection criteria clearly described?


    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    3. Is the reference standard and index test short enough to be reasonably sure that the target condition
    did not change between the two tests?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    4. Is the time period between reference standard and index test short enough to be reasonably sure
    that the target condition did not change between the two tests?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)
    5. Did the whole sample or a random selection of the sample, receive verification using a reference
    standard of diagnosis?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    6. Did patients receive the same reference standard regardless of the index test result?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    7. Was the reference standard independent of the index test (i.e. the index test did not form part of
    the reference standard)?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    8. Was the execution of the index test described in sufficient detail to permit replication of the test?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    9. Was the execution of the reference standard described in sufficient detail to permit its replication?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    10. Were the index test results interpreted without knowledge of the results of the reference standard?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    11. Were the reference standard results interpreted without knowledge of the results of the index test?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    12. Were the same clinical data available when test results were interpreted as would be available
    when the test is used in practice?
    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    13. Were uninterpretable/ intermediate test results reported?


    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

    14. Were withdrawals from the study explained?


    • Yes (score = 1)
    • No (score = 0)
    • Unclear (score = 0)

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