BIOL 2520 Course-Syllabus-2019

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The key takeaways are that this course will provide an overview of cell biology focusing on molecular, biochemical, and physiological aspects of eukaryotic cells. The course will cover topics such as macromolecules, cell cycle, DNA structure and transcription, membrane structure and transport, cell signaling, energetics and metabolism.

The course will cover topics such as macromolecules, cell cycle, DNA structure and transcription, endomembrane system, Golgi apparatus, lysosomes, plasma membrane structure and transport, cell signaling pathways, cytoskeleton structure and function, cell interactions, cancer, and apoptosis.

Students are expected to come to lectures prepared having read the assigned readings. They should take notes during lectures and seek clarification on concepts they do not understand by reading textbooks or scheduling meetings with the instructor. Students are not allowed to record lectures without permission.

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COURSE DETAILS

Course Title & Number: BIOL 2520 – Cell Biology

Number of Credit Hours: 3

Class Times & Days of Week: Mon-Wed-Fri 10:30-11:20

Location for 172 Robert B. Shultz


classes/labs/tutorials:

Pre-Requisites: BIOL 1020

Instructor Contact Information


Instructor(s) Name: Dr. Steve Whyard

Preferred Form of Address: Dr. Whyard


Office Location: Buller 525

Office Hours or Availability: Available to meet MWF from 11:30-12:00, or email to make
an appointment
Office Phone No. 204-474-9418

Email: All email communication must conform to the Communicating


with Students university policy.
I will reply to an email-within 24 hrs
Contact: If I am not in the office following the lectures, please make an
appointment to meet by email.
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Course Description

A survey of cell biology. Focus is on an integrative examination of the structure and function of
subcellular compartments, organelles, and key molecules. The course attempts to explain how
the cell functions and how it interacts with other cells and its environment.

General Course Information


This course will provide the student with an overview of the importance of cells in living
organisms, focusing on molecular, biochemical, and physiological aspects of cells in eukaryotic
organisms. The course is required for all Biological Sciences and Microbiology Majors and
Honours, and is strongly recommended for Biochemistry Majors/Honours. The course is an
introductory cell biology course, and hence will not cover any particular aspect of cell biology in
great depth, but will provide students with sufficient background to pursue more in-depth
aspects of cell and molecular biology in subsequent courses.

Using Copyrighted Material


Please respect copyright. We will use copyrighted content in this course. I have ensured that
the content I use is appropriately acknowledged and is copied in accordance with copyright
laws and University guidelines. Copyrighted works, including those created by me, are made
available for private study and research and must not be distributed in any format without
permission. Do not upload copyrighted works to a learning management system (such as UM
Learn), or any website, unless an exception to the Copyright Act applies or written permission
has been confirmed. For more information, see the University’s Copyright Office website at
http://umanitoba.ca/copyright/ or contact um_copyright@umanitoba.ca.

Recording Class Lectures


The student is expected to take notes during lectures, but no audio or video recording of the
meetings is allowed in any format, openly or surreptitiously, in whole or in part without
permission of Dr. Steve Whyard.  Course materials, provided online, are for the participant’s
private study and research.

Textbook, Readings, Materials

Essential Cell Biology – 5th edition, by Alberts et al. The syllabus indicates the suggested
readings. These readings are intended to help you understand the material covered in class. If
you do not understand the lecture material, please read the textbook for clarification. You are
not expected to know the material in the textbook beyond what is covered in class, but
knowing more than what is covered in lectures is always useful!
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Class Communication
The University requires all students to activate an official University email account.  For full
details of the Electronic Communication with Students please visit:
http://umanitoba.ca/admin/governance/media/Electronic_Communication_with_Students_Pol
icy_-_2014_06_05.pdf

Please note that all communication between myself and you as a student must comply with the
electronic communication with student policy
(http://umanitoba.ca/admin/governance/governing_documents/community/electronic_communic
ation_with_students_policy.html). You are required to obtain and use your U of M email
account for all communication between yourself and the university.

Expectations: I Expect You To


You are expected to come to lectures with a hard copy or electronic version of the class notes
available at your seat. You should take note of extra material that I talk about during classes, as
this material, along with the notes provided online, comprise the material on which you will be
examined. You are encouraged to ask some questions during class, but if I note that there are
few too many questions to answer during the lecture, I will ask you to visit me at the end of the
lecture, either immediately after class or in my office several minutes later.

If you do not fully understand some aspect of the course material, and you could not get
clarification directly after class, you should first read the text book or access online sources
before making an appointment or sending me an email with your questions. I would like to see
evidence that you have made some effort to find answers to your questions on your own, and
for you to define as clearly as possible what you do not understand. If you make an effort to
seek answers independently, I will be more than happy to help you understand the material
more fully.

Academic Integrity:

The Faculty of Science takes academic integrity very seriously. Any evidence of academic
dishonesty on assignments, labs and/or tests will be forwarded to the appropriate authorities
for potential disciplinary actions.

The University Student Discipline By‐Law may be accessed at:


http://umanitoba.ca/admin/governance/governing_documents/students/student_discipline.ht
ml. Information from the Faculty of Science regarding Cheating and Plagiarism can be found at
http://umanitoba.ca/faculties/science/undergrad/resources/webdisciplinedocuments.html.
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Expectations: You Can Expect Me To …


1. Provide lecture material online 1-2 days before each lecture.
2. Provide you with sample tests and practices questions online.
3. Answer your emails within 48 h.
4. Provide you with test grades within 1 week of the test.
5. Provide you with some times to meet with me to acquire more detailed answers to your
questions.

Class Schedule

LECTURE SCHEDULE FALL 2019

Date Lecture Topic Recommended reading


Alberts, 4th ed. Alberts, 5th ed.
Sept 4 1A Course Plan - -
Sept. 6 1B Introduction to cells 1-12 1-11
Sept. 9 2 Macromolecules 50-79 50-79
Sept. 11 3 Cell Cycle 603-613 607-619
Sept. 13 4 Mitosis + cytokinesis 618-633 624-639
Sept. 16 5 Nucleus structure 232-236, 495-497 237-242, 503-505
Sept. 18 6 DNA packaging 185-193 184-192
Sept. 20 7 Chromosome structure 179-185 178-184
Sept. 23 8 Transcription 262-280 268-287
Sept. 25 9 mRNA 224-242 228-245
Sept. 27 10 tRNAs, rRNAs, translation 224-253 228-259
Sept. 30 11 Non-coding RNAs 282-285 288-293
Oct. 2 12 Endomembrane system 487-492 495-500
Oct. 4 13 ER proteins & lipids 498-502 507-511
Oct. 7 - Midterm Exam 1 - -
Oct. 9 14 Golgi & vesicular traffic 503-515 511-523
Oct. 11 15 Lysosomes, endosomes 515-522 523-529
Oct. 14 - Thanksgiving – no classes - -
Oct. 16 16 Plasma membrane 359-381 365-387
Oct. 18 17 Membrane transport - I 383-389 389-395
Oct. 21 18 Membrane transport - II 389-401 395-408
Oct. 23 19 Cell signaling - I 526-538 533-545
Oct. 25 20 Cell signaling - II 539-551 545-557
Oct. 28 21 Cell signaling - III 551-563 557-570
Oct. 30 22 Cell energetics I 447-469 455-477
Nov. 1 23 Cell energetics II 469-483 478-492
Nov. 4 Midterm Exam 2
Nov. 6 24 Cytoskeleton – I 565-583 573-592
Nov. 8 25 Cytoskeleton – II 583-600 592-607
Nov. 11 - Remembrance Day – no class - -
Nov. 13 - Fall break – no class - -
Nov. 15 - Fall break – no class - -
Nov. 18 - No class - -
Nov. 20 26 Cell interactions - I 683-694 691-701
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Nov. 22 27 Cell interactions - II 694-702 701-709


Nov. 25 28 Cancer 712-725 718-729
Nov. 27 29 Apotosis 633-639 639-644
Nov. 29 30 Cell and tissue renewal 702-711 709-717
Dec. 2 29 Review

Course Evaluation Methods

Test 1 (lectures 1-11) 25%

Test 2 (lectures 12 to 23) 25%

Final exam

Lectures 24-30 25%

Overview of entire course 25%

Grading

90 + - A+
80 - 89 - A
74 - 79 - B+
68 - 73 - B
62 - 67 - C+
56 - 61 - C
50 - 55 - D
0 - 49 - F

Assignment Grading Times


You will be provided midterm test grades and answers to tests within 1 week of the test.

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