STEM CELLS

TREATMENTS
SUMMARY
INTRODUCTION 04

AGING SKIN CARE - LIPO SKILL 05

WRINKLE FILLERS - LIPO SKILL 06

SCARS & STRETCH MARKS - LIPO SKILL PLUS 07

BODY SHAPING - LIPO SKIL PLUS 08

TAILOR MADE SKIN CARE 09

BODY AGING AND DEGENERATIVE PROCESS BY IV - LIFE SKILL 10

FEMALE REJUVENATION - LIPO SKILL 11

HAIR LOSS - HAIRSKILL 12

JOINTS OSTEOARTHRITIS - ORTHOSKILL 13

ERECTILE DYSFUNCTION & MEN SEXUAL HEALTH-ANDRO SKILL 14

PREMATURE OVARIAN FAILURE - OVOSKILL 15

SUPPORTIVE CARE 16

LUNG DISEASE 17

BIOSCIENCE TREATMENT PROCESS 18

BEST-CARE BY YOUR-CELLS
The degenerative aging of human tissue is a natural and physiological
process that can be accelerated as a result of environmental influences that
independently produce negative effects on the skin, mucosa and cartilage.
The ideal treatment should be regenerative, non-toxic, and made from natural
biological materials in order to produce natural, long-term and safe results.

ADSC ARE THE TOOLS THAT THE

NATURE HAD PROVIDED US

ETHICS AND SAFETY FIRST

Bioscience uses only autologous (i.e. collected from the patient himself) adult
cells, not embrionyc or fetal cells. The safety of use of such cells has been shown
in multiple scientific studies, published on the most relevant scientific journals
worldwide. Some of the trials covered a period of almost ten years and proved
that, once injected, the cells do not undergo any change or migration. The cells
are locally injected into the tissue, not the blood, of the patient from whom they
were originally extracted, thus ensuring the highest level of safety.

AUTOLOGOUS: COMPATIBLE WITH YOUR OWN BODY

Bioscience Clinic uses Adipose Derived Cells extracted your very own fat
tissue. The use is exclusively autologous, so each person is using only his own
cells. We know that the body can react unpredictably to any treatment
performed with foreign products. The only way to avoid this, is to use the
body’s own cells. The natural quality of the results obtained using your own
cells is incomparable.
 “Beauty
Beauty and Vitality
are gifts from nature for those
who live according to her laws”
(Leonardo da Vinci)
 Aging Skin Care
FACE, NECK, DÉCOLLETÉ AND HANDS

is a process that stimulates our personal supply of collagen-producing cells and

growth factors to reverse the effects of skin aging. It works by collecting a very small
amount of fat tissue, extracting the Adipose Derived Stem Cells and injecting them
directly into the skin tissue.

WHY LIPOSKILL ?
SKIN TEXTURE
Collagen is the key to smooth, wrinkle-free skin.
Children have perfect skin thanks to the higher
quantity of collagen that lies in their skin but as we
age we lose some of our collagen and develop
wrinkles. Collagen cannot be synthesized
artificially, it can only be produced by skin cells !

ADVANTAGES
LIPOSKILL is a natural method that does not rely INCREASING NUMBER OF
POSITIVE RESULTS
on injecting any artificial components into the
skin. Treatments such as Botox can reduce the
effect of wrinkles, but they cannot restore youth
to your skin. Botox will smooth out the wrinkles,
but still leave you with ‘old-looking’ skin, so we
recommended LIPOSKILL even before a Botox
Day 1 Day 30 Day 60 Years 4

treatment. 100 % 75,7 % 54,7 % 67 %

RESULTS
Initial results are visible in 2-3 weeks and the gradual
increase of the collagen and elastin are produced by
the natural activity of the implanted cells.
The reduction in the appearance of fine lines and the
improved skin texture are the most obvious results.
The skin looks smoother, healthier, and brighter.

WHAT TO EXPECT ?
Improvement of skin texture
The thickness of subcutaneous collagen improves
Fine wrinkles and other signs of aging disappear
Your skin will have an overall healthier and fresher look
 Wrinkle Filler
GLABELLAR AND NASOLABIAL FOLD, LATERAL BROW

is a wrinkle-filling product containing 100 % cells derived from one’s own fat. It can be
used anywhere in the body for a number of treatments, including filling both fine and
deep lines, as well as wrinkles. Following LIPOSKILL, the newly active cells go to work
causing a dynamic regeneration response at the cellular level while filling the wrinkles
caused by aging. The introduction of millions of powerful new cells into the skin allows
the replacement of lost volume with a natural, youthful-looking result.

ADVANTAGES
The difference between artificial fillers and LIPOSKILL is that wrinkles are filled exclusively
with one’s own cells and not with foreign, artificial components. The procedure restores the
youthful contour and shape of the face. It performs a dual action: increasing the volume,
and renewing the skin.

LONG LASTING RESULTS

LIPOSKILL is the only filler that lasts as cells life and therefore for several years.
Note: the effectiveness of the treatment is subject to genetics, skin condition, age and
lifestyle factors. For these reasons it will vary from individual to individual.





Before After 60 days

 
 

WHAT TO EXPECT ?
Fine and deep wrinkles disappear
Skin becomes brighter and more toned
Stable results without the need for further treatments
Natural and radiant looking
 Scars and Stretch Marks
ACNE AND DEPRESSED SCARS

Plus
through Adipose derived Stem Cells, it is able to reduce the deep acne scars and
stretch marks: they occur when the skin is overstretched. This sudden extension
causes a mark in the bottom layer of the skin that becomes noticeable. Scarring has
many causes from accidents to acne, surgery, illnesses such as chicken pox, and
countless other reasons.

WHY LIPOSKILL PLUS ?

LIPOSKILL PLUS is an advanced treatment that allow

the reduction of scars and stretch marks using
Adipose Derived Stem Cells. In both cases, the
injection of ADSC restores the physiologic condition
of normal skin repairing the damages through the
extracellular matrix rebuilt. In addition, the ADSC
remove the fibrotic tissue that reveal the scar making
it unpleasant in function and aesthetic.

WHAT TO EXPECT ?

The treatment helps your skin heal

properly without any scarring.
Gradual Decrease of wound scars.
Stretch marks can be reduced
to give the skin a clear and fresh
appearance.

RESULTS
ADSC help to rebuild new skin,
allowing skin lesions to progressively
fade and be replaced by fresh,
smooth skin.
The result is skin that looks healthy,
smooth and translucent.
 Body Shaping
BREAST AND BUTTOCK AUGMENTATION

Plus
can now be used for natural body shaping
treatments instead of using artificial
implants.
Many patients prefer the idea of using
their own Adipose Derived Cells instead of
introducing foreign materials into the body.
Using one’s own cells lowers the chances of
infection or other complications.
The procedure works by collecting a small
Body shaping for a natural
amount of fat, extracting and expanding
appearance and feel
Adipose Derived Stem Cells, and finally
using them for volume restoration and body
shaping.

LIPOSKILL PLUS ADVANTAGES

There is a dual aesthetic advantage as the patient can reduce fat volume in a specific
area (e.g. abdomen and thigh) and, at the same time, augment the volume in a
different area of the body such as the breasts or buttocks. Also it can be used to correct
asymmetries or damages caused by previous plastic surgeries and trauma.

RESULTS

The soft tissue augmentation with LIPOSKILL

Plus feels completely natural, no different
from your body. The tissue will have
the same kind of softness as its natural
counterpart, making it far more appealing
than an artificial implant. In the case of Day 0 After 4 years
breast augmentation treatment will typically
Bioscience patient, after 4 years, has more than 90% of
produce an increase of one or two cup sizes. the initial volume, as demonstrated by the MRI

WHAT TO EXPECT ?
Natural result (in appearance and feel) thanks to the use of your own body tissues
No surgery is needed for the injection, nor any prosthesis inside your body
All forms of diagnostic exams can be performed without any limits
It is possible to undergo additional treatments to further augment cup size
 Tailor Made Skin Care
OWN DERMO-COSMETIC GROWTH FACTORS

You can have a personalized cosmetic

product made from the powerful
components secreted by your own
Adipose Derived Stem Cells. It is your own
skin regenerative factors that stimulate the
skin’s natural healing abilities. ONLYOURS
is a tailor made cosmetic product which
boosts production of collagen and elastin.
This unique treatment helps to strengthen
the skin’s extracellular matrix effectively,
repairing the visible signs of aging.

dermo-cosmetic suite
Vaccine GF - 30ml
Dermo-cosmetic regenerative growth factors
from autologous adipose derived stem cells

GF 24 H Cream- 50ml
After Vaccine nourishing Pure Collagen

ADVANTAGES

• ONLYOURS is the only cosmetic product customized to

your skin’s genetic code
• The process is 100 % natural without foreign materials
• The skin’s own regenerative factors obtained from
your stem cells permit the rejuvenation of the skin.

WHAT TO EXPECT ?

Fresh, youthful skin appearance

Toned and supple skin texture
Repairs damage caused by smoking and sun exposure
Removal of fine wrinkles
 “Nature
never breaks her own laws”
(Leonardo da Vinci)
 BOOSTING POWER AND RESTORE BODY YOUTH

BODY AGING AND DEGENERATIVE PROCESS BY IV

A cutting-edge procedure to fight aging owing to your own stem cells.

Aging is a complex process associated with the reduction in the number of cells that allow
the organ and tissue regeneration.
The Anti-Aging IV treatment exploits the properties of these cells to fight the decay of
regenerative functions that begins to show itself already in middle age, with obvious signs
and symptoms (such as wrinkles and joint problems). However, not only that, the passing of
the years can also bring problems that endanger your health while remaining silent (such
as chronic low-grade inflammation);

ANTI-AGING IV LIFESKILL

THERAPY Anti-aging system power

Winning at aging to health living
Anti-Aging IV Therapy allows
you to fight aging in a totally Anti-Aging system -replace old cells with new ones

natural way, exploiting the Immune system – protection against infection and disease
regenerative capabilities of Cardiorespiratory – improves endurance and recovery
your mesenchymal stem cells,
Musculoskeletal system – increases strength and performance
the purpose is to enhance the
Circulatory system – Capillarity and elasticity of blood vessels
quality of lifestyle, increase
activity, and restore body Endocrine system – Hormones balancing

health.
 Female Rejuvenation
WHITENING DRYNESS, FLACCIDITY AND ATROPHY

for female rejuvenation is an innovative procedure for tissue

regeneration and to minimize the effects of dryness.
The elasticity of the tissues is related to the collagen and elastin
production by the cells of the same tissues. This treatment is
recommended for general ageing, pre and post menopause,
withering dryness, and the problems of flaccidity.

HOW DOES IT WORK ?

LIPOSKILL has a dual action thanks to cells and growth factors that cells produced.
The produced growth factors from injected cells, also, incite to the rejuvenation of
the existed tissues, reducing the withering dryness and flaccidity. Significant results will
appear 10-15 days after the treatment.

BE HAPPY AND ENJOY YOUR NEW LIFE!

WHY LIPOSKILL ?

LIPOSKILL is a source of regenerative factors which boosts the development of

soft tissues in our system improving our body’s response to biological damages.
LIPOSKILL enhances the repairing processes, the vascularization of the mucosa
and the synthesis of the collagen.
LIPOSKILL is essential to reduce the physiological ageing and improve tissues
regeneration and elasticity.
 Hair Loss
WEAKENING AND ANDROGENETIC ALOPECIA

is a very simple procedure that requires the collection of a small amount of adipose
tissue that can be harvested in a simple outpatient session. After twelve days the
ADSC, extracted from fat, are injected into the microenvironment surrounding
the hair bulb. The injected cells release specific growth factors that prolong
the duration of the anagen phase and improve the regeneration of the hair.

NATURAL WAYS TO
STRENGTHEN HAIR

WHAT TO EXPECT ?
With HAIRSKILLL it is now possible to treat progressive weakening of the hair bulb,
miniaturization of the hair and resulting hair loss. HAIRSKILL is an innovative, effective and
safe method, based on the use of stem cells derived from adipose tissue harvested from
the patients themselves.

RESULTS

Initial results are visible in 1 month and they gradually

increase over time. The adipose derived stem cells
therapy makes Hair Transplants easier because
it strengthens and prepares the scalp before the
transplant, and stimulates engraftment in the bulb.
It is a biological product and the results vary from
Before patient to patient according to biological age of
the patient.

RECOMMEND TO
The action of the ADSC is effective only if the bulb is not
irreversibly compromised.
This procedure is typically used for those patients who
are not surgical candidates because they are too
After 5 weeks
young, or are in the early phase of hair loss.
 Joints Osteoarthritis
CARTILAGE AND BONE DEGENERATION

is an innovative treatment for mild to medium bone and

cartilage degeneration. It uses the stem cells collected
from a patient’s own fat to treat the painful orthopedic
ailments of knees, hips, shoulders, ankles and other joints.
This treatment uses the regenerative components of your
body’s fat cells to repair the degenerative conditions
of bone and cartilage that may arise due to ageing or
trauma.

The procedure is very simple, and requires the

collection of a small amount of fat during an
outpatient procedure. Twelve days after fat
collection, ORTHOSKILL will be ready, and it will
perform the treatment with a simple injection in the
joint.

ADVANTAGES
ORTHOSKILL is a unique product that, when
injected straight into the joint, regenerates the cells
responsible for repairing the cartilage.

RESULTS
You can feel the results within days, although several weeks are necessary to begin to
see significant effects on your health or to feel your symptoms lessen.
Note: the quality of the biological product, and therefore its therapeutic efficacy, is
strictly correlated to the lifestyle and the physical condition of the patient (obesity,
smoking, alcohol and drugs will have a negative effect).

WHAT TO EXPECT ?
Repair damage to cartilage and bones resulting
from trauma or aging.
Rapid disappearance of the pain caused by aching
joints.
Faster healing and pain free movement.
Increased vitality 2-3 weeks after the treatment
(6 to 8 weeks for a more complicated intervention).
 Erectile Dysfunction
& Men Sexual Health

Erectile Dysfunction is one of the most frequently reported medical condition in men.
Defined as the chronic inability to achieve or sustain the erection, its prevalence varies
across age group, with 35% and 50% ca of men, respectively, aged 60 and older than
70 affected. However, it is not a natural part of getting older. Erectile dysfunction not
only could be a sign of a health problem (such as blood vessels clogging or nerve
damage) but also it could severely compromise man’s quality of life (leaving him
with low self-esteem, lack of self-confidence, and poor-quality intimate life) and his
partner’s mental, emotional, and physical wellbeing, ultimately leading to the risk of
marital relation problems.

WHY
Treat causes and not only the synptoms

Curative for medium and severe erectile dysfunction

Totally safe and stable results

Effective and longlasting results

Androskill uses hundereds of million of expanded stem cells and not few thousands that are
obtained from SVF (Stromal Vascular Fraction)

STEM CELL THERAPY

acts via regeneration of nerves and blood vessels, inflammation reduction, healing
promotion and other specific mechanisms still to be fully characterized. It is delivered
through intracavernosal injection of Adipose Derived Stem Cells (MSCs), a type of stem
cells capable of self-renewal and of differentiating into multiple cell types. Stem cell
therapy tolerability and safety have been demonstrated and the use of autologous stem
cells mitigates any immunogenic concerns.
Their efficacy in the treatment of erectile dysfunction has been demonstrated too.

ACTION
Nerve regeneration
Decreased apoptosis of cavernosal cells

smooth muscle preservation

vascular endothelial regeneration

Increased cavernous smooth muscle

and endothelial content

decreased collagen and fibrosis

 Premature Ovarian Failure

Ovaries usually produce hormones and eggs until the early fifties, when they stop
working and most women enter menopause. However, in some cases women can
enter early menopause because of Premature Ovarian Failure (POF), a common
gynecological endocrine disease also known as primary ovarian insufficiency.

ADIPOSE DERIVED STEM

CELLS THERAPY
OvoSkill, the stem cell therapy for premature ovarian Reducing level of FSH
failure is based on the collection of only 20 cc of fat
Elevating level of E2
during a quick and painless outpatient procedure.
Repair damaged ovarian function
Bioscience Laboratories receive the collected fat
Promoting formation of follicles
and expand the isolated stem cells in only two weeks,
obtaining several hundred million of pure autologous Improvement of ovarian weight
cells that can be used for ovarian failure treatment High IVF success rate
as well as for other procedures. The cells that are not Resuming of mestruation
immediately utilized are frozen and cryopreserved for
Totally safe and stable results
future treatment; cells are preserved for a minimum
of two years, ready to be thawed for additional use.
OvoSkill it is delivered through intra-ovarian injection
of autologous Adipose Derived Stem cells (ADSCs),
a type of stem cells capable of self-renewal and
of differentiating into multiple cell types. Stem cell
therapy tolerability and safety have been plenty
demonstrated and the use of autologous stem cells
mitigate any immunogenic concerns. Their efficacy
in the treatment of premature ovarian failure has
been demonstrated too.

STEM CELLS ACTION

differentiation into granulosa and stromal cells

balance the reproductive ovarian physiology

secretion of angiogenic GF, vascular endothelial GF, placental GF, trasforming GF β

secretion of anti-inflammatory cytokine

reduction of germ and stroma cells apoptosis

enhancement of the maturation of the ovarian follicle

anti-fibrotic and angiogenic effect
 Supportive Care
IMMUNE DISORDERS

Rheumatoid arthritis Chronic inflammatory demyelinating polyneuropathy

Psoriasis
Systemic lupus erythematosus
Hashimoto’s thyroiditis
Inflammatory bowel disease Myasthenia graves
Guillain-Barre syndrome Vasculitis

DIABETIC THERAPY SUPPORT

BENEFICIAL ACTIONS

Protect and prevent remaining β-cells from dying Induce autophagy activity 
Promote beta-cell function  Prevent metabolic hormone resistance
Regulating of the immune system Encourage existing cells to self-repair
Reduce inflammation Encourage existing cells to adapt

POTENTINAL RESULTS

Significant decreased inflammatory markers such as C-Reactive Protein

Measurable improvement in kidney function of a decrease in creatinine levels
Improved capacity for physical activities
An increased feeling of vitality with improved energy levels
Reduced risk of complications
Loss of neuropathy
Loss of pruritus
Loss of Nocturia
Increase limbs vascularization
An increased libido
 Lung Disease
ASTHMA
is an incurable illness of the airways.
The disease causes inflammation and
narrowing inside the lung, restricting air
supply. The symptoms of asthma often
present in periodic attacks or episodes
of tightness in the chest, wheezing,
breathlessness, and coughing.

CHRONIC OBSTRUCTIVE PULMONARY

DISEASE (COPD)

is a progressive disease. The airways of the

lungs become inflamed, making them
narrow. They can become clogged with
mucus, which is produced more than normal
in COPD.
This makes it difficult to get air in and out
of the lungs, and can lead to breathing
difficulties. 

EMPHYSEM A
is a type of chronic obstructive pulmonary
disease (COPD). It involves the loss of
elasticity and enlargement of the air sacs
in the lung. The alveoli at the end of the
bronchioles of the lung become enlarged
because their walls break down or the air
sacs are destroyed, narrowed, collapsed,
stretched, or over-inflated.
Having fewer and larger damaged sacs
means there is a reduced surface area for
the exchange of oxygen into the blood and
carbon dioxide out of it.
 from Lab to Clinics

Sampling
20cc of fat is collected in
the course of an outpatient
procedure (quick and
painless).

Thawing Extraction
The cryopreserved Bioscience Laboratories
vials can be used receive the collected fat.
for additional
treatments. Step Within 12 days the
extracted cells are
expanded.

by
Step
Banking Expansion
The remaining vials are frozen The laboratory produces
and cryopreserved 20 vials of cells that
for 3 years. can be used to perform
different treatments.

Treatment
The vials can either be used
to perform an immediate
treatment, or they can be
stored for future
treatments.

QUALITY: THE PRIORITY OF BIOSCIENCE

The Regenerative Medicine Centers, based in San Marino-Europe and Dubai-
Middle East, offer the most unique and exclusive therapy. All the procedures
of cell extraction and expansion in the Middle East are carried out at the
Bioscience laboratories located in Dubai Healthcare City (DHCC).
The development of the laboratories in Dubai made full use of the eight years
of experience that Bioscience Institute Laboratories already had in Europe.
Anyone wishing to check the quality of the Bioscience laboratories can visit
the website www.bioinst.ae and evaluate the standards of environmental and
instrumental operating procedures by observing the procedures via webcam
in real time.
 bioscience
i n s t i t u t e

SAN MARINO DUBAI

Strada Rovereta, 42 Al Razi Building n.64 - Block B
47891 Falciano RSM Dubai HealthCare City - UAE

Phone +971 (0) 4 375 7220

info@bioinst.com - www.bioinst.com

QUALITY
TOP

MEDICINE
NETWORK

Dubai - Republic of San Marino - Milan - Rome