Drug Calculation Worksheet

DRUG CALCULATION WORKSHEET
1. You are caring for a patient at home who must take magnesium
hydroxide/aluminum hydroxide (Maalox) 30 mL PO. How will you instruct the
patient to measure the dose using ordinary household measuring devices?
2. A patient has a bottle of warfarin (Coumadin) 5 mg tablets at home. After

his most recent international normalized ratio (INR), the doctor calls and tells
him to take 7.5 mg/day. How many tablets (scored) should the patient
take?
3. You have an IVPB of ranitidine (Zantac) 50 mg in 50 mL D5W to run over 30

minutes. The tubing has a drip factor of 15. How many drops per minute will
you set on the IV infusion controller?
4. The physician orders alprazolam (Xanax) 0.5 mg PO. You have on hand Xanax 0.25
mg tablets. How many tablet(s) will you give?
5. You need to administer 250 mg of erythromycin (Erythrocin) PO. You have on hand
0.5 g tablets. How many tablet(s) will you give?
6. You have available lorazepam (Ativan) 0.5 mg tablets, and you need to administer
1 mg PO. How many tablet(s) will you administer?
7. A patient with heart failure has a daily order for digoxin (Lanoxin) 0.25 mg PO.
Digoxin 0.125 mg tablets are available. How many tablet(s) should you give?
8. The physician writes a “now” order for codeine 45 mg IM for a patient with a
vertebral compression fracture. You have on hand codeine 60 mg/2 mL. How many
milliliters should you give?
9. You have on hand hydromorphone (Dilaudid) 4 mg/mL. You need to administer

0.015 mg/kg to a patient who weighs 150 pounds. How many milliliters should you
administer?
10. You have an order to administer 40 mg of methadone (Dolophine) SC for opioid

detoxification. You have on hand 30 mg/mL. How much should you draw into the
syringe?
11. A patient has a primary IV of dextrose in water 1,000 mL to be infused over 24

hours. What would be the drip rate (gtts/min) using tubing with a drop factor of
60?
12. Your patient needs 2,000 mL of saline IV over 4 hours for severely deficient fluid
volume. How many milliliters per hour will you set on a controller?
13. Your patient needs 2,000 mL of D5W IV over 24 hours, to be delivered with tubing
set with a drop factor of 15. How many drops per minute will you set for an infusion
rate?
14. You need to administer furosemide (Lasix) 2 mg/minute via continuous IV infusion
on a controller. Pharmacy has sent a bag of Lasix 400 mg diluted in D5W 250 mL.
How many milliliters per hour will you set on the controller?
15. The physician orders an IV with heparin at 700 units/hour. You have a bag with
100 units/mL of solution. How many milliliters per hour will you set on the IV
infusion controller?
16. A 12-year-old child was admitted to the emergency department because of an

asthma attack. Upon assessment, you found out that the child’s weight measures
82.4 lbs. The primary care provider ordered 2 mg/kg of methylprednisolone (Solu-
Medrol). The available stock dose is 125 mg/2mL. How many mL will the nurse
administer?
17. A health care provider orders amoxicillin syrup to a 3-year-old child with UTI.
Your assessment reveals the following data:
• Temperature of 38.5º C
• Heart rate of 88 bpm
• Respiratory rate of 30 bpm
• Blood pressure of 90/50
• Height of 98 cm
• Weight 12 kg (26.4 lbs)
The dosage required as per order is 50 mg/kg/day divided into 3 doses per day
(TID). Available stock is a suspension with a concentration of 400 mg/5mL. How
much will you administer per dose?
18. A patient with ventricular fibrillation is prescribed with bretylium 5

mcg/kg/minute. The medication comes mixed 50 mg in 50 mL of 0.9 % normal
saline. The patient’s weight is 170 lbs. How much of the medication will you
administer per hour?
19. A client suffering from chest discomfort and shortness of breath is brought to
the emergency department due to acute angina pectoris. The healthcare provider
orders IV nitroglycerin (Nitroglycerin) 75 mg in 500 mL of 5% Dextrose Water at
100 mcg/min. The nurse will set the pump at which rate (mL/hr)?
20. A primary healthcare provider ordered ceftriaxone (Rocephin) for a 4-year-old

child with lower respiratory tract infection. The dose required is 20 mg/kg/day
divided twice a day, administered per dose via IV. The child’s weight is 29 lbs. The
drug comes prediluted in a concentration of 10mg/ml. How much of the
medication will you administer in mL?
1. The doctor ordered Ampicillin sodium 150 mg IV every 6 hours. The medication label
reads 1g and reconstitute with 7.4 ml of bacteriostatic H20. How many ml will you need
to draw up for a dose?
2. A 25lb child was ordered Tylenol 115mg PO every 4 hours as needed for pain. How many
ml will you administer? (Tylenol 10mg/5ml)
3. You patient weighs 22kgs and you are ordered to infuse 250 mg dobutamine in 500ml
Normal Saline at 10mcg/kg/min. How many milligrams of dobutamine will you infuse per hour?
4. The order is 500mg of Rocephin to be taken by a 15.4lb infant every 8 hours. The
medication label shows that 75-150 mg/kg per day is appropriate dosage range. How much
will the patient receive per day? Is this within normal range?
5. The order is: Penicilling G 1.2 million units IM daily. Available: Penicillin G 9 million units/ml.
How many ml(s) will you give?
6. Doctor’s order: 2L of D51/2 Normal Saline with 50 mEq Potassium Chloride to infuse over
48 hours. Compute for the flow rate.

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DRUG CALCULATION WORKSHEET

2. A patient has a bottle of warfarin (Coumadin) 5 mg tablets at home. After

3. You have an IVPB of ranitidine (Zantac) 50 mg in 50 mL D5W to run over 30

9. You have on hand hydromorphone (Dilaudid) 4 mg/mL. You need to administer

10. You have an order to administer 40 mg of methadone (Dolophine) SC for opioid

11. A patient has a primary IV of dextrose in water 1,000 mL to be infused over 24

16. A 12-year-old child was admitted to the emergency department because of an

18. A patient with ventricular fibrillation is prescribed with bretylium 5

20. A primary healthcare provider ordered ceftriaxone (Rocephin) for a 4-year-old

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