Biology O-Level Notes

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BIOLOGY

Secondary Notes
O-LEVEL

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Soma bure Notes za O-Level hadi A-level

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TABLE OF CONTENTS

FORM ONE ………………………………………………………………………………..… 2

FORM TWO …………………………………………………………………….……..…… 12

FORM THREE ……………………………………………………………...…………..…... 35

FORM FOUR …………………………………………………………..…………………… 60

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Tembelea Msomi Bora upakue:
1. Notes za O-Level hadi A-Level

2. Solving za Mitihani (Review)

3. Mitihani ya Nursery, Primary na Secondary

4. Vitabu vya Primary hadi Secondary

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Biology- is the scientific study of life and living things

1: WASTE DISPOSAL
Pollutant - A substance present in a large enough quantity in the environment to be harmful to living
things
Recycling - The reuse of waste paper, metal, glass or other raw materials to conserve raw materials and
reduce pollution
Proper ways of disposing of waste -
Recovery, recycling, reduction, safe disposal
Recovery - Turning materials considered to be waste into something useful (ex. changing cow dung into
biogas)
Recycling - Bringing items to a secondary processing place where they are turned into other useful items
Reduction of Use - Reducing waste production by buying more durable, less toxic materials which use
less packaging
Safe Waste Disposal - Disposal of waste in a safe area or a landfill which is designed to hold waste
Safe Disposal Site - A site to dump waste which has been approved by the appropriate authorities in
Government

2: HEALTH
Immunity - The body’s ability to prevent an infection by having antibodies which fight against pathogens.
It is the ability of the body to resist diseases
Types of Immunity -
Naturally Acquired Immunity - A type of immunity developed by an organism’s body against
particular disease after exposure to the microorganism causing the disease
Artificially Acquired Immunity - A type of immunity in which an organism develops after being
vaccinated against an infection
Diseases against which children are immunized -
Polio, tuberculosis, diphtheria, measles, tetanus, pertusis (whooping cough), small pox, hepatitis
B, mumps

INFECTIONS AND DISEASES


Disease - An abnormal condition affecting the body of an organism
Endemic - Diseases which occur in one region only
Epidemic - Occurs when a diseases rapidly spreads through a large portion of a population
Pandemic - Occurs when an epidemic spreads across whole continents (ex AIDS)
Non-communicable Diseases - Diseases which are not infectious and are caused by factors like
malnutrition, inheritance, environment or hormones

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Examples of Non-communicable Diseases -


Sickle-cell anemia, lung cancer, diabetes, marasmus, kwashiorkor, scurvy, rickets, night
blindness, anemia

CAUSES, TRANSMISSION AND PREVENTION OF VARIOUS DISEASES -


MENINGITIS -
Causes - Microorganisms such as viruses, bacteria or fungi
Transmission - Direct contact with an affected individual or sharing of utensils
Symptoms - Swelling of the spinal and brain tissues
Prevention -
Vaccination
avoiding contact with infected individuals
use of preventive antibiotics
CHOLERA -
Causes - Bacteria called V. cholera found in water contaminated by feces from diseased carriers
Transmission - Through direct contamination of food or water by feces as a result of poor
hygiene
Symptoms -
Watery diarrhea
vomiting excessively
body weakness
fast pulse
loss of body weight
severe dehydration
tightening of muscles with cramps in hands and feet
Prevention -
Provision of clean and safe drinking water
heating food to high temperatures
keeping food/drinks covered
washing hands before eating
wash fruits/vegetables in safe water
proper sewage treatment and sanitation
improve personal and public hygiene
proper use of toilets
treating carriers of the disease to break the cycle
vaccination
Effects -
Severe diarrhea
damage to cell lining in intestine
delay in treatment can lead to death
MALARIA -

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Causes - Four parasites of the genus plasmodium (P malaria, P vivax, P ovale, P falciparum)
Transmission - Mosquitoes carry the plasmodium and infect humans by biting them
Symptoms -
High fever
dizziness
joint pain
sometimes vomiting
Prevention -
Attacking the source -
Drain unwanted ponds and pools
clear bushes and grass around a living environment
introduction of animals which eat mosquitoes
do not leave standing water
Interrupting Transmission -
Sleep under mosquito nets
use mosquito repellents and insecticides
burn mosquito coils to expel mosquitoes
Protect the Host -
Effective treatment when sick, malaria prophylaxis like chloroquine or
mephaquine
BILHARZIAS (Schistomiasis) -
Occurs in the abdomen or urinary tract
Causes - Caused by flatworms in the large and small intestine or urinary bladder
Transmission - The worm lives in a snail until it produces larva which swim in a body of water
and infect a human who is swimming there. They enter the water when a person with the
worm urinates in the water
Symptoms -
Pain and blood during urination due to the ulceration of the bladder and urethra,
nausea
loss of appetite
blood in feces
Prevention -
Killing host snails
introduction of ducks to eat snails
destroy breeding places of snails
treat patients so the life cycle is broken
educating people on the importance of latrines and boiling water
RICKETS -
Causes -
Lack of vitamin D, common in children without access to vitamin D

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Symptoms -
Bone tenderness
dental problems
skeletal deformity
Prevention -
Dietary supplements or more exposure to sunlight
SHOCK -
Is a sudden loss of consciousness arising from the failure of blood to circulate properly to all
body parts, especially the brain
Causes -
Emotional stress
low blood pressure
illness (malaria or anemia)
severe injury/blood loss
SYPHILIS -
Transmission - Sexually transmitted disease
Effects -
Death of an unborn baby if syphilis is transmitted to the baby
deafness of the baby
a person with syphilis can become blind or have heart disease
TYPHOID -
Causes - Ingestion of contaminated water or food by the feces of an infected person which
contain the salmonella bacteria
Symptoms -
High fever
sweating
diarrhea
inflammation of the GI tract
Prevention -
Sanitation and hygiene to prevent people from eating or drinking contaminated food or
water
HEART BURN -
A burning sensation in the chest caused by the regurgitation of gastric acid
Prevention of hearth burn -
Use of medicine to stop the regurgitation of gastric acid

Diseases caused by Bacteria -


Tuberculosis pneumonia syphilis
cholera gonorrhea throat infection

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diphtheria salmonella (food poisoning)


tetanus (lockjaw) meningitis
leprosy botulism ringworm

Diseases caused by Viruses -


AIDS measles
rubella influenza (the flu)
polio smallpox herpes mumps
Diseases caused by Parasites -
Malaria bilharzias
dysentery sleeping sickness

Diseases caused by Fungi -


Ringworm athlete’s foot thrush

Diseases transmitted by Polluted Water -


Cholera typhoid fever
schistosomiasis bacterial dysentery
amoebiasis (amoebic dysentery)

Diseases associated with Uncooked Food -


All types of bacterial, viral and worm infections

Cause of fainting - Sudden drop of blood pressure


Anorexia Nervosa - An obsessive desire to lose weight by eating very little food
Emphysema - Thinning of the lung tissue leading to the rupture of alveoli. Caused by smoking
Hypothermia - The cooling of the body until it is well below the normal 37°C
Meningitis - Inflammatory condition
Pathology - The scientific study of the effects on the body of disease
Vaccine - A suspension of dead, inactivated or harmless germs which when introduced to the blood
stream stimulates the production of antibodies and makes the body immune to attack from that
disease

HIV/AIDS and STDs


HIV - The virus which causes AIDS. It is transmitted by unsafe sex with an infected person, blood
transfusion, sharing of needles by drug users
AIDS (Acquired Immunodeficiency Syndrome) - A disease caused by a virus which damages the
immune
system so that humans are unable to fight disease
Ways to contract HIV -
Unsafe sex

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sharing of needles
breast milk
transmission by mother to baby at birth
Ways not to contract HIV -
Hugging touching
kissing mosquitoes
swimming with an infected person
How to care for those with HIV/AIDS -
Clinical Care -
Preventative care with antibiotics
insecticide treated nets
improving quality of drinking water
good hygiene practices
nutritional counseling
Social Care -
Avoiding segregation of HIV victims,
provide counseling,
family support groups
encouraging them not to spread HIV
encourage physical exercise
Ways to care for HIV/AIDS patients -
Avoiding stigmatization
provide balanced diet
support them mentally/physically/socially/financially
love them
clean their living environment
send them to health centers for treatment and ARVs

3. CELL STRUCTURE AND ORGANIZATION


Main parts of a cell -
Cell Membrane - Made of living material. Its function is to enclose and protect the inner parts of
the cell by selectively allowing certain substances to pass through while preventing
others making it selectively permeable
Nucleus - Is a spherical or oval body which is seen when cells are stained. It is composed of a
fluid called nucleoplasm and is surrounded by a membrane called the nucleo-membrane.
The nucleus controls the life processes of a of a cell such as growth, respiration and
synthesis of materials. The nucleus also controls the hereditary characteristics of an
organism
Cell Wall - Is made up of non living material called cellulose. The major function is to give shape
and support to the cell. The cell wall is freely permeable to water and gases
Cytoplasm - Is composed of a mixture of chemicals and water whose role is to store food

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Chloroplasts (Plants Only) - Small bodies within cytoplasm containing chlorophyll. It is the
where photosynthesis occurs producing carbohydrates for the plant
Cell Vacuole - Cavity within cytoplasm filled with sap and enclosed by a membrane called
vacuolar membrane. The accumulation of water in the vacuole creates pressure to exert
on the cytoplasm and the cell wall to make plant cells firm and strong

Examples of cells in the Human Body -


The longest cell - Nerve cell (neuron)
A motile cell - Sperm
A cell with strong contractile ability - Muscle cell

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A cell which moves and feeds like an amoeba - White blood cell
Cell - A unit of living matter consisting of a nucleus, cytoplasm and a cell membrane
Cell Membrane - The semi-permeable membrane which forms the outer surface of all cells
Cell Wall - Outer membrane surrounding a cell which is made of cellulose and controls the flow of
particles in and out of the cell through osmosis
Cytoplasm - All of the contents of a cell except its nucleus
Internal Environment - The tissue fluid that bathes every cell of the body and supplies all of their food
and oxygen requirements
Mitochondria - Rod-shaped organelles in the cytoplasm of cells which is concerned with respiration
Nucleus - Part of the cell which contains chromosomes and controls cell metabolism and division
Wall Pressure - A cell taking in water by osmosis inflates until its cellulose wall cannot be stretched
further, this restraining force is called wall pressure
Cholesterol - A substance found mainly in animal fats which form part of the cell membranes. Excessive
cholesterol in ones diet can lead to blocked arteries
Cilia - Small hair-like strands on the surface of certain cells i.e. paramecium. They flick back and forth
allowing for movement in fluids
Differentiation - The process by which cells become specialized to perform a particular function
Semi-permeable Membrane - A membrane which allows certain substances to pass through but
prevents others e.g. the cell membrane
Tissue - A collection of similar cells which work together to perform a particular function
Organ - Part of a living organism formed when different tissues work together to perform a general
function
Characteristics of all Living Things -
Nutrition respiration
excretion response
reproduction growth movement

3. CLASSIFICATION OF LIVING THINGS


Classification - The process of grouping animals by similar characteristics or heritage
Advantages of scientific name of organisms -
Avoids repetition of names
makes it easier for scientists to study organisms based on features of organisms
universally agreed upon system
Reason that humans of all races are the same species (Homo Sapiens) -
All have similar genetic constitution and morphology
can interbreed freely to give fertile offspring
Advantages of classification -
Makes it easier to identify an organism
easier to describe organisms in a group
helps predict characteristics present in organisms
creates a standard system for classifying organisms

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provides organized system


provides supporting evidence for evolution
Binomial Nomenclature - The process of giving living things two scientific names. The first name
belongs to the genus and the second name belongs to the species in which an organism belongs
Pedigree - A record of ancestral history of an individual shown in the form of a chart, table or diagram
Differentiate between homologous and analogous structures -
Homologous Structures - Structures performing different functions but having the same or similar origin
(e.g. limbs can be used for swimming, flying, running or grasping)
Analogous Structures - Structures performing the same function but having a different evolutionary
history (e.g. bats and birds can fly with wings but they originated separately)

TYPES OF CLASSIFICATION SYSTEMS


Artificial Classification - A method of grouping organisms by their physical characteristics together (ie
all animals with wings)
Advantages -
Stable system
easy to identify organisms
less expensive
doesn’t consume time
Disadvantages -
Unrelated organisms are grouped together
has no predictive value
Natural Classification - A method of grouping organisms by biological similarities showing the real
relationship between organisms
Advantages -
Has predictive value
more information about members in each group
evolutionally closely related organisms are placed together in the same group
Disadvantages -
Expensive
requires more experiments
time consuming
difficult to identify organisms
only organisms with many features will be easily identified

MAJOR GROUPS OF LIVING THINGS


VIRUSES -
Characteristics of Viruses -
Require nutrients
reproduce (inside a living cell)
grow by producing a new protein coat

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lacks respiration and production of energy


no true cell structure, no evidence of sensitivity
does not feed/excrete/grow/respire
Differences between Viruses and Bacteria -
Viruses have only DNA or RNA but not both
bacteria have both RNA and DNA
outer layer of a virus is covered in protein material called a capsid
the outermost surface of a bacterium is covered by a slime capsule
viruses have no cell walls
bacteria possess cell walls
viruses do not have chromosomes
bacteria possess chromosomes
viruses do not have structures for locomotion like flagella
viruses do not have food granules for food storage
Major basic structures of a virus -
Core (Head) - Contains genetic material (DNA/RNA)
Endplate - What the virus uses to attach to a cell
Capsid (Coat) - A protective coat of protein surrounding the core
Envelope - The additional layer of protein around the capsid found in viruses like HIV
and influenza
KINGDOM MONERA
Characteristics of Monera -
Single celled
have no nucleus
have a single circular chromosome
Functions of Antibiotics -
Kill microorganisms
prevent multiplication of microorganisms
Examples of antibiotics - Penicillin, streptomycin
Nitrifying Bacteria - Bacteria in the soil which convert the decaying remains of organisms into
soil nitrate
Nitrogen Fixing Bacteria - Bacteria in the soil and root nodules which convert nitrogen in the air
to soil nitrates
Prokaryote - A group of organisms lacking a cell nucleus (ex bacteria)
Economic importance of Bacteria -
Positive -
Decomposition of pollutants i.e. urea/carbon dioxide
decomposition of dead organic matter
nitrogen fixing in soils to be used by plants
increasing soil fertility
manufacture vinegar/lactic acid/citric acid

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manufacturing certain kinds of medicine


production of cattle feed
creation of hormones
Negative -
Causes diseases
spoils food/vegetables
denitrification
KINGDOM PROTOCTISTA
Eukaryote - A group of organisms with a cell nucleus (ex plants, animals)
Characteristics of Protoctista -
Mainly aquatic
single celled
one nucleus
move by pseudopodia
cilia or flagella
some parasitic
Examples of Protozoa - Amoeba, paramecium, plasmodium
Flagellum - A tail like projection that protrudes from a cell body whose function is
locomotion
Importance of Protozoa -
Positive -
Algae release oxygen for animals to breathe
carbon dioxide absorption is carried out by algae
form the base of food chains
seaweed can be used as fertilizer
Negative -
Cause diseases like malaria
dysentery
sleeping sickness

1. CLASSIFICATION OF LIVING THINGS


KINGDOM FUNGI
Hyphae - Fine hollow threads which make up the body of many fungi, their purpose is to digest
and absorb nutrients by secreting enzymes outside of the cells and absorbing the
products of this digestion
Mycelium - A collection of hyphae
Rhizoids - Hair-like structures of mosses or fungi that absorb water and nutrients

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Decomposers - Fungi and certain bacteria which breakdown (decompose) dead organisms into
humus and minerals
Chitin - The main component of cell walls of fungi, exoskeletons of arthropods and insects
Saprotrophs - Organisms which feed on organic matter such as the dead remains of animals
and plants by releasing enzymes that digest the food externally, reducing it to a liquid
which is absorbed into the saprotroph’s body (e.g. certain types of bacteria and
fungi/mushrooms)
Economic importance of Fermentation -
Breweries manufacture alcoholic drinks like beer and wine
baking bread (leavening of bread by fermentation)
fermentation of tobacco leaves to make cigarettes
Characteristics of Fungi -
Mainly terrestrial
no chlorophyll
saprophytic
mycelium consisting of filaments called hyphae
cell wall of fungal cellulose
sexual reproduction
Examples of Fungi -
Rhizopus, mushroom, penicillium, mucor
Characteristics of Ascomycota (kingdom Fungi) - Reproduces asexually
Examples of Ascomycota - Yeast
Economic importance of yeast -
Alcohol production
bread production
Importance of Fungi -
Positive -
Yeast is used for fermentation
used to manufacture penicillin
production of citric acid
used in research
Negative -
Causes decomposition of natural materials like leather and wood
can spoil food
can cause disease
KINGDOM PLANTAE
Characteristics of kingdom plantae -
Have cellulose in their walls
capable of photosynthesis
body is differentiated into tissues
organs and systems

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Characteristics of Algae -
Aquatic
possess chlorophyll
body not differentiated into root
stem or leaf
sexual reproduction by swimming gametes
Examples of Algae -
Green, red and brown seaweed, spirogyra
Epiphyte - A plant that grows upon another plant (ex. tree) non-parasitically
Hydrophytes (Aquatic Plants) - Plants that have adapted to living in or on aquatic environments
Mesophytes - Terrestrial plants which are adapted for neither dry nor wet environments
Xerophytes - Plants that can survive in an environment with little available water (e.g. cacti)

Division Bryophyta (Mosses)


Bryophyta - A plant body not differentiated into root, stem and leaves such as mosses
Characteristics of Bryophyta -
Terrestrial
may have stem and leaf like structures
well defined sexual reproduction
has chlorophyll
plant body not differentiated into root
stem and leaves
no vascular tissues
live in damp shady places
Examples of Bryophyta - Mosses
Characteristics of Hepatica (Liverworts) -
Rhizoids are unicellular
simple sporophyte with no chlorophyll
Examples of Liverworts – Pellia

Division Filicinophyta (Pteridophyta) (Ferns)


Characteristics of Pteridophyta -
Terrestrial
highly differentiated with body and stem
leaf and root structures
high degree of internal tissue differentiation
possess chlorophyll
well defined sexual reproduction
found in water
arid country or as epiphytes in trees
Examples of Pteridophyta – Ferns

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2. NUTRITION
Autotrophs - An organism that produces its own food by photosynthesis (ex plants, producers)
Heterotrophs - An organism that gets its nutrition from other animals or plants or from the environment
(ex. animals, fungi, bacteria)
Balanced Diet - A diet which contains all types of food nutrients at the right proportions for a healthy
human
Constituents of a Balanced Diet -
Carbohydrates
proteins
fats and oils
vitamins (A, B, C, D, K)
mineral salts
water
roughage (fiber)
Carbohydrates - Energy source for living things (ex glucose, sucrose)
Sources of carbohydrates - Wheat, maize, cassava
Proteins - Used as building blocks of tissue and muscle in the body. All proteins contain nitrogen,
carbon, hydrogen and oxygen
Sources of proteins - Beans, meat
Fats and Oils - Provides energy to the body and insulates it from heat loss
Sources of fats and oils - Peanuts, cashews, coconuts
Vitamins - Essential for normal health in a variety of roles
Vitamin A - Necessary for normal growth in children and for proper functioning of eyesight
Vitamin B - Strengthens the muscles of the body
Vitamin C (Ascorbic Acid) - Strengthens the gums and is involved in fighting disease
Vitamin D - Helps strengthen bones
Vitamin K - Essential for the process of blood clotting
Mineral Salts - Used in the development and maintenance of bones (iodine, calcium, iron, sodium,
phosphorus, magnesium)
Water - The main solvent in the body
Roughage (Fiber) - Encourages peristaltic movement

MALNUTRITION -
Deficiency disease caused by overfeeding or underfeeding as a result of an unbalanced diet
Causes of malnutrition -
Poverty ignorance diseases
religious beliefs or taboos
crop failure war
early weaning
lack of access to different types of foods

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DISEASES CAUSED BY MALNUTRITION


Kwashiorkor - Caused by a lack of proteins
Symptoms -
Retarded growth
swelling of limbs due to excess body fluids
loss of appetite
loss of weight
anemia
change in the colour of hair from black to light brown
Treatment -
Providing a child with a balanced diet containing protein
Marasmus - Caused by a lack of carbohydrates providing energy
Symptoms -
Crying often
wrinkled skin
loss of weight
good appetite present
Treatment -
Provide a balanced diet with carbohydrates
Obesity - Occurs when a person eats too many carbohydrates
Symptoms -
Person becomes overweight or obese due to body fat depositions in their body
Treatment -
Exercise more
eat less carbohydrate rich foods
maintaining a balanced diet Vitamin E is produced by humans
Effects of Mineral Deficiency -
Iodine - Goiter
Calcium - Weak bones and teeth
Iron - Anemia
Sodium - Muscle cramps

DIGESTIVE SYSTEM IN HUMANS


Why a person can swallow something while standing on their head -
Once food enters the esophagus a series of wave-like muscular contractions in the walls of the
esophagus (peristalsis) start and the food is pushed towards the stomach and other parts of the
alimentary canal
Metabolism - All of the chemical and physical processes necessary for life
Anabolism - The chemical reactions of metabolism that build up complex substances from simple
materials, they require energy which comes from catabolism

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Catabolism - A chemical reaction of metabolism which breaks down complex substances into simple
ones and release energy
Biological importance of Saliva -
Contains the digestive enzyme salivary amylase which digests starch to maltose,
lubricates food for easier swallowing
Importance of Bile -
Salts in bile break down fats through emulsification
reacts with fat soluble vitamins (A,D,E,K) to make them water soluble
salts in bile neutralize HCl
Autolysis - Refers to the destruction of a cell through the action of its own enzymes i.e. self digestion
Lipase - An enzyme which digests fats and oils
Catalysts - Substances that increase the speed of a chemical reaction and are used up in the reaction
i.e. enzymes
Deanimation - The breakdown of unwanted amino acids in the liver by removal of nitrogen containing
part of the nucleus
Distase - An enzyme which digests stored starch in seeds
Emulsification - Breakdown of fats into droplets
Protease - An enzyme which digests protein
Trypsin - An enzyme produced by the pancreas which digests proteins converting them to amino acids
Enzymes which digest protein cannot digest starch because different enzymes can only break
down specific types of substrates
Absorption - The movement of digested (soluble) food through the walls of the alimentary canal into the
blood stream
Amylase - A type of enzyme which digests carbohydrates,
Alimentary Canal (Gut) - A tube running from the mouth to the anus inside which digestion and
absorption take place
Assimilation - Utilization of digested food to build cells in the body
Bile - A greenish-yellow liquid made in the liver which is passed into the duodenum where its function is
to aid in the digestion of fats
Cecum - A part of the intestine at the junction between the ileum and colon, serves no function in man
but is used for digestion of cellulose in herbivores
Chyme - The semi-fluid mass of partly digested food expelled by the stomach into the duodenum
Cilium - An organelle found in eukaryotic cells which help to move nutrients or other cells along in the
organism
Colon - Part of the large intestine, its function is to absorb water and mineral salts from feces
Digestion - The process by which food is made soluble by the action of digestive juices (enzymes)
Dormancy - A resting, inactive condition in which metabolism almost stops
Duodenum - The part of the alimentary canal between the stomach and the ileum
Esophagus - The tube through which food passes from the mouth to the stomach
Fatty Acids - Chemical components released when fats are broken down during digestion

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DIGESTIVE SYSTEM IN HUMAN
Fermentation - The breakdown of sugar by
organisms such as yeast and bacteria
which takes place under anaerobic
condition
Gastrointestinal Tract - Refers to the
stomach and intestines
Gall Bladder - A small bladder inside the
liver where bile is stored
Glycogen - A carbohydrate similar to starch.
It is stored in the liver and muscles of
mammals and then is converted into
glucose as the body requires energy for
metabolism
Hepatic Portal Vein - Vessel in which
blood containing absorbed food is carried
from the intestine to the liver
Lacteal - Part of the lymphatic system
which extends through the centre of the
villus. Its purpose is to absorb digested fat
from the ileum
Larynx - The voice box
Mucus - A sticky fluid produced by
goblets cells
Pepsin - An enzyme produced by the stomach which begins the digestion of proteins
Peristalsis - A wave-like contraction of the tubular organs such as the alimentary canal (gut) which
propels the contents of the tube in one direction
Pharynx - An area at the back of the mouth immediately above the trachea and esophagus
Rectum - The last part of the alimentary canal
Saliva - Fluids produced and released into the mouth by three pairs of salivary glands in response to
food. Contains the enzyme salivary amylase, mucin and minerals. Saliva is alkaline so the pH will
be lowered
Sphincter - A ring of muscle found in the walls of tubular organs such as the alimentary canal whose
contraction slows or stops movements of substances through the tube
Stomach - A bag like organ at the end of the esophagus
Trachea - The wind pipe
Villi - Minute finger-like structures on the inner surfaces of the duodenum and ileum. These occur in the
millions greatly increasing the surface area available for absorption
Liver - Detoxifies poisonous substances in the body such as alcohol, performs deamination to break
down amino acids and form urea

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Functions of the Liver -


Helps regulate blood sugar levels
stores fat to prevent starvation
deamination
storing vitamin A and D
stores iron from broken down erythrocytes (red blood cells)
Ileum - The region of the alimentary canal between the duodenum and colon where digestion is
completed and absorption takes place, small intestine. It also secretes intestinal juice
Intestinal Juice (Succus Entericus) - Juice containing proteins which help to break down food
substance as it passed through the ileum

Contents and roles of Intestinal Juice -


Mucus - Helps to lubricate the intestinal wall and prevents autolysis
Mineral Salts - Produced in order to neutralize the acid chyme from the stomach and to provide a
more suitable pH for the action of enzymes in the intestine
Enzymes -
Protease - Convert peptides into smaller peptides and amino acids and hydrolyses
dipeptides into amino acids
Enterokinase - A non-digestive enzyme which activates the trypsinogen produced by the
pancreas
Nucleotidase - Converts nucleotides into sugars, organic bases and phosphoric acid
Carbohydrases -
Amylase - Completes the hydrolysis of starch to maltose
Maltase - Hydrolyses maltose into glucose
Lactase - Hydrolyses lactose (the sugar in milk) into glucose and galactose
Sucrase - Hydrolyses sucrose into glucose and fructose

Factors affecting the absorption of digested food in the ileum -


-Being well supplied with blood capillaries to ensure digested food substances are absorbed into
the blood
-must have a thin epithelial lining which is permeable to molecules like glucose which will
increase the rate of diffusion of the digested food substances
-the epithelial cells must be rich in mitochondria to provide energy for their activities since the
absorption of some nutrients must be forced since absorption is taken against their
concentration gradient
-must possess a large surface area for absorption
Efficient absorption in the ileum through a large surface area is achieved in the following ways -
It is long (almost 6m in humans)
its walls are folded to provide large internal projections
the folds themselves have numerous villi
the epithelial cells lining the villi are covered with minute projections called microvilli

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NUTRITION REQUIREMENTS IN PLANTS


Tubers - Various types of plants with modified structures that are enlarged to store nutrients
Root Tubers - A modified root whose purpose is as a storage organ (ex. cassava, sweet potatoes)
Stem Tubers - A plant with a modified stem whose purpose is as a storage organ (ex. Irish potatoes)
Uses of elements in plants -
Phosphorus -
Source - Phosphate
Role - Synthesis of proteins, nucleic acid and ATP
Deficiency - Stunted growth, particularly of roots
Nitrogen -
Source - Nitrates and ammonium
Role - Protein synthesis, nucleic acid and chlorophyll synthesis
Deficiency - Stunted growth, chlorosis
Calcium -
Source - Calcium
Role - Formation of middle lamella of cell walls
Deficiency - Stunted growth
Iron -
Source - Intermediate in chlorophyll synthesis
Role - Chlorophyll synthesis
Deficiency - Strong chlorosis particularly in young leaves
Trace Elements - Minerals which are essential for the healthy growth of plants but which are required
only in minute quantities e.g. boron
Carbohydrates - Compounds containing carbon, hydrogen and oxygen which are the main source of
energy for metabolism, i.e. starch/sugar
Vitamins - Chemicals required in small amounts to maintain health
Proteins - Compounds used in the building and repair of muscles and tissues as well as the creation of
catalysts
Enzymes - Protein substances which act as catalysts and control the rate of chemical reactions in cells,
speeding them up
Hydrolysis - A chemical reaction where molecules of water are split into hydrogen cations (H+) and
hydroxide anions (OH-)

PHOTOSYNTHESIS
Photosynthesis - The process by which plants use light energy trapped by chlorophyll to form sugar out
of carbon dioxide and water
Necessary conditions for photosynthesis -
Presence of chlorophyll and sunlight
Raw materials of photosynthesis -
Water, carbon dioxide

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Products of photosynthesis -
Glucose, oxygen
Roles of photosynthesis -
Produces food used by plants and animals
produces oxygen used for respiration in animals
reduces carbon dioxide concentration in the atmosphere
Chloroplasts - Small bodies within cytoplasm containing chlorophyll. It is the where photosynthesis
occurs producing carbohydrates for the plant
Chlorophyll - Green substance in plants which absorbs light energy for use in photosynthesis
Importance of chlorophyll - To trap sunlight energy and keep it available in leaves as chemical energy
Compensation Point - The point at which photosynthesis and respiration in a plant are exactly balanced,
and one process uses up the products of the other
Variegated Leaves - Is the appearance of different coloured zones on leaves, such as white on the outer
rim and green in the middle. This is because the green parts of the leaf contain chlorophyll for
producing energy and the white parts do not contain chlorophyll (so they do not provide energy)
Requirements for the formation of Carbohydrates in Plants -
Sunlight carbon dioxide
water chlorophyll

FOOD PROCESSING, PRESERVATION AND STORAGE


Methods of Food Preservation -
Refrigeration (cold) - Inactivates microbes by freezing the water used in cell activity
and prevents their enzymes from being active
Drying Food (dehydration) - Removal of moisture from foods which inhibits microbial activities by
blowing hot air over food or by drying food over a fire or smoking
Heat - Cooking or sterilization by heat kills microbes by destroying their cell walls and other
proteins
Canning - After heat has killed all microbes, the food is placed in a can which prevents new
microbes from entering
Pasteurization - Food or milk is heated up to about 60°C and abruptly cooled too kill microbes
Control of pH - Microbes grow in acidic conditions, so vinegar or lactic acid can be used to
prevent growth
Salting (Osmolarity) - Salted foods lose water so microbes cannot grow, sugar can be used
Irradiation - Use of radiation to kill microbes, commonly used for medical supplies or drugs
chemical preservatives - Chemicals are used to kill microbes
Advantages of local food preserving methods -
No chemicals are added to foods
less expensive
does not require much knowledge
keeps a variety of foods for future use

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excess food can be stored


allows for transportation and storage of food

3. BALANCE OF NATURE
Balance of Nature - A situation where losses in the ecosystem are equal to replacements and the
materials present are reused again and again
Environment - Is a natural unit consisting of living (biotic) components and non-living (abiotic) that
interact with each other
Ecosystem - All the interaction between the members of a community and its environment
Habitat - A region of an environment containing its own particular community of organisms
Ecology - The study of interrelationships between living things and nonliving things in an environment
Community - A group of independent organisms which share a common environment
Colonization - The movement of animals and plants into a newly formed habitat
Niche - The place filled by an organism in an environment based on how it eats, lives or mates
Population - The number of organisms of a certain species living in an area at a time
Succession - The process by which one set of organisms gives way to another within a community
Water Cycle - Circulation of water between water vapour in the air and the water on and under the
ground
Nitrogen Cycle - The circulation of nitrogen from the atmosphere to soil bacteria, soil nitrates, plants,
animals and back to the atmosphere
Carbon Cycle - The continuous circulation of carbon atoms between atmospheric carbon dioxide and the
bodies of living organisms

INTERACTION OF ORGANISMS IN THE ENVIRONMENT


Carnivore - A flesh (meat) eating animal (ex. lion, tiger)
Consumers - Organisms in a food chain which live by consuming (eating) other organisms
Detritus - The decaying remains of dead animals and plans
Herbivore - An animal that eats only plants i.e. horse, sheep
Host - An organism in or on which a parasite lives i.e. a lion or human being
Parasite - An organism which feeds on the nutrients of another organism, generally feeding on their
blood (ex. fleas, lice, ticks)
Omnivore - An animal that eats both animals and plants e.g. man
Species - A group of organisms which can mate together and produce fertile offspring
Symbiosis - A close association between two different organisms in which both benefit
What would happen if…
All predators were removed from an ecosystem - The system would collapse because it would result
in a huge increase in the numbers of prey. Since prey primarily eat vegetation, they would end up
eating all of the vegetation leading to massive starvation from the lack of food
All bacteria were removed from an ecosystem - The system would collapse because the important
processes of recycling nutrient elements by decomposition would not be done which would end
the cycling of nutrients through the ecosystem

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Types of Relationships between Organisms -


Commensalism - A relationship between two organisms in which one organism benefits, but the
other is unaffected
Mutualism - The way two organisms biologically interact benefits both organisms
Competition - An interaction where the fitness of one organism is lowered in the presence of
another by limiting the access of a particular resource by one organism
Parasitism - A type of symbiotic relationship between organisms of different species where the
parasite benefits at the expense of the host
Difference between Parasite and Vector -
Parasite - A living thing which obtains food from a living body of another organism called the host
Vector (Carrier) - It is an organism which carries a parasite to its primary host
Factors affecting the population of a species -
Disease
predators
limitations of the food supply

FOOD CHAIN AND FOOD WEBS


Food Chain - A sequence of organisms through which energy is transferred. The first organisms are
producers (usually green plants) and the succeeding links are the consumers
Food Web - A number of interconnected food chains
Trophic Levels - The position that a certain organism occupies in a food chain
Trophic levels in an Ecosystem -
Producers - Organisms like green plants that produce food; starting point of food chains
Primary Consumers - Zooplankton
Secondary Consumers - Small fishes
Tertiary Consumers - Large fishes
Quaternary Consumers - Humans
General food chain structure -
Trophic level 4 - Tertiary consumer (top carnivore, ex hawk) - Top
Trophic level 3 - Secondary consumers (carnivores, ex small birds)
Trophic level 2 - Primary consumers (herbivores, ex snails and earthworms)
Trophic level 1 - Producers (plants) - Bottom
Difference between food chain and food web -
Food chains show a single path of animals consuming each other, from the producers at the
bottom to the highest consumers at the top
Food webs show how animals and plants are connected through different paths showing how life
in an ecosystem is connected
Green plants are known as producers because they make food from simple substances

4. TRANSPORT OF MATERIALS IN LIVING THINGS


Osmosis - Passage of molecules through a semi-permeable membrane from a weak to a strong solution

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Diffusion - The movement of molecules of liquids or gases in regions where they are highly concentrated
until they are equally distributed
Osmotic Potential - The pressure which molecules could diffuse from a solution if it were separated from
another solution by a semi-permeable membrane
Concentration Gradient - Represents the difference in concentration of a substance between two places
Plasmolysis - The shrinking of a cells cytoplasm due to the loss of water by osmosis
Mass Flow - The movement of fluids through a vessel or tube without passing through a membrane
Difference between osmosis and diffusion - Osmosis involves the movement of water molecules from
a low concentration to a highly concentrated region, whereas diffusion is the movement of
molecules of from a highly concentrated region to a lowly concentrated one
Hypertonic Solution - A solution which has more solute in concentration and less water molecules
Effects on a cell - It will lose water by osmosis and as a result will undergo flaccidity
Hypotonic Solution - A solution which has more concentration of water molecules and less solute
Effects on a cell - The solution is more diluted, so it will absorb water from its surrounding resulting in
the cell undergoing turgidity

TRANSPORT OF MATERIALS IN MAMMALS


Structure of the Mammalian Heart
Aorta - The largest artery in the body which originates from the left ventricle and extends down the
abdomen distributing oxygenated blood to all parts of the body
Coronary Artery - Maintain blood flow in the heart muscle
Diastolic Blood Pressure - Causes blood from contracting auricles to flow into ventricles
Inferior (Posterior) Vena Cava-
A large vein which carries
deoxygenated blood from the
posterior half of
the body to the right atrium of the
heart
Pulmonary Artery - Arteries
which carry blood from the heart
to the lungs
Pulmonary Vein - A large blood
vessel which
carries blood from the lungs to
the left atrium of
the heart
Semi-lunar Valve - Pocket like
valves in the main
arteries at the point where they
leave the heart whose purpose is

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to stop blood from flowing back into the ventricles


Superior Vena Cava - The vein which carries deoxygenated blood from the upper half of the body to the
right atrium of the heart
Systolic Blood Pressure - Causes blood from contracting ventricles to flow into pulmonary arteries and
the aorta
Vena Cava - The main vein of the body
Ventricle - One of the large thick walled lower chambers of the heart that pumps blood into arteries
Four chambers of the heart -
Right Atrium - Receives deoxygenated blood from the superior and inferior vena cava and
pumps it into the right ventricle through the tricuspid valve
Left Atrium - Receives oxygenated blood from the pulmonary veins and pumps it into the left
ventricle
Left Ventricle - Receives oxygenated blood from the left atrium vial the bicuspid (mitral) valve
and pumps it into the aorta via the aortic valve
Right Ventricle - Receives deoxygenated blood from the right atrium via the tricuspid valve and
pumps it into the pulmonary artery via the pulmonary valve
Types of heart valves -
Atrioventricular (AV) valves, semilunar (SL) valves
Atrioventricular Valves - Valves between the atria and the ventricles
Types of Atrioventricular Valves -
Tricuspid Valve - A valve on the right side of the heart between the right atrium and right
ventricle
Bicuspid (Mitral) Valve - A dual-flap valve in the heart which lies between the left atrium and
the left ventricle
Semi-lunar (Heart) Valve - Allows blood to flow through in one direction leaving the heart
Types of Semi-lunar Valves -
Aortic Valve - The valve which lies between the left ventricle and the aorta
Pulmonary Valve - The valve which lies between the right ventricle and the pulmonary artery
Heart Attack - A sudden stoppage of the heart beat which is commonly caused by a blockage of a
coronary artery due to thrombosis

THE BLOOD
Mammalian blood consists of -
Plasma - The liquid part of the blood
Contains - Water, proteins, minerals, end products of digestion, hormones
Functions of plasma -
Transports carbon dioxide, waste matter, hormones, digested food, heat, ions
and water, white blood cells and platelets
Blood Cells - Red, white, platelets
Red Blood Cells (Erythrocytes) - Disc shaped cells containing hemoglobin which transport oxygen from
the lungs to the body tissue

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White Blood Cells (Leucocytes) - The name for a number of colourless cells in blood e.g. phagocytes
and lymphocytes, they attack and engulf bacteria and produce antibodies
Platelets (Thrombocytes) - Particles in the blood which are used in the formation of blood clots to stop
bleeding of wounds

Difference between Arteries and Veins -

ARTERIES VEINS

• Transports blood away from the heart • Transports blood towards the heart
• Composed of elastic and smooth muscle • Only slightly muscular with a few elastic
tissue fibres
• No semi-lunar valves (except when leaving • Semi-lunar valves at intervals along the
the heart) • Pressure of the blood is low and no pulse is
• Pressure of the blood is high and has a detectable
pulse • Blood flow is slow
• Blood flow is rapid • Higher blood volume than arteries or
• Lower blood volume capillaries
•Carries oxygenated blood (except in the • Carries deoxygenated blood (except in the
pulmonary artery) pulmonary vein)

Functions of Blood -
-Transports oxygen
-continuous circulation of blood lowers body temperature
-distributes food from intestines throughout the body
-waste products such as carbon dioxide/mineral salts and urea are transported to organs
responsible for their excretion
-hormones are distributed
-white blood cells defend against bacteria
-maintains water levels in the body
-formation of cloths over injured parts to prevent excessive blood loss
Blood Proteins -
Albumins - Create pressure in the blood and transports other molecules
Immunoglobulins - Participate in the immune system
Fibrinogens - Are essential for blood coagulation (clotting)
Blood protects against diseases in the following ways -
Blood clotting by platelets and fibrinogen to prevent excessive blood loss and entry of pathogens
into the body, immunity by antibodies and lymphocytes, engulfing of bacteria present in the blood
performed by white blood cells

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Factors affecting Blood Pressure -


-Resistance to blood flow by blood vessels (peripheral resistance) due to fat deposition in blood
vessels
-diseases such as diabetes
-stress or emotional distress
-strength of the heart heat
-stroke volume
-eating salted food
-infections
-emotions
Hemoglobin - A red substance in a red blood cell whose purpose is to combine with oxygen to transport
it to tissues
Importance of hemoglobin -
Transportation of gases from lungs to body tissues and back to the lungs
Tissue Fluid - A fluid which is forced through capillary walls and moves between all cells of the body,
providing them with food and oxygen and removing their waste products
Fibrinogen - A protein in blood which is transformed into fibres of fibrin which block damaged blood
vessels and forms a blood clot
Capillaries - Small blood vessels which form a connection between arteries and veins
Capillary Narrow - A thin walled blood vessel which sends blood from arteries to veins. Exchanges of
gaseous or dissolved substances between the blood and body cells takes place through capillary
walls
Oxyhemoglobin - Hemoglobin which has combined with oxygen in the red blood cells
Pulmonary Circulation - The system of vessels that transport blood from the right ventricle to the lungs
and back to the left atrium
Thrombosis - The formation of blood clots which may block an artery and stop the blood flow to vital
organs
Vascular System (of mammals) - The heart and blood vessels
Hemophilia - An inherited blood disorder where blood from wounds clots very slowly or not at all

BLOOD GROUPS AND BLOOD TRANSFUSION


Donor - A person who donates blood voluntarily
Universal Recipient - A person with blood type AB can receive blood from all other groups without being
killed (except if there is a rhesus factor problem)
Universal Donor - A person with blood type O which can be given to all other groups without killing them
Agglutination - The clumping together of red blood cells which block small blood vessels leading to
death.
This is determined by the plasma and red blood cells of the recipient and donor during a blood
transfusion

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BLOOD GROUP ANTIGEN ON RBC ANTIBODY IN PLASMA


O No antigen Antibody A and B
A Antigen A Antibody B
B Antigen B Antibody A
AB Antigen AB No antibodies

How blood donation is determined -


If the blood of the donor possesses the antigen of the antibody of the recipient, it will result in
agglutination and death. For example, if a recipient of blood group A gets blood from a donor with
blood group B, the antibody will attack the antigen, causing the agglutination
Rhesus Factor Positive (Rh+) - Refers to people who possess the rhesus antigen
Rhesus Factor Negative (Rh-) - Refers to people who do not possess the rhesus antigen
Why a person of blood group AB is not always considered a universal recipient -
The presence of rhesus factors can still lead to an antigen-antibody reaction causing blood
agglutination. For example if a patient is given Rh+ blood, he will survive the first transfusion, but
the second transfusion results in an antigen-antibody reaction and agglutination because
antibodies were made after the first transfusion in response to the presence of the rhesus
antigen
Precautions taken during blood transfer -
The blood group of the donor must be compatible with that of the recipient, the rhesus factor of
the donor and recipient should be considered to determine if they are a match or not, the
donor’s blood should be safe from infections disease such as HIV

BLOOD CIRCULATION
Two-circuit circulatory systems (in
animals) -
Pulmonary circulation, systemic
circulation
Pulmonary Circulation -
Circulation of blood between the
heart and lungs
Systemic Circulation -
Circulation of blood in the rest of
the body (excluding the
lungs)
Types of circulatory systems -
Open, closed
Open Circulatory System -
The flow of blood from the heart to the body’s tissues and back to the heart without passing
through the blood vessels. Blood moves through a series of spaces
Closed Circulatory System - The flow of blood coming from the heart passes through different parts of

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the body through vessels and passes back to the heart


Spleen - An organ immediately below the stomach which produces white blood cells and destroys old
worn out red blood cells
Systemic Circulation - The series of vessels which carry blood from the left ventricle around the body
and back to the heart at the right atrium
Hepatic Portal Vein - The abdominal cavity that drains blood from the gastrointestinal tract to the spleen
and liver
Hepatic Artery - Blood vessel that supplies oxygenated blood to the liver duodenum and pancreas

THE LYMPHATIC SYSTEM


Antibodies - Chemicals made by the body in response to parasites or antigens that destroy them
Antigens - Bacteria, viruses or foreign substances in the body which stimulate the production of
antibodies
Toxin - A poisonous substance
Antitoxin - A type of antibody which neutralizes poisonous substances, particularly those produced by
parasites
Lymph - A liquid derived from tissue fluid after it has passed between the cells of the body and drained
into the lymphatic system
Lymphatic System - A system of vessels that transport lymph from the tissues to the circulatory system
Lymph Node - A part of the lymphatic system which contains phagocytes which remove germs and dead
cells from the lymph
Lymphocytes - White blood cells produced in the lymphatic system which make antibodies to destroy
antigens
Phagocytes - White blood cells that engulf and digest germs

Ways the body prevents infection of diseases -


First Line of Defense -
The Skin - Acts as a barrier against pathogens and produces sweat as a mild antiseptic
Acid and digestive enzymes in the stomach - HCl is secreted to kill most pathogens in
food and water which was ingested, beyond the stomach digestive enzymes in
the gut kill them
Respiratory System - Surfaces contain mucus to trap pathogens and cilia to sweep
them away
Second Line of Defense -
White Blood Cells (Leucocytes) - Pathogens can be killed by WBCs by phagocytosis
Antibodies - Chemical substances which protect the body by destroying the pathogens
and by neutralizing their toxins
Factors affecting the formation and flow of lymph -
High blood pressure
decrease in plasma proteins
blockage of lymph vessels

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Ways the body can remove or destroy bacterium -


In the eye - Tears,
on the hands - By washing,
in the bronchus - By sneezing,
in the stomach - By producing hydrochloric acid

Differences between Lymphocytes and Phagocytes –

LYMPHOCYTES PHAGOCYTES
• Secrete antibodies which fight • Destroy germs by engulfing microbes
germs • Do not secrete antitoxins. Instead they gather at
• Secrete anti-toxins wounds to destroy bacteria before they can enter
• Made in the lymphatic system the body
• Have large oval shaped nuclei and • Made in the bone marrow
no granules in their cytoplasm • Have a bi-lobbed (divided) nuclei and have
granular cytoplasm

TRANSPORT OF MATERIALS IN PLANTS


Lignin - A hard rigid substance which forms in the walls of cells which make up the xylem tissue
Vascular Bundle - Strands of xylem and phloem tissues running from the roots into the leaves which
transports food and water throughout the plant and supports softer tissues
Vascular System (of plants) - Xylem and phloem tissues
Vein (of plants) - A strand of xylem and phloem tissue
Structure of a plant - Leaves, roots, stems, buds, nodes, xylem, phloem
Xylem - A plant tissue which transports water and dissolved minerals from the soil to the leaves and also
supports the softer plant tissues. It consists of the xylem vessels and fibres
Translocation - The movement of substances within a plant such as sugar moving through phloem
Transpiration - The evaporation of water from plant cells and out of their stomata, cooling effect
Root Hair Cells - Their function is to absorb water and minerals from the soil
Root Hairs - Hair like outgrowth from single cells in the epidermis of a root in a zone near the root apex
Root Nodules - A swelling on the roots of certain leguminous plants (e.g. peas/clover) which contain
nitrogen fixing bacteria
Root Pressure - Pressure causing water to pass up the xylem from the living cells of the root
Petiole - A leave stalk
Phloem - A plant tissue that transports the products of photosynthesis from the leaves to the growing
points and food storage organs. It consists mainly of sieve-tubes and companion cells
Pedicel - A flower stalk
Pericycle - A cylinder of cells that lines inside the endodermis in plants

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Importance of Water for Plants -


1. Major component of protoplasm
2. Solvent for organic compounds
3. Transport fluid
4.Basic raw material for photosynthesis
5. Supports plants by keeping the shoots
turgid (stiff)
6. For cooling plants through evaporation from
leaves
Significance of transpiration -
Water transport
salt transport
temperature control
Problems resulting from transpiration -
Under dry conditions the plant may lose too
much water and begin to wilt or even die

LEAF STRUCTURE -
Spongy Mesophyll - A layer of cells in a leaf immediately below the palisade which contains large
intercellular air spaces
Palisade Mesophyll - A layer of cylindrical cells at right angles to the upper epidermis of leaves which
contain more chlorophyll than other plant cells and are the main cells concerned with photosynthesis
Chloroplasts - Organelles in plant cells which contain chlorophyll
Guard Cells - Crescent-shaped cells in the epidermis of plants which control the opening and closing of
the stoma. Contains chloroplasts and are able to photosynthesize carbohydrates
Stomata - Pores in the epidermis of
plants through which air enters and
leaves and water evaporates during
transpiration, used for excretion of
waste materials by plants
Epidermis - The outer layer of cells
in an animal or plant (skin), its
function is to protect inner tissues
from
physical damage. In plants they give
rise to the development of root hair
cells
Meristem - Tissue in plants consisting of undifferentiated cells found in zones where plant growth takes
place (ex. cambium)
Cambium - A region of unspecialized cells between the xylem and phloem of vascular bundles. Cell
division in the cambium produces newvascular tissue and increases the diameter of the stem

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Cellulose - A carbohydrate made of ling fibers which forms the rigid cell wall surrounding all plants
Lamina - The flat part of a leaf on either side of the mid-rib
Mid-Rib - The rigid rib in the centre of a leaf which contains the xylem and phloem
Adsorption - A force which holds water in a thin film around the surface of soil particles
Capillarity - Force that draws water upwards through narrow spaces such as those between particles of
soil
Turgidity - Is when a plant cell becomes full of water. This is necessary because it supports plants and
causes the growing tissues to extend and grow
Vacuole - A fluid filled space in the cytoplasm of a plant cell containing sap which creates turgor pressure
Turgor Pressure - The pressure within plant cells which results from the absorption of water by osmosis
A tree can die if you remove a ring of bark because the phloem tissues are destroyed blocking
translocation of food from leaves
Functions of Roots -
Anchors plant to the soil
absorbs water and mineral salts and transports them up to the stem
can be a storage organ
used for support
Functions of Stems -
Continuous conduction of water and mineral salts upwards to the leaves
supports leaves and holds them out to receive sunlight
supports flowers
can serve as a storage organ
Functions of Leaves -
Absorbs carbon dioxide for photosynthesis
contains chlorophyll
stomata allow for transpiration

Functions of Flowers -
Organ of reproduction
ovary forms the fruit which contains seeds

Difference between Roots and Stems -

STEMS ROOTS
• Have chlorophyll • Usually have no chlorophyll
• Have nodes and internodes • Do not have nodes and internodes
• Braches at nodes • Branches irregularly
• Produce leaves, flowers and fruits • Do not produce leaves, flowers or fruits
• Are covered by a cuticle or bark • Do not have a cuticle
• Have no stem cap • Have a root cap
• Have no root hairs • Have root hairs

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5. GASEOUS EXCHANGE AND RESPIRATION


Gas Exchange - The process by which an organism absorbs oxygen from the air in exchange for carbon
dioxide, takes places in respiratory organs like lungs
Gaseous Exchange - Is the exchange of gases between the blood and respiratory surface or between
the blood and respiring cells
Respiration - The exchange of carbon dioxide and oxygen in animals
Requirements for respiration in animals to occur - Medium for the gases (ex air or water), a large
moist respiratory system which can dissolve
the gases before they diffuse into our
out of the cells, a transport system to
move the dissolved gases around the
body to all of the cells and to collect
gases which need to be eliminated

GASEOUS EXCHANGE IN MAMMALS


Structures concerned with gaseous
exchange -
-Mammal - Lungs
-Young Tadpole - External gills
-Insect - Tracheal system
-Earthworm - Whole body through
diffusion
Spider - Book lungs
Adaptations of lungs for gaseous
exchange - Alveoli, moist, supplied by blood vessels, well ventilated
Large surface area - Alveoli increase the surface area for maximum contact with the air
Moist - The surfaces of alveoli are moist to enable easy diffusion of gases
Blood Supply - Blood supply ensures maximum absorption of oxygen
Ventilation - Well ventilated to receive a steady flow of new air

Differences between Villi (digestion) and Alveoli (respiration) -

VILLI ALVEOLI
• Found in the digestive system (alimentary • Found in the respiratory system (lungs)
canal) • Deal with exchange of gases between the
• Deal with absorption of food materials blood and environment
• Increase the surface area of the gut for the • Increase the area of the lungs for gaseous
absorption of food materials exchange

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Factors governing gaseous exchange at alveoli -


Concentration of gases (oxygen & carbon dioxide) in the blood and alveoli
walls of capillaries and alveoli are very thin to allow for easy diffusion of gases
blood pressure in the blood capillaries surrounding the alveoli is high
alveoli surfaces are moist and aid in rapid diffusion of gases
Ventilation - The movement of air or water across a respiratory surface such as a lung or gill which
enables gaseous exchange to take place
Breathing - Is the process whereby the air is exchanged between the environment and a multi-cellular
Organism

ORDER OF RESPIRATORY COMPONENTS -


Nasal Cavity > Pharynx > Trachea > Bronchi > Bronchioles > Alveoli
Alveoli - Bubble-like air pockets at the ends of the air passages in the lungs, they are surrounded by
blood vessels and are concerned with gaseous exchange
Bronchi (Bronchus) - Major pathway of air entering the lungs from the trachea
Bronchioles - Smaller branches of the Bronchi that end with alveoli
Diaphragm - Dome shaped sheet of muscle at the base of the thorax, part of the mechanism that
ventilates the lungs
Intercostal Muscles - The muscles between the ribs that raise the ribcage during inspiration (breathing
in)
Pharynx - Part of the throat where both food and air pass through leading to either the stomach or lungs
Pleural Cavity - The fluid filled space between the outer surface of the lungs and the inner surface of the
rib cage
Respiration - A sequence of chemical reactions which release energy from food
Trachea -The airway through which respiratory air passes in organisms
Thorax (of mammals) - The cavity in the chest which contains the lungs, heart and main blood vessels
Oxygen Debt - Occurs during strenuous aerobic exercise. It happens because there is not enough
oxygen in the body to oxidize the excess lactic acid produced. This is resolved by increasing the
rate of breathing during and after exercise to oxidize all of the lactic acid
The process by which carbon dioxide passes from the blood to the alveoli in the lung is diffusion

GASEOUS EXCHANGE IN PLANTS


Lenticel - An airy aggregation of cells with structural surfaces of the stems, roots and other parts of
vascular plants which functions as a pore for direct exchange of gases between internal tissues
and the atmosphere
Why it is not healthy to sleep in a closed room with many potted plants -
-Plants are unable to produce oxygen without sunlight because photosynthesis requires sunlight
-plants continue to respire which releases carbon dioxide into the environment
-the room would lose all of its oxygen and only have carbon dioxide which will cause a person to
suffocate

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RESPIRATION
Aerobic Respiration - A type of respiration where oxygen is consumed (ex humans)
ATP (Adenosine Triphosphate) - A chemical that transfers energy released by respiration to other
reactions in the body which absorb energy
Why metabolic activities use ATP instead of glucose as a source of energy -
The high energy phosphorus bonds of ATP easily release the energy for a cell to use, but the
energy stored in glucose requires more time and effort to process (it is a three step process). ATP
stores chemical energy from glucose at a high rate of efficiency
Mitochondria - Rod-shaped organelles in the cytoplasm of cells which is concerned with respiration
Anaerobic respiration
Anaerobic Respiration - A type of respiration in which oxygen is not consumed (ex yeast)
Denitrifying Bacteria - Anaerobic bacteria in soil which break down nitrates into nitrogen and oxygen
Fermentation is an example of anaerobic respiration

Difference between Aerobic and Anaerobic Respiration-

AEROBIC ANAEROBIC
Place it occurs Mitochondria Cytoplasm
Substrates Glucose and oxygen Glucose
Products Carbon dioxide and Alcohol and carbon dioxide in
water plants, lactic acid in animal
cells
Energy 38 molecules of ATP 2 molecules of ATP
produced

1. CLASSIFICATION OF LIVING THINGS


Kingdom plantae
Characteristics of Gymnosperma (Conifers) -
Trees and shrubs
flowers are cones
seeds are naked
evergreen
do not shed leaves regularly
soft wood
Examples of Gymnosperma - Redwood trees and other conifers
Advantages of conifers -
Grow fast
used to produce softwood

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used in building/paper/furniture
used as telephone poles
Disadvantages of conifers -
Demands greater use of preservatives
prone to termites
plantations use a lot of land
Division angiospermophyta (angiosperms)
Characteristics of Angiosperma -
Wide variety of forms including trees
shrubs and herbaceous plants
xylem acts as a vessel
flowers are common
hermaphrodite with seeds enclosed in a fruit
hardwoods
shed leaves regularly
Examples of Angiosperma - Maize, beans, oak trees, onions, grass
Uses of angiosperms -
Timber (hardwood)
medicine
paper
cotton
sisal fiber
crop

GROUPS OF FLOWERING PLANTS -


Monocot (Monocotyledon) - A group of flowering plants (angiosperms) whose seed has one embryonic
leaf (one cotyledon). (ex. grains, rice,maize, wheat, sugar cane etc)
Dicot (Dicotyledons) - A group of flowering plants (angiosperms) whose seed has two embryonic leaves
called cotyledons (ex. roses, magnolias etc)

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Difference between Monocots and Dicots

MONOCOTS DICOTS
• Has one embryonic leaf • Has two embryonic leaves
• Tap roots • Fibrous roots
• Vascular bundles spread around the middle • Vascular bundles in a ring
• Floral parts are arranged in three parts of • floral parts are arranged in fours or
multiples of threes fives or multiples of fours or fives
• Leaves are long and ribbon-like with veins • Leaves are different shapes and
arranged in a pattern parallel to the long axis of veins are arranged in a net pattern
the leaf

2. MOVEMENT
Locomotion - The ability of the whole body of an organism to move from one place to another
Types of locomotion -
Amoeboid - Movement is caused by extending cytoplasm in a certain direction
Ciliary - The surface of organisms is covered by thousands of small hair like cilia which are
coordinated to beat backward and forward causing the organism to move
Flagellar - Movement is caused by whipping a large cilia like tail in water, causing the organism
to rotate and move forward
Muscular - Movement is caused by the force generated by the contraction of muscles
Movement - The action of changing positions whereby a part of the body or the whole body of an
organism moves from one place to another
Pseudopodia (Fake Feet) - Projections from the cytoplasm of certain cells like amoeba that are used for
locomotion and feeding
Importance of movement to Living Organisms -
It enables living things to obtain necessary things like food, shelter or mates for their survival from
the environment around them
Types of movement used by the following organisms -
Amoeba - Amoeboid movement
Euglena - Flagellar movement
Paramecium - Ciliary movement
Birds - Muscular movement

THE HUMAN SKELETAL SYSTEM


Types of joints -
Hinge - A joint which can be lifted up or down similar to a door opening and closing (ex. knee and
elbow joints)
Ball and Socket Joints - Characterized by allowing movement in many directions including
rotation (ex. shoulder and hip joints)

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Pivot - A joint which allows a pivot to turn in a socket (ex. joint between axis and atlas vertebrae)
Gliding - found where two bone surfaces move over each other (ex. joints between vertebrae
and wrist joints)
Fixed - A type of joint formed by the fusing of bones which does not allow for movement (ex.skull)
Hydrostatic Skeleton - A structure found in many cold blooded organisms and soft bodied animals
consisting of a fluid filled cavity (coelom), surrounded by muscles which allow the organism to
change shape and produce movement (ex. jellyfish, earthworms, nematodes)
Humerus - A long bone in the arm that runs from the shoulder to the elbow
Articular Cartilage - Prevents surfaces or articulating bones from being worn out by function. Its cells
actively divide miotically to make he bone grow
Endoskeleton - A skeleton which forms inside the body of an organism
Exoskeleton - A skeleton which forms on the outside of an organism
Hydrostatic Skeleton - Support which comes from water in the cells of an organism
Synovial Fluid - Minimizes friction in a joint when bones move due to bending or straightening of the
limbs
Synovial Joint - Any freely moveable joint in the skeleton e.g. elbow
Synovial Membrane - Is the soft tissue that lines the non-cartilaginous surfaces with joints and cavities
(synovial joints)
Tendons - A strong band of fibres
which attaches muscles to bones
There are 7 vertebrae in the neck
(cervical vertebrae)
Atlas - The first cervical vertebra of
the spine, connects the skull to the
spine
Axis - The second cervical vertebra
of the spine, forms the pivot where
the atlas rotates

MUSCLES AND MOVEMENT


Types of Muscle -
Skeletal Muscle - Is muscle which is attached to bone and is concerned with locomotion
Cardiac Muscle - Is muscle found only in the heart
Smooth Muscle - Is found in the walls of organs in the body like the gut and bladder and is
concerned with movement of materials through them
Examples of Smooth Muscle -
Small arteries, veins, lymphatic muscles, urinary bladder, uterus, male and female
reproductive tracts, respiratory tract, gastrointestinal tract, ciliary muscle, iris
Antagonistic Muscle System - Two sets of muscles which oppose each other on either side of a joint
one side flexes (bends) and the other extends (straightens)

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Insertion (of a muscle) - The end of a muscle attached to the bone which moves when the muscle
contracts
Motor Endplate - Part of a motor neuron which is embedded in a muscle
Motor Neuron - A neuron which sends an impulse from the central nervous system to a muscle or gland
Origin (of a muscle) - The anchorage point of a muscle i.e. the end which does not move during
contraction
Oxygen Deprivation - Occurs in muscle tissue during strenuous exercise when oxygen is consumed
faster than it can be supplied by the blood
Adaptations of motor neurons -
Cell body is located at one end of the axon and is pointed towards the central nervous system to
help carry the action potential from the central nervous system, has short dendrites to ensure
that a fast response occurs, has a myelin sheath to ensure that the nerve impulse is traveling in
only one direction without any interference, has a node of ranvier to help increase the speed of
conduction of the nerve impulses (salutatory movement)
Difference between a ligament and tendon -
A ligament is a tissue which connects bone to bone at the joint, whereas a tendon is a part of a
muscle which attaches the muscle to the bone
Femur - Thigh bone which gives vertebrates the ability to walk or jump
Hyaline Cartilage - Its function is to reduce friction between bones during movement and to absorb
shock
Joint - The junction point where two bones meet
Ligament - A band of fibres around a joint of a skeleton which holds the bones in place preventing
dislocation, joins bone to bone at the joint
Vertebral Column - The backbone or spine. A chain of small bones called vertebrae that support the
body, protects the spinal cord and permits bending movements
Biceps and triceps are antagonistic muscles in a mammal’s arm, meaning when one contracts the other
relaxes

TEETH
Dentine - A substance similar to bone which forms in the inner part of the tooth beneath the
enamel
Diastema - The gap or space between teeth
Enamel - The extremely hard, white substance which forms the outer surface of a tooth
Incisor - Chisel-shaped teeth at the front of the jaws
Molars - Large teeth with four cusps, situated at the back of the jaw which are used to crush and
grind food

3. COORDINATION
Coordination - The linking together of the activities of different organs so that they work at an appropriate
time and rate required by the body
Components of coordination - Stimulus, receptor, coordinator, effector, response

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Stimulus - Anything which produces a response in an organism (ex. a painful burn on the skin)
Receptor - A part of an animal’s body which detects a change in the environment (ex. eyes, ears, nose,
skin, tongue)
Coordinator - An organ which receives messages as sensory nerve impulses from receptors and then
coordinates them to bring about a response
Effector - An organ which receives motor nerve impulses from the coordinator and brings about an
appropriate response (ex. glands and muscles)
Response - An activity provoked by a stimulus (ex. pulling hand away from a hot object)
Condition - A behaviour which has to be learned
Effector Organ - A muscle or gland that contracts or secrets in response to nerve impulses
Pathway from a stimulus to a response -
Stimulus inside a sense cell nerve impulse by a sensory neuron central nervous
system nerve impulse by a motor neuron effector-gland or muscle response

NEURONS
Axon - The nerve fiber of a neuron which conducts nerve impulses away from the cell body
Chemoreceptor - A receptor which detects certain chemical stimuli in the environment
Dendrites - Short numerous fibres which receive impulses and conduct them towards the cell body
Ganglion - A biological tissue
mass, most commonly as a
mass of nerve cells
Proprioceptor - A sensory
nerve ending which picks
up stimuli originating inside the
body e.g. a stretch receptor in
a muscle
Myelin Sheath - A fatty
material that insulates and
protects the axon and speeds
up the transmission of impulses
Neuron - A nerve cell consisting of a cell body and nerve fibres which conducts nerve impulses
Node of Ranvier - Gaps formed between myelin sheaths of different cells
Receptors - The regions of sensory nerve fibres where stimuliare received and converted into nerve
impulses e.g. rods and cones of the eye
Synapse - Microscopic gap which the nerve impulses pass when moving from one nerve cell to the next
Synaptic vesicles - Contain the neurotransmitters which carry the impulses when one neuron is
associated with another
Threshold - The level of stimulation at which nerve impulses begin to pass from a sense organ, or to
cross over a synapse
Nerve Impulse -

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How a nerve impulse is propagated across a synapse -


The arrival of nerve impulses in the presynaptic knob causes the synaptic vesicles to move and
fuse with the presynaptic membrane. Then the vesicles burst to release chemical transmitters
which diffuse across the gap to the postsynaptic membrane of the other neuron. Then they are
received by the post-synaptic membrane causing the depolarization of the post- synaptic neuron
and the nerve impulse proceeds to travel to the post-synaptic neuron until its destination
Characteristics of a nerve impulse -
Have high conductivity and high excitability
Why the nerve impulse travels only in one direction - This is because the neurotransmitters are found
only on the presynaptic knob meaning that impulses can only travel from the presynaptic neuron
to the post-synaptic neuron

CENTRAL NERVOUS SYSTEM


Medulla Oblongata - The lower half of the brainstem which deals with breathing, heart rate and blood
pressure
Pituitary (Master) Gland -
An endocrine gland that
secretes hormones
regulating homeostasis. It is
said to be the master gland
because it secretes
hormones which control the
function of other glands
Central Nervous System -
The brain and spinal cord
Cerebellum - The part of
the brain which
controls balance and muscular
coordination
Cerebral Cortex - Gray matter which
forms the outer layer of the cerebral
hemispheres, controls voluntary
movements and is concerned with memory, thinking and learning
Cerebrum - Responsible for thought, memory, intelligence and judgment
Cerebral Hemispheres - Two swellings in the front of the brain which form the largest region in the
human brain and are concerned with consciousness, learning and memory
Gray Matter - Nervous tissue in the brain and spinal cords consisting mainly of neuron cells
Hypothalamus - The reflex centre concentrated with mechanisms like temperature control, water balance
and carbon dioxide levels in the blood
Olfactory Lobes - Receives sensory impulses from the organ of smell and is connected to the cerebrum
Optic Lobes - Receives sensory neurons from the eye

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Sensory Neuron - A neuron which conducts impulses from a receptor (e.g. sense organ) to the central
nervous system
Spinal Cord - A long thin tubular bundle of nervous tissue and support cells from the brain which makes
up the central nervous system
White Matter - Nervous tissue in the brain and spinal cord which consists of nerve fibers

REFLEX ACTION
Orientation Behaviour - The behaviour which allows animals to move in a particular direction depending
on a received direction
Irritability - The ability of an organism to respond to stimuli
Reflex - A response that does not have to be learned and occurs very quickly without conscious thought
e.g. withdrawing from a painful stimulus
Conditioned Reflex Action - The fast automatic response to a stimuli resulting from learning
Importance of conditioned reflex actions in living organisms -
Helps change the animals behavior so that it will behave in a way that allows them to survive
produces responses which are favorable (ex. a child responding to their parents voice)
helps keep animals away from predators and to escape them
Types of Action -
Reflex Action - A fast automatic response to a stimuli which is not controlled by will power
Voluntary Action - An action performed by an individual which is controlled by will power
Order of a simple reflex in the body -
Receptor organ stimulated Impulse travels in sensory fiber Impulse crosses synapse
Impulse travels in motor fiber Effector organ stimulated

Difference between a Reflex Action (animals) and Tropism (plants) –

REFLEX ACTIONS TROPISM


• Occurs quickly • Occurs slowly
• Short term response • Long term response
• Conducted through nerve impulses • Conducted by hormones secreting to the point
through neurons of cell elongation by diffusion

SENSE ORGANS
Receptors used in mammals for each type of stimulus –

Stimulus Light Sound Chemical Gravity Temperature Texture Pressure


Receptors Eyes Ears Nose and Ears Skin Skin Skin
tongue

THE EYE

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The process of image formation -


Light rays from an object enter the eye through the cornea, and then they pass through the
aqueous humour to the pupil to the lens to the vitreous humour and finally reach the retina. As the
light passes through the lens, cornea and aqueous humour, a partial refraction of the light occurs
with the greatest amount of refraction occurring through the lens. The refraction directs light rays
towards the centre of the eye which fall on the retina forming an image of the object. The image
formed is real, inverted and smaller than the object. When the light rays fall on the retina, they
stimulate photoreceptors which set up an action potential which is then sent to the brain through
the optic nerve. The cerebrum interprets the impulses to create the real object in terms of
orientation and size

DEFECTS OF A MAMMALIAN EYE -


1. Myopia (Short-sightedness) - A defect of the eye whereby a person cannot focus on distant objects
properly, but can focus on nearby objects properly
Causes - It is caused by the extension of the eyeball which results in an increase in the distance
between the lens and the retina
Correction - It is corrected by using a biconcave lens (glasses) to diverge the light rays so they can
be focused on the retina
2. Hypermetropia (Long sightedness) - A defect of the eye whereby a person cannot focus on nearby
objects properly, but can focus on distant objects properly
Causes - It is caused by the compression of the eyeball, resulting in the shortening of the normal
distance between the lens and the retina
Correction - It is corrected by using a biconvex lens (glasses) to focus light on the retina

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Accommodation - Is the reflex mechanism by which light rays from an object are brought to focus on the
retina. It is the ability of the eye to focus an image of near or distant objects
Blind Spot - The point at which the optic nerve leaves the retina of the eye. It is not sensitive to light
Ciliary Muscles - Muscles in the eye which change the shape of the lens during accommodation
Cones - Cone-shaped, light sensitive cells in the retina of the eye which work only in bright light and are
sensitive to colour
Conjunctiva - The transparent skin which covers and protects the front of the eye
Cornea - Transparent, circular window at the front of the eye which focuses light
Fovea - Region of the retina immediately opposite the lens which consists of densely packed cones and
provides the clearest vision
Iris - The coloured part of the eye which consists of the radial and circular muscles which alter the size of
the pupil and control the amount of light entering the eye
Myopia – Short sightedness which usually results from an abnormally elongated eyeball
Presbyopia - A condition resulting from old age in which the lens loses its ability to change shape during
accommodation
Pupil - The hole in the iris of the eye through which light enters
Retina - A layer of light sensitive cells at the back of the eye on which images are formed
Rods - Rod shaped light sensitive cells found in the retina that work in dim light but do not respond to
differences in colour
Suspensory Ligaments - Fibers which hold the lens in position within the eye
Vitreous Humor - The jelly-like substance that fills and supports the chamber of the eye
Sclerotic Membrane - The outer membrane of the eye

THE EAR
Parts of the ossicles -
Malleus (the hammer), incus (the anvil), stapes (the stirrup)
Malleus - Hammer shaped bone which is connected to the incus and the eardrum. Its function is
to transmit vibrations from the eardrum to the incus
Incus - Anvil shaped bone which connects the malleus to the stapes transmitting vibrations
Stapes - Stirrup shaped
bone which is attached to
the incus and whose function
is to transmit
vibrations from the incus to
the membrane of the
inner ear

Functions of the Ear -


1. Used for hearing
2. Used to balance the body
3. Detects gravity and motion

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Ossicles - Small bones in the middle ear which amplify sound waves
Auditory Canal (Ear Canal) - Is a tube running from the outer ear to the middle ear
Cochlea - Auditory portion of the inner ear, it is the sensory organ of hearing
Eardrum (Tympanic Membrane) - Thin membrane that separates the external ear from the middle ear,
whose function is to transmit sound from the air to the ossicles inside the middle ear
Pinna (Auricle) - The visible part of the ear which is outside of the head
Eustachian Tube (Auditory Tube) - Is the tube that links the pharynx to the middle ear
Auditory Nerve (Cochlear Nerve) - The nerve that carries signals from the cochlea to the brain

THE SKIN
Functions of the Skin -
Prevention of water loss
prevention of damage of interior parts of the body
protection against radiation
vitamin D production
energy storage (fats)
detects touch stimuli
detects pain stimuli
Adipose Tissue (Body Fat) - Loose connective tissue composed of fats whose purpose is to store fat,
cushion and insulate the body
Sebaceous Gland - Microscopic glands of the skin which secrete an oil matter to lubricate the skin and
hair of mammals
Dermis - The layer of skin beneath the epidermis consisting of connective tissue, blood vessels, nerves,
hair roots and filled with fat
Malpighian Layer - A region of rapidly dividing cells beneath the epidermis of the skin which replaces
cells worn away from the skin surface
Sebaceous Gland - A gland in the hair follicles of the skin which secretes sebum which is an oily
substance that makes skin supple, waterproof and mildly antiseptic
Sweat Gland - A gland in the skin which produces water which evaporates into the air and cools the body

NOSE
Functions of the Nose -
-Detects chemicals in the air (sense of smell is dependent upon the concentrationof molecules in
the air)
-it is used with the tongue for tasting food

TONGUE
Functions of the Tongue -
Detects chemicals through four primary tastes (sweet, sour, salt and bitter)
Taste Bud - A collection of sensory nerve endings in the tongue which respond to certain chemicals in
food producing the sensation of taste

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DRUG ABUSE
Drugs - Are chemical substances that when taken will have psychological and physiological effects
Drug Abuse - Non medical use of a drug that interferes with health and productive life
Causes of Drug Abuse -
Social pressure
experimentation
escaping problems
poverty
employment (selling drugs)
Types of psychoactive drugs -
Stimulants - Drugs which stimulate or excite the nervous system, stimulating brain activity and
body processes (ex. cocaine, nicotine)
Sedatives - These are sleep-inducting drugs which slow down brain activities (Ex. alcohol,
valium)
Hallucinogens - Drugs which distort the way the brain interprets impulses from sensory organs
producing hallucinations (Ex. LSD, mushrooms)
Narcotics - Dull the senses and relieve pain by suppressing the cerebral cortex of the brain (ex.
heroin, opium)
Differentiate between drug addiction and drug tolerance -
Drug Addiction - The excessive use of drugs without consideration of their side effects and
without the ability to stop using them
Drug Tolerance - As a result of excessive use of a particular drug, a person requires large
amounts of a drug in order to get the effects of a small dose
Measures used to control drug abuse -
Avoid taking any drugs without a prescription from the doctor
avoid peer pressure to use drugs
avoid people who use drugs
inform the police if you see someone using drugs
engage in creative activities during leisure time
if you become addicted to drugs you should seek medical help
Ways to control drug addiction -
Choose friends who make good decisions
commit to not using drugs
avoid areas where drugs are present
work hard and focus on education
drug treatment programs
control supply through illegalization of drugs
discuss drug abuse
Effects of drug abuse on society -
Drug users resort to theft/prostitution/selling drugs,

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poor work performance


drug offenders crowd jails and the court system
Effects of drug abuse on individuals -
Legal and illegal drugs can have harmful effects (e.g. alcohol can damage the liver)
cocaine can cause high blood pressure
sharing needles can spread HIV/hepatitis
turning to crime to get money for drugs
malnutrition
Reasons drugs (inhibitory or antagonistic drugs) can temporarily stop pain after an injury -
They inhibit synaptic transmission so that impulses are not processed in the brain
stimulate cholinesterase which distort neurotransmitters signals
they also bind to receptors blocking the sensation of pain
Socioeconomic hazards of drug abuse -
Excessive spending on drugs means little is spent on basic necessities (i.e. food/clothing)
violence in families or community
poor work performance
loss of employment
dangerous roads due to intoxication from alcohol or drugs

HORMONES AND GLANDS


Enzymes used to break down proteins -
Pepsin -
Site of Production - Gastric gland in the stomach
Substrate - Protein
Product - Peptide
Trypsin -
Site of Production - Pancreatic gland
Substrate - Protein
Product - Peptide
Properties of enzymes -
They are proteins
specific to their functions
catalysts
activity is affected by pH/temperature/substrate concentration/enzyme concentration
they lower the activation energy of the reactions which they catalyze
possess active sites where the reaction takes place (sites have specific shapes)
they are very efficient (a small amount of catalyst can bring about a big change to the substrate)

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Enzymes found in the Human Gut which break down Carbohydrates –

Enzyme Site of production Substrate Product


Salivary Amylase Salivary glands Starch Maltose
Pancreatic Amylase Pancreas Starch Maltose

Secondary Sexual characteristics of Females -


Enlargement of mammary glands (breasts)
appearance of pubic hair under arm pits
experiencing monthly menstruation (bleeding)
high pitched voice
Secondary sexual characteristics of females are controlled by estrogen
Difference between Endocrine Glands and Exocrine Glands -
Endocrine Glands - Ductless glands which release hormones directly into the blood stream by
diffusion
Exocrine Glands - Glands with ducts which secrete their contents to the internal or external
surface of the body (ex. sweat glands, pancreas)
Hormone - A chemical produced in small amount in one part of the body which helps to coordinate
processes such as metabolism, growth and reproduction in other parts of the body
Properties of hormones (as a chemical messenger) -
Travels in the blood
small soluble organic molecule
effective in low concentrations
affects a site different from where it was made (target site)
fits precisely into a certain receptor like a key in a lock
specific to the target area
Functions of hormones -
Assuring that growth occurs properly
ensuring that development and maturation occur properly and on time
ensuring that reproduction occurs at the best possible time
Changes brought about by sex hormones -
Women - Widening of the hip girdle
Men - Deepening of the voice
Examples of hormones -
Follicle stimulating hormone (FSH)
lutenizing hormone (LH)
Adrenal corticotrophic hormone (ACTH)
growth hormone
FSH - Stimulates the development of a graafian follicle in the ovary
LH - Causes ovulation in females
ACTH - Stimulates the adrenal cortex to release adrenocortical hormones which control ionicbalance,
especially of sodium and potassium ions

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Growth Hormone - Stimulates the growth of tissues, especially muscles and the skeleton
Conditions associated with undersecretion or oversecretion of growth hormone -
Dwarfism - Results from undersecretion of the growth hormone at a young age
Gigantism - Results from the oversecretion of the growth hormone at a young age
Acromegaly - Results from the oversecretion of growth hormone in adults

Similarities between Nervous and Endocrine control -


-Both systems provide a means of communication and coordination within the body
-both involve the transmission of an impulse which is triggered by a stimulus which produces a
response
-target organs are similar to effector organs in that they give the response

Difference between Nervous and Endocrine Control –

NERVOUS CONTROL ENDOCRINE CONTROL


• Messages travel faster and have a rapid • Messages and transported slower and take
effect longer to take effect
• Usually a short lived response • Often a long lasting response
• Very localized as the impulse is transmitted • Effects are often widespread due to the hormone
to individual effector cells being carried through the body in the blood
•Relatively few neurotransmitters stream
(acetylcholine and adrenaline are most •Variety of hormones produced by different organs,
common) each with a specific effect
• Linked through the nervous system and • Linked through the blood and circulatory system
nerves
• Effectors are muscles and glands • Effectors are organs and the whole body
•Stimulated through receptors, eyes, nose • Stimulated through internal or external receptors
based on light,sound etc

Adrenalin - A hormone secreted by the adrenal glands which prepares the body for instant action by
increasing the heart rate, blood pressure and blood sugar levels
Endocrine System - A system of organs which produce hormones
Estrogen - The female sex hormone which controls conditions in the uterus before and during pregnancy
which is secreted by the ovary
Gland - A group of cells which manufacture and release enzymes or hormones in the body
Insulin - A hormone produced by the pancreas which helps control the amount of sugar in the blood
Islets of Langerhans - Regions of the pancreas containing endocrine cells which produce the hormone
insulin. A deficiency causes diabetes
Pancreas - An organ situated between the stomach and duodenum which produces insulin, trypsin,
amylase and lipase
Secretion - The production by glands of substances such as enzymes which are useful to the body
Testosterone - The male sex hormone which controls the growth of pubic hair, muscular development,
deepening of the voice. It is secreted in the testis of men

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Thyroid - An endocrine gland in the neck which produces a hormone called thyroxin which effects
physical and mental development. A deficiency causes dwarfism and mental retardation,
overproduction causes increased metabolism
Diabetes is associated with under-secretion of insulin in the blood

Tropic and Nastic Responses


Auxin - A hormone produced by plants which controls the rate of cell growth in roots and shoots and is
responsible for tropic responses
Hydrotropism - The growth movement in plants in response to water
Nastic Movements - Non-directional responses to stimuli (e.g. humidity, temperature)
Phototropism - Growth movement of a plant in response to the direction of light, plant moves towards
the light source
Tropism (Tropic Responses) - A movement in plants where the direction of the root and show growth
alters according to the direction of a stimulus
Geotropism - Growth movement of a plant in response to gravity, roots grow down and the stem grows
up

4. EXCRETION
Excretion - Removal from the body of waste produced by metabolism and excess substances from the
system
Faeces (Feces) - The indigestible material which remains in
the colon after digestion has taken place

EXCRETION IN HUMANS
URINARY SYSTEM
Urea - The main nitrogenous product excreted by a
mammal
Ureter - A tube which carries urine from a kidney to a
bladder
Urethra - A tube which carries urine out of the body as
well as allowing the passage of sperm
Urine - Liquid containing waste materials removed
from the blood by the kidneys which consists of
water/urea/minerals
Nitrogenous waste products removal with water -
Ammonia, uric acid
Ammonia - Requires a large amount of water to
excrete because it is toxic and soluble in water,
commonly excreted by aquatic organisms due to the high availability of water
Uric Acid - Requires less water because it is less toxic and less soluble in water, commonly excreted by
land organisms due to the low availability of water

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THE KIDNEY / WASTE REMOVAL


How the fluid in the proximal convolute tubule differs from that in the collecting duct in a nephron-
The proximal convolute tubule contains -
Glucose (this is where glucose is mainly reabsorbed), nutrients from food, minerals, amino
acids in greater amounts
The collecting duct contains -
No glucose, no food nutrients and others in less amounts
Effects of longer or shorter and the loops of Henle -
Longer - More water would be reabsorbed. This is an adaptation of many desert animals
Shorter - Less water would be reabsorbed

Why people do not urinate frequently on a hot day -


Mammals have different ways of reducing the amount of excess water in the body like sweating,
urination,breathing and defecation. Since it is hot the mammal will sweat meaning that there is
less excess water in the body to urinate
Processes involved in urine formation -
-Ultra filtration at the glomerulus
-reabsorption occurs at tubules
-secretionoccurs at the
second coiled tubule
Bowman’s Capsule - A cup-
shaped structure in a kidney which
contains a glomerulus and leads to
a kidney tubule
Proximal Convoluted Tubule -
The coiled part of the tubule next to
the Bowman’s capsule and is
located in the cortex
Distal Convoluted Tubule -
Coiled part next to the open end of
the tubule which joins with a
collecting duct
Glomerular Filtrate - A fluid which results from the filtration of blood in Bowman’s capsule. It consists of
urine and many useful substances such as glucose. Proteins and blood cells do not diffuse into it
Glomerulus - A group of capillaries inside a Bowman’s capsule in a kidney. Blood is filtered as it passes
through the glomerulus and Bowman’s capsule walls into the kidney tubule
Henle’s Loop - Portion of the nephron that leads from the proximal straight tubule to the distal convoluted
tubule
Kidney Tubule - A narrow tube leading form a Bowman’scapsule in the kidney which reabsorbs
water/glucose,Na+/Cland other useful substances from the glomerularfiltrate

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Nephron - The basic


structural unit of the
kidney whose function is
to regulate the
concentration of water
and soluble substances
by filtering the blood by
reabsorbing what is
useful and excreting
waste as urine
Renal Artery - The
artery that supplies
blood to the kidney
Renal Vein - The vein
that takes blood away
from the kidney

Complications and Disorders of the Excretory System


Nephritis - An infection or inflammation of the kidneys due to the failure of glomeruli to allow protein to
filter through into the tubules
Kidney Stones - Small stones that form in the pelvic region of the kidneys which can obstruct the flow of
urine
Cystitis - An inflammation of the bladder caused by an infection which causes frequent painful urination
Kidney Failure - A condition where one or both kidneys no longer function and can be fatal if untreated
Dialysis - The use of semi-permeable membrane to separate large molecules from small ones, used in
kidney dialysis machines to remove urea from blood

EXCRETION IN PLANTS
Transpiration - The process by which plants lose water in the form of vapour by evaporation
Importance of transpiration to plants -
-Brings a cooling effect to the plant when environmental emperatures are high
-water and minerals are drawn up from the soil solution up the plant in the transpiration stream
which are then used for photosynthesis
-regulates water levels in the plant
Harmful effects of transpiration -
Loss too much water due to transpiration can lead to wilting
serious desiccation
eventually death

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Factors affecting the rate of transpiration -


Environmental factors (temperature/wind/humidity/vapour/pressure/light/air movement)
leaf surface area and surface are to volume ratio, cuticles, stomata
number of stomata per unit of area

5. REGULATION
Regulation - The processes in an organism which keep levels of required conditions at appropriate levels
Homeostasis - Maintenance of constant internal environment
Homoeothermic (Warm blooded) Organisms - Organisms which are able to maintain a constant body
temperature
Poikilothermic (Cold blooded) Organisms - Organisms which cannot maintain a constant body
temperature and vary according to the temperature of their surroundings
Hydrocele - An accumulation of fluid in the body
Mechanisms which affect the internal environment of a body -
Breathing/gaseous exchange
temperature control
water and ionic control (excretion)
How water levels are kept constant in body fluids -
Too Low - When water levels fall as a result of dehydration, the hypothalamus is stimulated which signals
to the pituitary gland to secrete the hormone vasopressin to increase the permeability of distal
convoluted tubules resulting in more water being reabsorbed in the blood stream and osmotic
pressure is reduced to the optimal level
Too High - When water levels are too high it causes a reduction in the secretion of vasopressin from the
pituitary glad leading to a decrease in the permeability of the distal tubules resulting in less water
being absorbed and large volumes of water being excreted as dilute urine

TEMPERATURE REGULATION IN ANIMALS


Physiological activities which contribute to temperature regulation in mammals under -
Hot Conditions -
Vasodilation
reducing rate of metabolism
sweating
hairs lie flat to the skin surface
Cold Conditions -
Vasoconstriction
metabolism increased
hairs become erect
shivering occurs
Shivering - Shaking when an animal is cold. Its function is to generate heat when body temperature is
low

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Vasodilation - Refers to the widening of blood vessels resulting from the relaxation of smooth muscles in
the vessel walls
Vasoconstriction - Refers to the constricting of blood vessels resulting from the tightening of smooth
muscles in vessel walls
Poikilotherms - Animals which cannot control their internal temperature, so they must wait in the sun or
shade to regulate their temperature (ex lizards)
Homoiotherms - Animals which control their temperature by the actions of the hypothalamus in the brain
(ex humans)
Adaptations of Homoiotherms -
In cold environments -
Posses fat and fur
small ears and short noses to minimize surface area (to prevent heat loss)
hide in burrows or nests
hibernation (metabolic processes are reduced to a minimum)
migrating to warmer environments
In hot/dry environments -
Little fur or fat
large ears and long noses to maximize surface area
hide in nests during hot periods
aestivation (hibernation in hot, dry environmental conditions)
Methods used by mammals to lose heat -
Production of sweat
evaporation of saliva leading to panting
immersing their body in water to cool down
hair is lowered making a thinner coat which allows heat to escape more easily
molting occurs
metabolism decreases so that less heat is produced
Methods used by mammals to gain heat -
Decrease in production of sweat
jaws kept closed and breathing is slow through the nostrils to prevent evaporation of saliva
stays out of the water at night
thicker fur is grown
metabolism increases to produce more heat, shivering
A dog panting is an example of a cooling effect in hot conditions

Osmoregulation
Osmoregulation - The control of the movement of water in and out of the cells by osmosis
How glucose is kept at constant levels in body fluids -
Glucose is regulated by two hormones: insulin and glucagon
Too Low - When the level of blood sugar falls, it stimulates the release of glucagons which
convert glycogen into glucose, which increases blood sugar levels

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Too High - When the amount of glucose rises, the receptor centers for glucose are stimulated the
insulin is released to convert glucose into glycogen so that it can be stored in the liver

6. REPRODUCTION
Asexual Reproduction - Reproduction involving one parent, with the fusion of gametes
Sexual Reproduction - Reproduction involving two parents who produce gametes. These gametes fuse
together making a zygote which develops through an embryo stage to become a new organism
Binary Fission - The process of a parent cell splitting to become an independent organism (done by
ameba, paramecium and other bacteria)
Fertilization - The process of fusion between male and female gametes
Zygote - A fertilized Ovum which eventually develops into a new organism
Gametes - Male and female reproduction cells (eggs and sperm)
Hermaphrodite (Bisexual) - Occurs when an organism posses both male and female reproductive
structures

Difference between Asexual Reproduction and Sexual Reproduction –

ASEXUAL REPRODUCTION SEXUAL REPRODUCTION


• No genetic variation between offspring • There is genetic variation between offspring
• Requires one parent only • Usually requires two parents
• No gametes are involved • Involves fusion of two gametes

REPRODUCTION IN FLOWERING PLANTS


Anther - Terminal part of a stamen which produces and releases pollen
Stamens - The male reproductive organs of a flower. The anthers of stamens produce pollen grains,
consists of anthers and filament
Stigma - The part of the carpel where pollen grains become attached during pollination
Style - Surrounds the pollen tube of a plant, between the stigma and the ovary
Spore - A microscopic reproductive cell released from an organism during asexual reproduction
commonly found in fungi/mosses/ferns. For bacteria a spore is a resting or dormant stage of the
life cycle usually formed when conditions are unfavorable
Pollen - Male gametes of flowering plants
Pollination - Transfer of pollen grains from stamens to stigmas
Endosperm - The tissue produced under the seeds of flowering plants around the time of fertilization to
surround the embryo and provide nutrition
Germination - The transformation process of seeds turning into seedlings
Nectary - An organ in a flower that produces nectar and aids in pollination by attracting insects
Carpel - The female sex organ of a flower
Sepals - Leaf like structures at the outer region of a flower which protect the flower when it buds
Calyx - The collective name for the sepals of a flower
Coleoptile - Sheath-like protective covering over the first formed leaves of grasses and other cereals

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Pathenocarpic - Plants that can form a fruit without being fertilized (e.g. bananas)

REPRODUCTION IN MAMMALS
Human ovaries produce -
Ova, estrogen, progesterone

FEMALE REPRODUCTIVE SYSTEM


Uterus - A bag like organ of the female reproductive system which contains,protects and nourishes the
developing embryo
Cervix - The lower, narrow portion of the uterus
where it joins with the top end of the vagina.
During menstruation it opens slightly to allow the
endometrium to shed
Ovary - An organ which produces female
gametes (ova or ovules)
Fallopian Tube - The tubes which connect the
ovaries to the uterus
Endometrium - Inner membrane of the
mammalian uterus.
During menstruation it grows thick so that a
blastocyst can implant in the uterus
Blastocyst - The structure formed in the early
stage of mammals
Graafian Follicle - A fluid filled space in mammalian ovaries containing a cell which develops into a
female gamete (ovum)
Factors affecting Pregnancy in Females -
Releasing of ova in a normal monthly cycle
blocking or twisting of fallopian tubes
implantation of an embryo in the uterus
antibodies which destroy sperm

MALE REPRODUCTIVE SYSTEM


Prostate - An exocrine gland of the male reproductive system
Vas Deferens (Sperm Duct) -Transports sperm from the epididymis before ejaculations
Epididymus - Stores sperm and ejaculant
Testes - The male reproductive organ of animals which produce gametes called sperm and
testosterone
Gamete Formation and Fertilization
Ways a zygote differs from other cells in the body -
Has the ability to differentiate when it divides forming

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new cells that are specialized for MALE REPRODUCTIVE SESYTEM

different functions like tissues or


organs. The division of a zygote
leads to the formation of a
complete organism which grows
and develops to a stage where it
is able to reproduce
Zygote - The cell which results
from the fusion of a male and
female gamete (a fertilized egg)
Ovum (Ova) - Female gametes
of animals
Oviduct - A tube leading from a
funnel-shaped opening near an ovary to the outside of the body
Ovulation - The release of an ovum (egg cell) from a ripe graafian follicle
Ovule - The part of a carpel containing the female gamete or
egg nucleus. Ovules develop into seeds after fertilization
Menopause - The age at which women lose their ability to have children (infertility)
Menstruation - The breakdown and removal from the body of the lining of the uterus, which occurs if an
ovum has not been fertilized
Gametes - Cells involved in sexual reproduction i.e. pollen grain, ova. Gametes fuse together at
fertilization forming a zygote which develops into an embryo
Gametogenesis - Is a process by which diploid or haploid cells undergo cell division and differentiation to
form mature haploid gametes creating eggs or sperm
Semen - Fluid produced by the testes of mammals which consists of sperm and chemicals which nourish
them and stimulate their swimming movements
Sperm - The male gametes of animals
Gestation - A period of growth and development of a fetus in the uterus of a mammal
Embryo - The stage of development between the fertilized egg (zygote) and the newly formed organism
Factors affecting fertilization by males -
Few sperm produced in one ejaculation
a high proportion of sperm are abnormal

Disorders of the Reproductive System


Artificial Insemination - The process of introducing sperm at the time of ovulation which have been kept
frozen by liquid nitrogen
Test Tube Baby - A baby produced from an ovum fertilized outside its mother’s body then returned to her
womb to develop
Vasectomy - A surgical operation in which men are made sterile by cutting or blocking the sperm ducts
Hermaphrodite - An organism which possesses both male and female reproductive organs

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Fertility Drugs - Substances used to stimulate the development and release of ova from the ovaries of
women who are infertile because ovulation has stopped
Conditions affecting the Reproductive System -
Cancer
fibroids
prostate gland infection
impotence

Complications of the Reproductive System


Abortion - The termination of pregnancy by the removal or expulsion of a fetus or embryo from the uterus
resulting in its death
Still Birth - Occurs when a fetus has died in the uterus and the mother gives birth to the dead fetus,
generally happening after 20 weeks gestation
Miscarriage - Occurs when the embryo or fetus is incapable of surviving and dies, generally happening
prior to 24 weeks gestation
Ectopic Pregnancy - Occurs when pregnancy occurs outside of the uterus (in the fallopian tube) causing
internal bleeding of the mother and possibly her death
Non-communicable reproductive tract infections (RTIs) -
Gonorrhea, syphilis
Non-communicable reproductive tract diseases (RTDs) -
Urinary tract infection (UTI), candidiasis

SEXUALITY, SEXUAL HEALTH AND RESPONSIBLE SEXUAL BEHAVIOUR


Responsible Behaviours - Are actions which do not lead to health problems and require making good
decisions
Risky Behaviours - Actions or practices which lead to the development of health problems i.e. HIV
infection
Delaying Sex - An individual does not engage in sexual intercourse until they and their partner are ready
Advantages of abstaining from sex during adolescence - Eliminates risk of STDs, reduces risk of HIV
infection, avoids pregnancy, gives time to finish school
Assertive Behaviour - When someone stands for their rights no matter what the circumstances are
Importance of assertive behaviour -
Avoids unsafe sexual behavior
to avoid contracting HIV
avoiding drug use
avoiding early pregnancy
Passive Behaviour - When someone is silent and takes no action for their rights
Venereal Disease (VD) - A disease passed from one person to another during sexual intercourse e.g.
syphilis and gonorrhea
Ways to prevent infections of the reproductive system -
Use of condoms

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avoiding irresponsible sexual behavior


abstinence
faithful to one partner
Consequences of STD infections -
Death
deafness
blindness
hearth diseases
insanity
loss of economic productivity
Behaviours which lead to Risk of contracting STDs -
Drug/alcohol abuse
multiple sexual partners
prostitution
unprotected sex
Lead to Drug Abuse -
Peer pressure
choosing bad friends
laziness
stress or depression
Lead to Unplanned Pregnancies -
Premarital sex
unprotected sex
drug/alcohol use
prostitution
promiscuity
sexual abuse i.e. rape
social/cultural practices
Family Planning and Contraception
Family Planning - The planning of when to have children by using birth control, abstinence, fertility
management, education
Types of birth control -
Birth control pills
condoms sterilization
emergency contraceptive pill
rhythm method
abstinence abortion
use of spermicide
Maternal and child care
Prenatal Care - Care of a pregnant woman before delivery
Postnatal Care - Care of a woman after delivering a baby

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1. GROWTH
Types of Growth - Localized, diffuse
Diffuse Growth - Growth occurs all over the body, found in kingdom animalia
Localized Growth - Growth occurs in a certain region only, found in kingdom plantae
Factors influencing growth -
Access to food (carbohydrates, proteins, minerals, vitamins), water, light and temperature (plants)
growth hormone
genetic factors
diseases
accumulation of toxins in the body

MITOSIS AND GROWTH


Mitosis - Type of cell division resulting in cells with the same number of chromosomes as the parent cell,
type of division used when an organism grows or a colony of bacteria multiplies
Stages of Cell Division -
Prophase, metaphase, anaphase, telophase, interphase
Prophase - Is a stage of mitosis where the chromatin condenses into a chromosome
Diplotene - Stage of meiosis where the exchange
of genetic material takes place, occurs during
prophase I
Zygotene - Stage of meiosis where chromosomes
line up with each other in homologous pairs, occurs
during prophase I
Metaphase - The stage of mitosis where
chromosomes align in the middle of a cell before
being separated into each of the daughter cells
Anaphase - The stage of mitosis when
chromosomes separate. Each chromatid moves to
the opposite ends of the cell at opposite ends of the
mitotic spindle
Telophase - Is a stage of both meiosis and mitosis
where two daughter nuclei form in the cell as the
nuclear envelope forms around each pair of
chromatids
Interphase - The phase a cell spends the majority
of its time in. Most cell function is done during this
phase as well as preparation for cell division
Importance of Mitosis to Organisms -
Cell replacement

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growth
regeneration
asexual reproduction
genetic stability
Reasons meiosis is needed in the life cycle of sexually reproducing organisms
1. Brings about a reduction in the number
of chromosomes from diploid to haploid
during the formation of gametes. This
preserves chromosome numbers in the
species, since gametes must fuse during
fertilization forming diploid zygotes which
will contain the species character number
of chromosomes
2. Crossing over and independent
assortment of chromosomes during this
process brings about an exchange of
chromosomal material between
homologous chromosomes and also in the
genetic makeup of the offspring. Both
events lead to variations which natural
selection acts upon

Significance of Mitosis -
1. Can occur in damaged parts of an
organism to repair certain parts
2. Dividing cells carry hereditary materials
3.Growth occurs as a result of cells
dividing producing more and more cells

Significance of Meiosis -
Helps bring about a reduction in the number of chromosomes from diploid to haploid which is necessary
during fertilization when gametes must fuse, crossing over occurs during this process which brings about
an exchange of chromosomes which introduces variations in the genetic makeup of the offspring. Natural
selection acts upon these variations

Similarities between Mitosis and Meiosis -


DNA replicates once
involves nuclear division
they follow through the same steps (interphase, metaphase, anaphase, telophase)
paired homologues align at the metaphase

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Difference between Mitosis and Meiosis –

MITOSIS MEIOSIS
• One nuclear division • Two nuclear divisions
• Homologous chromosomes pair but do not • Homologous chromosomes pair and
undergo crossing over undergo crossing over during prophase I
• A single cell divides into two daughter cells • A single cell divides into four daughter cells
• The daughter cells are genetically identical to • The daughter cells are not genetically identical
each other and the parent cell to each other or the parent cells
• Daughter cells are diploid • Daughter cells are haploid

Analogous Chromosomes - Chromosomes with the same function but have different origins
Cancer - A disease in which fast growing abnormal cells invade and destroy healthy organs
Chromatid - One of the two identical strands of chromosomes, which separate during cell division and
moves to the opposite ends of the cell
Chromatin - Is the combination of DNA and proteins that makes up chromosomes
Crossing Over - A process during which meiosis where chromosomes exchange material with one
another. This increases the chances of variation within species
Diploid - A cell having the full number of chromosomes (e.g. organisms with paired chromosomes like
humans)
Haploid - A cell having half of the number of chromosomes created through meiosis
Heterozygous - The state of an individual which has different alleles in corresponding loci on a pair of
homologous chromosomes (i.e. Tt or Bb)
Homologous Chromosomes - The two chromosomes of each pair during meiosis which are identical in
shape and size
Meiosis - Type of cell division that produces gametes and results in cells with half the number of
chromosomes found in the parent cell
Recessive Characteristic -
One that does not appear in the phenotype when crossed with a dominant characteristic
Rapid mitotic cell division is seen in embryonic tissues
Chromosomes form pairs at the early stage of meiosis

GROWTH AND DEVELOPMENTAL STAGES IN HUMANS


Cultural practices affecting reproductive health in Tanzania -
Female Genital Mutilation - Surgical removal of the clitoris, labia minora, and labia majora from
a female for religious or ritualistic purposes which is often done as a part of initiation rites
Early Marriage - Marriage of women under 18 which can lead to delivery complications from lack
of physical development of the mother
Advantages of placental development for a developing fetus –
-Supplies food nutrients to fetus (e.g. glucose, amino acids, vitamins)

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-supplies oxygen/water/mineral salts


-removes waste from fetus
-protects fetus against the mother’s immune system and changes in mother’s blood
pressure
-provides physical attachment of the fetus to the wall of the uterus
Functions of the umbilical cord - Transports the following:
Food materials from the placenta to the embryo
oxygen from the placenta to the developing embryo
carbon dioxide from the embryo to the placenta (e.g. urea)
wastes from the embryo to the placenta
mineral salts from the placenta to the embryo
Substances which pass from the mother’s blood to the blood of the fetus -
Oxygen, food (e.g. glucose, amino acids), mineral salts, water
Possible consequences of Early Pregnancy -
Miscarriage
abortion
premature delivery
mother leaves school
financial and emotional stress
Birth control methods which suppress the formation or release of gametes -
Contraceptive pills (chemical method), sterilization
Prevent the implantation of a fertilized egg - Intrauterine devices
Prevent the union of gametes in fertilization -
Rhythm method (use of menstrual cycle calendar),
barrier method which involves the use of a condom,
diaphragm or female condom,
spermicides
Puberty - The stage of development where men and women become sexually mature and are able to
reproduce

PREGNANCY
Is the period during which a female mammal carries a developing embryo in her uterus
Placenta - The organ through which the fetus of a mammal obtains food and oxygen from its mother’s
blood and passes waste into the mothers blood
Umbilical Cord - A tube containing blood vessels connecting a developing embryo with its placenta
Fetus - The embryo of a mammal at the stage of development in which the mean features aren visible
Amniotic Fluid - Its function is to protect the developing embryo from physical damage as a kind of
shock absorber
Amnion - The fluid-filled sac that surrounds and protects embryos of reptiles, birds and mammals

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GROWTH IN FLOWERING PLANTS


Factors which cause difference in height among plants -
Light, water, soil fertility
Limiting factors for plant growth -
Nutrients, light, carbon dioxide, water

Germination Types -
1. Epigeal - Cotyledons are brought above theground along with the shoot
2. Hypogeal - Cotyledons remain below the surface of the soil and the shoot grows outward

Purpose of starch stored in beans to a developing plant -


It is used to release energy to the young plant when it undergoes anabolism which is used for
cellular activities like cell division
Factors required for the formation of carbohydrates in plants -
Sunlight, carbon dioxide, water, chlorophyll

STRUCTURE OF A SEED -
Cotyledon - After germination the cotyledon becomes the embryonic first leaves of a seedling
Hypocotyl - Part of the germinating seedling of a seed, which grows up with embryonic leaves
(cotyledons)
Radicle - Part of the seed which grows into the root system
Seed Coat (Testa) - Outer protective covering of a seed
Plumule - Consists of the first true leaves of a young plant
Coleorhiza - The cover on the radicle in a monocot seed
Coleoptile - The cover of a cotyledon in a monocot seed

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2. GENETICS
Alleles - One of a pair (or more) of alternative forms of a gene
Back Cross - The mating of a hybrid organism with one of its parents
Centromere - A part of a chromosome without genes which the chromosome uses to become attached to
the spindle
Chromosomes - Rod-like structures visible in the nucleus of a cell during cell division which consist
of genes and contain the hereditary information of the cell
Crossing Over - Is the exchange of genetic material between homologous chromosomes during
prophase I of meiosis (diplotene)
Dominant Gene - One which appears in the phenotype when crossed with a contrasting recessive
character
Gene - A part of a chromosome which controls the appearance of a set of hereditary characteristics
Genetics - The scientific study of genes
Genotype - The genetic makeup of an organism, the set of genes which it possesses
Heterozygous - Is when an organism has alleles (two genes) which control a characteristic and are
opposite in nature, the two alleles are different
Homozygous - When the two alleles are the same
Inbreeding - Is the reproduction from the mating of two genetically related parents which increases the
chances of the offspring being affected by recessive traits
Key - A sequence of statements about the characteristics of a group of organisms which can be used to
identify an organism belonging to that group
Mutation - A sudden unpredictable change in a gene or chromosome which alters its characteristics
Phenotype - The visible hereditary characteristics of an organism as opposed to the genotype which is
the genetic characteristics
Recessive - Refers to the trait or gene which cannot express itself due to the presence of a dominant trait
or gene. It is only expressed when it exists alone

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Recessive Gene - A gene which is not expressed when paired with a dominant gene, but can be
expressed if paired with another recessive gene. This can lead to genetic diseases
Segregation - The separation of genes which are called alleles of each other at meiosis and their
environment into separate gametes
Spindle - An arrangement of fibres between the poles of a cell which the chromatids (or chromosomes)
move during mitosis or meiosis
Test Cross - Is a test used to determine if an individual exhibiting a dominant trait is homozygous or
heterozygous for that trait
X Chromosome - A chromosome which when present in a zygote either along with another X
chromosome cause the zygote to develop into a female organism
Y Chromosome - A chromosome which when present in a zygote results in that zygote developing into a
male organism

GENETIC MATERIALS
Amino Acids - Organic compounds that consist of chemical units liked together in long chains to form
protein molecules, they separate from one another when the protein is digested
Differentiate between DNA and RNA -
DNA (Deoxyribonucleic Acid) - A chemical within chromosomes which contains the hereditary
information of the cell
RNA (Ribonucleic Acid) - A molecules which assists in the building of proteins, is formed by a
single helix, and is involved in the process of regulating which genes are expressed

CONCEPT OF INHERITANCE
Inheritance - The passing on of traits to offspring from parents or ancestors
Mendelian inheritance
Mendel’s First Law - Each of the two alleles of one gene may combine randomly with either of the alleles
of another gene independently
Bb - Heterozygous
BB - Homozygous dominant
bb - Homozygous recessive
Selective Breeding - Choosing to mate animals with desired characteristics so that future generations
will possess them (ex breeding cows for better milk or meat)
Monohybrid Cross - A cross between organisms which show contrast variations of only one
characteristic
P Generation - The parental generation. This is where the original genes come from
F1 Generation - The first filial generation. Organisms produced by crossing animals or plants which form
the starting point of genetic expression
F2 Generation - The second filial generation. Organisms produced by crossing or self crossing members
of an F1 generation

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1. In cattle the hornless trait is dominant and the horned trait is recessive. If a pure horned bull is mated
with a pure hornless cow, what kind of offspring are expected and it what ratio at the F1 and F2
generations?

F1 Generation

Gametes A A
a Aa Aa
a Aa Aa

In the F1 generation we can see that all offspring will be heterozygous horned condition Aa

F2 Generation

A a
A AA Aa
a Aa aa

In the F2 generation, we can see that the genotypic ratio is 1:2:1 between AA:Aa:aa. This means
that there will be 1 pure horned : 2 heterozygous horned : 1 hornless. The phenotypic ratio will be 3:1
meaning there will be 3 with the horned condition and 1 with the hornless condition

NON- MENDELIAN INHERITANCE


Complete Dominance - This is when a dominant gene is seen in the phenotype of an organism and the
recessive gene is not
Incomplete Dominance - This is when one gene does not completely dominate the phenotype of an
organism and a blending between the two traits occurs (ex a red flower gene and a white flower
gene combine to create a pink flower)

SEX DETERMINATION AND INHERITANCE


Sex Determination - Sex in humans is determined by chromosome pairs. XY is male, XX is female;
fertilization is a matter of chance i.e. whether the outcome will be XX or XY

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Sex Influenced Trait - Phenotype is caused when an allele is recessive in one sex but dominant in the
other
Sex Limited Character - Is a character which is restricted to one sex only (ex. baldness in males,
enlargement of breasts in women)
Sex-linked Characters - Characters carried in the X chromosome
Sex Linked Inheritance - Traits which are inherited together with the sex chromosome e.g. hemophilia
and colour blindness

Variation among organisms


Variation - Is any difference which exists between members which belong to the same species
Continuous Variations - Do not have clear cut differences (ex. height in a population)
Discontinuous Variations - Clear distinctions are present (ex. males/females, blood type)
Causes of variation - Genes and their properties

GENETIC DISORDERS
Mutagens - Factors that cause genetic mutation (ex gamma rays, chemicals)
Genetic Disorders -
Hemophilia - Impairs the body’s ability to control blood clotting (coagulation) to stop bleeding
Colour Blindness - The inability to see differences in colours that others are able to distinguish
Turner Syndrome - Occurs when all or part of one chromosome is absent causing physical
abnormalities like being short, swelling of the body, having a board chest, low hairline,
low ears
Down’s Syndrome (Mongoloid) - Occurs when there is all or part of an extra 21st chromosome

Application of Genetics
Biotechnology - The harnessing of biological processes to make useful substances, i.e. microbes that
can be used to make food/fuel/medicine/hormones
Genetic Engineering - A technique for altering an organisms genetic makeup by inserting a gene from
another organism into its chromosome

3. CLASSIFICATION OF LIVING THINGS


KINGDOM ANIMALIA
Characteristics of mammals (kingdom animalia) -
Presence of mammary glands
typically covered with hair
have internal fertilization
have a four chambered heart functioning as a double pump
possess well eveloped senses of smell and hearing. In 20% of mammal species
hearing is more important than vision
Examples of mammals -
Humans, bats, mice, lions, elephants

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Characteristics of Molluscs -
Unsegmented soft body often with a shell
large single muscular foot
Examples of Molluscs -
Snails, slugs, mussels, octopi
Differentiate between homologous and analogous structures -
Homologous Structures - Structures performing different functions but having the same or
similar origin (e.g. limbs can be used for swimming, flying, running or grasping)
Analogous Structures - Structures performing the same function but having a different
evolutionary history (e.g. bats and birds can fly with wings but they originated separately)

PHYLUM PLATYHELMINTHES
Characteristics of Platyhelminthes -
Flattened segmented worms
alimentary canal
but no mouth
body composed of three layers of cells
no body cavity
Examples of Platyhelminthes -
Planarians, flukes, tapeworms
Characteristics of Cestoda (kingdom animalia) -
-Possess hooks used for attachment in the gut to prevent being washed away by undigested food
materials
-possess suckers for attachment to the gut wall
-possess a cuticle with mucus to prevent digestion by the host’s enzymes
Examples of Cestoda - Tapeworms
Diseases caused by tapeworms or flukes -
Schistosomiasis (bilharzias), teniasis

PHYLUM ASCHELMINTHES (NEMATODA)


Characteristics of Nematodes -
Unsegmented worms
pointed at both ends
gut with mouth and anus
three layers of cells
many parasitic
Examples of Nematodes -
Hookworms, roundworms, threadworms
Diseases caused by nematodes -
encylcostomiasis (hookworm infection)

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PHYLUM ANNELIDA
Characteristics of Annelids -
Segmented worms
body composed of three layers of cells
but with mouth and anus
Examples of Annelids -
Earthworms, lugworms, ragworms, leeches

PHYLUM ARTHROPODA
Characteristics of Arthropoda -
Segmented body with a hard exoskeleton
jointed limbs segmentally arranged
three layers of cells
true body cavity
bilaterally symmetrical
Examples of Arthropoda -
Scorpions, spiders, millipedes, centipedes, cockroaches

TYPES OF METAMORPHOSIS
Complete Metamorphosis - A type of metamorphosis where an insect develops through four
stages
Egg larvae pupa adult. e.g. butterfly
Incomplete Metamorphosis - A type of metamorphosis where an insect develops through three
stages
egg nymph adult. e.g. cockroach

Antennae - Long, narrow sense organs on the heads of insects which contain receptors for touch, taste,
smell, humidity and temperature
Larva - An early stage in the life cycle of certain organisms which bears little or no resemblance to the
adult
Ecdysis - Shedding of the outer exoskeleton of an insect exposing the new soft exoskeleton e.g.
cockroach

Ways which insects are harmful or beneficial to man –

Beneficial to Man Harmful to Man


• Used as food • Pests destroy crops
• Tourism to view beautiful insects (colourful • Destruct human property
beetles) (timber/clothes/etc)
• Used in biological control of pests • Vectors of diseases
• Useful in recycling organic matter
• Production of fibres

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PHYLUM CHORDATA
Characteristics of Chordata -
Notochord present in adults
tubular
dorsal
hallow nerve cord
closed blood system
post-anal tail
Characteristics of Pisces (Fish) -
Paired fins
gills for gaseous exchange
external scales
lateral line system
Examples of Pisces -
Tilapia, carp, dagaa
Characteristics of Amphibia -
Paired limbs
gills present in tadpole stage
lungs in adult
soft skin
no scales
no outer ear
Examples of Amphibia -
Frogs, lizards, toads
Characteristics of Aves (Birds) -
Paired limbs
forelimbs are wings for flight
lungs for gaseous exchange
feathers on the body
eggs with a calcareous shell
no larval stage
warm blooded
Examples of Aves -
Eagle, heron, stork
Characteristics of Mammalia -
Paired limbs
lungs for gaseous exchange
sebaceous and sweat glands
hair
warm blooded
possess outer ear

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Examples of Mammalia -
Apes, humans, elephants, lions, mice, dogs, monkeys

4. EVOLUTION
Evolution - The sequence of gradual changes over millions of years in which new species arise

Theories of the Origin of Life


Natural Selection -
A theory which explains how evolutionary change occurred. It says that certain mutations of a
living organism allow it to compete for resources better than those without the mutation, meaning
that over a long period of time that characteristic will become dominant in the species and stay as
a part of their phenotype
Survival of the Fittest -
The statement that only organisms with the best characteristics will survive over a long period of
time, those with weaker characteristics will become extinct. This is partially true because animals
with weaker characteristics can still survive due to there being enough resources in the
environment, a lack of predators in the ecosystem or by filling a specific niche in the ecosystem

Theories of Organic Evolution


Lamarckism
The theory by Jean Baptiste de Lamarck which said that traits acquired by parents during their
lifetime where passed on to offspring. This has been proven to be incorrect
Weaknesses of Lamarckism -
Traits are not acquired during an animals lifetime, genetics has shown that genes determine the
characteristics of offspring
Darwinism
Theory proposed by Charles Darwin which states that new species arise as the result of genetic
changes over time which causes members of a species to no longer be capable of reproducing
with one another, creating two separate but genetically related species (ex. humans and apes
share the same common ancestor, however the ancestors split into two groups, one evolved into
humans, the other evolved into apes over the course of millions of years, man did not evolve
from apes)

EVIDENCE OF ORGANIC EVOLUTION


Anatomy - Groups of living animals resemble each other based on common ancestry
Embryology - There is a great deal of similarity during the development of embryos among widely
different animals (ex. all vertebrates share common features during embryonic development even
though in adult stages they are very different, like humans and birds)
Histology - Tissues and cells of related organisms are very similar
Biochemistry - The biochemical processes among all animals work the same as eukaryotic cells,
showing that animals developed from eukaryotic cells (ex cell respiration and the use of ATP)

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Genetics - Study of DNA clearly shows the genetic heritage which is shared by similar animals as well as
broadly among classes, phylums and kingdoms (ex mice and humans are genetically similar
even though they seem very different when you look at them. Their similar genotype means that
we can use mice to study diseases found in humans)
Paleontology - The study of animals and plants from millions of years ago shows that they were very
different than animals and plants today, yet they show a long term slow change in phenotype over
time towards animals and plants we see today, or showing lineages which no longer exist
Geography - This causes plants and animals to develop differently given different geographic locations.
For example marsupials and Australia carry their young in pouch, which is not done by similar
animals on other continents because they developed separately from the other groups

Charles Darwin Jean Baptiste de Lamarck

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