Lactobacillus: Microbiology & Parasitology

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February 2022

MICROBIOLOGY &
CONMP-18
PARASITOLOGY

OBJECTIVES:
Lactobacillus Enumerate its basic

characteristics.
INTRODUCTION Check if it is gram negative or

positive.
Know the life cycle of

Lactobacilli are a type of Gram-


Lactobacillus.
positive bacteria found in nutrient-rich How lactobacillus infects.
environments such as those in foods,
feeds, plants, vertebrate and
invertebrate animals, and humans.
Lactobacillus is the largest genus
within the group of lactic acid bacteria.
These species are probiotics ("good"
bacteria) that helps the body break
down food, absorb nutrients, and fight
off disease-causing "bad" bacteria.
Lactobacillus is a nonmotile bacteria
that can live in both aerobic and
anaerobic conditions.

Beijerinck introduced the genus


Lactobacillus in 1901. Lactobacillus Lactobacillus is a vital organism known
species are common bacteria found in for its fermentative ability. During lactic
the mouth, gastrointestinal tract, and acid fermentations, they produce a
female genital tract, where they create variety of compounds such as organic
lactic acid (resulting in a low vaginal acids, diacetyl, hydrogen peroxide, and
pH) and compete with harmful Bacteriocin or bacterial proteins.
organisms for space. Lactobacillus Biopreservative refers to the use of lactic
species are often used as probiotics. acid bacteria and their metabolites to
improve microbiological safety and
extend the shelf life of foods.

They are a rod-shape bacteria or


coccobacilli and occasionally form short
chains. Although they require rich media
to grow, they are ubiquitous and may
survive anywhere there are
carbohydrates (e.g. food; respiratory,
gastrointestinal, and urogenital tract of
human and animals; sewage; and plant
material). They are non spore-forming
and lack motility. They are commonly
used to ferment food and as probiotics .
Lactobacillus
LIFE CYCLE

They reproduce asexually through


binary fission. The DNA in the parent
cell replicates, and attaches to different
sides of the cell membrane.
Cytokinesis happens next splitting
into two identical daughter cells.
However, they don't produce
endospores like other bacteria during
unfavorable conditions to survive.

HOW IT INFECTS

Lactobacillus can also cause severe


infections, especially in
immunocompromised patients
who have been in the hospital for
a long time. The most common
risk factors for Lactobacillus
infections are dental
manipulation, poor dental
hygiene, intravenous drug abuse,
abdominal surgery, colonoscopy,
probiotic use, and heavy dairy
product consumption.
REFERENCES :
Bratcher, D. (2018). Principles and Practice of Pediatric Infectious Diseases (Fifth Edition).
Rebbeca M. et. al. (2017, August). Lifestyles in transition: evolution and natural history of the

genus Lactobacillus, Pages S27–S48, https://doi.org/10.1093/femsre/fux030.

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