Drug Study

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A Drug Study on

BUDESONIDE NEBULE

In Partial Fulfillment of the

Requirements in NCM 212 – RLE

OXYGENATION / FLUIDS & ELECTROLYTES

Submitted to:

Ms. Jackieline Lucero, RN


Clinical Instructor

Submitted by:

Jessa M. Villarosa, St.N.


BSN 3M – Group 5

August 19, 2021


Generic Name Budesonide

Brand Names Pulmicort Flex haler


Pulmicort Respules
Pulmicort Turbuhaler

Drug Classification Corticosteroid

Route of This medicine is used in a nebulizer. Nebulizers make a liquid into


Administration an aerosol that you breathe in through your mouth or your mouth
and nose into your lungs.
Mode of Action Budesonide is a corticosteroid with potent glucocorticoid action
that aids in the reduction of asthma-related inflammation and
hyper-reactivity (spasm) of the airways. When inhaled,
budesonide travels directly to the inner lining of inflamed airways
to exert its effects. It improves breathing in the lungs by reducing
airway inflammation and edema.

Dosage Initiation of therapy


Adults (12 years and older): Usually 1 - 2 mg twice daily.
In very severe cases the dosage may be increased further.
Children 3 months to 12 years: 0.5 – 1 mg twice daily.

Maintenance
Adults (12 years and older): 0.5 - 1mg twice daily.
Children 3 months to 12 years: 0.25 - 0.5 mg twice daily.

Indications Used to manage asthma in people who require continuous, long-


term therapy.
Contraindications It is not suitable as first-line therapy for status asthmaticus or
other acute episodes of asthma wherein intensive measures are
necessary. Contraindications include hypersensitivity to
budesonide or any of its components. Use cautiously in patients
with impaired liver function and severe pulmonary TB.

Drug Interaction Do not combine with other immune-suppressing medications


such as azathioprine, cyclosporine, cancer chemotherapy, or
mifepristone. Furthermore, certain medicines such as
ketoconazole, erythromycin, rifabutin, carbamazepine, and
phenytoin may interfere and eliminate budesonide out from the
body, which may affect how budesonide works.
Adverse and Side CNS: Headache, dizziness, lethargy, paresthesias, nervousness
Effects Dermatologic: Rash, edema, pruritus, alopecia.
GI: Nausea, dyspepsia, dry mouth.
Local: Nasal irritation, fungal infection.
Respiratory: Epistaxis, hoarseness, pharyngitis, cough.
Others: Chest pain, acne, bruising, back pain.

Nursing • Assess
Responsibilities ▪ Check the medical history of allergy. Observe for signs and
symptoms of anaphylaxis (rash, pruritus, laryngeal edema,
wheezing). Notify physician immediately if these problems
occur.
➢ Allergic reactions to medications can be minor and they
can also be very serious and life threatening, Nurses,
therefore, must assess patients and identify any possible
allergies to the medications.

▪ Encourage patient to complete full course of therapy.


➢ Budesonide is not intended for the treatment of acute
attack, therefore it will not provide an immediate relief so
full course of therapy is required.

▪ Observe for paradoxical bronchospasm (cough, wheezing,


dyspnea), especially at higher or excessive doses.
➢ If condition occurs, advise patient to withhold medication
and notify physician immediately.

▪ Monitor the patient for any sign of respiratory infection.


➢ Continued use of steroids during acute infection can lead
to serious complications related to the depression of the
inflammatory and immune responses.

▪ Instruct patient to avoid being around people who are sick or


who have infections such as chickenpox or measles while on
medication therapy.
➢ This medicine may weaken your immune system.
▪ Have the patient use decongestant drops before using the
inhaled steroid.
➢ To facilitate penetration of the drug if nasal congestion is
a problem.

▪ Have the patient rinse the mouth after using the inhaler.
➢ This will help to decrease systemic absorption and
decrease GI upset and nausea.
▪ Taper systemic steroids carefully during transfer to
inhalational steroids; deaths from adrenalin sufficiency have
occurred.

▪ Instruct patient to not mix budesonide suspension with


other medications in the nebulizer.

▪ Counsel patient on proper use of inhalation techniques


(nebulizer, powder inhalers, nasal sprays);
➢ Observe administration whenever possible to ensure
proper technique.
REFERENCES:
Budesonide Inhalation Suspension. (n.d.). Drugs.Com. Retrieved August 18, 2021, from

https://www.drugs.com/pro/budesonide-inhalation-suspension.html

Budesonide Inhalation: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD.

(n.d.). WebMD. Retrieved August 18, 2021, from https://www.webmd.com/drugs/2/drug-

75132-6245/budesonide-inhalation/budesonide-suspension-for-nebulizer-

inhalation/details

R. (2019, February 9). Budesonide Nursing Considerations & Management. RNpedia.

https://www.rnpedia.com/nursing-notes/pharmacology-drug-study-

notes/budesonide/?fbclid=IwAR3j3X04Dtl90GUmTLvOs56YiMm-

BBEY0w8FAPHw03tZEuQAQMp4LC7ZRb0

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