Migut

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L A U N C H E S

A Kit Based Microbiome Gut Test Performed on NGS


for Accurate Health Assessment
D SENSITIVITIES
FOO
ES
In a leaky- gut, food
C
EN
S particles & toxins pass I
UE directly into the blood
TR

U
stream, causing

N
S
IS

OF
inflammation
L
CA

throughout the body

ON
Poor gut health has been
GI

TI
associated with central
OLO

P
nervous system diseases

S OR
such as Parkinson’s A leaky & inflamed gut
NEUR

disease, Alzheimer’s leads to poor absorption


of nutrients &

P O OR A B
disease, Autism, Multiple
sclerosis & neuromyelitis elimination of waste
optica Indications
of Poor
Dysbiosis of gut health Gut Health
has been associated with
onset of Type 2 Diabetes Poor digestive function

ASE
through decreased can be the start of most
glucose tolerance & inflammatory process &
DI A

ISE
insulin resistance autoimmune diseases

ED
BE

Dysbiosis of gut health

UN
TE

leads to release of
cytokines, causing

M
S

IM
anxiety, depression,
mood swings & panic T

O
attacks AU

ME
NTAL S
HEALTH ISSUE

What can a Gut Test tell you?

Gut microbiome diversity Intestinal permeability

Bacteria, fungi, parasites


Gut inflammation
& viruses in the gut flora

Nutrients absorption
Did You Know
With compromised digestion our
bodies under-produce
neurotransmitters, like serotonin
attributed to anxiety, depression,
About 70% of the and other mental health issues
immune system is
housed in the gut

Enough sleep helps


lower cortisol levels
Taking some time to and allows time for
meditate can help the gut to repair itself
ease symptoms of
stress-induced gut
disorders

Benefits of Test at Lupin Diagnostics

Performed on NGS for


Accurate Gut Health
Assessment results

Offers Individualised Gut


Microbiome Composition

Provides Individualised
Dietary Recommendations
Patient’s Personalised miGUT HEALTH kit

Test Table
Test Code Test Name Sample Type Lab Cut-Off TAT

Stool sample collected


in container placed in
personalised kit Daily 10:00 am
LDMOL2645 MIGUT HEALTH 4-6 weeks
(Read sample collection
intsructions manual
placed in kit)

References

1. Li D, Gao C, Zhang F, Yang R, Lan C, Yonghui Ma etal. Seven facts and five initiatives for gut microbiome research. Protein & Cell. 2020; 11: 391-400.
2. Zhang YJ, Li S, Gan RY, Zhou T, Xu DP, Li HB. Impacts of gut bacteria on human health and diseases. Int J Mol Sci. 2015;16(4):7493-519.
3. Canny GO, McCormick BA. Bacteria in the Intestine, Helpful Residents or Enemies from Within. Infect and Immun.2008; 76(8): 3360-3373.
4. Guts UK Charity (2018) All you need to know about gut bacteria in health and disease GUTS_Bacteria_In_Health_And_Disease_A5_V1.92.pdf (gutscharity.org.uk) Accessed on June 1, 2023.
5. Jandhyala SM. Role of the normal gut microbiota. World J Gastroenterol. 2015; 21(29): 8787–8803.
6. Shen ZH, Zhu CX, Quan YS, Yang ZY, Wu S, Luo WW, etal. Relationship between intestinal microbiota and ulcerative colitis: Mechanisms and clinical application of probiotics and fecal microbiota transplan-
tation. World J Gastroenterol. 2018;24(1):5-14.
7. Iatcu CO, Steen A, Covasa M. Gut Microbiota and Complications of Type-2 Diabetes. Nutrients. 2021;14(1):166.
8. Zhou Z, Sun B, Yu D. Zhu C. Gut Microbiota: An Important Player in Type 2 Diabetes Mellitus. Front. Cell. Infect. Microbiol.2022; 12:834485.
9. Hu Y-H, Meyer K, Lulla A, Lewis CE, Carnethon MR, Schreiner PJ etal. Gut microbiome and stages of diabetes in middle-aged adults: CARDIA microbiome study. Nutr Metab Lond; 2023.20, 3.
10. de Vos WM, Tilg H, Hul MV, Cani PD. Gut microbiome and health: mechanistic insights. Gut 2022; 71:1020-1032.
11. Gubatan J, Boye TL, Temby M, Sojwal RS, Holman DR, Sinha SR etal. Gut Microbiome in Inflammatory Bowel Disease: Role in Pathogenesis, Dietary Modulation, and Colitis-Associated Colon Cancer.
Microorganisms. 2022; 10(7):1371.
12. Núñez-Sánchez MA, Melgar S, O'Donoghue K, Martínez-Sánchez MA, Fernández-Ruiz VE, Ferrer-Gómez M etal. Crohn's Disease, Host-Microbiota Interactions, and Immunonutrition: Dietary Strategies
Targeting Gut Microbiome as Novel Therapeutic Approaches. Int J Mol Sci. 2022 ;23(15):8361.
13. Zou J, Liu C, Jiang S, Qian D, Duan J. Cross talk between gut microbiota and intestinal mucosal immunity in the development of ulcerative colitis. Infect Immun. 2021; 89: e00014-21.
14. Carabotti M, Scirocco A, Maselli MA, Severi C. The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems. Ann Gastroenterol. 2015;28(2):203-209.
15. Zhang, Y.-J. et al. (2015) Impacts of gut bacteria on human health and diseases, International journal of molecular sciences. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425030/
(Accessed: 06 September 2023)
16. Carpenter, Dr.S. (2012) That gut feeling, Monitor on Psychology. Available at: https://www.apa.org/monitor/2012/09/gut-feeling (Accessed: 06 September 2023).
17. (No date) Home Page: The American Journal of Clinical Nutrition. Available at: https://ajcn.nutrition.org/ (Accessed: 06 September 2023).
18. The role of cortisol in sleep (2022) Natural Medicine Journal. Available at: https://www.naturalmedicinejournal.com/journal/role-cortisol-sleep (Accessed: 06 September 2023).

For any queries, Please contact: National Reference Laboratory (NRL)

Name: ......................................... C 533 TTC Industrial Area MIDC Pawane, Navi


Contact Number: ....................... Mumbai, Mumbai, Maharastra, India - 400 705
www.lupindiagnostics.com

Contact us at: 7030 300 400

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