Breast Reconstruction, Almomin
Breast Reconstruction, Almomin
Breast Reconstruction, Almomin
Breast Reconstruction
Requires a multidisciplinary approach to include: General Sx, plastic Sx, medical oncologist &
radiation oncologist social worker
The patients’ oncologic status must not be compromised by a breast reconstructive plan (future
radiation)
Consider future oncologic procedures (contralateral prophylactic mastectomy)
History:
1. Breast/Oncology
a) Ipsilateral Breast
• Tumor details
1. Histology
2. Grade
3. Stage: local, regional, distant mets. TNM
b) Contralateral Breast
• Hx breast biopsy, benign breast disease, surgery
• Last mammogram/MRI
• Height, weight, bra size
2. EXPECTATIONS
• Determine patient’s motivation, goals, desires
• Realistic expectations
• PMH (CVS, Resp, DM, HTN) – risk factors for DVT, wound healing
Hx of coagulopathy ,
o Hx of abortions and miscarriages
may suggest Antiphospholipid synd.
Hx of renal failure may affect micro
• Smoking
• Meds & allergies
• PSHxprevious Sx in donor sites
– Abdominal (C-Section, open chole, laparoscopy)
– ALND (implications for recipient vessels)also LD
• Future pregnancies? (Implications if considering pedicled TRAM)
Physical exam
1. BREAST EXAMINATION
a) Ipsilateral Breast
1. Mastectomy defect - incisions/ scars
2. Pectoralis muscle (presence/function?)
3. Axilla – scars, LNs
4. Skin quality/viability
• Thickness
• Elastic properties
• Radiation changes
• Adhesions to chest wall
b) Contralateral Breast
measurements:
• Breast dimensions: base width, height N→IMF, N→Sternum, N→SS notch, N
projection/diameter, A diameter
• Volume, IMF, NAC position
• Shape, ptosis, skin brassiere
• Full breast exam & LNs
investigators
2. GENERAL PHYSICAL EXAMINATION
body systems
• CVS, resp, etc.
• Body habitus
height, weight, BMI
Can be: two stage (initiated by expanders) or single stage (direct to implant)
If an expander was used: it will have good breast mound with no tight skin envelope
If flap was used: skin paddle is small and circular, only NAC will be replace by the flap skin
Advantages:
Disadvantages:
Advantages:
allows patients who do not require postmastectomy radiation therapy to receive the benefits of with
aesthetic outcomes similar to those of immediate reconstruction.
Patients who do require radiation receive a skin-preserving delayed reconstruction,while avoiding the
problems that can be associated with radiation delivery after an immediate breast reconstruction
*The trend now is for offering postmastectomy radiotherapy to patients with T1/T2 tumors with fewer than
four positive axillary lymph nodes
Remember :
Pt who needs postmastectomy radiation:
o do delayed reconstruction
Pt who don’t need postmastectomy radiation:
o do immediate reconstruction
Uncertain about the need of postmastectomy radiation:
o Dealyed(recon)-Immediate(pattern and look) reconstruction
o Put an expander in and inflate it like immediate to save skin & wait for path
results:
o XRT not needed: then proceed with recon (either an implant or flap)
o XRT needed: deflate during XRT, then inflate once XRT finished then proceed
to final recon as above.
o By doing this you saved the breast native skin envelope and you protected your
final recon flap from radiation.
Reconstructive ladder
Type of mastectomy
Condition of skin envelope
Time of reconstruction
Condition of contralateral breast
Options:
Non-surgical options:
External prosthesis
Camouflage (NAC(
procedure to normal breast only to reduce asymmetry
Surgical options:
A. Alloplastic:
1 stage: Breast Implant
2 stages: Tissue expander Breast Implant
B. Autogenic:
Pedicled flap
Free flap
Allopalstic reconstruction:
Over the years, implant technology and surgical techniques have evolved, resulting in improvement in the
quality of the reconstructed breast
Immediate vs delayed
1 stage vs 2 stages
Advantages Disadvantages
• Technically easier • Intolerant of radiotherapy
• Less OR time • Less natural result (implant rippling)
• Rapid recovery / less hospitalization • Difficult to match a large, ptotic breast
• Rapid return to work • Expander / implant complications :
• No donor site morbidity • At least a 2 stage procedure
• No new scars • Longer time to achieve final goal
• Versatile (size easily adjusted for symmetry) repeated visits for expansion
Allopalstic reconstruction
Indications Contraindications
Adequate skin envelope (1 stage) Patient refuses alloplastic materials
Skin envelope not adequate (2 stages) Prior or Anticipated Radiotherapy
Patient unwilling / unable to tolerate (relative)
autogenous reconstruction Immediate recon: Poor mastectomy flap
No available donor sites quality intra-op or inadequate envelop
Patient unwilling to accommodate repeated
visits for expansion
Complications:
Early Late
Hematoma Rupture / leak 8%
seroma, 4% Capsular contracture /Calcification 25%
infection 4% Asymmetry: size, shape, position 12%
Deflation 6% Rippling 23 %
Implant /expander exposure 3% Asymmetry 33%
Skin or tissue necrosis 4 % Reoperation 39%
Expander malfunction
o Leakage
o Port inaccessible
Surgical tips:
Choosing the appropriate expander is based on several factors, including breast volume, breast
dimensions (height, width, and projection), breast shape, and the patient's body habitus.
o In general, an anatomically designed, textured surface, integrated valve tissue expander is
preferred
The expander should be placed in a complete submuscular pocket
o Achieved by elevating the medial border of the serratus anterior muscle/fascia and elevating
the pectoralis major from lateral to medial and bringing both the subserratus and subpectoral
pocket into communication at the level of or slightly below the inframammary fold
Disadvantages of complete submuscular pocket "
o attenuation of pectoralis major
o underexpansion of the lower pole
o pain associated with elevation of the serratus muscle/fascia.
An alternative to using the serratus anterior muscle is to use acellular dermal matrix
o This can be approached in different categories;
§ Delayed-immediate reconstruction.
§ Direct to implant reconstruction.
§ DELAYED-IMMEDIATE RECONSTRUCTION.
o Most alloplastic reconstructions continue to be performed in 2 stages, with a tissue expander followed by
an implant.
o Surgical approaches discriped as follow:
§ Sub-musclo-fascia coverage:
• Create subpectoral pocket- pectoralis major muscle is raised from inferior inserion, rectus fascia can be
raised inferiorly; and laterally, cover with serratus anterior flap.
• Position TE as close to IMF as possible (or below IMF – need to recreate later if you do this) – to
preferentially expand lower pole.
• Ensure port anterior.
• Fix the expander the underlying facia to prevent lateral displacment.
• Inflate (or partially inflate) the TE if pocket dimensions allow then cover the TE with the raised muscles.
• Place drains.
§ Sub-Musclo-ADM coverage:
• This method utilizes ADM insteat of native tissue to creat the inferor coverage of the expander. With the
reminder of the procedure advanced the same.
• It add to the cost of reconstruction.
§ This general use of these different approaches is to help releiving the native breast flaps from the
tension of the expander/implant.
ADM Advantages:
quicker expansion,
decreased pain caused by dissecting the serratus for submuscular coverage,
improved cosmesis provide inferolateral support during expansion
ADM Disadvantages:
Higher incidence of overall complications, seroma (7.2%) and reconstructive failure (5.9%) mostly
due to infection
• Complications of ADM:
Indications Contraindications
• Previous Radiotherapy (relative) • Poor general health precludes lengthy surgical
• Patient preference / refusal of alloplastic procedure
materials • Refusal of donor site morbidity / scars
Advantages Disadvantages
• More natural shape • Technically more demanding - experience required for
• Permanent reconstruction free flaps
• Single stage (excluding NAC +/- revisions) • Longer OR, hospitalization, recovery
• Tolerate irradiation better than alloplastic • Donor site morbidity
reconstructions • Systemic complications eg. DVT, PE
• Versatile (variable size / shape of soft tissue
available)
• No complications of expander or implants
Pedicled flap
TRAM flap
First described for breast reconstruction by Hartrampf in 1982
The rectus abdominis muscle:
Blood Supply:
Mathes and Nahai Type III muscle
Deep superior epigastric artery
• Source: IMA
• Length: 2-5cm, Diameter: 1.8mm
• Location: deep to rectus, medial to mid 1/3
Deep inferior epigastric artery
• Source: EIA
• Length: 5cm, Diameter: 2.5mm
• Location: deep to rectus, enters from lateral in mid 1/3 ~ 4 cm above pubic tubercle @
arcuate line
Tram
Two rows of perforators:
– Medial perforators: 0.5-1cm lateral to the midline Middle?
– Lateral perforators: 1-2cm medial to the linea semilunaris
Skin island:
– Size: 40 X 14 Cm extending vertically from the umbilicus (or 1-3 cm superior to it) to pubic hair line
(or 1-5 cm superior to it) depends on the skin laxity, & transversely between the anterior iliac spines.
– Pedicled TRAM skin island receives blood flow by means of para- and infra-umbilical perforators of
the DIEA, which fill in a retrograde fashion from the SEA by means of reduced-caliber choke
vessels.
Scheflan and Dinner assigned the original four zones of perfusion to the unipedicled TRAM flap .
Some authors feel that zones II and III should be switched
o e.g Holm / Ninkovic (1998) – described for free TRAM
Indications Contraindications
Hartrampf’s group suggests that a single pedicle can reliably carry 60% of the calculated volume of
the abdominal ellipse
Ipsilateral pedicle:
Disadvantages:
Single pedicled TRAM augmented with additional blood flow and venous drainage by microvascular
anastomosis of either SIEA/V or DIEA/V to thoracodorsal A/V in the axilla
D.Turbocharged TRAM:
Single pedicle TRAM with transmidline retrograde microvascular loop anastomosis of DIEA/V
Allows increased blood flow to remote areas of the flap (zone IV) + augmented venous outflow
Abdominal wall closure similar to single pedicle
Bilateral ligation of both SIEA/V + DIEA/V 2-3 weeks prior to TRAM elevation
Performed through bilateral inguinal incisions within the outline of the proposed TRAM flap design
Results in overall increase in arterial pressure (from 13 to 40mmHg) with decrease in venous
congestion
Decreased fat necrosis in high risk patients
Abdominal wall repair:
A radical harvest of the anterior rectus sheath & rectus muscle is not necessary:
Elevate the flap with that portion of the rectus muscle & sheath which includes the important
perforators & superior epigastric vessels
Techniques to accommodate primary repair of the abdominal wall:
o Leave a 1 cm lateral &medial strip of rectus muscle & sheath
o Narrow tongue of rectus sheath and small triangle of rectus muscle below arcuate line.
o Reinforcement of repair with Mesh is an option
Underlay
Early Late
Recipient site: Recipient site:
o Partial flap los)%61) o Fat necrosis (up to 30%)
o Total flap loss )%6( o Asymmetry, irregularity
o Necrosis of mastectomy flaps
o Hematoma, Seroma, infection Donor Site:
; – Bulges /laxity (7.8%) (abdominal,
Donor Site epigastric, IMF)
o Necrosis of abdominal flap – Hernia
o Umbilical necrosis – Abdominal weakness
– Umbilical malposition / distortion
Medical / systemic: – Stitch abscess
o Blood loss / anemia, DVT / PE – Mesh infection / extrusion
– Palpable sutures / mesh
– Abdominal wall hypoesthesia
– Contour irregularities, dog ears, etc
Latissimus dorsi flap breast reconstruction:
Anatomy :
Indications Contraindications
Small to moderate sized breast (in conjunction Prior lateral thoracotomy with division of the
with implant latismus muscle
Other flap sources not available or not optimal Prior division of the thoracodorsal trunk (relative if
brancehs from serratus anterior is intact)
Skin island for nipple-areola reconstruction
Athletic woman requiring using of latismus muscle
Muscle implant coverage is desirable ( relative)
Secondary breast reconstruction Smoker ( relative)
Salvage flap –coverage for imminent implant
exposure or failed TRAM
Reconstruction of partial mastectomy
Reconstruction of poland syndrome
Skin Design:
Modification :
A.Added volume :
The looser and less-compact deep layer of fat below the fascia is harvested with the muscle to
augment the volume of the flap.
This fatty layer can be harvested beyond the borders of the muscle, particularly along the
extended
superior and inferior margins of the flap.
Can increase seroma formation rate
D. FLEUR-DE-LIS MODIFICATION
Similar volume as horizontal ellipse
More skin available
More projection of breast mound
Larger donor site scar
Advantages & Disadvantages:
Advantages Disadvantages
Very reliable Intraoperative positioning more difficult
Rapid recovery Difficult to perform bilateral reconstruction
Restore anterior axillary fold in single stage
Can be used in radiated breasts Minimal bulk – generally must be used in
Minimal donor site morbidity combination with prosthesis
Complication:
Seroma
o Most common complication (reported as high as 21- 79%)
Drain placement for enough time, Quilting sutures and Fibrin glue can decrease
seroma formation rate (to 5 %)
Wound infection and dehiscence
Shoulder weakness
Thoracolumbar hernia
Winging scapula
long thoracic
Omental
Thoracoepigastric
FREE FLAPS:
Recipient vessels
3rd Intercostal:
Most common: IMA, Thoracodorsal
Other potential :scapular circumflex vessels, the thoracoacromial vessels, and the axillary artery
and vein
Muscle Flaps:
Indications contraindications
Abdominal scarring that precludes Lower abdominal surgery that has
pedicled TRAM violated the inferior epigastric vessels or
Procedures that have divided the the perforators
superior epigastrics Inguinal hernia repair,
Factors that increase risk of fat Medically unfit patient
necrosis (relative) Recipient vessel unavailable
Obesity / Smokers Lack of microsurgery expertise
High percentage of available flap Previous abdominoplasty
territory is required
Advantages – Disadvantages:
Advantages Disadvantages
Better blood supply, thus less fat necrosis Potential for total flap loss
and less partial flap loss Potential for urgent return to the OR
Less muscle harvest, less morbidity for salvage anastomatic failure
No epigastric tunnel thus no epigastric bulge
Complications
Fat necrosis Partial flap loss Total flap loss Bulge/Hernia
Free TRAM 2-16% 0-2% 0-4% 3-10%
Pedicled TRAM 5-30% 5-15% 0-3% 1-15%
DIEP 6-18% 0-9% 0-4% 0-10%
It’s a MS-3 (free TRAM flap with complete preservation of rectus abdominus muscle)
Evolved from the TRAM flap 1st by Koshema and Soida in 1989
Based on the deep inferior epigastric artery which is a branch of External iliac artery, deep to the
inguinal ligament.
It has a variable branching pattern within the muscle,
o 54% dividing into a medial branch and a dominant lateral branch
o 28% have a central course with multiple small branches
o 18 % has a dominant medial branch
There are 2-8 perforators greater than 0.5 mm in diameter that pierce each side of the anterior rectus
fascia in the paraumbilical region between 2 cm cranial and 6 cm caudal to the umbilicus and
between 1 to 6 cm lateral to the umbilicus
lateral perforators tend to have a more direct perpendicular course through the muscle, whereas
medial perforators may have a long, complicated, and oblique intramuscular course with numerous
subsidiary muscular branches along the way
a more medial perforator may be more likely to supply a greater portion of the flap on the
contralateral side of the abdomen
Relies on venous drainage through small perforating veins. In some patients, the superficial venous
drainage system may be dominant, so it should be preserved as an alternate source of venous
drainage
Advantages disadvantages
Flap complications
Hernia 1% 16%
Hematoma 7% 6.2 %
Abdominal complications 6% 17 %
Hernia 1.5 % 2%
Advantages Disadvantages
IGAP flap is based on a suitable perforator from the inferior gluteal artery& vein
Plus or minus a segment of upper gluteus maximus muscle (musculocutaneonus flap)
Longer pedicle than SGAP
I-GAP is Easier to do than S-GAP but can expose sciatic nerve during dissection.
More bulky tissue, firm consistency fat IGA runs with sciatic
Donor scar hidden in inferior gluteal crease nerve
Flap dimensions 8X18 cm centered over the gluteal crease lateral to ischium,
pedicle length 8-11 cm
Potential for neurosensory flap (S1-2)
Flap design:
Horizontal ellipse on skin 4cm above inferior gluteal crease, width =10cm, lateral to the
ischium
5- TRANSVERSE UPPER GRACILIS (TUG) FLAP :
MN classification: Type II
Dominant Pedicle: medial femoral circumflex artery 1-2 mm, & 2 VC
Minor pedicle: superficial femoral branches
Nerve: obturator nerve
Pedicle length – 6-8 cm
Flap Design :
semilunar skin paddle centered over the longitudinal axis of the gracilis muscle in the inner thigh
The superior aspect of the flap is marked approximately one fingerbreadth below the groin crease
anteriorly and centrally, but extends into the gluteal crease at the most posterior aspect.
The anteroposterior length has been made up to 25 cm.
The width of the flap is judged by pinching the inner thigh tissue with the thighs in adduction (up to
12 cm)
Advantages :
Disadvantages :
Small volume
Skin medial/lateral to gracilis can be unreliable
Donor site morbidity – retraction of labia, scars, wound healing difficulties
Lymphedema
6-SUPERFICIAL INFERIOR EPIGASTRIC ARTERY PERFORATOR (SIEA) FLAP:
In order to achieve symmetry it is important to have a definitive goal in mind for the opposite breast during
the planning stages of the reconstruction
No alteration
Mastopexy
Breast reduction
Breast augmentation
Mastopexy-augment
Prophylactic mastectomy
Volume contouring
Liposuction/Lipofilling
excision of tissue
Skin envelope modifications
Removal of fat necrosis
Inframammary fold creation / repositioning
Scar Revisions
NIPPLE – AREOLA RECONSTRUCTION
The nipple contains ductal tissue that might contain cancer cells, but the areola is a skin
that might be resected to achieve free skin margin.
The NAC is ideally located at the most prominent part of the breast or above the level of
projected inframmamry crease
Goals:
Adequate position
sensation
Ensure that a stable, viable breast mound has been achieved prior to NAC Reconstruction
options: مهم
ADM
افضل خيار اذا ابي بروجكشن عالي
factors affecting
projection:
-type of flap
-width of flap
-avoid direct pressure on
nipple by dressing
-avoid tension on closure
..
immediately post op,
projection should be
twice desired final
-most loss of nipple projection
projection occurs in
first 2 months post op
-most impt factor: width
of flap
-skate: best projection
Skate flap:
Draw a line across the width of the areola which is the base of the flap
Base is away from the mastectomy scar and can be oriented vertical or transverse
good projection, not good if very thin skin over implant ,requires skin graft
Star flap:
A star pattern with 3 wings is drawn and can be based superior or inferior
no STSG required, Provides low-moderate projection
reconstruction of nipples
with very little (,5 mm) purse-string suture
Bell flap: projection
The unique design also incorporates a purse-string areola closure that provides slight areolar projection