GANA Total Catalogue 230921
GANA Total Catalogue 230921
GANA Total Catalogue 230921
MEDICAL DEVICES
We also supply the research and development service for
customers. We develop and manufacture any products
in dermal fillers. Mesotherapy and medical cosmetics
field according to customer's need Our MOQ of R&D is
reasonable with competitive price
www.ganarnd.co.kr
Our business division is divided
into three fields
• Medical devices
• Cosmeceuticals and gene therapy products
• R&D and manufacturing
Dr PARK Co.,Ltd
• R&D of gene therapy products
• DNA sequencing (NGS, Sanger sequencing)
• DNA, RNA synthesis
• Bioinformatics
• RNA engineering (si RNA)
• Gene engineering (CRISPR Cas 9. TALENS)
• Peptide sequencing
• Peptide synthesis
• Protein synthesis
• Exosome drug delivery system
• Induced pluripotent stem cell
• Human tissue culture using bio compatible polymer
3D printing technique and IPSC
Address
555, sunil technopia, Dunchon-daero, Jungwon-gu,
Seongnam-si, Gyeonggi-do, South Korea
Office #1108, Factory 1 #103, Factory 2 #905, Factory 3 #902,
Factory 4 # 812, Factory 5 # 909, Factory 6 #904,
Factory 7 #1206, Factory 8 #1208, Factory 9 #913
Zip Code : 13215
TEL : 82-31-732-0242
FAX : 82-2-6455-7512
E-mail : dydgh416@naver.com
Homepage : www.ganarnd.co.kr
Dermal fillers
www.ganarnd.co.kr
Dermal fillers GANA MHS 04
GANA MHS
(Semi permanent)
Filler X
(PCL + HA filler)
Major component
• Made of polycaprolactone 50mg/cc
• Cross linked hyaluronic acid gel 20mg/cc
(HA dermal fillers)
• PCL 5%+ HA 95%
• Average 50um sized polycaprolactone
What is PCL
Polycaprolactone
Polycaprolactone (PCL) is a biodegradable
polyester with a low melting point of around
O
60℃ and a glass transition temperature
O of about -60℃. The most common use of
∩
How it works
Collagen is one of the important support structures found naturally in our skin, helping to
maintain the appropriate tightness, elasticity and suppleness.
Over the course of time, our skin gradually loses its natural collagen, leading to facial laxity and
the formation of wrinkles and folds.
Filler X works differently to traditional dermal fillers, which only address lines, wrinkles and
folds. Thanks to its unique properties, it not only corrects wrinkles and folds but by stimulating
your own collagen to really treat the underlying causes of facial ageing, the effects are gradual
and longer-lasting giving you a natural youthful appearance.
Migration Yes No No
Swelling No Yes No
FILLER X Volume
PCL + HA
PCL
Hyaluronic acid
dermal filers(HA)
Injection Time
3~4 days 2 Months 6~12 Months
Precaution
• All kinds of collagen stimulating dermal filler start to make collagen in 4-6 weeks.
• So be careful before use.
• Once you inject collagen stimulating dermal filler on forehead,
lip There will be lump growing
Recommended dose
• Both Nasolabial fold : 1-2ml
• Both Cheeck : 2-6ml
• Chin : 1-3ml
• Nose : 1-2ml
FILLER X - Patented
Dermal fillers GANA HA 08
GANA HA
(HA filler)
GANA HA is characterized by
1. Non adding of non cross linked HA
2. Highest cross linking ratio
3. Highest HA concentration
4. GANA HA has small particle size so that doctors are easy to make shape
5. Highest viscosity than any other dermal fillers
6. Longest duration
7. Low extruding force
Viscosity.
2-4X 106CPS 1-4X 106CPS 4-7X 106CPS
CPS.
Dermal fillers GANA HA 09
Depth
Recommended dose
1. Nose 1-2ml
2. Nasolabial fold 2-3ml 이마 (A TYPE, BOOSTER TYPE)
3. Forehead 3-5ml
4. Lip each side over 1ml 다크, 애교 (C TYPE, BOOSTER TYPE)
코 (A TYPE, BOOSTER TYPE)
5. Cheek 4-10ml
팔자 (B TYPE, BOOSTER TYPE)
6. Short chin 2-4ml 입술 (B TYPE, BOOSTER TYPE)
7. Sunken eye 1ml 무턱, 뾰족턱 (A TYPE, BOOSTER TYPE)
8. Temporal area depression
each over 2ml
Specification
Test Items Standard Provision Result
24.22.20mg/ml
Hyaluronate Content Qualified
Booster : 10mg/ml
PH 6.5~7.6 Qualified
Recommended dose
HA
Injection Recommended Cross linking Recommended
GANA HA Volume concentration
layer guage ratio use
( mg/cc)
Large volume
A type 1.2ml Sub Q 25 24 10%
augmentation
Moderate
B type 1.2ml Deep dermis 27 22 10%
wrinkle
GANA PH
(PLLA + HA filler)
Major component
PLLA 2% + HA 98%
GANA PH is dermal fillers Average 50um sized PLLA
• Made of Poly-L-lactic acid 20mg/cc 1.2ml syringe × 1EA/box
• Cross linked hyaluronic acid gel 20mg/cc (HA dermal fillers)
What is PLLA
Poly(L-Lactide) is a biodegradable material with good bio-absorbability
and bio-compatibility. After degradation in the body, PLLA products are
excreted by metabolism and thus has no harmful side effects to the human
body. It is for these reasons that PLLA products are currently widely used
in the field of medicine, such as for one-time infusion equipment,medical
surgical suture, drug delivery carriers, tissue engineering scaffolds, bone
anchors, injectable microcapsules, microspheres, implants, elastomer
materials for organ support, etc.
Mechanism
PLLA
(Poly-L-lactic acid) PLLA →
Immune reaction
PLLA degradation
PLLA mechanism
PLLA
collagen
GANA PH
HA fillers PLLA filler GANA PH
Migration Yes No No
Swelling No Yes No
Dissolution with water Not needed Many hours waiting Not needed
GANA PH
Volume
PLLA + HA
PLLA
Hyaluronic acid
dermal filers(HA)
Injection Time
3~4 Days 2 Months 6~12 Months
Dermal fillers GANA PH 12
Recommended dose
• Both Nasolabial fold : 1-2ml
• Both Cheeck : 2-6ml
• Chin : 1-3ml
• Nose : 1-2ml
Precaution
• All kinds of collagen stimulating dermal filler start to make collagen in 4-6 weeks
• So be careful before use
• Once you inject collagen stimulating dermal filler on forehead, lip There will
be lump growing
GANA PN
(PDRN syringe type)
PDRN -polydeoxyribonucleotide
Definition
PDRN is the low molecular weight DNA complex fragments
from salmon or trout sperm.
It play a role in anti inflammatory, cell proliferation and tissue
remodeling.
Protocol
1. 2-3 session is needed
2. Interval one month
3. After second session
The effect can be seen
What Is PDRN?
Polydeoxyribonucleotide is derived from
Preparation
sperm trout through an extraction process.
Apply ice bad and make anesthesia with The compounds are able to stimulate Vascular
lidocaine cream both to reduce pain Endothelial Growth Factors and certain receptors
in the body that trigger the creation of new
artery formation, improves blood flow, and
Precaution reduces inflammation.
Most importantly, PDRN provides the
This product contain nucleotides necessary for cell regeneration.
Cross linked hyaluronic acid(HA) In addition to its use for diabetic foot ulcers,
Not non cross linked hyaluronic acid PDRN has proven effective in treating PAOD,
chronic wounds, hind limb ischemia, osteoarthritis
Once injected to epidermis disease, coronary artery disease, and burn injuries
This can cause nodule and papule
So injection layer will be dermis layer
And use mesotherapy gun needle depth
more than 1.5mm
GANA FILL
(CE approved PLLA filler)
CE and ANVISA approved
What is biodegradable material
The term biodegradable is used to describe materials that decompose
through the actions of bacteria, fungi, and other living organisms-simply
put it has the ability to break down or decompose back into the natural
environment without causing harm Examples of well known biodegradable
materials used in medical industries are PLLA, PLGA, PGA, PDO and PCL
What is PLLA
Poly(L-lactide) is a biodegradable material with good bio-absorbability
and bio-compatibility. After degradation in the body, PLLA products are
excreted by metabolism and thus has no harmful side effects to the human
body. It is for these reasons that PLLA products are currently widely
used in the field of medicine, such as for one-time infusion equipment,
medical surgical suture, drug delivery carriers, tissue engineering
scaffolds, bone anchors, injectable microcapsules, microspheres, implants,
elastomermaterials for organ support, etc.
Mechanism
• PLLA(Poly-L-lactic acid)
• Polymer of Lactic acid
• Lactic acid ➡ CO2 + H2O
collagen
ⓐ ⓑ
Injectable PLLA, the main
component of GANAFill
works in the deep dermis to
create collagen.
ⓒ ⓓ
Dermal fillers GANA FILL 16
GANA FILL
INJECTABLE POLY-L-LACTIC ACID POWDER
Reconstitute with 18ml of sterile water for injections
One vial contains Injectable PLLA 520mg
Made in Korea
GANA FILL-Face
This product is made from a mixture of PLLA powder FDA approved
materials. GANA FILL is more innovative and creative than all existing
products. It induces the formation of collagen which in turn has the effect
of increasing volume of the part where the surgical procedure was done.
The augmentation will continue until the 8th week and will last for 2 years
after the procedure. Main areas of use are temple, cheek, This product
uses the same main ingredients as Sculptra.
Face
First session
· for full face
one vial is max
Second session
· One month later
- Half dose of first session
· Depth of injection
- Subcutaneous layer or periosteum
· Injection technique
- Fan technique using canula
Precaution
1. Do not treatment prohibited area. (lip, nose, forehead)
2. Use distilled water only. (Do not use a saline solution or water.)
3. Don't inject at one spot too much, inject widely and deeply to avoid granuloma formation
4. Patient have to get second treatment. (Check progress)
Nasolabial fold 0.5 vial max One month later half Subcutaneous layer Fan shape injection
Cheek 1 vial max dose of first session or Periosteum usingcannula
GANA CH
(Calcium + HA filler)
Main component
1.2ml syringe × 1EA/box
• Calcium hydroxyapatite 5%
• Cross linked hyaluronic acid 95%
Migration Yes No No
GANA PNS
(PDRN filler)
Major component
1.2ml syringe × 1EA/box
• PDRN (poly deoxyribonucleotide from salmon sperm) 2%
• Cross linked Hyaluronic acid 20mg/cc
How to use
• Unpack box
• Clean the application area
• Attach enclosed needle
• Injection level will be subcutaneous or dermis layer
• If there is bleding, compress area for one minute
What is PDRN?
Polydeoxyribonucleotide is derived from Most importantly, PDRN provides the
sperm trout through an extraction process. nucleotides necessary for cell regeneration.
The compounds are able to stimulate In addition to its use for diabetic foot ulcers,
Vascular Endothelial Growth Factors and PDRN has proven effective in treating
certain receptors in the body that trigger the PAOD, chronic wounds, hind limb ischemia,
creation of new artery formation, improves osteoarthritis disease, coronary artery disease,
blood flow, and reduces inflammation. and burn injuries.
GANA PFS
(Peptide filler)
Main components
1. Cross linked HA 20mg/cc
2. Acetyl hexapeptide 8 (AH8)
3. Palmitoyl tetrapeptide 7
4. Palmitoyl pentapeptide 4
5. PBS
GANA HA body
(Hyaluronic acid dermal fillers)
Main component is
Cross linked hayluronic acid 20mg/cc
Cross linking ratio 10% 50ml prefilled vial
GANA HA is characterized by
1. Non adding of non cross linked HA
2. Highest cross linking ratio
3. Highest HA concentration
4. GANA HA has small particle size so that doctors are easy to make shape
5. Highest viscosity than any other dermal fillers
6. Longest duration
7. Low extruding force
Dermal fillers GANA HA body 22
How to use
1. Remove aluminum cap and rubber stopper
2. Withdraw HA body with 10cc syringe
3. You will have 5 syringes for one vial
4. Make anesthesia at puncture
5. Puncture with 16G or 18G needle
6. Attache 16G or 18G canula to prefilled 10ml syringe
7. Inject GANA HA body to breast or hip
8. Injection are will be subcutaneous fat layer in the hip
9. For breast augmentation. Injection layer will be just above pectoralis major muscle
10. For breast injection. be careful not to damage mammary glands
11. for each breast and hip. minimum dose will be 50ml maximum dose for each
breast will be 200ml
Recommended dose
• For vaginal tightening 50ml
• For partial breast augmentation 50-100ml each
• For full breast augmentation 200ml each
• For partial hip augmentation 50-150ml
• For full hip augmentation 200-400ml each
O
Implants But need Expensive OX Long X
major surgery
Specification
Test Items Standard Provision Result
PH 6.5~7.5 7.3
How to withdraw
• GANA HA body is prefilled vial type
• And has high viscosity
• Need special technique to withdraw
Mix normal saline with body Then you can withdraw Body easily
Dermal fillers GANA HA body 24
Puncture point
Progress
1. For 3-4 days there might be swelling and pain Before and after(200ml both used)
2. Prescribe pain killer, antibiotics and anti
inflammatory for 5days
3. The swelling and pain is normal cause this
products has very high cross linking ration
almost 10%, it absorb water and getting
bigger for a few days It maybe cause Left 150ml VS right before
swelling and pain
4. second session in a month is necessary
The injected dermal filler can migrate
to adjacent area so in second sesssion
practitioner must correct deformed shape
Breast filler
Before and after
Buttock filler
Before and after (300ml used)
GANA booster
(Biorevitalization)
2.5ml × 1EA/box
Preparation
Apply ice bad and make anesthesia with lidocaine cream both to reduce pain
Precaution
This GANA booster (biorevitalization) contain
• Cross linked hyaluronic acid (HA)
• Not non cross linked hyaluronic acid
After injection
Compress treated area with dry gauze
Dermal fillers GANA booster 27
Whitening Yes No
PROTOCOL
1. 2-3 session is needed
2. Interval one month
3. After second session the effect can be seen
Certificate of anaylysis
• Products name : GANA HA Hyrdo
• Production date : 2015-9-15
• Expiratory date : 2016-9-15
• LOT No :
• CAS No. : 9004-61-9
• Molecular formula : (C14H21NO11)n
• Content : 99.9 %
• Grade : Medicine grade.
• Molecular Structure :
Specification
www.ganarnd.co.kr
Cosmetics GANA PHA 29
GANA PHA
(PHA peeling)
PHA peeling
Ingredients
• Polyhydroxy acid 10%
• Alpha arbutin 1% for whitening
Safety of PHA
Even very sensitive skin types can tolerate PHAs, including atopic and rosacea
skin. It is thought that the gentle, nonirritating action of PHAs may be partially
related to a larger molecular composition than that of conventional AHAs.
Larger molecules are believed to penetrate the skin at a slower rate, causing less
irritation. This reduced irritation, coupled with natural antioxidant properties,
gives PHAs a gentle, competitive edge over other anti-aging treatments.
Gluconolactone may be slightly less sensitizing for some skin types, but this isn't
the magic bullet for exfoliation some cosmetics companies have been extolling.
Polyhydroxy acids can also function as antioxidants and may promote some
amount of improvement in skin's surface strength.
Cosmetics GANA PHA 30
GINO FACE
GINO BODY
(Acne/Keratois pilaris)
GANA TOX
(FDA registered spraying peptide)
Argireline
Argireline is made up of peptides, which are chains of amino acids that can
affect how cells in the body work. When Argireline is applied to the skin, it
is absorbed into the body and the cream's chemical composition causes the
facial muscles to contract with less force. Argireline prevents the formation of
expression wrinkles by somehow inhibiting muscle movement.
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction
process. The compounds are able to stimulate Vascular Endothelial Growth
Factors and certain receptors in the body that trigger the creation of new artery
formation, improves blood flow, and reduces inflammation. Most importantly,
PDRN provides the nucleotides necessary for cell regeneration. In addition to
its use for diabetic foot ulcers, PDRN has proven effective in treating PAOD,
chronic wounds, hind limb ischemia, osteoarthritis disease, coronary artery
disease, and burn injuries.
Adenosine
In Anti-Aging Skin Care. Adenosine Triphosphate, also referred to as ATP, is a
type of molecule that is responsible for being the leading source of energy for
the majority of our cellular and muscular functions. It is capable of boosting the
levels of proteins such as Collagen and Elastin in the body.
Palmitoyl tetrapeptide-7
Palmitoyl tetrapeptide-7 is a type of synthetic peptide compound which combines
several chains of amino acids to reduce skin inflammation and the accompanying
skin damage. This peptide compound is also believed to stimulate the regeneration
of collagen fibers in the dermis by acting as sort of cellular messenger.
Palmitoyl tetrapeptide-7(Pal-GQPR) is. (It was also formerly known and marketed
as palmitoyl tetrapeptide-3.)
Palmitoyl tetrapeptide-7 consists of a short chain of four amino acids (a.k.a. GQPR
peptide or glycine-glutamine-proline-arginine) connected to palmitic acid.
Palmitic acid is a fatty acid added to improve the peptide's oil solubility and thus
skin penetration.
Palmitoyl tetrapeptide-7 is believed to work by reducing the production of
interleukin-6 (IL-6) by the the key skin cells, keratinocytes and fibroblasts.
IL-6 is a molecule that promotes inflammation, which, in turn, leads to faster
degradation of the skin matrix and thus contributes to the development of
wrinkles and loss of skin firmness and elasticity.
By reducing the levels of IL-6 and possibly other inflammation mediators,
palmitoyl tetrapeptide-7 is thought to slow down the degradation of the skin
matrix and may also stimulate its replenishment.
Palmitoyl Pentapeptide-4
Pentapeptide-4 activates certain genes involved in the process of extracellular
matrix renewal and cell proliferation.
Cosmetics GANA TOX 35
Its 16-carbon aliphatic chain is for improving the penetration of the molecule
through the lipid structures of the skin.
Stimulates collagen I, III and VI fibronectin, elastin, glucosamnoglycans production.
Palmitoyl Pentapeptide is a compound that is derived from a five-part chain of
amino acids known as pro-collagen I pentapeptide.
By itself, this amino chain has been shown to increase the production of
collagen in laboratory cultures.
Palmitoyl pentapeptide is a synthetic derivative of this five-part amino acid
chain, and it is normally marketed under the brand name Matrixyl, which is
simply a combination of palmitic acids and amino-acid chains.
Functionally, Palmitoyl Pentapeptide promotes the production of two compounds:
collagen and hyaluronic acid. Combined, these compounds help the skin recover and
heal from wounds and penetrative damage by generating new specialized skin
cells that bind the damaged tissue together.
How to use
Topical apply
1. Half vial is for full face
One vial is for full face and neck
2. Apply GANA TOX before go to bed
3. Interval 2-3 times a week
4. 5-6 session is needed
5. You will see the effect after 5th session
Open GANA TOX vial Pour GANA TOX in the cup of air spray gun
Turn on the air spray gun Push the button of the air spray gun
Cosmetics GANA PNV 36
GANA PNV
(PDRN vial type)
Major component
• PDRN (poly deoxyribonucleotide from salmon sperm) 0.5%
• Glutathione 2mg/cc
• Cross linked Hyaluronic acid 5mg/cc
PDRN
• Help all kinds of wound healing,
• Regeneration of cell and tissue
Glutathione
• Whitening
PDRN (polydeoxyribonucleotide)
Definition
PDRN is the low molecular weight DNA complex fragments from
salmon or trout sperm. It play a role in anti inflammatory, cell
proliferation and tissue remodeling.
Cosmetics GANA PNV 37
Application
• Face rejuvenation
• Acne scar
• Wrinkle removal
• Whitening
• Preventing sagging
• Improving elasticity, turgidity and tonicity of skin
• Repairing damaged dermal cells
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction process.
The compounds are able to stimulate Vascular Endothelial Growth Factors and certain
receptors in the body that trigger the creation of new artery formation, improves blood
flow, and reduces inflammation. Most importantly, PDRN provides the nucleotides
necessary for cell regeneration.
In addition to its use for diabetic foot ulcers, PDRN has proven effective in treating
PAOD, chronic wounds, hind limb ischemia, osteoarthritis disease, coronary artery
disease, and burn injuries
2. Derma roller
• Use 0.2mm to 0.5mm needle length derma roller
• Interval 1wk
• 3 sessions
Cosmetics GANA PNV 38
Preparation
Post procedure care
Apply ice bad and make anesthesia with
lidocaine cream both to reduce pain 1. Apply mask pack for skin suppression
2. Avoid direct sun light
3. In case of mild pain, patients can take
NSAID
Precaution
This product contain
Cross linked hyaluronic acid (HA)
Not non cross linked hyaluronic acid
Contraindication
1. Any kinds of active skin disease
2. Any kinds of general illness
3. Hypersensitive to this products
4. Bleeding disorder
5. Pregnancy, breast feeding
Precaution
• This products contain cross linked
hyaluronic acid
• Be careful not to penetrate artery
• Cross linked HA can cause arterial occlusion Before and after
Side effect
• Bruising
• Hematoma
• Atrophy & Skin hypertrophy
• Erythema
• Urticaria
Cosmetics REGEN PEEL 39
REGEN PEEL
(TCA peeling)
Ingredient
REGEN PEEL
30% Trichloroacetic acid
purified water
Warning
• This is a strongest TCA peeling
• The beginner never use it
• This is only for dermatologists
Explanation
This is a professional grade TCA peel with an unbuffered pH of 1.3. TCA is the
peel that all other peels are compared to! It has been around for decades, is
easy to use, and very predictable. Most dermotologists prefer to use TCA over
other acids due to its effectiveness and dependability. If you are looking for
long-lasting, dramatic changes in your skin, TCA is the correct choice for you.
• Acne
• Skin Tone Irregularities
• Texture Problems
• Age Spots
• Fine Wrinkles
• Scarring and Acne Scars
Cosmetics REGEN PEEL 40
Step 1 ❶ ❷
Test the TCA on a small patch of skin before applying
it to your face. Wait 24 hours to see if you tolerate
the peel.
Step 2
Apply a thin layer of TCA to your skin with a facial
brush. Avoid the eye and lip areas.
Step 3 ❸ ❹
Neutralize regen peel with neutralizer.
In a minute Time is important.
Step 4
Apply a generous amount of post-peel neutralizer
to your skin. Cover every area on which you applied
TCA to ensure that you neutralize the chemical.
Step 5 Things You'll Need
Wash your face with cleanser and apply antibiotic - Skin cleanser
ointment to your skin for the first 48 hours after - Latex gloves
your peel. - Facial brush
- Kitchen timer
Step 6 - Post-peel neutralizer
Protect your skin with a sunblock with SPF 30 or - Antibiotic ointment
higher for a week after your peel. - SPF 30 sunblock
Cosmetics GANA Cocktail 41
GANA Cocktail
(Whitening)
Ingredients
• Glutathione : 4mll × 5vials
• Vitamin C (ascorbic acid) : 4ml × 5Vials
Attention
Never mix Glutathione and Vitamin C
Vitamin C Revitalizing & Antioxidant Solution is used mainly to treat and prevent
photoageing, uneven complexions and for helping the skin to fight wrinkles.
Ascorbic acid is one of the main non-enzymatic, water-soluble antioxidant.
Vitamin C is required for the synthesis of collagen, an important structural
component of blood vessels, tendons, ligaments and bones.
In addition, vitamin C is required for the synthesis of carnitine, a small molecule that
is essential for the transport of fat to ce-llular organelles called mitochondria,
for conversion to energy.
Caution
Glutathione and Vitamin C can not be mixed for use
How to use
• Apply biweekly
• Glutathione - 1st 3rd 5th week
• Ascorbic acid - 2nd 4th 6th week
Cosmetics GANA SCALP 43
GANA SCALP
(Hair care)
PDRN × 5 vials
GHK_CU × 5 vials
3ml × 10EA
Caution - use for hair growth
• Do no use for other use
• Do not use on the face and neck
Ingredients
• PDRN (poly deoxyribonucleotide)
• Copper peptide
Copper peptides are naturally occurring small protein fragments that have
high affinity to copper ions. In human plasma, the level of GHK-Cu is about
200 µg/ml at age 20. By the age of 60, the level drops to 80 µg/ml.
In humans, tripeptide GHK-Cu can promote activation of wound healing,
attraction of immune cells, antioxidant and anti-inflammatory effects,
stimulation of collagen and glycosaminoglycan synthesis in skin fibroblasts
and promotion of blood vessels growth.
Hair growth
Copper peptide GHK-Cu and its analogues
were found to stimulate hair growth. In some
circumstances, the efficiency of synthetic
analog of GHK-Cu was similar to that of 5%
minoxidil.
A commercial product GraftCyte was clinically
proven to improve hair transplantation
outcome.
Shown to promote collagen production,
using copper peptides topically on the scalp
will help strengthen already existing hair,
while stimulating growth in areas that are
lacking thickness.
Cosmetics GANA PNV plus 45
GANA PNV +
(high PDRN)
Major component
• PDRN (poly deoxyribonucleotide from salmon sperm) 2%
• Glutathione 2mg/cc
• Cross linked Hyaluronic acid 10mg/cc
• GANA PNV plus is mesotherapysolution, prefilled in vials
PDRN
• Help all kinds of wound healing,
• Regeneration of cell and tissue
Glutathione
• Whitening
PDRN( polydeoxyribonucleotide)
Definition
PDRN is the low molecular weight DNA complex fragments
from salmon or trout sperm. It play a role in anti inflammatory,
cell proliferation and tissue remodeling.
Cosmetics GANA PNV plus 46
Application
• Face rejuvenation
• Acne scar
• Wrinkle removal
• Whitening
• Preventing sagging
• Improving elasticity, turgidity and tonicity of skin
• Repairing damaged dermal cells
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction process.
The compounds are able to stimulate Vascular Endothelial Growth Factors and certain
receptors in the body that trigger the creation of new artery formation, improves blood
flow, and reduces inflammation. Most importantly, PDRN provides the nucleotides
necessary for cell regeneration.
In addition to its use for diabetic foot ulcers, PDRN has proven effective in treating
PAOD, chronic wounds, hind limb ischemia, osteoarthritis disease, coronary artery
disease, and burn injuries.
2. Derma roller
• Use 0.2mm to 0.5mm needle length derma roller
• Interval 1wk
• 3 sessions
• One vial for each session
• Dose : cheek 5 to 15ml
forehead 5 to 10ml
second session in a month needed
Cosmetics GANA PNV plus 47
Preparation
Apply ice bad and make anesthesia with
lidocaine cream both to reduce pain
Precaution
This product contain Side effect
Cross linked hyaluronic acid (HA) • Bruising
Not non cross linked hyaluronic acid • Hematoma
• Atrophy & Skin hypertrophy
Once injected to epidermis • Erythema
• Urticaria
This can cause nodule and papule
So injection layer will be dermis layer
And use mesotherapy gun. needle depth
more than 1.5mm
After injection
Compress treated area with dry gauze
Use Mesogun.
MTS or enclosed 30G needles
Precaution
• This products contain cross linked
hyaluronic acid
• Be careful not to penetrate artery
• Cross linked HA can cause arterial occlusion
Cosmetics GANA PNV plus 48
CASE 1
Used GANA PNV plus
(=same components as GANA PN)
Skin tone and skin irregularity were improved
# Procedured by Dr Vita Mastrolonardo
Aesthetic and Anesthesologist Dr Importaciones CruzAng
CASE 2
Used GANA PNV plus
(=same components as GANA PN)
Sagging jaw line
Skin irregularity on cheek
much improved
# Procedured by Dr. Oxmerari Chirivella
Plastic Surgeon of the Venezuelan Society of Plastic Surgeon
(SVCPREM)
Importaciones CruzAng Venezuela
GANA EYE
(Eye bag removal)
Main components
• Carnitine : 2%
• Acetyl tetrapeptide-5 : 50ppm
• Phosphate buffer solution-q.s
Packaging
• 2ml/5ml prefilled vials × 5EA in a box
One box GANA EYE can be used for more than 20 sessions
Cosmetics GANA DM 50
GANA DM
(PLLA meso)
What is PLLA
• PLLA is powerful collagen stimulator in human body
• PLLA induce collagen syntheis in 6weeks
• Once collagen made it last more than 5years
• Newly formed collgen make volume for depressed area
• And induce lifting by tightening of face
• So newly formed PLLA recover depressed area, like acne scar.
stretch marks
1. ThePLLA in Gana DM
- The size of PLLA particles in the conventional products is average 30 to
50um size.
Conventional GANA DM
HA concentration (mg/cc) 10 10
Application
• Stretch mark (striae)
• Acne scar
• Big pore
• Face rejuvenation
• Face lifting by collagen synthesis
• Neck wrinkle
• Hand wrinkle
Stretch mark
Before procedure
Procedure by Russian distributor.
BIOMED co ltd
Stretch mark procedure
After procedure
Only left belly was done
One session
After 6weeks
Cosmetics GANA DM 52
Aging
PLLA 1. Water loss
2. Collagen loss
collagen 3. Elasticity loss
GANA DM set
VORTEX MIXER
PLLA powder for mesotherapy
• Main component is poly L lactic acid
PLLA is collagen stimulator, induce collagenesis
by activating fibroblast
• GANA DM set is autoclaved cross linked
hyaluronic acid How to use for stretch marks,
acne scar and neck wrinkle
The merits of GANA DM set. Prefilled vial
• Prepare DM set solution
• Interval one month
Major component • Total 2-3 sessions will be needed
• Cross linked hyaluronic acid gel
(longer duration and better efficacy)
• Autoclave sterilized (better safety)
Cosmetics GANA PF 53
GANA PF
(Expression wrinkle removal)
GANA PF is made to
remove wrinkle effectively Packing unit : 2ml × 5 vials
It contain cross linked HA and
peptides good for wrinkle removal
Ingredients
• Cross linked hyaluronic acid 15mg/cc What is cross linked hyaluronic acid
• Acetyl hexapeptide 50ppm and acetyl hexapeptide
• PBS-qs
1. Use only for fine shallow wrinkle Cross linked HA is not normal HA of
ex) forehead, crow feet, under eye fine wrinkle cosmetics. This is mani components of
dermal fillers.
2. Do not use this product for deep wrinkle Cross HA is linked by BDDE (cross linker) to
like nasolabial fold and lips stay in human skin more than 6 months up
3. Do not use this products for augmenation to 18 months.
Restore depressed soft tissue so that to
4. Cause of acetyl hexa peptide elevate sunken wrinkle and store water in
The some person might feel paralyzed dermis.
facial expression
It is normal expectation Acetyl hexapeptide
Reassure patients
Is made up of peptides, which are chains of
amino acids that can affect how cells in the
body work.
When Acetyl hexapeptide is applied to the
skin, it is absorbed into the body and the
cream's chemical composition causes the
facial muscles to contract with less force.
Acetyl hexapeptide prevents the formation
of expression wrinkles by somehow inhibiting
muscle movement.
Cosmetics GANA GYNO 54
GANA GYNO
(Vaginal whitening with
vegetable estrogen)
Ingredients
• Glutathione
• Isoflavone pharmaceutical grade
• Xanthan gum
• Glycerine
• Lactic acid
What is glutathione
Glutathione is the body's most powerful antioxidant, unknown by most.
It is popular when used as a way to help whiten skin though. Glutathione
skin whitening is growing in popularity, helping people achieve the skin
pigmentation they desire with no harmful side effects when taken in proper
dosages.
What is Isoflavone
1) SoyIsoflavones is a standardized natural extract containing soy isoflavone
aglycones, genistein and daidzein. It has anti-aging and antioxidants benefits.
Soy isoflavonesexhibit estrogen-like properties that may help maintain skin
texture and integrity, prevent wrinkles and stimulate hyaluronic acid.
The antioxidant effects of soy isoflavones are also useful in protecting the
skin against photo damage thereby preventing aging, as well as reducing
the appearance of current age spots. The estrogen-like qualities of this
product can also be used in hair care products to enhance hair regrowth.
GANA TM
(FDA registered mask pack)
Effects
Very effective for
1. Skin rejuvenation by PDRN (salmon sperm DNA)
2. Mild and non irritable peeling by PHA
3. Wrinkle removal and face lifting by acetyl hexapeptide-8
4. Immediate hydration and skin defect recovering
by Cross linked hyaluronic acid
Main ingredients
• PDRN (poly deoxy ribo nucleotide)
• PHA (poly hydroxy acid)
• Acetyl hexapeptide-8
(similar function to botulinum toxin)
• Cross linked hyaluronic acid
(main components of dermal fillers)
Detail ingredients
• Lactobionic acid(=PHA)
• Acetyl hexapeptide-8(=arigirelline)
3 mask packs/box
• Alpha arbutin(goof for whitening)
• Adenosin
• Palmitoyl tetrapeptide7
• Palmitoyl pentapeptide 4
• 1.2 hexandiol
• Bio cellulose
• Cross linked hyaluronic acid
Cosmetics GANA TM 56
The significant difference between them and • PHAs plus hydroquinone showed excellent
AHAs is that gluconolactone and lactobionic improvement in antiaging and skin
acid have larger molecular structures, which lightening parameters.
limits their ability to penetrate the skin, resulting • Finally, PHA-containing products were
in less potential for sensitizing side-effects. shown to be compatible with African
Supposedly, this reduced absorption into the American, Caucasian, and Hispanic/Asian
skin and provided significant improvements
skin does not hamper their effectiveness. in photoaging in these populations.
Does that mean gluconolactone and lactobionic
acid are better for your skin than AHAs in the
form of glycolic acid or lactic acid?
According to an Internet-published class PHA face peel is indicated for :
lecture by Dr. Mark G. Rubin, a board-certified • Acne-prone skin
dermatologist and assistant clinical professor • Comedones
of dermatology at the University of California, • Enlarged pores
San Diego, research on gluconolactone • Hyperpigmentation and uneven skin tone
demonstrated only a "6% decrease in dermal • Skin aging prevention
penetration" in comparison to glycolic acid, • Early signs of photoaging such as skin
which "isn't a dramatic improvement." dryness
Gluconolactone may be slightly less sensitizing • Loss of elasticity and fine lines
for some skin types, but this isn't the magic • Hyperkeratosis
bullet for exfoliation some cosmetics (Rosacea, seborrheic dermatitis)
companies have been extolling. • Actinic dermatitis
Polyhydroxy acids can also function as • Correction and prevention of natural aging
antioxidants and may promote some amount signs such as withering and first wrinkles
of improvement in skin's surface strength pigmentation
GANA MASK
(Facial burn mask)
Development objective
GANA MASK is developed for curing any kinds of burn damage of face
including laser therapy and chemical peeling
What is difference,
• As soon as applied to patient GANA MASK can keep
moisturizing from evaporation
• Prevent infection
• Mechanical-chemical protection
• Reduce pain
- PLLA Powder in GANA MASK stimulate the collgen
synthesis of soft tissue defect
• High concentration Cross linked hyaluronic acid gel absorb
watery content from wound and fill defected skin area.
• PDRN in GANA MASK help to heal wounded skin
GANA MASK
Introduction of contents
Epithelium and Soft tissues regeneration One of the chief components of the extracellular
matrix, hyaluronan contributes significantly
• The function of GANA MASK powder
to cell proliferation and migration, and may
(PLLA, PDRN)
also be involved in the progression of some
• Improve soft tissue regeneration malignant tumors.
• Improve epidermis regeneration
• Absorb exudate The average 70 kg(154 lb) person has roughly
• In case of major burns is accompanied by 15 grams of hyaluronan in the body, one-
soft tissue loss and epithelium damage. third of which is turned over (degraded and
The frozen dried powder has functions for synthesized) every day.
epithelium and soft tissue regeneration. Hyaluronic acid is also a component of the
It can be applied on burn injury before group A streptococcal extracellular capsule,and
applying the sheet is soaked gel up. is believed to play a role in virulence.
Cosmetics GANA MASK 61
Mechanism
PLLA
(Poly-L-lactic acid) PLLA →
Immune reaction
PLLA degradation
PLLA
collagen
How to use
1. Clean face
2. Apply GANA MASK for 20min
3. Remove pack
4. Do not wash face after using GANA MASK
Cosmetics GANA TC plus 62
GANA TC plus
(PDRN, PHA.AH8 ointments)
Effects
Very effective for
1. Skin rejuvenation by PDRN (salmon sperm DNA)
2. Mild and non irritable peeling by PHA
3. Wrinkle removal and face lifting by acetyl hexapeptide-8
4. Immediate hydration and skin defect recovering
by Cross linked hyaluronic acid
Tube type - 45gram
Main ingredients
• PDRN (poly deoxy ribo nucleotide) 2%
• Lactobionic acid 2%
• Acetyl hexapeptide-8 (similar function to botulinum toxin) 50ppm
• Cross linked hyaluronic acid (main components of dermal fillers) 1%
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction
process.
The compounds are able to stimulate Vascular Endothelial Growth Factors
and certain receptors in the body that trigger the creation of new artery
formation, improves blood flow, and reduces inflammation.
Most importantly, PDRN provides the nucleotides necessary for cell regeneration.
In addition to its use for diabetic foot ulcers, PDRN has proven effective in
treating PAOD, chronic wounds, hind limb ischemia, osteoarthritis disease,
coronary artery disease, and burn injuries
Supposedly, this reduced absorption into the skin does not hamper their
effectiveness.
Does that mean gluconolactone and lactobionic acid are better for your skin
than AHAs in the form of glycolic acid or lactic acid?
According to an Internet-published class lecture by Dr. Mark G. Rubin, a
board-certified dermatologist and assistant clinical professor of dermatology
at the University of California, San Diego, research on gluconolactone
demonstrated only a "6% decrease in dermal penetration" in comparison to
glycolic acid, which "isn't a dramatic improvement."
Gluconolactone may be slightly less sensitizing for some skin types, but this
isn't the magic bullet for exfoliation some cosmetics companies have been
extolling.
Polyhydroxy acids can also function as antioxidants and may promote some
amount of improvement in skin's surface strength
Cosmetics GANA TC 64
GANA TC
(PDRN, PHA.AH8 ointments)
Effects
Very effective for
1. Skin rejuvenation by PDRN (salmon sperm DNA)
2. Mild and non irritable peeling by PHA
3. Wrinkle removal and face lifting by acetyl hexapeptide-8
4. Immediate hydration and skin defect recovering
by Cross linked hyaluronic acid
Tube type - 45gram
Main ingredients
• PDRN (poly deoxy ribo nucleotide) 0.5%
• Lactobionic acid 0.5%
• Acetyl hexapeptide-8 (similar function to botulinum toxin) 25ppm
• Cross linked hyaluronic acid (main components of dermal fillers) 1%
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction
process.
The compounds are able to stimulate Vascular Endothelial Growth Factors
and certain receptors in the body that trigger the creation of new artery
formation, improves blood flow, and reduces inflammation.
Most importantly, PDRN provides the nucleotides necessary for cell regeneration.
In addition to its use for diabetic foot ulcers, PDRN has proven effective in
treating PAOD, chronic wounds, hind limb ischemia, osteoarthritis disease,
coronary artery disease, and burn injuries
Supposedly, this reduced absorption into the skin does not hamper their
effectiveness.
Does that mean gluconolactone and lactobionic acid are better for your skin
than AHAs in the form of glycolic acid or lactic acid?
According to an Internet-published class lecture by Dr. Mark G. Rubin, a
board-certified dermatologist and assistant clinical professor of dermatology
at the University of California, San Diego, research on gluconolactone
demonstrated only a "6% decrease in dermal penetration" in comparison to
glycolic acid, which "isn't a dramatic improvement."
Gluconolactone may be slightly less sensitizing for some skin types, but this
isn't the magic bullet for exfoliation some cosmetics companies have been
extolling.
Polyhydroxy acids can also function as antioxidants and may promote some
amount of improvement in skin's surface strength
Cosmetics GANA BB 66
GANA BB
(BB with PDRN ointments)
GANA BB is
BB cream containing PDRN
And made for Caucasian
Color and flavor are customized to european
PDRN is good for skin regeneration
SPF 35
What Is PDRN?
Polydeoxyribonucleotide is derived from sperm trout through an extraction
process.
The compounds are able to stimulate Vascular Endothelial Growth Factors
and certain receptors in the body that trigger the creation of new artery
formation, improves blood flow, and reduces inflammation. Most importantly,
PDRN provides the nucleotides necessary for cell regeneration.
In addition to its use for diabetic foot ulcers, PDRN has proven effective in
treating PAOD, chronic wounds, hind limb ischemia, osteoarthritis disease,
coronary artery disease, and burn injuries
GANA KA
(Kojic acid ointment)
GANA V line
(Face contour improval)
GANA V line
Face contour improvement solution
Ingredients
• Phosphatidylcholine (PPC)
• Deoxycholic acid (DA)
• Acetylhexapeptide-8
• Glutathione
• Benzyl alcohol
Main effect
• Dissolve facial fat by PPC and DA
• Wrinkle removal and face lifting by Acetyl hexapeptide-8
• Whitening by glutathione
Dr park's TELO
(Telomere)
Ingredients
Package unit : 3ml × 5vials/box
1. Synthesized Telomere. 50ng/ml
Repeted TTAGGG sequence. 60 base pair
2. PDRN (polydeoxyribonucleotide) 2000ppm
3. Cross linked hyaluronic acid 10mg/ml
4. Glutatione 1%
Oligonucleotide synthesizer
Oligonucleotide synthesis is the chemical synthesis of relatively short fragments
of nucleic acids with defined chemical structure (sequence).
The technique is extremely useful in current laboratory practice because it
provides a rapid and inexpensive access to custom-made oligonucleotides of
the desired sequence. Whereas enzymes synthesize DNA and RNA only in a 5'
to 3' direction, chemical oligonucleotide synthesis does not have this limitation,
although it is, most often, carried out in the opposite, 3' to 5' direction. Currently,
the process is implemented as solid-phase synthesis using phosphoramidite
method and phosphoramidite building blocks derived from protected
2'-deoxynucleosides (dA, dC, dG, and T), ribonucleosides (A, C, G, and U), or
chemically modified nucleosides, e.g. LNA or BNA.
Cosmetics GANA DA 70
GANA DA
(Lipolysis)
Lipolysis solution for double chin and body
Do not use it for face
Ingredients
Deoxycholic acid 10mg/cc
Q.S-Phosphate buffer solution
Purpose
Packaging : 5ml × 10 vials
Emulsifying subcutaneous fat in double chin
Deoxycholates and bile acid derivatives in general are actively being studied
as structures for incorporation in nanotechnology. They also have found
application in microlithography as photoresistant components.
Deoxycholic acid
Cosmetics GANA booster-V 71
GANA booster-V
(GANA booster in vial)
Biorevitalization
Ingredients
• Cross linked hyaluronic acid 10mg/CC
• Glutathione 1mg/cc
Packaging unit
• 3ml/5ml vials × 2EA/box
Cosmetics GANA HA-V 72
GANA HA-V
(GANA HA-B type in vial)
Ingredients
• Cross linked hyaluronic acid
• Concentration : 22mg/cc
Packaging unit
• 3ml/5ml vial × 2EA/box
Cosmetics GANA peptides (APDN) 73
GANA peptides
(APDN)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
What is SYN-AKE
• SYN-AKE is synthesized viper venom tripeptide
• Effect : Anti-wrinkle effect in a month
• Antagonist of acetylcholine receptor
• Relax muscle
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (Carnosine) 74
GANA peptides
(Carnosine)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
what is carnoisine?
L-Carnosine CAS : 305-84-0
beta-alanyl-L-histidine
Carnosine can increase the Hayflick limit in human fibroblasts, as well as
appearing to reduce the telomere shortening rate.
It is also considered as a geroprotector.
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (AH8) 75
GANA peptides
(AH8)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collagen formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
What is AH8?
Acetyl hexapeptide is made up of peptides, which are chains of amino acids
that can affect how cells in the body work. When Acetyl hexapeptide is
applied to the skin, it is absorbed into the body and the cream's chemical
composition causes the facial muscles to contract with less force. Acetyl
hexapeptide prevents the formation of expression wrinkles by somehow
inhibiting muscle movement.
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (PP3) 76
GANA peptides
(PP3)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collagen formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
Sequence
• H-Gly-Pro-Arg-Pro-Ala-OH
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides( PT1) 77
GANA peptides
(PT1)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
Palmitoyl Tripeptide-1
palmitoyl tripeptide-1. Also known as pal-GHK and palmitoyl oligopeptide,
palmitoyl tripeptide-1 is a synthetic fatty acid-linked peptide that can help
repair visible skin damage and strengthen skin's underlying supportive elements.
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (MP17) 78
GANA peptides
(MP17)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collagen formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
Peptide sequence
N2-(1-Oxotetradecyl)-L-lysyl-L-leucyl-L-alanyl-L-lysyl-L-lysinamide
How to use
1. Clean face with alcohol
2. Apply peptide solution
- Half vial for one session with eye brush be careful
not to peptide get in to eyes
3. Interval 2 weeks
4. Total 3-4 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (AGH1) 79
GANA peptides
(AGH1)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (AT5) 80
GANA peptides
(AT5)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for both eyebag with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA peptides (NP1) 81
GANA peptides
(NP1)
What is peptide?
The peptides are chain of amino acids
3ml × 2vilals/box
The each peptides has different amino acids sequence
Each peptides has different function
For example
• Whitening
• Collage formation
• Wrinkle removal
• Muscle relaxation like botulinum toxin
Description
Nonapeptide-1 can prevent melanin synthesis and unwanted pigmentation by
preventing activation of the tyrosinase, thus allowing for a better control over skin tone.
Functions
Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various
kinds of whitening or spot corrective products.
How to use
1. Clean face with alcohol
2. Apply peptide solution
- one vial for whole face with 0.2 mm dermaroller or dermastamp to
facilitate peptide absorption
3. Interval 2 weeks
4. Total 2-3 session will be needed
TIP
Each peptides has different function
So each peptides can be mixed with other peptides
To make peptides cocktail or other skin booster
For better effect
Cosmetics GANA AM 82
GANA AM
Main component
Astragalus Membranaceus Root Extract 100ppm
3ml × 2vilals/box
Telomere are the caps at the end of each strand of DNA that protect our
chromosomes, like the plastic tips at the end of shoelaces.
Without the coating, shoelaces become frayed until they can no longer do
their job, just as without telomeres, DNA strands become damaged and our
cells can't do their job.
www.ganarnd.co.kr
Clinic care GANA LIFT 84
GANA LIFT
(Cone type lifting)
Currently not in production
What is Dr.S?
Dr.S is the advanced concept of the Lift thread which lifts the wrinkled face
from aging and the body which lost its elasticity.
Dr.S improved demerits of existing lift thread and maximized the effect and
the maintenance power and the efficiency.
Thread
USP No.1 PP (Polypropylene)
CONE
PLLA (Poly-L-Lactic-Acid) Screw Anchor type 4mm Cone, Biodegradation
What is PLLA
Poly(L-lactide) is a biodegradable material with good bio-absorbability and bio-
compatibility. After degradation in the body, PLLA products are excreted by
metabolism and thus has no harmful side effects to the human body. It is for
these reasons that PLLA products are currently widely used in the field of
medicine, such as for one-time infusion equipment, medical surgical suture,
drug delivery carriers, tissue engineering scaffolds, bone anchors, injectable
microcapsules, microspheres, implants, elastomermaterials for organ support, etc.
2 Types of Dr.S
Maintenance : 3 year
Efficiency : High tensile lifting effect and reliable traction
Cone : Poly-L-Lactic-acid
Thread USP No.1 : Strong Lift effect
Screw Anchor type cone : 4mm Cone, Biodegradation
Ring : Ultrasonic welding method
The Operation
Dr.S Advantage
Strong Effect face and body : PP thread, Big size Screw Anchor type cone(4mm)
Dr. S Efficiency : High tensile lifting effect and reliable traction.
Biodegradable material safe cones in the human body.
Maintenance : 3 years
Not need to Incisionalface lifting methods
The lifting effect can be seen immediately after the procedure.
GANA PDO
(Cog threads)
Bidirectional
GANA PDO two needles 100 mm 400 mm 1-0 19G
cog
GANA PDO
19G-100mm
W type
one pack include 20 threads
Clinic care GANA PDO 87
W type Bidirectional
GANA PDO 19G-100mm 100 mm 150 mm 1-0 19 guage 6D
cannula cog
W type Bidirectional
GANA PDO 18G-100mm 100 mm 150 mm 1 18 G 6D
cannula cog
Directional
GANA PDO two needles 100 mm 400 mm 1-0 19G 6D
cog
GANA PDO
Double arm
Two needles 400mm
Two threads in one box
GANA PATCH
KFDA approved
(Wound dressing)
Bacterial cellulose
GANA PATCH
Wound covering materials
Development objective
It is impossible to cure patients who has widespread damage skin so far.
What is difference,
• As soon as applied to patient GANA PATCH can keep moisturizing from
evaporation
• Prevent infection
• Mechanical-chemical protection
• Absorb exudate
• Reduce pain
• Components in GANA PATCH stimulate the collgen synthesis of soft tissue
defect so that there will be no more exudate
• High concentration Cross linked hyaluronic acid gel absorb watery content
from wound.
Stuff soft tissue defect immediately and keep moisturizing from evaporation.
• Do not need to change dressing every day.
Change GANA PATCH every week.
Clinic care GANA PATCH 89
Progress
Bio cellulose itself does not cause any immune side effect and any other
response in the body. The epithelial cell migrates to GANA PATCH and then
GANA PATCH may be positioned under the epidermis.
Bacterial cellulose
Bacterial cellulose is an organic compound with the formula (C6H10O5)n) produced by
certain types of bacteria. While cellulose is a basic structural material of most plants, it
is also produced by bacteria, principally of the genera Acetobacter, Sarcina ventriculi and
Agrobacterium. Bacterial, or microbial, cellulose has different properties from plant cellulose
and is characterized by high purity, strength, moldability and increased water holding ability.
[1] In natural habitats, the majority of bacteria synthesize extracellular polysaccharides, such
as cellulose, which form protective envelopes around the cells. While bacterial cellulose is
produced in nature, many methods are currently being investigated to enhance cellulose
growth from cultures in laboratories as a large-scale process. By controlling synthesis
methods, the resulting microbial cellulose can be tailored to have specific desirable
properties. For example, attention has been given to the bacteria Acetobacter xylinum
due to its cellulose's unique mechanical properties and applications to biotechnology,
microbiology, and materials science. Historically, bacterial cellulose has been limited to the
manufacture of Nata de coco, a South-East Asian food product.[2] With advances in the
ability to synthesize and characterize bacterial cellulose, the material is being used for a
wide variety of commercial applications including textiles, cosmetics, and food products,
as well as medical applications. Many patents have been issued in microbial cellulose
applications and several active areas of research are attempting to better characterize
microbial cellulose and utilize it in new areas.[1]
Clinic care GANA PATCH 90
SEM findings of
Bacterial cellulose
Bacterial cellulose aperture is so small
Any kinds of cells and bacteria can not pass through
only water can pass through
And surface area of bacterial cellulose is so wide
Biocellulose can hold a lot of water inside
In conclusion
Biocelluose can protect any kinds of infection
Absorb exudate from wound and evaporate water outward
••Hyaluronic acid (HA;conjugate base hyaluronate), also called hyaluronan, is an anionic, nonsulfatedglycosaminogly
can distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans
in that it is nonsulfated, forms in the plasma membrane instead of the Golgi apparatus, and can be very large, with its
molecular weight often reaching the millions.[2] One of the chief components of the extracellular matrix, hyaluronan
contributes significantly to cell proliferation and migration, and may also be involved in the progression of some
malignant tumors.[3]
•The average 70kg (154lb) person has roughly 15grams of hyaluronan in the body, one-third of which is turned
over (degraded and synthesized) every day.[4] Hyaluronic acid is also a component of the group A streptococcal
extracellular capsule,[5] and is believed to play a role in virulence.[6][7]
How to use
1. Sterilize wound
2. Take out GANA PATCH sheet out of bottle. Use sterile technique
3. Cover GANA PATCH sheet on the wound
4. Cover GANA PATCH sheet with sterile gauze
5. Change GANA PATCH every week
So you do not have to clean the wound every day
just check wound whether there is infection
❶ ❷
❸ ❹