NAME OF THE DOSAGE, MECHANISM OF INDICATIONS CONTRAINDIC ADVERSE NURSING

DRUG FREQUENCY ACTION ATIONS EFFECTS/ RESPONSIBILITIES

AND ROUTE SIDE EFFECTS
Generic Name: Dosage: Decreases Is used to Contraindicated CNS: Before:
Ursodiol 300 mg cholesterol dissolve with allergy to Headache, 1. Verify doctor’s order.
(ursodeoxycholic content of bile (cholesterol) bile salts, dizziness, fever, 2. Determine if patient is
acid) Frequency: and bile stones gallstones and hepatic fatigue hypersensitive to the
BID by suppressing prevention of impairment, drug to prevent
Brand Name: cholesterol gallstone calcified stones, Respiratory: anaphylactic reaction.
Actigall Route: synthesis and formation in radiopaque cough, rhinitis. 3. Consider the 10 rights of
PO secretion from the obese patients stones or
medication.
Drug liver and inhibits experiencing radiolucent bile GI: Stomach
4. Inform the patient and
Classification:  intestinal rapid weight pigment stones, pain, nausea,
Gallstone- absorption of loss unremitting diarrhea, SO about the purpose of
solubilizing drug cholesterol.  acute constipation. the drug and likelihood of
cholecystitis, GI problems and other
cholangitis, Musculoskelet side effects
biliary al: back pain 5. Do not administer drug
obstruction, with aluminum-based
gallstone Derm: hair antacids. If such drugs are
pancreatitis, thinning, needed, administer 2–3
biliary GI fistula pruritus, rash hour after ursodiol.
(cholecystectom
y required). Other: Chills, During:
Body aches, or 6. Administer the
flu symptoms medication with meals,
unless otherwise directed
by the doctor.
7. Make sure that the
patient ingested the
given medication by not
leaving the room and
wait for the patient to
swallow the medication.

After:
8. Monitor the patient’s
response to the
medication.
9. Instruct patient and SO to
report severe or
 prolonged GI reactions
and other troublesome
side effects such as
severe or prolonged
headache, cough, nasal
irritation, or skin
reactions.
10. Document the
medication given and any
side effects on the
patient’s chart

NAME OF THE DOSAGE, MECHANISM OF INDICATIONS CLIENT’S NURSING RESPONSIBILITIES

 DRUG FREQUENCY ACTION RESPONSE
AND ROUTE
Generic Name: Dosage: Decreases Is used to dissolve Patient experienced Before:
Ursodiol 300 mg cholesterol (cholesterol) gallstones mild dizziness. 1. Verify doctor’s order.
(ursodeoxycholic content of bile and and prevention of 2. Determine if patient is
acid) Frequency: bile stones by gallstone formation in hypersensitive to the drug to
BID suppressing obese patients prevent anaphylactic reaction.
Brand Name: cholesterol experiencing rapid 3. Consider the 10 rights of
Actigall, Route: synthesis and weight loss medication.
PO secretion from the
4. Inform the patient and SO
Drug liver and inhibits
about the purpose of the drug
Classification:  intestinal
Gallstone- absorption of and likelihood of GI problems
solubilizing drug cholesterol.  and other side effects
5. Do not administer drug with
aluminum-based antacids. If
such drugs are needed,
administer 2–3 hour after
ursodiol.

During:
6. Administer the medication
with meals, unless otherwise
directed by the doctor.
7. Make sure that the patient
ingested the given medication
by not leaving the room and
wait for the patient to swallow
the medication.

After:
8. Monitor the patient’s response
to the medication.
9. Instruct patient and SO to
report severe or prolonged GI
reactions and other
troublesome side effects such
as severe or prolonged
headache, cough, nasal
irritation, or skin reactions.
10. Document the medication
 given and any side effects on
the patient’s chart

References:

 Ciccone C.D.(Ed.), (2016). Davis's Drug Guide for Rehabilitation Professionals. McGraw Hill. https://fadavispt.mhmedical.com/content.aspx?

bookid=1873&sectionid=139029534
 Ursodiol (ursodeoxycholic acid) Nursing Considerations & Management. (2022). RNpedia. https://www.rnpedia.com/nursing-notes/pharmacology-drug-study-not
NAME DOSAGE, MECHANIS INDICATIO CONTRAIN ADVERSE NURSING RESPONSIBILITIES
OF THE FREQUEN M OF NS DICATIONS EFFECTS/
DRUG CY AND ACTION SIDE
ROUTE EFFECTS
Generic Dosage: Polypeptide Is used to Hypersensiti Verify
Name: 1 mg hormone treat vity Gastrointestinal
Glucagon produced severe hypo disturbances
Frequenc by alpha glycemic (lo Pheochromo (nausea and
Brand y: cells of w blood cytoma (tum vomiting) and
Name: may repeat islets of sugar) or on possible ileus
GlucaGen q5–20 min Langerhans reactions the adrenal
if no . Stimulates which may gland) Tachycardia.
Drug response uptake of occur in
Classific for 1–2 amino acids patients Rebound
Insulinoma (t
ation:  more and their with diabete umor on the hypoglycemia
Hypoglyc doses conversion s mellitus (result of
pancreas,
emia to glucose treated insulin release
causing
Antidotes Route: precursors. with insulin.  excess and rebound
IM/SC/IV effect).
insulin)
Hypersensitivit
Glucagonom y reactions and
a (tumor on Anaphylaxis
the (rare reported
pancreas, in adults).
causing
excess Hypertension
production of and
the hormone hypotension
glucagon) (rare).

Hyponatremia
(variable
reports)
Before

11. Verify doctor’s order.

12. Determine if patient is hypersensitive to the drug to prevent anaphylactic reaction.
13. Consider the 10 rights of medication.
14. Inform the patient and SO about the purpose of the drug and likelihood of GI problems and other side effects
15. Do not administer drug with aluminum-based antacids. If such drugs are needed, administer 2–3 hr after ursodiol.

During:

16. Administer the medication with meals, unless otherwise directed by the doctor.
17. Make sure that the patient ingested the given medication by not leaving the room and wait for the patient to swallow the medication.
After:

18. Monitor the patient’s response to the medication.

19. Instruct patient and SO to report severe or prolonged GI reactions and other troublesome side effects such as severe or prolonged headache, cough,
nasal irritation, or skin reactions.
20. Document the medication given and any side effects on the patient’s chart

21. Schedule patients for periodic oral cholecystograms or ultrasonograms to evaluate drug effectiveness
22. Inform the patient or SO that he may need to continue taking the medication for several months;

Take home:

23. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time.
Do not double the dose to catch up.
24. Do not increase your dose or take this medication more often without your doctor's approval. Your condition will not improve any faster, and the risk of
serious side effects may be increased.

NAME OF DOSAGE, MECHANI INDICATIO CONTRAINDI ADVERSE NURSING

THE FREQUEN SM OF NS CATIONS EFFECTS/ RESPONSIBI
DRUG CY AND SIDE
 ROUTE ACTION EFFECTS LITIES

Generic Dosage: Polypeptid Is used to Hypersensitivit

Name: 1 mg e hormone treat y Gastrointest Verify doctor’s
Glucagon produced severe hypo inal order.
Frequency: by alpha glycemic (lo Pheochromocy disturbance
Brand may repeat cells of w blood toma (tumor s (nausea Monitor blood
Name: q5–20 min if islets of sugar) on the adrenal and glucose level
GlucaGen no Langerhan reactions gland) vomiting)
response s. which may and Determine if
Drug for 1–2 Stimulates occur in Insulinoma (tu possible the patient is
Classifica more doses uptake of patients mor on the ileus hypersensitive
tion:  amino with diabete pancreas, to the
Hypoglyce Route: acids and s mellitus Tachycardia medication to
causing
mia their treated . prevent
excess insulin)
Antidotes IM/SC/IV conversio with insulin.  anaphylactic
n to Rebound reaction.
Glucagonoma hypoglycem
glucose (tumor on the
precursors ia (result of Consider the
pancreas, insulin
. 10 rights of
causing release and medication.
excess rebound
production of effect). Inform the
the hormone relatives/family
glucagon) Hypersensit about the
ivity purpose of the
reactions drug and
and possible side
Anaphylaxis effects such as
(rare headache,
reported in nausea, and
adults). weakness.
Hypertensio After
n and administration
hypotension of medication,
(rare). observe
clinical
Hyponatrem conditions
ia (variable closely for
reports) signs of
hypoglycemia
and other
adverse
effects.

Be prepared to
give IV
glucose if the
patient fails to
respond to
glucagon.
Notify the
physician
immediately.

Notify
physician
promptly
whenever a
hypoglycemic
reaction
occurs so the
reason for the
reaction can
be determined

Monitor blood
glucose levels
and blood
pressure
regularly.

Document the
medication
given and any
side effects on
the patient’s
chart