Pulmnonary System

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PHYSIOLOGY OF THE

HUMAN RESPIRATORY SYSTEM

lek. Kamila Gorczyca


ORGANIZATION OF
BREATHING
INTERNAL RESPIRATION (-ssue respira-on)
Breathing involving the metabolism and energy in each cell.
It consists mainly in the transfer of electrons from hydrogen organic compounds to
molecular oxygen, leading to the forma-on of water.

O2 + 4 H ® 2 O2- + 4 H+ ® 2 H2O

The second oxida-on product – CO2 is formed mainly by decarboxyla-on of acids


Organic.

EXTERNAL RESPIRATION (gas exchange)


It consists in taking oxygen and giving away carbon dioxide.
Ven-la-on of the respiratory organs and exchange of gases between the blood in the
capillaries of the respiratory surface and the external environment of the body.
ORGANIZATION OF BREATHING
Respira-on (excluding from it all chemical transforma-ons in cells that take place in
them from the moment of O2 intake and co2 excre-on) are divided into stages:

1. VENTILATION of the respiratory organs

External
2. GAS EXCHANGE between the blood in the breathing
capillaries of the respiratory surface and the
external environment of the body

3. TRANSPORT OF GASES in the space between the surface Respiratory


respiratory in capillaries in -ssues blood func-on

4. GAS EXCHANGE between blood and fluid


intercellular through the wall of capillaries in -ssues with Internal
breathing
once between cells and surrounding -ssue fluid
EXCHANGE OF BREATHING GASES
EXCHANGE OF BREATHING GASES
The alveoli are made up of one layer of a very thin flat epithelium
EXCHANGE OF BREATHING GASES
EXCHANGE OF BREATHING GASES
The direc-on of movement of breathing gases is strictly determined by the decrease in
par-al pressures and the pressure of these gases

Atmosfera Płuca Krew Tkanki

O2 O2 O2 O2 O2
159 102 40 100 40

CO2 CO2 CO2 CO2 CO2


0,2 40 46 40 46

The rate and efficiency of respiratory gas exchange depends on:


par-al pressure difference
the size of the surface on which diffusion occurs
temperature at which the exchange takes place
pH at individual exchange points
EXCHANGE OF BREATHING GASES
LUNG VENTILATION MECHANISM
The lungs can change in volume with the chest, which becomes more capacious
when inhaling and less capacious when exhaling
LUNG VENTILATION MECHANISM

In the ver-cal direc-on, the dimension of the chest increases during the contrac-on of
the diaphragm

Transverse expansion of the chest involves li[ing the ribs, moving the sternum and
changing the shape of the spine. During a calm inhala-on, this happens under
the effect of spasm of the external and interchonal muscles.
LUNG VENTILATION MECHANISM
The en-re lungs are covered from the outside by a serous membrane called the
visceral pleura, which passes into the wall pleura lining the inside of the chest
Between them is a narrow space filled with a very small amount of serous fluid,
called the pleural cavity

WDECH WYDECH

The inner surface of the alveoli is covered with a molecular layer of SURFACTATANATE, which reduces
surface tension and prevents the alveoli from collapsing completely during exhalaAon
TYPES OF LUNG VOLUME AND CAPACITY
The lungs together with the airways are very stretchable and therefore do not have a constant
volume, but there are several typical types of air, capacity or volume
VOLUMES (V)
CAPACITY (C)
Elementary and indivisible components
Sum of relevant volumes
of the en-re lung capacity

Deepest breath

Calm inhala,on

Calm exhala,on

Deepest exhala,on

SPIROMETER is used to measure air volume


introduced into the lungs and removed from there during
different degrees of intensity of respiratory movements
RODZAJE OBJĘTOŚCI I POJEMNOŚCI
PŁUC
TV – breathing volume = volume of single breath (500 ml)
IRV – spare inspiratory volume (supplementary air) = the largest volume of air that
can be drawn into the lungs replenishing their filling from the top of a calm inhalaOon (2000 ml)
ERV – spare exhaust volume (spare air) = the largest volume of air that can be breathed out of the
lungs starOng at the end of a calm exhalaOon (1500 ml)
RV – residual volume (residual air) = volume of air in the lungs at the Ome of compleOon of the
deepest exhalaOon (1200 ml)
TLC – total lung capacity = volume of air in the lungs at the Ome of compleOon of the deepest
inhalaOon: IRV + TV + ERV + RV (5200 ml)
VC – vital capacity = volume of air that can be breathed out of the lungs in the space from the
deepest inhalaOon to the deepest exhalaOon: IRV + TV + ERV (4000 ml)
IC - inspiratory capacity (inhalaOon air) = the volume of air that can be drawn into the lungs starOng
from the peak of calm exhalaOon and ending with the top of the deepest inhalaOon : TV + IRV (2500
ml)
FRC – funcOonal residual capacity = volume of air contained in the lungs at the Ome of compleOon of
calm exhalaOon: ERV + RV (2700 ml)

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