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    Handbook of Cancer Chemotherapy: Sixth Edition

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    Rajesh R
    This document is the sixth edition of the Handbook of Cancer Chemotherapy, which provides an overview of the basic principles, agents used, and treatment approaches for various types of cancer. It is edited by Dr. Roland T. Skeel and contains 31 chapters contributed by experts in oncology. The chapters cover topics such as the biological and pharmacological basis of chemotherapy; assessing patients and treatment complications; selecting treatments; chemotherapy agents and their use; approaches for specific cancer types; supportive care; and managing side effects, infections, and pain.

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    Handbook of Cancer Chemotherapy: Sixth Edition

    Uploaded by

    Rajesh R
    50 views4 pages
    This document is the sixth edition of the Handbook of Cancer Chemotherapy, which provides an overview of the basic principles, agents used, and treatment approaches for various types of cancer. It is edited by Dr. Roland T. Skeel and contains 31 chapters contributed by experts in oncology. The chapters cover topics such as the biological and pharmacological basis of chemotherapy; assessing patients and treatment complications; selecting treatments; chemotherapy agents and their use; approaches for specific cancer types; supportive care; and managing side effects, infections, and pain.

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    This document is the sixth edition of the Handbook of Cancer Chemotherapy, which provides an overview of the basic principles, agents used, and treatment approaches for various types of cancer. It is edited by Dr. Roland T. Skeel and contains 31 chapters contributed by experts in oncology. The chapters cover topics such as the biological and pharmacological basis of chemotherapy; assessing patients and treatment complications; selecting treatments; chemotherapy agents and their use; approaches for specific cancer types; supportive care; and managing side effects, infections, and pain.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    50 views4 pages

    Handbook of Cancer Chemotherapy: Sixth Edition

    Uploaded by

    Rajesh R
    This document is the sixth edition of the Handbook of Cancer Chemotherapy, which provides an overview of the basic principles, agents used, and treatment approaches for various types of cancer. It is edited by Dr. Roland T. Skeel and contains 31 chapters contributed by experts in oncology. The chapters cover topics such as the biological and pharmacological basis of chemotherapy; assessing patients and treatment complications; selecting treatments; chemotherapy agents and their use; approaches for specific cancer types; supportive care; and managing side effects, infections, and pain.

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    © All Rights Reserved
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    of 4

    Handbook of Cancer

    Chemotherapy
    SIXTH EDITION

    Edited by

    ROLAND T. SKEEL, M.D.


    Professor of Medicine
    Medical College of Ohio
    and
    Chief of Hematology and Oncology
    Department of Medicine
    Medical College Hospital
    Toledo, Ohio

    LiPPiNCOTT WILLIAMS & WILKINS


    A Wolters Kluwer Company
    Philadelphia • Baltimore • New York • London
    Buenos Aires • Hong Kong • Sydney • Tokyo
    Contents
    Contributing Authors ix
    Preface xiii

    Section I.
    Basic Principles and Considerations
    of Rational Chemotherapy
    1. Biologic and Pharmacologic Basis of
    Cancer Chemotherapy 3
    Roland T. Skeel and Samir N. Khleif
    2. Systematic Assessment of the Patient with Cancer
    and Long-Term Medical Complications
    of Treatment 26
    Roland T. Skeel
    3. Selection of Treatment for the Patient
    with Cancer 46
    Roland T. Skeel

    Section II.
    Chemotherapeutic and Biotherapeutic Agents
    and Their Use
    4. Antineoplastic Drugs and Biologic Response
    Modifiers: Classification, Use, and Toxicity
    of Clinically Useful Agents 53
    Roland T. Skeel
    5. High-Dose Chemotherapy with Hematopoietic
    Progenitor Cell and Cytokine Support 157
    Chatchada Karanes

    Section III.
    Chemotherapy of Human Cancer
    6. Carcinomas of the Head and Neck 197
    Ronald C. DeConti
    7. Carcinoma of the Lung 216
    Tien Hoang and Joan H. Schiller
    8. Carcinomas of the Gastrointestinal Tract 231
    Al B. Benson III
    9. Carcinomas of the Pancreas, Liver, Gallbladder,
    and Bile Ducts 255
    Daniel Y. Danso
    vi Contents

    10. Carcinoma of the Breast 269


    Imah Mohamed and Roland T. Skeel
    11. Gynecologic Cancer 294
    C. O. Granai, Walter H. Gajewski,
    Robert D. Legare, and Mary Gordinier
    12. Urologic and Male Genital Malignancies 327
    Scott B. Saxman and Craig R. Nichols
    13. Thyroid and Adrenal Carcinomas 344
    SamirN. Khleif and Haitham S. Abu-Lebdeh
    14. Melanoma and Other Skin Malignancies 360
    Walter D.Y. Quan, Jr.
    15. Primary and Metastatic Brain Tumors 378
    Benjamin E. Lawler and Tracy T. Batchelor
    16. Soft Tissue Sarcomas 389
    Robert S. Benjamin
    17. Bone Sarcomas 400
    Robert S. Benjamin
    18 Acute Leukemias 411
    Andrew M. Evens and Martin S. Tallman
    19. Chronic Leukemias 460
    Peter White
    20. Myeloproliferative and Myelodysplastic
    Syndromes 477
    Peter White
    21. Hodgkin's Disease 489
    Richard S. Stein and David S. Morgan
    22. Non-Hodgkih's Lymphoma 503
    Richard S. Stein and John P. Greer
    23. Multiple Myeloma and Other Plasma
    Cell Dyscrasias 525
    Martin M. Oken
    24. Metastatic Cancer of Unknown Origin 539
    Martin M. Oken
    25. Human Immunodeficiency Virus-Associated
    Malignancies 546
    * Diely A. Pichardo and Jamie H. Von Roenn
    Contents vii

    Section IV.
    Selected Aspects of Supportive Care
    of Patients with Cancer
    26. Side Effects of Cancer Chemotherapy 561
    Janelle M. Tipton
    27. Infections: Etiology, Treatment,
    and Prevention 581
    Neeraja L. Varanasi and Rodger D. MacArthur
    28. Disorders of Hemostasis
    and Transfusion Therapy 603
    Mary R. Smith and NurJehan Stutz
    29. Critical Care Issues in Oncology
    and Bone Metastasis 622
    Roland T. Skeel
    30. Malignant Pleural, Peritoneal, and Pericardial
    Effusions and Meningeal Infiltrates 638
    Walter D.Y. Quan, Jr.
    31. Managing Cancer Pain 650
    Michael J. Fisch and Charles S. Cleeland
    32. Emotional and Psychiatric Problems
    in Patients with Cancer 674
    Kathleen S.N. Franco-Bronson
    and KristiS. Williams

    Appendices
    A. Nomogram for Determining Body Surface Area
    of Adults from Height and Mass 691
    B. Nomogram for Determining Body Surface Area
    of Children from Height and Mass 692
    C. Cancer Screening Recommendations
    for Average Risk, Asymptomatic People
    by the Americaji Cancer Society 693
    D. Selected Oncology Web Sites - Cancer
    and Others 696
    Subject Index 699

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