Acute kidney injury (AKI), previously called acute renal failure, is a rapidly progressive loss of renal function characterized by decreased urine production and disturbances to body water and fluids and electrolyte levels. AKI can be caused by problems affecting blood flow to the kidneys or from toxins overwhelming the kidneys. Symptoms of AKI include changes to urination, fluid retention, fatigue, confusion and other issues stemming from the kidneys' inability to filter waste from the blood. Dialysis may be necessary to support kidney function until the underlying cause of AKI can be addressed and the kidneys can potentially recover.
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Acute kidney injury (AKI), previously called acute renal failure, is a rapidly progressive loss of renal function characterized by decreased urine production and disturbances to body water and fluids and electrolyte levels. AKI can be caused by problems affecting blood flow to the kidneys or from toxins overwhelming the kidneys. Symptoms of AKI include changes to urination, fluid retention, fatigue, confusion and other issues stemming from the kidneys' inability to filter waste from the blood. Dialysis may be necessary to support kidney function until the underlying cause of AKI can be addressed and the kidneys can potentially recover.
Acute kidney injury (AKI), previously called acute renal failure, is a rapidly progressive loss of renal function characterized by decreased urine production and disturbances to body water and fluids and electrolyte levels. AKI can be caused by problems affecting blood flow to the kidneys or from toxins overwhelming the kidneys. Symptoms of AKI include changes to urination, fluid retention, fatigue, confusion and other issues stemming from the kidneys' inability to filter waste from the blood. Dialysis may be necessary to support kidney function until the underlying cause of AKI can be addressed and the kidneys can potentially recover.
Copyright:
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Download as DOCX, PDF, TXT or read online from Scribd
Acute kidney injury (AKI), previously called acute renal failure, is a rapidly progressive loss of renal function characterized by decreased urine production and disturbances to body water and fluids and electrolyte levels. AKI can be caused by problems affecting blood flow to the kidneys or from toxins overwhelming the kidneys. Symptoms of AKI include changes to urination, fluid retention, fatigue, confusion and other issues stemming from the kidneys' inability to filter waste from the blood. Dialysis may be necessary to support kidney function until the underlying cause of AKI can be addressed and the kidneys can potentially recover.
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Acute kidney injury
Main article: Acute kidney injury
Acute kidney injury (AKI), previously called acute renal failure (ARF), is a rapidly progressive loss of renal function, generally characterized by oliguria (decreasedurine production, quantified as less than 400 mL per day in adults,[1] less than 0.5 mL/kg/h in children or less than 1 mL/kg/h in infants); body water and body fluids disturbances; and electrolyte derangement. AKI can result from a variety of causes, generally classified as prerenal, intrinsic, and postrenal. An underlying cause must be identified and treated to arrest the progress, and dialysis may be necessary to bridge the time gap required for treating these fundamental causes. Symptoms Symptoms can vary from person to person. Someone in early stage kidney disease may not feel sick or notice symptoms as they occur. When kidneys fail to filter properly, waste accumulates in the blood and the body, a condition called azotemia. Very low levels of azotaemia may produce few, if any, symptoms. If the disease progresses, the symptoms become noticeable. Renal failure accompanied by noticeable symptoms is termed uraemia. Symptoms of kidney failure include:
High levels of urea in the blood, which can result in:
Vomiting and/or diarrhea, which may lead to dehydration Nausea Weight loss Nocturnal urination Foamy or bubbly urine More frequent urination, or in greater amounts than usual, with pale urine Less frequent urination, or in smaller amounts than usual, with dark colored urine Blood in the urine Pressure, or difficulty urinating
A build up of phosphates in the blood that diseased kidneys cannot
filter out may cause: Itching Bone damage Muscle cramps (caused by low levels of calcium which can cause hypocalcaemia)
A build up of potassium in the blood that diseased kidneys cannot
filter out (called hyperkalemia) may cause: Abnormal heart rhythms Muscle paralysis
Failure of kidneys to remove excess fluid may cause:
Swelling of the legs, ankles, feet, face and/or hands Shortness of breath due to extra fluid on the lungs (may also be caused by anemia)
Polycystic kidney disease, which causes large, fluid-filled cysts on
the kidneys and sometimes the liver, can cause: Pain in the back or side
Healthy kidneys produce the hormone erythropoietin which
stimulates the bone marrow to make oxygen-carrying red blood cells. As the kidneys fail, they produce less erythropoietin, resulting in decreased production of red blood cells to replace the natural breakdown of old red blood cells. As a result, the blood carries less hemoglobin, a condition known as anemia. This can result in: Feeling tired and/or weak Memory problems Difficulty concentrating Dizziness Low blood pressure
Other symptoms include:
Appetite loss, a bad taste in the mouth Difficulty sleeping Darkening of the skin Causes of acute renal failure Acute kidney failure usually occurs when the blood supply to the kidneys is suddenly interrupted or when the kidneys become overloaded with toxins. Causes of acute failure include accidents, injuries, or complications from surgeries in which the kidneys are deprived of normal blood flow for extended periods of time. Heart-bypass surgery is an example of one such procedure. Drug overdoses, whether accidental or from chemical overloads of drugs such as antibiotics or chemotherapeutics, may also cause the onset of acute kidney failure. Unlike in chronic kidney disease, however, the kidneys can often recover from acute failure, allowing the patient to resume a normal life. People suffering from acute failure require supportive treatment until their kidneys recover its function and they often remain at increased risk of developing future kidney failure.