Dermatology 3

27/03/1444
BACTERIAL SKIN INFECTIONS
Dr. Hadaf Aljunaiyeh
OBJECTIVES
After completing this lecture, the student should be able to:

• Describe the morphology of common cutaneous bacterial
infections.
• Discuss the bacterial etiologies of cellulitis and erysipelas.
• Become familiar with superinfection of resident normal flora
• Recommend initial steps for the evaluation and treatment of
common cutaneous bacterial infections.
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NATURAL DEFENSE OF SKIN
1- Temperature more than 37cº

2- Dryness
3- Keratin & normal desquamation
4- Sebum with its low PH & high lipid content
5- Sweat with its low PH & high salt content
6- Skin associated lymphoid tissue
7- Resident microflora (mainly gram positive)
RESIDENT MICROFLORA
• Millions of micro organisms, reside harmlessly on skin

• The total microbial cell count in & on our
bodies is 10 times greater than the number of
human cells
• After the gut, there are more microorganisms on the
skin than anywhere else in the body
• Bacterial species are the most numerous
• Fungi, viruses & mites are also found on the normal skin
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RESIDENT MICROFLORA
• Resident flora are found in the upper parts of the epidermis &
congregated in and around the hair follicles.They include:
• Bacteria: Staphylococci, Micrococci, Diphtheroids: Corynebacterium,
& Brevibacterium
• Fungi: Candida albicans, Malasezzia & many other species
Staph.epidermidis+aerobic diphtheroids predominate on the surface,
Anaerobic diphtheroids deep in hair follicles
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TRANSIENT BACTERIA
• S. aureus does not normally reside on the skin, but

may be present transiently, inoculated from colonized
sites such as the nares(30%), axillae & vagina
• This colonization is usually
transient except in10-20%.
where it becomes persistent,
these are called staph carriers
& are a hazard to the society
PRIMARY BACTERIAL INFECTIONS
• Impetigo & ecthyma

• Folliculitis
• Furuncles & Carbuncles
• Erysipelas
• Cellulitis
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SECONDARY BACTERIAL INFECTION
Infection of previously damaged or diseased skin, such as

• Dermatitis
• Herpes simplex
• Burn
• Scabies & pediculosis
any child presenting with recurrent impetigo of the scalp we
should look for underlying pediculosis capitis.
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1100 × 786
IMPETIGO
• Acute, contagious bacterial infection of the skin

• Of 2 types:
• Bullous: caused by S. aureus
• Non-bullous: mainly by group A ℬ heamolytic streptococci
• Peak incidence aged 2-5 years, but can affect older children & adults
•♂ = ♀
• Can be primary or secondary
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NON- BULLOUS IMPETIGO
• Caused by strept., staph., or usually a mixture of 2

• A thin walled vesicle on erythematous base, soon ruptures & a crust
forms (yellowish brown= honey colored)
• Heals without scarring
• Regional adenitis & fever in severe cases
• Can affect any part, except palms & soles
• Mostly exposed parts, especially central face
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BULLOUS IMPETIGO
• Mostly caused by s. aureus

• Mostly in newborn
• Target area is the face, but can occur anywhere even palm & soles
• Bullae are larger, persist longer(2-3 days), contents are first clear
then become turbid, then rupture
forming thin varnish-like brownish crusts
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ECTHYMA
• A lesion of neglect, develops at site of old trauma

• Mostly elderly, diabetic, debilitated, or alcoholic
patients (= vagabond’s disease)
• Caused by strpt. pyogenes, & staph.
• Mostly on lower limbs
• Adherent crust, beneath which is a purulent irregular ulcer, delayed
healing with scarring.
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COMPLICATIONS
• lymphangitis, lymphadenitis.
• Staphylococcal scalded skin syndrome (SSSS).
• Post streptococcal acute glomerulonephritis,
especially in cases due to streptococcus pyogenes M
type 49
TREATMENT
• Wet compresses with antiseptic solution to remove crusts

with topical antibiotics is enough in mild cases.
If severe or a nephritogenic strain of strept is suspected;
then a systemic antibiotic is added as flucloxacillin ,
erythromycin or cephalexin.
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STAPHYLOCOCCAL INFECTIONS:
1- SUPERFICIAL FOLLICULITIS:
• Inflammatory disease of the hair follicles, which may be

infectious or non infectious
1- Infective: bacteria & yeast (pityrosporum)
2- Chemical: by mineral oils
3- Physical: as after hair epilation
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FOLLICULITIS
• The infection is superficial involving the ostium of the

hair follicle
• Usually caused by staph aureus
• Common on scalp of children, beard, axillae,
extremities, buttocks
• Heal spontaneously in 1 week, or become chronic
• In adults can progress to boils
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2- DEEP FOLLICULITIS(=FURUNCLES= BOILS)
• Staphylococcal infection of the hair follicles, similar to but deeper than

folliculitis
• Start as firm, red, tender papule that becomes painful & fluctuant
nodule, finally ruptures & discharges pus, leaving a scar
• Sites of friction & sweating; mostly neck, buttocks & ano-genital area
due to staph. carriage at these areas
• Constitutional symptoms may be present
• Some have recurrent attacks (=chronic furunculosis)
CHRONIC FURUNCULOSIS
• They may recur at intervals for no apparent cause, these patients

are staph carriers (they carry s. aureus in their nostrils, axillae &
groins)
• They may be treated by topical antibiotics applied to carrier sites
• Long courses of oral flucloxacillin
• Care about hygiene & predisposing factors
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CARBUNCLE
• Collection of boils
• Swollen suppurating painful areas discharging pus from several points
• In areas of thick inelastic skin the infection spreads to subcutaneous fat
such as nape of neck, back & thighs
• More painful & severe with constitutional symptoms
• More in diabetics
• Blood stream invasion may occur
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MANAGEMENT OF FOLLICULITIS
• Correction of underlying causes: diabetes, anemia, poor hygiene.

• Swabs for culture from lesions & carrier sites.
• Topical & systemic antibiotics.
• Incision of boils & carbuncle to speed healing.
• Recurrent boils need treatment of carrier states by b.d. topical
antibiotics for 6 weeks + improve patient’s hygiene.
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STREPTOCOCCAL INFECTIONS:
ERYSIPELAS & CELLULITIS
•Cellulitis: infection of the subcutaneous

tissue
•Erysipelas: infection of the dermis & upper
part of subcutaneous tissue
•by group A heamolytic strept.
ERYSIPELAS
• Port of entry is through minor cracks or wounds in the skin

• Starts with severe constitutional symptoms
• Followed by appearance of rapidly spreading painful erythematous
plaque with well defined margins.
• The surface may show hemorrhage or blistering
• 80% occur on the face
• Can be fatal if untreated
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CELLULITIS
Similar to erysipelas, with some differences

1- Deeper level of skin involvement (subcutaneous tissue)
2- Other organisms than strept. can cause it, like s. aureus
3- More raised & swollen but less well-defined border
4- More on the lower limbs than the face
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CELLULITIS
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COMPLICATIONS
1- Recurrences may lead to lymphedema

2- Subcutaneous abscess
3-Septicemia
4- Nephritis
TREATMENT
• Rest, analgesia
• Systemic antibiotics especially penincillin
E.g: benzyl penicillin 600 -1200 mg IV/6 hourly
Or cephalosporin
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ERYTHRASMA
• Caused by corynebacterium minutissimum a member of resident

flora
• Asymptomatic, well demarcated, scaly, reddish brown
• Body folds: axilla, groins, toe webs
• Coral red fluorescence with Wood’s lamp
• Treated by topical antifungal, antibiotics, or sometimes systemic
erythromycin
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CASE NO 10
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BACTERIAL
STAPH. STREPT. MIXED
SUPERFICIAL FOLLICULITIS ERYSIPELAS IMPETIGO
DEEP FURUNCLES & CELLULITES

CARBUNCLES
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27/03/1444

BACTERIAL SKIN INFECTIONS

Dr. Hadaf Aljunaiyeh

After completing this lecture, the student should be able to:

NATURAL DEFENSE OF SKIN

1- Temperature more than 37cº

• Millions of micro organisms, reside harmlessly on skin

• S. aureus does not normally reside on the skin, but

PRIMARY BACTERIAL INFECTIONS

• Impetigo & ecthyma

SECONDARY BACTERIAL INFECTION

Infection of previously damaged or diseased skin, such as

• Acute, contagious bacterial infection of the skin

NON- BULLOUS IMPETIGO

• Caused by strept., staph., or usually a mixture of 2

• Mostly caused by s. aureus

• A lesion of neglect, develops at site of old trauma

• Wet compresses with antiseptic solution to remove crusts

• Inflammatory disease of the hair follicles, which may be

• The infection is superficial involving the ostium of the

2- DEEP FOLLICULITIS(=FURUNCLES= BOILS)

• Staphylococcal infection of the hair follicles, similar to but deeper than

• They may recur at intervals for no apparent cause, these patients

• Correction of underlying causes: diabetes, anemia, poor hygiene.

•Cellulitis: infection of the subcutaneous

• Port of entry is through minor cracks or wounds in the skin

Similar to erysipelas, with some differences

1- Recurrences may lead to lymphedema

• Caused by corynebacterium minutissimum a member of resident

STAPH. STREPT. MIXED

SUPERFICIAL FOLLICULITIS ERYSIPELAS IMPETIGO

DEEP FURUNCLES & CELLULITES

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