DON BOSCO COLLEGE

BASIC EDUCATION DEPARTMENT

Junior High School Level
Canlubang, Calamba City
S.Y. 2021-2022

Term: 2 Week: 3-4 Meeting: 1-3

Subject & Grade Level: Science 10
Topic: Homeostasis, Hormones, Central Dogma, Mutation,
Mechanism and Evidences of Evolution

WORKSHEET

DIRECTIONS:

1. This is an individual asynchronous seatwork.

2. In submitting or turning in your worksheet, save your file as PDF using the file name:
SURNAME_SCI_W3-4_M1-3(TASK_WS) eg. REYES_SCI_W3-4_M1-3(TASK_WS).

A. Analyze each statement. Write PF if it is Positive Feedback and NF if it is Negative Feedback.

_NF_1. The control of blood sugar (glucose) by insulin. When blood sugar rises, receptors in the body
sense a change. In turn, the control center (pancreas) secretes insulin into the blood effectively
lowering blood sugar levels.

_PF_2. Blood clotting. Once a vessel is damaged, platelets start to cling to the injured site and release
chemicals that attract more platelets. The platelets continue to pile up and release chemicals
until a clot is formed.

_NF_3. Temperature regulation in humans occurs constantly. When body temperature rises above this,
two mechanisms kick in the body begins to sweat, and vasodilation occurs to allow more of the
blood surface area to be exposed to the cooler external environment.

_PF_4. Production of human red blood cells (erythropoiesis). A decrease in oxygen is detected by the
kidneys and they secrete erythropoietin. This hormone stimulates the production of red blood
cells.

_NF_5. When a human is hungry, metabolism slows down to conserve energy and allow the human to
continue living with less food.

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 B. Analyze the problem sets below. Using the data, graph the corresponding figures [Always graph
time on the horizontal (X) axis. Label your axes], and answer the guide questions below.

Problem 1: A patient’s body temperature was recorded over a 24-hour period; the temperature
at each hour is listed in the table below. Graph the data in the space provided and state whether
it indicates negative or positive feedback.

98.90

98.80
98.70
98.60
98.50

98.40
98.30
98.10

12am 3am 6am 9am 12pm 3pm 6pm 9pm

Type of Feedback- ______Positive feedback_________________________________

Problem 2: A man with heart disease has his blood pressure monitored closely.

200
190

170
150
130
110
70

7am 8am 9am 10am 11am 12 noon 1 pm

Type of Feedback- _____________Negative Feedback____________________

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 C. The drawing below depicts the anatomical relationships between the hypothalamus and the
anterior and posterior lobes of the pituitary in a highly simplified way. First, identify each of the
structures listed below by color coding and coloring them on the diagram. Then, on the
appropriate lines write in the names of the hormones that influence each of the target organs
shown at the bottom of the diagram. Color the target organ diagrams as you like.

GH ACTH

Prolactin TSH

FSH

LH

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 D. The drawing below is a diagram of the various endocrine organs of the body. Next to each letter
on the diagram, write the name of the endocrine-producing organ (or area). Then select different
colors for each and color the corresponding organs in the illustration. To complete your
identification of the hormone-producing organs, name the organs (not illustrated) described in
items K and L.

Pineal Gland K. Small glands that ride

"horseback" on the thyroid

Anterior
pituitary
______Parathyroid Glands__________
posterior
pituitary
Thyroid

L. Endocrine-producing
organ present only in
Thymus pregnant women

Cortex

_______The Placenta______________
Medulla

Langerhans

Ovaries

Testes

E. For each of the following hormones, indicate the organ (or organ part) producing or releasing
the hormone by inserting the appropriate letters from Task D in the answer blanks.

____B____1. ACTH ____H____ 8. Glucagon ____K____ 15. PTH

____C____ 2. ADH ____H____ 9. Insulin ____B____ 16. GH

____G____ 3. Aldosterone ____B____ 10. LH ____J____ 17. Testosterone

____F____ 4. Cortisol ____A____ 11. Melatonin _____E____ 18. Thymosin

____G____ 5. Epinephrine ____C____ 12. Oxytocin ____D____ 19. Thyroxine

____I____ 6. Estrogen ____I____ 13. Progesterone _____B___ 20. TSH

____B____ 7. FSH ____B____ 14. Prolactin

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 F. Use the Venn Diagram below to compare and contrast DNA and RNA.
DNA RNA

Is a double Is a single
strand molecule strand molecule
Both important
in the human
Stable under
body Not stable
alkaline
conditions under alkaline
conditions

G. Transcribe the gene below into mRNA. Write you answer on the box

Sample
gene strand- CCTGGGATATAG
mRNA strand- GGACCCTATATC

* First 500 nucleotides (out of 29,811) of sequenced SARS-CoV-2 genome

ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCTGTT
CTCTAAACGAACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACG
CAGTATAATTAATAACTAATTACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGC
AGGCTGCTTACGGTTTCGTCCGTGTTGCAGCCGATCATCAGCACATCTAGGTTTCGTCCGG
GTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCCTGGTTTCAACGAGAAAACACACGTC
CAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGGAGACTCCG
TGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGA
AGTTGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGAT
GCTCGAACTGCACCTCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTC
AGTACGGTCGTAGTGGTGAGACACTTGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAG
TGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAATAAAGGAGCTGGTGGCCATAGTTA
CGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGA

UAAUUUCCAAAUAUGGAAGGGUCCAUUGUUUGGUUGGUUGAAAGCUAGAGAACAUCUAGACAAGA
GAUUUGCUUGAAAUUUUAGACACACCGACAGUGAGCCGACGUACGAAUCACGUGAGUGCGUCAUA
UUAAUUAUUGAUUAAUGACAGCAACUGUCCUGUGCUCAUUGAGCAGAUAGAAGACGUCCGACGAA
UGCCAAAGCAGGCACAACGUCGGCUAGUAGUCGUGUAGAUCCAAAGCAGGCCCACACUGGCUUU
CCAUUCUACCUCUCGGAACAGGGACCAAAGUUGCUCUUUUGUGUGCAGGUUGAGUCAAACGGAC
AAAAUGUCCAAGCGCUGCACGAGCAUGCACCGAAACCUCUGAGGCACCUCCUCCAGAAUAGUCUC
CGUGCAGUUGUAGAAUUUCUACCGUGAACACCGAAUCAUCUUCAACUUUUUCCGCAAAACGGAGU
UGAACUUGUCGGGAUACACAAGUAGUUUGCAAGCCUACGAGCUUGACGUGGAGUACCAGUACAA
UACCAACUCGACCAUCGUCUUGAGCUUCCGUAAGUCAUGCCAGCAUCACCACUCUGUGAACCACA
GGAACAGGGAGUACACCCGCUUUAUGGUCACCGAAUGGCGUUCCAAGAAGAAGCAUUCUUGCC
AUUAUUUCCUCGACCACCGGUAUCAAUGCCGCGGCUAGAUUUCAGUAAACUGAAUCCGCUGCUC
GAACCGUGACU

5|Page
 H. Write a short essay (at least 150 words) describing yourself (details about yourself, preferences,
habits etc.), then encode it in RNA coded format. Write your essay (alphabet format) on the first
box, and the encoded essay (RNA code format) on the second box.

Hello, my name is Lean Leopold A. Lasay and here are simple details that I do and my preferences that
build my personality. Details about myself, I am about 5’4 in height, about 50+ kilograms and personally
I think I am fit. I like food in general, I will just about eat anything but not bugs and insects. I dislike
minor inconveniences especially if they can be solved if done properly. MY habits are tucking my hand
under my pillow to sleep and using my forearm to rest my head to fall asleep. To wait a few hours after I
wake up to eat. I don’t like eating right away after I wake up. I like to watch racing sports like formula
one, I would watch it every Sunday. And my favorite team is Redbull racing, and my favorite driver is
Max Verstappen. And that is me, my habits, description, likes and dislikes.

GCAGAUUAGUAGACAUCGUGUCUGUCGGAGUGAUGUGAUUCGGACACUUCGUAGGAUUGAGA
GUCGUAGGAUACACUCACAUAGAUGUCGUGAUGCUCGUAGUGAACUUGACUGUCGUGAGAGAU
GUCGGCAGAUGUGGAUUCGUGAGUGGAUUCGACUGACUGUCUCUAGGAUUCGAUGGAUAUCU
GAGACUAGACUUCGAUCGCAUGAAUCUCGGACUCGAUGACAUCGUGAGAGAUGUCGUGUCUGU
CGCUCGUGGAUCGAGAUGUGGAUGAGAGUGAUACUUCGAUCGCAUGAAUCUCGGUACUAGACU
AGAUGUCGUGUCUGUCGCUCGAUGUGACUACAGAGUGAUAGGACAUCCUGUGCUCGAUGGAUA
UCUGAGACUAGACUUCGUGAGUAACACUAAUCUCGUGUCUGACUGAUUAGCGAUCGGACUCGU
GAUGUUCGUGAGUAACACUAAUCUCGGCGUCUUCGGACGAGUCGGCAGAUGACCAGGCAAUCU
CGUGAGUAACACUAAUCUCGGCGUAUUCGAGCGACUAGACACAGGUGUGAUGUACUUCGUGAG
AGAUGUCGCUCGAUGUGACUACAGAGUGAUAGUAGCUGUCGGACUCGAUCGCAGACGAGAGCU
CGGACUCGUGAUGUUCGCGAGACAUCUGCUCGGACUCGUAGGACAGCGAUUCGCGAACAACAA
UGUCGGACGAGUCGCAGGAUGAGGAUGUGUGAUAGUCGGACUCGUACGACUAGUAGUCGACG
CUAACUAUCUCGUGAGUAACACUAAUCUCGGAUUGAAUCUCGUGAGAGCUGAUCGCAGACGAG
CAGUCGGUACUAAUCUCGGAGACAAUCUCGGUACUACAGACUUCGUGAGAGAUGUCGGACGAG
ACUGAUAGUAUCACUUGCUCGGACUCGAUGGACACUUAGGACAGCGAUUCGUGUGACGAGACA
GUGUCGGACGAGAGUACAGAGCAUGAUGAGGACGAUGAGAGUGAUACUUCGGAUACUCUCGAU

6|Page
AGUGACUGAUAGUAGCUGUCGGACCGAUCGAUCGCAGAUCUGUCGAGUUGAGAGUCGGUAGA
UUCGACUACAUAGCAUGAUAUGUCGGACCGAUCGAUGACAGAGGAUUCGCUCGUGACACUCGA
UGUGUAGCUGUGCUCGUGUCUGUCGGCAUGAGUAGACAUCACUUCGUGAGUGGAUUCGAUCC
UAAGUAGCGACGAGCAGUCGUGUCUGUCGGCAUGAGAGAUGUCGCUAGAGAUGGAUGUGUCG
UGUCUGUCGCUCGACUAGUAGACAUACUCGAUCACAUCGACUUAGGAUGAUCUCUCGUGAGAG
AUGUCGCUAACUGACGAGCAGUCGUGUCUGUCGCGAACAGUGGAUUGAGUGUGUUCGAUCACA
UCGGUGGAUACUAUCUCGUGUCUGUCGGCAGAUUGAAUGUCGAUCACAUCGCGAUGAUAGUAG
UCGUGAACUUAGGAUGAUCUCUGCUCGAUCACAUCGUACUGAGACAUCUCGUGAUCGCGAGAU
UACUCGGCAACACUAGUGACUUCGUGACGAAUCGAUGUGUCGGACUCGUACUGAAGCGAUUCG
CUACUCUCGAUCACAUCGGAUUGAAUCUGCUCGGACUCGAUGACAGAGAUCUCGUAGGACAGC
GAUUCGGAUUGAAUCGACGAGCAGUCGGUGGACCAGGCAAUCUCGUGAUACUGACUGUCGUGA
CGAAUCGAUGUGUCGGACUCGUACUGAAGCGAUUCGCUACUCUGCUCGGACUCGUAGGACAGC
GAUUCGAUCACAUCGUACUGAAUCAGUGCAUCGGUGUGAAGUGACGAGCAGUCGACUCUCACA
GUGAUCACUUCGUAGGACAGCGAUUCGCGAACAGUGUGUCUAUAGUGAUCGACAGAGGAUUCG
GACUCGUACACACUAUAGAUGUCGUACUGAAUCAGUGCAUCGGACAUCUCGGAUCAUGAUGUG
CUGUCGACUCUAGAGAUGUGACUGUGCUCGUGAGAGAUGUCGUGUCUGUCGCGAUGACAUAC
AGUGGACAUCGAUUCGAUCGAUUGAUGUUCGGACACUUCGGUGGAUAUGGUACUAUAGUAGUC
GGUGUGAAGUGACGAGCAGUCGUGAGAGAUGUCGUGUCUGUCGCGAUGACAUACAGUGGACA
UCGAUUCGAUGGUGGACCAUGAUGUGUCGGACACUUCGUGUUGAUCAUCGCAUGAUGUGACUA
UCUGACUCCUCGAUGAGUGCUCGUGAGAGAUGUCGAUCGCAUGAAUCUCGGACACUUCGUGU
GAUUCGUGUCUGUCGGCAUGAGUAGACAUCACUUCGAUGGAUACUAGUGUGGACCUCAUCGAC
ACAGAGUCGUAGGACAGCGAUACUUCGUGAGAGAUGUCGAUGGACACUUAGGACAGCGAUACU
UGC

7|Page
 I. Analyze the genetic strands, and answer the questions below.

Answer the following questions below.

1. What happened to the “strand sentence” as it mutates?

As it mutates it the strand became shorter and little by little change the letters..

2. What are the changes made in each strand after it mutates?

The strand changes letters like T to R and changes the meaning of the strand.

3. Does the message in the original “strand sentence” still the same in each sentence.

No, because it changes as it mutates, and each change on the strand changes the meaning of the

original strand.

4. Locate the error/changes in each mutated strand sentence. (e.g. Strand 3, Base 1-T)

Strand 2 base 3 – R, Strand 3 base 4 – E, Strand 4 base 3 – R, Strand 4 base 7 – C.

5. What is the relationship of this activity to the changes in variation of organisms? Explain your
answer.

Like the activity as the strand mutates it changes subtlety but each mutation adds up until it become
completely different.

J. Read the situation below and identify the 5 points of Darwin’s natural selection.

“There are 2 types of worms: worms that eat at night (nocturnal) and worms that eat during the
day (diurnal). The birds eat during the day and seem to be eating ONLY the diurnal worms. The
nocturnal worms are in their burrows during this time. Each spring when the worms reproduce,
they have about 500 babies but only 100 of these 500 ever become old enough to reproduce.”

a.) What worm has natural selection selected:

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 AGAINST (Disadvantage)? _Diurnal worms_

FOR (Advantage)? _____Nocturnal________

b.) Identify the Darwin's 5 points in the scenario above.

Overpopulation
When the worm reproduce, they have 500 babies. __________________________________.

Struggle for Existence

From the 500 babies only 100 survive to grow old and reproduce. _______________________.

Presence of Variation
There are diurnal and nocturnal worms_____________________________________________.

Survival of the Fittest

There is a high chance that nocturnal worm survives because birds eat during the daytime____.

Variations Can Be Transmitted

Some of the nocturnal worm’s offspring can be nocturnal also___________________________.

K. Identify the organisms in each corresponding body part (forelimb) and its function.

Seal Bird Bat Horse Human

For swimming For flying For flying For running For grabbing

L. Write the letter of the correct definition in the blank space on the left.

___b___ 1. evolution a. relics or impressions of ancient organismsx

b. change through timex
___f___ 2. Theory of Natural Selection c. Father of Evolutionx
___c___ 3. Charles Darwin d. individuals of a given species varyx
e. antagonized by intelligent design
___h___ 4. Natural Selection f. common ancestry for all organismsx
g. organisms produce more offspring than can actually survivex
h. inherited characteristics that determines its chances of survival
9|Page i. different organisms, similar structuresx
j. post-anal tail and paired pharyngeal pouches
k. genes that determine their characteristics should have also x
changed
___g___ 5. overpopulation

___d___ 6. variation

___l___ 7. vestigial structures

___i___ 8. homologous structures

___k___ 9. DNA sequence

___j___ .10. embryology

M. Study the graphics, and answer the questions below.

What is the effect of resistant bacterium to the colony of bacteria?

The resistant bacterium survived when bathed in antibiotics. So, it got a chance to reproduce more.
And eventually transform the whole colony to a resistant kind.

N. Answer the question

“Do you think evolution on Earth has stopped? If not, do you think evolution will ever stop?”

No, I think evolution will keep going because like in basketball, men where smaller in height when

basketball first started. Now men are larger and taller playing. We are continuing to evolve if it benefits

us.

O. Write arguments about the resolve, “Evolution is the Guiding Light for Man’s Pursuit to the
Origin of Life” (Agree or Disagree).

I agree that evolution is the guiding light to the origin of life because it give us facts that we are
not the first kind of people. We have evolved continuously to have better chances of survival.
Know that we know that we can backtrack to study what the first of our kind is like.

P. Relate the natural selection principle, “Survival of the Fittest” to your life in the time of pandemic.
Write a brief reflection about it.

Survival of the fittest in this pandemic can be shown by people who are patient and people used
to being indoors having the upper advantage than the people who can’t wait and outdoorsy
people. Because they are used to being inside or can take not meeting people and have grown
accustomed to living in their homes. Rather than wanting to go outside all the time and risk
being infected by the virus

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