PENGARUH NANOEMULSI JAHE MERAH (Zingiber officinale var Rubrum) SEBAGAI ANTI

HIPERTENSI YANG
DIAPLIKASIKAN PADA TIKUS (Sprague dawley) MODEL LIGASI URETER
NADA HANIFAH, Prof. Dr. drh. Siti Isrina Oktavia Salasia
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

DAFTAR PUSTAKA

Akinyemi, A. J., Ademiluyi, A. O., dan Oboh, G. 2014. Aqueous extracts of two
varieties of ginger (Zingiber officinale) inhibit angiotensin converting
enzyme, iron(ii), and sodium nitroprusside-induced lipid peroxidation in
the rat heart in vitro. Journal of Medical Food 16(7) :641–646.

Anonim. 2011. Biopharmaceutical classification system and formulation

development. Particle Sciences Drug Development Services.

Bhattarai, S., Van Tran H., dan Duke, C.C. 2001. The stability of gingerol and
shogaol in aqueous solutions. Journal of Pharmaceutical Science, 90(10),
1658–1664.

Cunningham, J. G dan Klein, B. G. 2007. Veterinary physiology fourth editio

Missouri: Elsevier. 443–444.
Ghayur, M. N dan Ghilani, A. H. 2005. Ginger lowers blood pressure through
blockade of voltage-dependent calcium channels. Journal Cardiovasc
Pharmacol 45 :74–80.
Guerrero, L., Castillo, J., Mar, Q., Vallve, S. G., Arola, L., Pujadas, G., dan
Muguerza. 2012. Inhibition of Angiotensin-Converting Enzyme Activity by
Flavonoids: Structure-Activity Relationship Studies. Plos One 7(11):1–11.
Gupta, A., Eral, H.B., Hatton, T. A., dan Doyle, P. S. 2016. Nanoemulsions:
formation, properties and applications soft matter. The Royal Society of
Chemistry 12: 2826–2841.
Guyton, A. C dan Hall, J. E. 2006. Textbook of Medical Physiology, Eleventh
Edition. Pensylvania: Elsevier. 223–227.
Handayani, V., Ahmad, A. R., dan Sudir, M. 2016. Uji Aktivitas Antioksidan
Ekstrak Metanol Bunga dan Daun Patikala (Etlingera elatior (Jack)
R.M.Sm) Menggunakan Metode DPPH. Pharm Sci 1(2): 86–93.
Harmilah dan Ekwantini, R. D. 2014. Jus Seledri (Apium Graveolens)
Menurunkan Tekanan Darah Tikus Rattus Strain Wistar Dengan
Hipertensi. Jurnal Teknologi Kesehatan. (10): 28–34.
Hau, J., Gerald, L., dan Hoosier, V. 2003. Handbook of laboratory animal science
second edition volume II. New York: CRC Press.
Katzung, B. G. 2001. Basic & Clinical Pharmacology, Eight Edition. Mc Graw Hill
Companny. P: 270.

26
 PENGARUH NANOEMULSI JAHE MERAH (Zingiber officinale var Rubrum) SEBAGAI ANTI
HIPERTENSI YANG 27
DIAPLIKASIKAN PADA TIKUS (Sprague dawley) MODEL LIGASI URETER
NADA HANIFAH, Prof. Dr. drh. Siti Isrina Oktavia Salasia
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

Kumar, R. dan Soni, G. C. 2017. Formulation development and evaluation of

Telmisartan Nanoemulsion. Prajapati International Journal of Research
and Development in Pharmacy & Life Science, 4(6): 2711–2719.
Kwon, E. K., Lee, D. Y., Lee, H., Kim, D. O., Baek, N. I., Kim, Y. E., Kim, H. Y.
2010. Flavonoids from the buds of Rosa damascena inhibit the activity of
3-hydroxy-methylglutaryl-coenzyme a reductase and angiotensin I-
converting enzyme. Journal Agric Food Chem 58 (2): 882–6.
Liu, Q., Liu, J., Guo, H., Sun, S., Wang, S., Zhang, Y., Li, S., dan Qiao,
Y. 2013. 6- Gingerol: a novel AT1 antagonist for the treatment of
cardiovascular disease. Planta Med 79: 322–326
Malkoff, J. 2011. Non-invasive Blood Pressure for Rats. Anim Lab News. 1– 12.
Mazzaferro, E. M. 2010. Small Animal Emergency and Critical Care. Blackwell
Publishing: USA. P: 355.
Mukkavilli, R., Yang, C., Tanwar, R. S., Ghareeb, A., Luthra, L., dan Aneja R.
2017. Absorption, Metabolic stability, and pharmacokinetics of ginger
phytochemicals. Molecules (22): 553–554.
National Heart Foundation of Australia. 2016. Guideline for the diagnosis and
management of hypertension in adults. Melbourne: National Heart
Foundation of Australia.
Ngantung E C, Deiske A S, and Robert A B. 2016. Uji aktivitas antibakteri dari
spons Dictyonella funicularis dan Phyllospongia lamellose yang diambil
pada perairan Bunaken. Jurnal Pesisir dan Laut Tropis 2(1): 10–16.
Ojeda D, Jiménez-Ferrer E, Zamilpa A, Herrera-Arellano A, Tortoriello J, Alvarez
L. 2010. Inhibition of angiotensin converting enzyme (ACE) activity by
the anthocyanins delphinidin- and cyanidin3-O-sambubiosides from
Hibiscus sabdariffa. Journal Ethnopharmacol 127(1):7–10.
Pratoko, D. K., Wardhani, F.A., Kristiningrum, A., Fajri, F.A., dan
Pangaribowo, D. A. 2018. Kadar Fenolat dan Flavonoid Total serta
Kapasitas Antioksidan Ekstrak Etanol dan Fraksi Jahe Merah
(Zingiber officinale var. Rubrum). Al Kimia 6(2): 166–172
Puri, S. T., Shakaib, M. I., Chang, A., Mathew, L., Olayinka, O., Minto., Sarav.,
Hack, K., dan Ouig, R. J. 2010. Chronic kidney disease induced in mice by
reversible unilateral ureteral obstruction is dependent on genetic
background. Am Journal Physiol Renal Physiol (298): 1024–1032.
Riskesdas. 2018. Hasil Utama Riset Kesehatan Dasar 2018. Kementerian
Kesehatan Badan Penelitian dan Pengembangan Kesehatan: Jakarta. hal:61.
Setiawan. 2015. Budidaya Jahu. Pustaka Baru Press: Yogyakarta.
Setyaninrum, H. D dan Saparinto, C. 2013. Jahe. Bogor: Penebar Swadaya.
 PENGARUH NANOEMULSI JAHE MERAH (Zingiber officinale var Rubrum) SEBAGAI ANTI
HIPERTENSI YANG 28
DIAPLIKASIKAN PADA TIKUS (Sprague dawley) MODEL LIGASI URETER
NADA HANIFAH, Prof. Dr. drh. Siti Isrina Oktavia Salasia
Universitas Gadjah Mada, 2019 | Diunduh dari http://etd.repository.ugm.ac.id/

Shaban, M. I., Gahsh, N. F. A., dan El-Sol, A. E. H. 2017. Ginger: it's effect on
blood pressure among hypertensive patiens. Journal of Nursing and
Health Science 6(5): 79–86.
Syahrini, E. N., Susanto, H. S., dan Udiyono, A. 2012. Faktor-faktor risiko
hipertensi primer Puskesmas Tlogosari Kulon Kota Semarang. Jurnal
Kesehatan Masyarakat 1(2): 315–325.
Stankovic, M. S. 2011. Total phenolic content, flavonoid concentration and
antioxidant activity of Marrubium L. extracts. Kragujevac Journal Sci
(33):63–72
Widyaningrum, S. A. 2015. Formulasi Dan Uji Aktivitas Antimikroba Nanoemulsi
Minyak Manis-Jangan (Cinnamomum burmanni Nees ex. BI.) terhadap
Pseudomonas aeruginosaNCTC 12924 dan Staphylococcus aureus ATCC
29213. Thesis. Universias Gadjah Mada.