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Material Safety Data Sheet
Acetone MSDS
Section 1: Chemical Product and Company Identification
Product Name: Acetone
Catalog Codes: SLA3502, SLA1645, SLA3151, SLA3808
CAS#: 67-64-1
RTECS: AL3150000
TSCA: TSCA 8(b) inventory: Acetone
CI#: Not applicable.
Synonym: 2-propanone; Dimethyl Ketone;
Dimethylformaldehyde; Pyroacetic Acid
Chemical Name: Acetone
Chemical Formula: C3-H6-O
Contact Information:
Sciencelab.com, Inc.
14025 Smith Rd.
Houston, Texas 77396
US Sales: 1-800-901-7247
International Sales: 1-281-441-4400
Order Online: ScienceLab.com
CHEMTREC (24HR Emergency Telephone), call:
1-800-424-9300
International CHEMTREC, call: 1-703-527-3887
For non-emergency assistance, call: 1-281-441-4400
Section 2: Composition and Information on Ingredients
Composition:
Name CAS # % by Weight
Acetone 67-64-1 100
Toxicological Data on Ingredients: Acetone: ORAL (LD50): Acute: 5800 mg/kg [Rat]. 3000 mg/kg
[Mouse]. 5340 mg/kg
[Rabbit]. VAPOR (LC50): Acute: 50100 mg/m 8 hours [Rat]. 44000 mg/m 4 hours [Mouse].
Section 3: Hazards Identification
Potential Acute Health Effects:
Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly
hazardous in case of
skin contact (permeator).
Potential Chronic Health Effects:
CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH. MUTAGENIC
EFFECTS: Not available.
TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Classified Reproductive
system/toxin/female,
Reproductive system/toxin/male [SUSPECTED]. The substance is toxic to central nervous system (CNS).
The substance may
be toxic to kidneys, the reproductive system, liver, skin. Repeated or prolonged exposure to the
substance can produce target
organs damage.
Section 4: First Aid Measures
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Eye Contact:
Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15
minutes, keeping eyelids
open. Cold water may be used. Get medical attention.
Skin Contact:
In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient.
Remove contaminated
clothing and shoes. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before
reuse. Get medical
attention.
Serious Skin Contact:
Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek
medical attention.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical
attention if symptoms appear.
Serious Inhalation:
Evacuate the victim to a safe area as soon as possible. Loosen tight clothing such as a collar, tie, belt or
waistband. If
breathing is difficult, administer oxygen. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Seek medical
attention.
Ingestion:
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to
an unconscious
person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms
appear.
Serious Ingestion: Not available.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable.
Auto-Ignition Temperature: 465°C (869°F)
Flash Points: CLOSED CUP: -20°C (-4°F). OPEN CUP: -9°C (15.8°F) (Cleveland).
Flammable Limits: LOWER: 2.6% UPPER: 12.8%
Products of Combustion: These products are carbon oxides (CO, CO2).
Fire Hazards in Presence of Various Substances: Highly flammable in presence of open flames and
sparks, of heat.
Explosion Hazards in Presence of Various Substances:
Risks of explosion of the product in presence of mechanical impact: Not available. Slightly explosive in
presence of open
flames and sparks, of oxidizing materials, of acids.
Fire Fighting Media and Instructions:
Flammable liquid, soluble or dispersed in water. SMALL FIRE: Use DRY chemical powder. LARGE FIRE:
Use alcohol foam,
water spray or fog.
Special Remarks on Fire Hazards: Vapor may travel considerable distance to source of ignition and
flash back.
Special Remarks on Explosion Hazards:
Forms explosive mixtures with hydrogen peroxide, acetic acid, nitric acid, nitric acid + sulfuric acid,
chromic anydride, chromyl
chloride, nitrosyl chloride, hexachloromelamine, nitrosyl perchlorate, nitryl perchlorate, permonosulfuric
acid, thiodiglycol +
hydrogen peroxide, potassium ter-butoxide, sulfur dichloride, 1-methyl-1,3-butadiene, bromoform, carbon,
air, chloroform,
thitriazylperchlorate.
Section 6: Accidental Release Measures
Small Spill:
Dilute with water and mop up, or absorb with an inert dry material and place in an appropriate waste
disposal container.
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Large Spill:
Flammable liquid. Keep away from heat. Keep away from sources of ignition. Stop leak if without risk.
Absorb with DRY earth,
sand or other non-combustible material. Do not touch spilled material. Prevent entry into sewers,
basements or confined
areas; dike if needed. Be careful that the product is not present at a concentration level above TLV.
Check TLV on the MSDS
and with local authorities.
Section 7: Handling and Storage
Precautions:
Keep locked up.. Keep away from heat. Keep away from sources of ignition. Ground all equipment
containing material. Do
not ingest. Do not breathe gas/fumes/ vapor/spray. Wear suitable protective clothing. In case of
insufficient ventilation, wear
suitable respiratory equipment. If ingested, seek medical advice immediately and show the container or
the label. Avoid
contact with skin and eyes. Keep away from incompatibles such as oxidizing agents, reducing agents,
acids, alkalis.
Storage:
Store in a segregated and approved area (flammables area) . Keep container in a cool, well-ventilated
area. Keep container
tightly closed and sealed until ready for use. Keep away from direct sunlight and heat and avoid all
possible sources of ignition
(spark or flame).
Section 8: Exposure Controls/Personal Protection
Engineering Controls:
Provide exhaust ventilation or other engineering controls to keep the airborne concentrations of vapors
below their respective
threshold limit value. Ensure that eyewash stations and safety showers are proximal to the work-station
location.
Personal Protection:
Splash goggles. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent.
Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Vapor respirator. Boots. Gloves. A self contained breathing apparatus should be
used to avoid
inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist
BEFORE handling this
product.
Exposure Limits:
TWA: 500 STEL: 750 (ppm) from ACGIH (TLV) [United States] TWA: 750 STEL: 1000 (ppm) from OSHA
(PEL) [United
States] TWA: 500 STEL: 1000 [Austalia] TWA: 1185 STEL: 2375 (mg/m3) [Australia] TWA: 750 STEL:
1500 (ppm) [United
Kingdom (UK)] TWA: 1810 STEL: 3620 (mg/m3) [United Kingdom (UK)] TWA: 1800 STEL: 2400 from
OSHA (PEL) [United
States]Consult local authorities for acceptable exposure limits.
Section 9: Physical and Chemical Properties
Physical state and appearance: Liquid.
Odor: Fruity. Mint-like. Fragrant. Ethereal
Taste: Pungent, Sweetish
Molecular Weight: 58.08 g/mole
Color: Colorless. Clear
pH (1% soln/water): Not available.
Boiling Point: 56.2°C (133.2°F)
Melting Point: -95.35 (-139.6°F)
Critical Temperature: 235°C (455°F)
Specific Gravity: 0.79 (Water = 1)
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Vapor Pressure: 24 kPa (@ 20°C)
Vapor Density: 2 (Air = 1)
Volatility: Not available.
Odor Threshold: 62 ppm
Water/Oil Dist. Coeff.: The product is more soluble in water; log(oil/water) = -0.2
Ionicity (in Water): Not available.
Dispersion Properties: See solubility in water.
Solubility: Easily soluble in cold water, hot water.
Section 10: Stability and Reactivity Data
Stability: The product is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, ignition sources, exposure to moisture, air, or water,
incompatible materials.
Incompatibility with various substances: Reactive with oxidizing agents, reducing agents, acids,
alkalis.
Corrosivity: Non-corrosive in presence of glass.
Special Remarks on Reactivity: Not available.
Special Remarks on Corrosivity: Not available.
Polymerization: Will not occur.
Section 11: Toxicological Information
Routes of Entry: Absorbed through skin. Dermal contact. Eye contact. Inhalation.
Toxicity to Animals:
WARNING: THE LC50 VALUES HEREUNDER ARE ESTIMATED ON THE BASIS OF A 4-HOUR
EXPOSURE. Acute oral
toxicity (LD50): 3000 mg/kg [Mouse]. Acute toxicity of the vapor (LC50): 44000 mg/m3 4 hours [Mouse].
Chronic Effects on Humans:
CARCINOGENIC EFFECTS: A4 (Not classifiable for human or animal.) by ACGIH. DEVELOPMENTAL
TOXICITY: Classified
Reproductive system/toxin/female, Reproductive system/toxin/male [SUSPECTED]. Causes damage to
the following organs:
central nervous system (CNS). May cause damage to the following organs: kidneys, the reproductive
system, liver, skin.
Other Toxic Effects on Humans:
Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin
contact (permeator).
Special Remarks on Toxicity to Animals: Not available.
Special Remarks on Chronic Effects on Humans:
May affect genetic material (mutagenicity) based on studies with yeast (S. cerevisiae), bacteria, and
hamster fibroblast cells.
May cause reproductive effects (fertility) based upon animal studies. May contain trace amounts of
benzene and formaldehyde
which may cancer and birth defects. Human: passes the placental barrier.
Special Remarks on other Toxic Effects on Humans:
Acute Potential Health Effects: Skin: May cause skin irritation. May be harmful if absorbed through the
skin. Eyes: Causes
eye irritation, characterized by a burning sensation, redness, tearing, inflammation, and possible corneal
injury. Inhalation:
Inhalation at high concentrations affects the sense organs, brain and causes respiratory tract irritation. It
also may affect the
Central Nervous System (behavior) characterized by dizzness, drowsiness, confusion, headache, muscle
weakeness, and
possibly motor incoordination, speech abnormalities, narcotic effects and coma. Inhalation may also affect
the gastrointestinal
tract (nausea, vomiting). Ingestion: May cause irritation of the digestive (gastrointestinal) tract (nausea,
vomiting). It may also
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affect the Central Nevous System (behavior), characterized by depression, fatigue, excitement, stupor,
coma, headache,
altered sleep time, ataxia, tremors as well at the blood, liver, and urinary system (kidney, bladder, ureter)
and endocrine
system. May also have musculoskeletal effects. Chronic Potential Health Effects: Skin: May cause
dermatitis. Eyes: Eye
irritation.
Section 12: Ecological Information
Ecotoxicity:
Ecotoxicity in water (LC50): 5540 mg/l 96 hours [Trout]. 8300 mg/l 96 hours [Bluegill]. 7500 mg/l 96 hours
[Fatthead Minnow].
0.1 ppm any hours [Water flea].
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short term degradation products are not likely. However, long term degradation
products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not
toxic.
Special Remarks on the Products of Biodegradation: Not available.
Section 13: Disposal Considerations
Waste Disposal:
Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT Classification: CLASS 3: Flammable liquid.
Identification: : Acetone UNNA: 1090 PG: II
Special Provisions for Transport: Not available.
Section 15: Other Regulatory Information
Federal and State Regulations:
California prop. 65: This product contains the following ingredients for which the State of California has
found to cause
reproductive harm (male) which would require a warning under the statute: Benzene California prop. 65:
This product contains
the following ingredients for which the State of California has found to cause birth defects which would
require a warning under
the statute: Benzene California prop. 65: This product contains the following ingredients for which the
State of California has
found to cause cancer which would require a warning under the statute: Benzene, Formaldehyde
Connecticut hazardous
material survey.: Acetone Illinois toxic substances disclosure to employee act: Acetone Illinois chemical
safety act: Acetone
New York release reporting list: Acetone Rhode Island RTK hazardous substances: Acetone
Pennsylvania RTK: Acetone
Florida: Acetone Minnesota: Acetone Massachusetts RTK: Acetone Massachusetts spill list: Acetone New
Jersey: Acetone
New Jersey spill list: Acetone Louisiana spill reporting: Acetone California List of Hazardous Substances
(8 CCR 339):
Acetone TSCA 8(b) inventory: Acetone TSCA 4(a) final test rules: Acetone TSCA 8(a) IUR: Acetone
Other Regulations:
OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). EINECS: This
product is on the
European Inventory of Existing Commercial Chemical Substances.
Other Classifications:
WHMIS (Canada):
CLASS B-2: Flammable liquid with a flash point lower than 37.8°C (100°F). CLASS D-2B: Material
causing other toxic effects
(TOXIC).
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DSCL (EEC):
R11- Highly flammable. R36- Irritating to eyes. S9- Keep container in a well-ventilated place. S16- Keep
away from sources of
ignition - No smoking. S26- In case of contact with eyes, rinse immediately with plenty of water and seek
medical advice.
HMIS (U.S.A.):
Health Hazard: 2
Fire Hazard: 3
Reactivity: 0
Personal Protection: h
National Fire Protection Association (U.S.A.):
Health: 1
Flammability: 3
Reactivity: 0
Specific hazard:
Protective Equipment:
Gloves. Lab coat. Vapor respirator. Be sure to use an approved/certified respirator or equivalent. Wear
appropriate respirator
when ventilation is inadequate. Splash goggles.
Section 16: Other Information
References:
-Material safety data sheet issued by: la Commission de la Santé et de la Sécurité du Travail du
Québec. -The Sigma-
Aldrich Library of Chemical Safety Data, Edition II. -Hawley, G.G.. The Condensed Chemical Dictionary,
11e ed., New York
N.Y., Van Nostrand Reinold, 1987. LOLI, RTECS, HSDB databases. Other MSDSs
Other Special Considerations: Not available.
Created: 10/10/2005 08:13 PM
Last Updated: 05/21/2013 12:00 PM
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