DR Lal Pathlabs: LPL - Lpl-Rohini (National Reference Lab) Sector - 18, Block - E Rohini Delhi 110085
DR Lal Pathlabs: LPL - Lpl-Rohini (National Reference Lab) Sector - 18, Block - E Rohini Delhi 110085
DR Lal Pathlabs: LPL - Lpl-Rohini (National Reference Lab) Sector - 18, Block - E Rohini Delhi 110085
s
ANTI NEUTROPHIL CYTOPLASMIC ANTIBODY ( ANCA)
(IFA)
ab
p-ANCA
c-ANCA
Titre
Note
L
th
1. Autoimmune reactivities are not by themselves diagnostic, but must be correlated with other
laboratory & clinical findings
2. Test conducted on Serum
Pa
Comments
Demonstration of ANCA is about 95% sensitive and 90% specific for Wegener’s granulomatosis and
Microscopic polyangiitis. Necrotising vasculitis are a group of disorders with varied clinical presentations
which include Wegener’s granulomatosis, Polyarteritis nodosa, Churg Strauss syndrome & Idiopathic
crescentic glomerulonephritis. ANCA positivity presents in two types of patterns, c -ANCA (Proteinase 3 /
al
--------------------------------------------------------------------
| PATTERN | ANTIGEN | CLINICAL ASSOCIATION |
rL
|---------------------------------------------------------------------|
| c-ANCA | PR3 | * Wegener’s granulomatosis (90%) |
| | | * Microscopic polyangiitis (50%) |
| | | * Churg Strauss syndrome (30%) |
| | | * Systemic sclerosis (20%) |
| | | * Rheumatoid arthritis (17%) |
| | | * Acute reactive arthritis (4%) |
| | | * Chronic reactive arthritis (2%) |
D
| | | * Crescentic glomerulonephritis |
|----------------|----------|-----------------------------------------|
| p-ANCA | MPO | * Necrotising crescentic |
| | | glomerulonephritis (80%) |
| | | * Polyarteritis nodosa (62%) |
| | | * Microscopic polyangiitis (50%) |
| | | * Rapidly progressive glomerulonephritis|
| | | (50%) |
| | | * Rheumatoid arthritis (47%) |
| | | * Churg Strauss syndrome (40%) |
|----------------|----------|-----------------------------------------|
|Atypical p-ANCA | MPO | * Ulcerative colitis (40%) |
PatientReportSCSuperPanel.SP_GENERAL_TEMPLATE01_SC (Version: 7)
*153672091*
Page 1 of 2
.
s
---------------------------------------------------------------------
ab
Dr Anil Arora Dr Parul Chopra Dr Sunanda
MD, Pathology MD, Laboratory Medicine MD, Pathology
HOD Hematology & Consultant Consultant
L
Immunohematology NRL - Dr Lal PathLabs Ltd NRL - Dr Lal PathLabs Ltd
NRL - Dr Lal PathLabs Ltd
Result/s to follow:
ANTI NEUTROPHIL CYTOPLASMIC ANTIBODY ( ANCA)
th
Pa
IMPORTANT INSTRUCTIONS
*Test results released pertain to the specimen submitted .*All test results are dependent on the quality of the sample received by the Laboratory .
*Laboratory investigations are only a tool to facilitate in arriving at a diagnosis and should be clinically correlated by the Referring Physician .*Sample
repeats are accepted on request of Referring Physician within 7 days post reporting.*Report delivery may be delayed due to unforeseen
circumstances. Inconvenience is regretted.*Certain tests may require further testing at additional cost for derivation of exact value. Kindly submit
request within 72 hours post reporting.*Test results may show interlaboratory variations .*The Courts/Forum at Delhi shall have exclusive
jurisdiction in all disputes/claims concerning the test(s) & or results of test(s).*Test results are not valid for medico legal purposes. * Contact
al
customer care Tel No. +91-11-39885050 for all queries related to test results.
(#) Sample drawn from outside source.
rL
D
PatientReportSCSuperPanel.SP_GENERAL_TEMPLATE01_SC (Version: 7)
*153672091*
Page 2 of 2