Aortic Stenosis: Sherif EL Hawary, MD

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AORTIC STENOSIS

Question:
- What is your diagnosis??

Answer:

- Congenital heart disease.


- Aortic valve disease, aortic stenosis.
- Compensated on treatment.
- Not complicated.

Question:
- Why did you diagnose the aetiology as Congenital heart disease??
Answer:
 There is absent history of Rheumatic Fever RF.
 There is history of positive consanguinity.
 The onset of the disease started early in childhood.

Question:
- What is the most common cause of AS ??
Answer:
- Rheumatic Fever, Congenital, Calcific.

Question:
- What are the other causes of AS that you know??
Answer:
Hypertrophic cardiomyopathy (Idiopathic hypertrophic subaortic stenosis ; IHSS):
- It produces a subvalvular obstruction in the systole due to the contraction of the
hypertrophied interventricular septum.

Relative stenosis (not an organic stenosis):


a) Dilatation of the aorta:
Hypertension, atherosclerosis & aortic aneurysm.
b) Increased blood flow across the aortic valve: Hyperdynamic circulation, AR.

Question:
- What are the types of congenital AS that you know??
Answer:
- It may be: valvular, subvalvular or supravalvular.

Sherif EL Hawary, MD
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Question:
- How could you differentiate between the 3 main causes of AS ??
Answer:

Congenital Rheumatic Calcific


Age Young Middle Old
History of RF Absent Present Absent
Type Valvular or subvalvular Valvular Valvular
or supravalvular
Associations Congenital anomalies Other valvular lesions Atherosclerosis

Question:
- Why did you diagnose the case clinically as AS lesion??
Answer:
- Because there is clinical evidence of AS in the form of:

From history
- Symptoms of low CO ( dizziness, blurring of vision ). - Angina & exertional syncope.
_____________________________________________________________________________

From general examination:


___________________________________________________________________________________________________________________
- Slight pallor.
- Pulse: weak (small volume), plateau.
- BP: low systolic.
- Neck:
o Neck veins: normal.
o Carotid arteries: systolic thrill originating from the base of the heart.
From precordial examination
- Signs of LV enlargement.
- Heaving apex.
- Systolic thrill over the second right space propagated to the carotid.

From auscultation
- Over the aortic area:
1. Second heart sound: weak.
2. Systolic ejection click: due to opening of the rigid cusps.
3. Systolic ejection murmur:
- Midsystolic, harsh, grade IV.
- Maximum over the second right space & propagated to the apex & carotid arteries.
- Over the pulmonary area: Reversed splitting of the second hesrt sound.
- Over the mitral area:
1. Propagated murmur of aortic stenosis.
2. S4.

Sherif EL Hawary, MD
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Question:
- What is the main presenting symptom of AS ??
Answer:
- Symptoms of low CO especially Angina & exertional syncope.

Question:
- Why is S2 weak in the patient with AS??
Answer:
 Due to presence of low pressure over the aortic cusps which will close weakly.

Question:
- What do you expect to find in examination of the pulse in AS ??
Answer:
- Pulsus parvus et tardus (plateau pulse): rises slowly, of small volume, returns
slowly.
- Pulsus bisferiens: bifid pulse occurring in double aortic lesion with predominant AR.

Question:
- How do you explain the presence of bradycardia in a patient with AS ??
Answer:
- Complication by heart block that may occur in patients with calcific AS due to extension of
calcification to the AV bundle.

Question:
- What causes angina in AS ??
Answer:
- Reduced coronary blood flow: due to low CO & shortened diastole.
- Left ventricular hypertrophy: increases the myocardial O2 demands.
- Associated coronary aterosclerosis: especially in calcific AS.

Question:
- What are the valvular diseases that present with angina ??
Answer:
- AS & AR.

Question:
- In which condition is S2 normal in AS ??
Answer:
- In cases of AS which are associated with AR (double aortic).

Question:
- What additional sound can you hear in AS ??
Answer:
- Systolic ejection click: due to opening of the rigid cusps.

Sherif EL Hawary, MD
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Question:
- What can you hear over the mitral area in this patient ??
Answer:
1. S4.
2. Propagated murmur of aortic stenosis.

Question:
- What can you hear over the pulmonary area in this patient ??
Answer:
- Reversed splitting of the second heart sound.

Question:
- What type of heart failure can occur in AS, left-sided or right-sided??
Answer:
- Left-sided heart failure due to left ventricular failure & pulmonary congestion.. However,
Right-sided heart failure can also occur late secondary to left-sided heart failure.

Remember: Left-sided heart failure is the most common cause of Right-sided heart failure.

Question:
- What other complications of AS do you know ??
Answer:
1. LVF.
2. Infective endocarditis.
3. Sudden death: usually due to VF.
4. Heart block: in calcific stenosis due to extension of calcification to the AV bundle.
5. Rheumatic activity: in rheumatic AS.

Question:
- What is the most important investigation of AS ??
Answer:
- Echo cardiography.
Question:
- What do you expect to find in the chest x-ray of a patient with AS ??
Answer:
- No abnormality: in mild cases.
- LV: LVH.
- Lungs: Pulmonary congestion when LVF occurs.
- Small aortic knuckle or post-stenotic dilatation.
- Aortic valve calcification may be seen.

Sherif EL Hawary, MD
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Question:
- What do you expect to find in the ECG of a patient with AS ??
Answer:
- Left ventricular enlargement.

Question:
- How would you proceed to manage this case??
Answer:
1. I would ask for echocardiography to prove my diagnosis of aortic stenosis lesion.
2. I would then start treatment which could be:
- medical or - surgical ( refer to the book ).

Question:
- When would you ttt this patient surgically ??
Answer:
- Indications of surgery in AS: (aortic valve replacement):
1. Presence of symptoms.
2. Pressure gradient more than 50 mmHg.
3. Valve area less than 0.8 cm2 ( normally: 3-4 cm2 ).

Most important points in pure Aortic Stenosis

▪ The most common cause is: Rheumatic Fever, Congenital, Calcific.


▪ The most common symptom is: Angina & syncope.
▪ The most important precordial sign is: systolic thrill over the second right space.
▪ The most important auscultatory sign is: systolic ejection murmur over the second right space.

Sherif EL Hawary, MD
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Sherif EL Hawary, MD

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