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    Protocol For Treatment of Anaphylactic Reactions

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    buena
    Epinephrine is the first line treatment for anaphylaxis and should be administered intramuscularly or subcutaneously for mild symptoms. For more severe cases, additional therapies like IV epinephrine, oxygen, IV fluids, and transport to the hospital are needed. Diphenhydramine is also used to treat symptoms. All patients experiencing anaphylaxis should be observed for several hours, with more severe cases observed for up to 24 hours.

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    Protocol For Treatment of Anaphylactic Reactions

    Uploaded by

    buena
    23 views1 page
    Epinephrine is the first line treatment for anaphylaxis and should be administered intramuscularly or subcutaneously for mild symptoms. For more severe cases, additional therapies like IV epinephrine, oxygen, IV fluids, and transport to the hospital are needed. Diphenhydramine is also used to treat symptoms. All patients experiencing anaphylaxis should be observed for several hours, with more severe cases observed for up to 24 hours.

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    Protocol for Treatment of Anaphylactic Reactions

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    Epinephrine is the first line treatment for anaphylaxis and should be administered intramuscularly or subcutaneously for mild symptoms. For more severe cases, additional therapies like IV epinephrine, oxygen, IV fluids, and transport to the hospital are needed. Diphenhydramine is also used to treat symptoms. All patients experiencing anaphylaxis should be observed for several hours, with more severe cases observed for up to 24 hours.

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    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    23 views1 page

    Protocol For Treatment of Anaphylactic Reactions

    Uploaded by

    buena
    Epinephrine is the first line treatment for anaphylaxis and should be administered intramuscularly or subcutaneously for mild symptoms. For more severe cases, additional therapies like IV epinephrine, oxygen, IV fluids, and transport to the hospital are needed. Diphenhydramine is also used to treat symptoms. All patients experiencing anaphylaxis should be observed for several hours, with more severe cases observed for up to 24 hours.

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    PROTOCOL FOR TREATMENT OF ANAPHYLACTIC REACTIONS

    All personnel administering biologic products or serum should be prepared to recognize


    and treat anaphylaxis.

     Mild symptoms of pruritus, erythema, urticaria and angioedema should be treated with
    epinephrine injected intramuscularly or subcutaneously, followed by diphenhydramine,
    hydroxyzine or other anti-histamine given orally or parenterally. Epinephrine
    administration may be repeated every 5-15 minutes. If the patient’s condition improves
    with this management and remains stable, a long-acting epinephrine injection may be
    given and an oral anti-histamine prescribed for the next 24 hours.

    Treatment of more severe or potentially life-threatening severe anaphylaxis involving severe


    bronchospasm, laryngeal edema, shock and cardiovascular collapse necessitates additional
    therapy. Maintenance of the airway and oxygen administration should be instituted promptly.
    IV epinephrine may be indicated. Rapid IV infusion of physiologic saline to maintain blood
    pressure must be instituted to compensate for the loss of circulating blood volume that may
    occur. Patients manifesting with severe anaphylaxis should be immediately brought to a
    hospital setting for treatment and additional management.EPINEPHRINE IN THE
    TREATMENT OF ANAPHYLAXIS
    Subcutaneous or Intramuscular administration
    Epinephrine 1:1000 (aqueous) in 1mg/ml ampoule: 0.01ml/kg per dose repeated every
    10-20 minutes.
     Infants : 0.05-0.1ml
     Children : 0.1-0.3ml
     Adolescents : 0.3-0.5ml
    Intravenous administration
    Epinephrine 1:1000 (aqueous): 0.1ml/kg diluted to 1:10,000 with physiologic saline.
     Dose may be repeated every 10-20 minutes. A continuous infusion should be
    started if repeated doses are required. One milligram (1 ml) of 1:1000 dilution of
    epinephrine added to 250ml of 5% dextrose in water, resulting in a concentration
    on 4ug/ml, is infused initially at a rate of 0.1 ug/kg per minute and increased
    gradually to 1.5 ug/kg per minute to maintain blood pressure.
    DIPHENHYDRAMINE IN THE TREATMENT OF ANAPHYLAXIS
    Oral, IM or IV (50mg/ml)
    1-2 mg/kg every 4-6 hours (100 mg maximum single dose)

    All patients showing signs and symptoms of anaphylaxis, regardless of severity, should
    be observed for several hours. A period of observation of 4 hours would be reasonable for mild
    episodes and perhaps as long as 24 hours for severe episodes.

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