Activity Sheets Science 7 Quarter 1 Week 1

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The passages discuss two scientific investigations - one into beriberi by Dr. Eijkman and one into penicillin by Sir Alexander Fleming.

Dr. Eijkman investigated what caused beriberi.

Fleming hypothesized that the mold must be producing a chemical that killed the bacteria.

First Quarter

WEEK 1
Diversity of Materials in the Environment
Components of a Scientific Investigation

Activity 1

I. Complete the following statements.


Activity 2

Scientific Method In Action

I. Answer the following question based on the scenarios given

A. The Strange Case of BeriBeri

In 1887 a strange nerve disease attacked the people in the Dutch East Indies. The disease was
beriberi. Symptoms of the disease included weakness and loss of appetite, victims often died of heart
failure. Scientists thought the disease might be caused by bacteria. They injected chickens with
bacteria from the blood of patients with beriberi. The injected chickens became sick. However, so did
a group of chickens that were not injected with bacteria.

One of the scientists, Dr. Eijkman, designed a new experiment based on his own observations.
Before the experiment, all the chickens had eaten whole-grain rice, but during the experiment, the
chickens were fed polished rice. Dr. Eijkman researched this interesting case and found that polished
rice lacked thiamine, a vitamin necessary for good health.

1. State the question or problem that Dr. Eijkman investigated.


2. What was the original hypothesis?
3. What was the manipulated (independent) variable and the ressponding (dependent) variable?
4. Write a statement that summarizes the results of the experiment.
5. How would Dr. Eijkman test his new hypothesis?

B. How Penicillin Was Discovered

In 1928, Sir Alexander Fleming was studying Staphylococcus bacteria growing in culture dishes. He
noticed that a mold called Penicillium was also growing in some of the dishes. A clear area existed
around the mold because all the bacteria that had grown in this area had died. In the culture dishes
without the mold, no clear areas were present.

Fleming hypothesized that the mold must be producing a chemical that killed the bacteria. He
decided to isolate this substance and test it to see if it would kill bacteria. Fleming transferred the
mold to a nutrient broth solution. This solution contained all the materials the mold needed to grow.
After the mold grew, he removed it from the nutrient broth and then added the broth to a culture of
bacteria. He observed that the bacteria in the culture died. Fleming's experiments were later used to
develop antibiotics.

6. State the question or problem that Fleming investigated.


7. What was Fleming's hypothesis?
8. How was the hypothesis tested?
9. Write a statement that summarizes the results of the experiment.
10. This experiment lead to the development of what major medical advancement?

Activity 3
I. Connect the right meaning of
the steps of scientific method

Prepared by:

Renee Lyn C. Paderes


Teacher I

Checked by: Approved by:


Jennilyn S. De La Cruz MELISSA M. MARTIN
Teacher I/Coordinator Head Teacher VI/OIC

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