Valvular Heart Disease
Valvular Heart Disease
Mitral Stenosis
Causes
Chronic Rheumatic Heart Disease (99% cause)
Age >70 – Degenerative valvular heart disease
History of – joint pain, sore throat (5-15 years old),
Symptoms
Palpitation (arrhythmia)
Shortness of breath (Dyspnoea on exertion, PND, Orthopnoea)
Poor effort tolerance (due to HF, Pulmonary HTN)
Stroke, TIA, Ischemic Limb, Gangrene – Thromboembolism
Pink frothy sputum
Signs
Young age – CRHD
Old Age – Fibrosis
Features of stroke
Amputation of leg
Low volume pulse
Atrial Fibrillation (irregularly irregular)
BP – normal unless with comorbid HTN
JVP – not raised, Elevated in CCF
Loss of ??? wave
Malar flush
Bilateral pitting oedema
Tachypnoea
Epigastric pulsation – RVH
Left Lower Parasternal heaves – RVH
Apex Beat (not displaced) – tapping character (palpable S1)
Thrills on mitral (Grade 4)
Palpable P2 – Pulmonary HTN
Loud P2 – Pulmonary HTN
Heart Sound – Loud S1
Added Sound – Mid Diastolic murmur (there is a murmur I heard more marked in the
mitral area which is mid diastolic murmur of Grade 3/4 and heard more with left
lateral on expiration), Opening Snap (Absent of snap indicates calcified)
Bibasal Crepitation - Pulmonary oedema (HF)
Differential Diagnosis
Triscupid Stenosis
Atrial Myxoma
Investigation
ECG – Normal, AF (narrow complex tachycardia, irregularly irregular, loss P waves), P
Mitrale/Broad Bifid P, Tall R in V1, V2 - RVH
CXR – Pulmonary Oedema (ground glass appearance), Straightening of Left, Double
Shadow in LA dilatation, widening of angle of carina, Calcified valve.
Echocardiogram with Doppler (confirmatory) – LA dilatation, LA thrombus,
Pulmonary HTN, Heart Failure
Cardiac Catheterization – measure pressure in chamber
Management
Avoid vigorous exercise
Avoid fluid and salt rich food
Prophylaxis against rheumatic fever
No need IE Prophylaxis to be given
Heart failure treatment – Diuretic, ACE Inhibitor
Anti Coagulant based on CHADSVAS Score
Valvotomy/Valvuloplasty –
Valve Replacement –
Complication
Heart Failure
Atrial Fibrillation
Thromboembolic Episodes
Mitral Regurgitation
Causes
Acute – MI, IE, Chest Trauma, Chest Surgery, Cardiac Intervention
Chronic – CRHD, Autoimmune(RA, SLE, Ankylosing Spondyliosis), Marfan Syndrome
Symptoms
Same as Mitral Stenosis
Both LV and LA on pressure, LA>LV
Signs
Pulse – normal, Irregularly Irregular (AF)
JVP – Same as MS
BP – same as MS
Inspection – visible apex beat
Palpation – displace apex beat, forceful ill sustained, thrill (more common in systolic
murmur)
Auscultation – normal or soft heart sound, loud S2 in Pulmonary HTN, Pansystolic
murmur more marked in mitral area, radiating to axilla, associated with thrill and
accentuated with expiration
Investigation
ECG - LVH
Echocardiogram – vegetation
Management
Valve replacement
Aortic Stenosis
Causes
Bicuspid aortic valve
Chronic rheumatic heart disease
Calcification or Firbrosis
Symptoms
Angina Jolie
Syncope
Sudden cardiac death
Palpitation
Poor effort tolerance
Fatigue
Signs
Pulse – low volume pulse, AF(irregularly irregular)
BP – Narrow pulse pressure (more narrow, more severe)
JVP – normal, raised if CCF
Inspection –
Palpation – Displace outward, pressure heaving, thrills in aortic
Auscultation – normal S1, soft S2 (HF), ESM at aortic area accentuated inspiration,
radiate to neck, bibasal fine crepitation (LVF)
Investigation
ECG – LVH (findings)
Echo with Doppler – cardiac chamber, vegetation,
CXR – Pulmonary Oedema, Kerly B Line, Bat wing Appearance, cardiomegaly, upper
lobe diversion
Cardiac Cathetherization – angiogram to rule out IHD, ejection fraction
Management
Prophylaxis to IE
Manage HF, Arrythmia
1 episode of syncope – immediate surgery aortic valve replacement
Anticoagulants
Aortic Regurgitation
Causes
CRHD
IC
Autoimmune
Marfan
Carcinoid Syndrome
Chest Trauma/Surgery
Symptoms
Palpitation
Poor effort tolerance
Angina
Syncope
SCD
HF
Signs
Pulse – high volume collapsing pulse, AF (Irregularly irregular)
BP – wide pulse pressure
JVP –
Inspection – hyperdynamic precordium, visible pulsation (apical)
Palpation – displaced outward and downwards, thrusting, thrill in aortic
area(unusual)
Auscultation – normal S1, soft in HF, normal S2, EDM accentuate on forward leaning
on inspiration at LLPS, bilateral fine crept, galloping rhythm (LVF)
Investigation
ECG
Echocardiogram with Doppler
CXR
Cardiac Cathetherization
Management
IE Prophylaxis
Valve Replacement
Summary
Causes
Stenosis – CRHD, Degenerative Fibrosis (Calcification)
Regurgitation – CRHD, IE, Autoimmune, Marfan, Cardiac Trauma / Surgery
MR – Myocardial Infarction
Symptoms
Palpitation
Poor effort tolerance
Complication
CCF – MR, MS ---Thromboembolism
LVF – AS, MR, AR
Findings
Pulse – AF in all cases
o MS – low volume
o MR – normal
o AS –
o AR – high volume pulse,
BP –
o MS –
o MR –
o AS –
o AR –
JVP
o Raised in CCF
o Loss of A waves – AF
Condition on LV
o MS – no load
o MR – volume
o AS – Pressure
o AR – Volume
Apex Beat
o Volume overload – outward, downward, thrusting (forceful ill-sustained)
o Pressure overload – outward, heaving (forceful well sustained)
o MS
o MR
o AS
o AR
Heart Sound
o MS – normal s1, loud s2 in PHTN
o MR – normal s1 , loud s2 in phtn
o AS – normal s1 , soft s2 in hf
o AR – normal s1,s2
Murmur
o MS – MDM
o MR – PSM
o AS – ESM
o AR – EDM
Differential
o MS – TS, AR
o MR – TR, VSD
o AS – PS
o AR - PR