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GERD

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Gastroesophageal

Reflux
effortless retrograde movement of gastric contents
upward into the esophagus or oropharynx
Etiology and Epidemiology

• Physiologic GER (“spitting up”)

• Gastroesophageal reflux disease (GERD)


• Physiologic GER (“spitting up”)

✔ 8 to 12 months

✔ liquid diet

✔ horizontal body position

✔ short, narrow esophagus


✔ small, noncompliant stomach

✔ frequent, relatively large-volume


feedings

✔ immature lower esophageal


sphincter (LES)
• Gastroesophageal reflux disease (GERD)

✔ poor growth, pain, breathing difficulties

✔ only 5% in older children

✔ Decreasing the risk

• ante grade esophageal motility


• tonic contraction of LES

✔ Increasing the risk

• reduced tone of LES

• transient relaxations of LES

• hiatal hernia
• increased intra-abdominal
pressure

• cough

• respiratory difficulty (asthma or


cystic fibrosis)

• esophagitis(impairs esophageal
motility)
Clinical Manifestations
• Spits up

• Reswallowing

• Heartburn

• Cough

• Epigastric pain
• Dysphagia

• Wheezing

• Aspiration pneumonia

• Hoarse voice

• Failure to thrive
• Recurrent otitis media or sinusitis

• Anemia

• Hypoalbuminemia
Laboratory and Imaging
Studies
• Clinical diagnosis

• Barium upper G.I series


rule out gastric outlet obstruction, malrotation, or other
anatomic contributors

• 24-hour esophageal pH probe monitoring( Diagnostic)


uses a pH electrode placed transnasally into the distal
esophagus,

continuous recording of esophageal pH

data typically are gathered for 24 hours and analyzed for the
number and pattern of acid reflux events .
• Endoscopy
esophagitis, esophageal stricture, and anatomic
abnormalities
Treatment
• Healthy young infants - no treatment

• With complications

✔ H2 blocker

✔ proton-pump inhibitor

✔ Metoclopramide

• Fundoplication

• Jejunostomy(who cannot tolerate oral or gastric tube


feedings)
• Cessation of smoking

• Weight loss

• Not eating before bed or exercise

• Limiting intake of caffeine, carbonation, and high-fat foods


Thanks

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