Chapter 21 Addq
Chapter 21 Addq
Chapter 21 Addq
1. A 75-year-old woman with history of angina is admitted to the hospital for syncope. Examination
of the patient reveals a systolic murmur best heard at the base of the heart that radiates into the carotid
arteries. Electrocardiogram (ECG) is notable for left ventricular hypertrophy with evidence of left
atrial enlargement. ECG reveals an aortic valve area of 0.7 cm. What is the most appropriate next step in
her management?
a. Medical management with a nitrate and an angiotensin-converting enzyme inhibitor
b. Bilateral carotid endarterectomies
c. Percutaneous coronary artery angioplasty and stenting
d. Coronary artery bypass surgery
e. Aortic valve replacement
2. A 63-year-old man is seen because of facial swelling and cyanosis, especially when he bends
over. There are large, dilated subcutaneous veins on his upper chest. His jugular veins are prominent
even while he is upright. Which of the following conditions is the most likely cause of these findings?
a. Histoplasmosis (sclerosing mediastinitis)
b. Substernal thyroid
c. Thoracic aortic aneurysm
d. Constrictive pericarditis
e. Bronchogenic carcinoma
3. A 45-year-old man with poorly controlled hypertension presents with severe chest pain radiating
to his back. An ECG demonstrates no significant abnormalities. A CT scan of the chest and abdomen
is obtained, which demonstrates a descending thoracic aortic dissection extending from distal to the
left subclavian takeoff down to above the iliac bifurcation. A Foley catheter is placed, and urine
output is 30 to 40 cc/h. His feet are warm, with less than 2-second capillary refill. Which of the
following is the most appropriate initial management?
a. Emergent operation for repair of the aortic dissection
b. Angiography to confirm the diagnosis of aortic dissection
c. Echocardiography to rule out cardiac complications
d. Initiation of a β-blocker
e. Initiation of a vasodilator such as nitroprusside
4. A 50-year-old salesman is on a yacht with a client when he has a severe vomiting and retching
spell punctuated by a sharp substernal pain. He arrives in your emergency room 4 hours later and has a
chest film in which the left descending aorta is outlined by air density. Which of the following is the
most appropriate next step in his workup?
a. Contrast esophagram
b. Echocardiogram
c. Flexible bronchoscopy
d. Flexible esophagogastroscopy
e. Aortography
The answer is a. The presence of air in the mediastinum after an
episode of vomiting and retching is virtually pathognomonic of spontaneous rupture of the esophagus
(Boerhaave syndrome). A contrast esophagram is the initial test of choice and is indicated with barium
for a suspected thoracic perforation and water-soluble contrast (Gastrografin) for an abdominal
perforation. Barium is inert in the chest but causes peritonitis in the abdomen, whereas aspirated
Gastrografin can cause severe pneumonitis. CT scanning may be useful if a small, contained leak is
suspected. A surgical endoscopy needs to be performed if the imaging studies are negative with a high
degree of suspicion for an esophageal injury. If the leak is contained and the patient does not have any
evidence of sepsis, then the leak can be managed with antibiotics and expectant management. For
leaks associated with systemic signs, patients should undergo prompt surgical therapy. The operation
of choice is dependent on the time to diagnosis. Leaks that are less than 24 hours old in patients
without an underlying esophageal disorder may be managed with thoracotomy, repair, and drainage.
Leaks older than 24 hours typically require more extensive surgery
5. A 26-year-old man is brought to the emergency room after being extricated from the driver ’s seat
of a car involved in a head-on collision. He has a sternal fracture and is complaining of chest pain. He
is hemodynamically stable and his electrocardiogram (ECG) is normal. Which of the following is the
most appropriate management strategy for this patient?
a. Admit to telemetry for 24-hour monitoring
b. Admit to the regular ward with serial ECGs for 24 hours
c. Emergent cardiac catheterization
d. Immediate operative plating of the sternal fracture
e. Discharge to home with nonsteroidal anti-inflammatory agents for the sternal fracture
6. A 63-year-old man underwent a 3-vessel coronary artery bypass graft (CABG) 5 hours ago.
Initially, his mediastinal chest tube output was 300 mL blood/h, but an hour ago, there was no further
evidence of bleeding from the tube. His mean arterial pressure has fallen, and several fluid boluses
were administered. His central venous pressure (CVP) is elevated to 20 mm Hg, and he has required
the addition of inotropes. Which of the following is the best management strategy?
a. Addition of vasopressors along with the inotropes
b. Transfusion of packed red blood cells
c. Return to the operating room for exploration of the mediastinum
d. Placement of an intraaortic balloon pump
e. Infusion of streptokinase into the mediastinal chest tube
7. A 56-year-old woman presents for evaluation of a murmur suggestive of mitral stenosis and is
noted on echocardiography to have a lesion attached to the fossa ovalis of the left atrial septum. The
mass is causing obstruction of the mitral valve. Which of the following is the most likely diagnosis?
a. Endocarditis
b. Lymphoma
c. Cardiac sarcoma
d. Cardiac myxoma
e. Metastatic cancer to the heart
8. A 59-year-old man is found to have a 6-cm thoracoabdominal aortic aneurysm which extends to
above the renal arteries for which he desires repair, but he is concerned about the risk of paralysis
postoperatively. Which of the following maneuvers should be employed to decrease the risk of
paraplegia after repair?
a. Infusion of a bolus of steroids immediately postoperatively with a continuous infusion for 24 hours
b. Maintenance of intraoperative normothermia
c. Clamping of the aorta proximal to the left subclavian artery
d. Cerebrospinal fluid (CSF) drainage
e. Extracorporeal membrane oxygenation
9. A 70-year-old woman undergoes a cardiac catheterization for exertional chest pain. Her pain
continues to worsen and she is interested in having either surgery or percutaneous coronary
intervention (PCI). Which of the following would be an indication for her to undergo either coronary
artery bypass grafting or PCI?
a. Two-vessel coronary disease with proximal left anterior descending artery stenosis and depressed
left ventricular ejection fraction
b. Isolated left main stenosis, no diabetes, and normal left ventricular ejection fraction
c. Isolated left main stenosis and diabetes
d. Left main stenosis and additional coronary artery disease with depressed left ventricular ejection
fraction.
e. Three-vessel coronary artery disease and diabetes
10. A 27-year-old woman seeks your advice regarding pain and numbness in the right arm and hand.
She reports that it is exacerbated by raising her arm over her head. On examination, the right radial
pulse disappears when the patient takes a deep breath and turns her head to the left. A provisional
diagnosis is made. Which of the following is the most appropriate initial treatment for this patient?
a. Physical rehabilitation
b. Gabapentin to treat neuropathic pain
c. Right first rib resection
d. Thoracoscopic sympathectomy
e. Upper thoracic discectomy
11. An elderly man with abnormal pupillary responses (Argyll Robertson pupil).
a. Massive tricuspid regurgitation
b. Aortic regurgitation
c. Coarctation of the aorta
d. Thoracic aortic aneurysm
e. Myocarditis
12. A 24-year-old drug addict with jugular venous distention and exophthalmos.
a. Massive tricuspid regurgitation
b. Aortic regurgitation
c. Coarctation of the aorta
d. Thoracic aortic aneurysm
e. Myocarditis
14. A patient with flushing and paling of the nail beds (Quincke pulse) and a bounding radial pulse.
a. Massive tricuspid regurgitation
b. Aortic regurgitation
c. Coarctation of the aorta
d. Thoracic aortic aneurysm
e. Myocarditis
18. A patient with short stature, webbed neck, low-set ears, and epicanthal folds
a. Massive tricuspid regurgitation
b. Aortic regurgitation
c. Coarctation of the aorta
d. Thoracic aortic aneurysm
e. Myocarditis
19. A 56-year-old man presents with a blood pressure of 220/110 mm Hg, chest pain, and ST
elevations on an ECG.
a. Epinephrine
b. Norepinephrine
e. Dobutamine
f. Nitroprusside
g. Nitroglycerin
20. A 65-year-old man presents with cardiogenic shock following a myocardial infarction.
a. Epinephrine
b. Norepinephrine
e. Dobutamine
f. Nitroprusside
g. Nitroglycerin
21. A 30-year-old man presents with perforated appendicitis and heart rate of 120 beats per minute,
blood pressure of 80/40 mm Hg, and central venous pressure of 17 mm Hg. The patient remains
hypotensive after a continuous infusion of dopamine
a. Epinephrine
b. Norepinephrine
e. Dobutamine
f. Nitroprusside
g. Nitroglycerin
22. A 21-year-old man undergoes major abdominal surgery after a motor vehicle collision. He has a
cardiac arrest in the intensive care unit shortly after returning from surgery.
a. Epinephrine
b. Norepinephrine
e. Dobutamine
f. Nitroprusside
g. Nitroglycerin
23. A 45-year-old woman presents with a blood pressure of 220/130 mm Hg and a headache. After
several hours of an intravenous drip of medication to control her hypertension, she becomes acidotic.
a. Epinephrine
b. Norepinephrine
e. Dobutamine
f. Nitroprusside
g. Nitroglycerin
Epinephrine is a circulating endogenous catecholamine, released mainly from the adrenal medulla,
whose effects are mediated by binding of free circulating hormone to β
1
and β
receptors, with lesser
effects on α adrenoreceptors. At low infusion rates the β
1
2
-adrenergic effects predominate causing
increased heart rate, stroke volume, and contractility. At higher infusion rates, α-adrenergic receptors
are stimulated, resulting in an increase in blood pressure and systemic vascular resistance. Prolonged
use of high-dose epinephrine is limited by renal and splanchnic vasoconstriction, cardiac
dysrhythmias, and increased myocardial oxygen demand. Norepinephrine is also endogenously
produced, but acts locally through release at nerve synapses. It acts on α-adrenergic and β-adrenergic
receptors, resulting in an increase in afterload and glomerular perfusion pressure with preservation of
cardiac output. Norepinephrine is associated with increase in urine output in hypotensive, septic
patients. Dopamine is an endogenous catecholamine that is released into the circulation and acts by
binding to α
receptors as well as to specific dopamine receptors in the renal, mesenteric, coronary,
and intracerebral vascular beds, causing vasodilation. It has effects that change with increasing doses
1
by binding to different receptors. At low serum concentrations, dopamine binds to dopaminergic
receptors in the renal and splanchnic beds leading to increased urine output and natriuresis. At modest
concentrations, dopamine binds to cardiac β
-adrenergic receptors leading to increased myocardial
contractility and increased heart rate. At high doses, dopamine binds to α-adrenergic receptors and
1
causes an increase in blood pressure and peripheral vascular resistance. Dopamine is an effective
agent in increasing blood pressure in hypotensive patients with adequate fluid resuscitation.
Dobutamine is a synthetic catecholamine that predominately binds to β-adrenergic receptors and
enhances myocardial contractility with minimal changes in heart rate. It is often used in treatment of
cardiogenic shock following myocardial infarction to support myocardial contractility while reducing
peripheral resistance. Phenylephrine is a pure α-agonist and its use results in increased peripheral
vascular resistance and blood pressure. The increase in afterload increases left ventricular work and
oxygen demand, and may cause a decrease in stroke volume and cardiac output. Nitroprusside is an
arterial and venous smooth muscle vasodilator. Continuous infusions of nitroprusside require
monitoring of serum thiocyanate levels and arterial pH for cyanide toxicity. Nitroglycerin is primarily
a venous smooth muscle vasodilator. It is an effective treatment for myocardial ischemia because it
diminishes myocardial oxygen demand by reducing excessive preload and ventricular end-diastolic
pressure.
24. What is the most commonly used device for mechanical circulatory support, and it may be easily
deployed in the catheterization laboratory, in the operating room or at the bedside?
A. Intra-Aortic Balloon Pump
B. Total Artificial Heart
C. Right Ventricular Assist Devices
D. Biventricular Assist Devices
ANSWER: A
Intra-Aortic Balloon Pump is the most commonly used device for mechanical circulatory support, and it
may be easily deployed in the catheterization laboratory, in the operating room or at the bedside. The
device is inserted percutaneously through the femoral artery into the thoracic aorta.
25. Which of the following is characterized by infiltration of the cellular and fibrous pericardium by
inflammatory cells. It is found in approximately 1% of autopsies and accounts for up to 5% of
presentations of nonischemic chest pain.
A. Myocardial Infarction
B. Acute Pericarditis
C. Myocarditis
D. Rheumatic heart disease
ANSWER: B
Acute pericarditis is characterized by infiltration of the cellular and fibrous pericardium by inflammatory
cells. It is found in approximately 1% of autopsies and accounts for up to 5% of presentations of
nonischemic chest pain. It requires the identification of at least two of four cardinal features:
Pleuritic and positional, retrosternal chest pain
Pericardial friction rub
EKG changes: diffuse ST elevation and PR depression
Pericardial effusion
26. Heart Rhythm Society state that surgical ablation for atrial fibrillation is indicated for the following
EXCEPT:
A. All symptomatic AF patients undergoing other cardiac surgery
B. Selected asymptomatic AF patients undergoing cardiac surgery in which the ablation can be
performed with minimal additional risk
C. Symptomatic patients with lone AF who have failed medical therapy and prefer a surgical approach,
have failed one or more attempts at catheter ablation, or are poor candidates for catheter ablation
D. None of the above
ANSWER: D
27. True of Cox-Maze IV Procedure
A. First successful operation for supraventricular tachycardia
B. Clinically introduced in 1987 by James Fox
C. Procedure involved the completion of a zigzag-like pattern of surgical incisions across both the right
and left atrial that were designed to interrupt the multiple macroreentrant circuits that were thought to
be responsible for AF
D. It is performed on cardiopulmonary bypass through either a median sternotomy, often in
combination with other cardiac surgery, or a right minithoracotomy
ANSWER: D
It is the first successful operation for atrial fibrillation and was clinically introduced in 1987 by James
Cox. Procedure involved the completion of a maze-like pattern of surgical incisions across both the right
and left atrial that were designed to interrupt the multiple macroreentrant circuits that were thought to
be responsible for AF. It is performed on cardiopulmonary bypass through either a median sternotomy,
often in combination with other cardiac surgery, or a right minithoracotomy.
28. It is the mainstay imaging technique for the detection of cardiac tumors
A. Transesophageal echocardiography
B. Cardiac MRI
C. Transthoracic echocardiography
D. CT scans
ANSWER: C
Transthoracic echocardiography is the mainstay imaging technique for the detection of cardiac tumors
Transesophageal echocardiography is generally only beneficial for small localized tumors due to its
limited field of view
Cardiac MRI is therefore the current standard for delineating the anatomical extent of the tumor and
assessing the paracardiac space and great vessels
CT scans include better soft-tissue evaluation without the need for iodinated contrast and no exposure
to ionizing radiation
ANSWER: B
The basic CPB circuit consists of:
- venous cannulae
- venous reservoir
- pump
- oxygenator
- filter
- arterial cannula
ANSWER: D
The 1st saphenous vein CABG was performed by Sabiston in 1962, popularized by Favalaro in 1967
1968 Bypass conduit by Green
Sening described the use of vein patches to repair arteriostomy sites in 1961