Plataforma de Lentes

Intraoculares EDOF con diseño

de menisco invertido

Distribuidor oficial en España y Portugal:

 PUBLICACIONES
• Villegas EA, Marín JM, Ginis H, Robles C, Alcón E, Hervella L, Prieto PM, Taña-Rivero P, Artal P. Peripheral Refraction
and Contrast Detection Sensitivity in Pseudophakic Patients Implanted With a New Meniscus Intraocular Lens. J Refract
Surg. 2022 Apr;38(4):229-234. doi: 10.3928/1081597X-20220113-01. Epub 2022 Apr 1. PMID: 35412927.

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 ARVO 2020
Visual simulation to customize depth of focus with new aspheric IOLs
Villegas, Eloy A. ; Ginis, Harilaos S. ; Hervella, Lucía ; Robles, Consuelo ; Prieto, Pedro ; Artal, Pablo

https://iovs.arvojournals.org/article.aspx?articleid=2766637

Purpose: A new type of aspheric intraocular lenses (IOLs) has been designed to increase depth of focus. To account for individual
differences in the patient's eye optics and neural responses, the specific value of spherical aberration of the lens to be implanted needs
to be customized. In this work, we evaluate the performance of a customization procedure using an adaptive optics visual simulator.

Methods: An Adaptive Optics Visual Simulator (VAO, Voptica SL, Murcia, Spain) was used to measure visual acuity (VA) at far,
intermediate (67 cm) and near (33 cm) distances in 6 eyes with paralyzed accommodation. A new aspheric IOL family with four models
having different values of spherical aberration (ArtIOLs, Voptica SL, Murcia, Spain) were used. Inter-subject averages and 95%
confidence intervals (CI), calculated as 1.96*SD, were estimated for all viewing distances.

Results: The mean values of VA at intermediate and near distances improved (from 0.12 to -0.06 at intermediate, from 0.57 to 0.11
LogMAR at near) as asphercity increased while VA at far decreased (from -0.12 to 0.10 LogMAR). However, visual performance for
each lens design depended on each subject with an inter-subject variability of VA, expressed as CI, ranging between 0.05 and 0.2
LogMAR.

Conclusions: A new set of four aspheric IOLs have been designed to obtain different ranges of depth of focus. Each design can
provide quite different visual performance for different subjects at different distances. Preoperative visual simulation using adaptive
optics instruments, such as VAO, would allow selection of the optimum type IOL to customize vision.

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 ESCRS 2020
Intraocular lens to improve peripheral image quality in pseudophakic patients
Artal, Pablo ; Ginis, Harilaos S. ; Villegas, Eloy A. ; Prieto, Pedro ; Marín, Jose M. ; Tañá, Pedro

https://www.escrs.org/amsterdam2020/programme/free-papers-details.asp?id=36955
Purpose: Current intraocular lenses (IOLs) are designed to optimize focus at the eye’s central retina overlooking their performance off
axis. This may be the reason for the worse optical quality in the periphery of the retina in pseudophakic patients compared to the
normal phakic eye (Jaeken et al., IOVS, 2013). There are specific visual tasks where a degraded peripheral optical quality can have a
significant impact in patient's orientation in space and therefore in their safety. In this context, we have designed a new type of IOL to
provide a better off-axis optical quality.

Methods: We applied personalized eye models using anatomical data from normal older eyes to design optimized IOLs in the
peripheral retina. A ray-tracing analysis was used to determine the IOL’s shapes and asphericities that control field curvature and
peripheral astigmatism. Retinal eccentricities of 30, 40 and 50 degrees were used in the optimization process. The lenses were
manufactured and evaluated in a custom-built realistic artificial eye. The images of a point source and extended targets were directly
recorded at various field angles with standard and the new IOLs.

Results: We found a new type of IOLs with an inverted meniscus shape to improve the optical quality in the periphery of the visual field
while remaining of similar quality to standard IOLs on axis. This new IOL has aspheric surfaces with concave-convex shape. The
curvature radius of the posterior surface is smaller than that of the anterior surface by a factor ranging between 2 and 6. A significant
improvement in image quality in the periphery was achieved. These new type of aspheric IOL have four models with different values of
spherical aberration to provide customized depth of focus (ArtIOLs, Voptica SL, Murcia, Spain).

Conclusions: A new IOL designed to control field curvature and to reduce peripheral astigmatism in the pseudophakic eye was
developed. It has an inverted meniscus shape and showed superior image quality in the whole visual field. Further research will be
required to establish how this improvement in optical image quality translates to increased patient`s quality of life.
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 ESCRS 2020
Visual simulation to customize depth of focus with ArtIOL aspheric intraocular lenses

Villegas, Eloy A. ; Robles, Consuelo ; Hervella, Lucia ; Ginis, Harilaos S. ; Marín, Jose M. ; Prieto, Pedro ; Artal, Pablo
https://escrs.conference2web.com/#!contentsessions/58097
Purpose: A new type of aspheric intraocular lenses (IOLs) has been designed to increase depth of focus. To account for individual
differences in the patient's eye optics and neural response, the specific value of spherical aberration of the IOL to be implanted needs
to be customized. We evaluate a customization procedure using an adaptive optics visual simulator.

Methods: An Adaptive Optics Visual Simulator (VAO, Voptica SL, Murcia, Spain) was used to measure visual acuity (VA) at far,
intermediate (80 cm) and near (40 cm) distances in 6 eyes with paralyzed accommodation. A new type of aspheric IOL with four models
having different values of spherical aberration (ArtIOLs, Voptica SL, Murcia, Spain) were simulated. Inter-subject averages and 95%
confidence intervals (CI), calculated as 1.96*SD, were estimated for all viewing distances.

Results: The mean values of VA at intermediate and near distances improved (from 0.06 to -0.05 at intermediate, from 0.62 to 0.12
LogMAR at near) as asphercity increased while VA at far decreased slightly (from -0.11 to -0.01 LogMAR). However, visual
performance for each lens design depended on each subject with an inter-subject variability of VA, expressed as CI, ranging between
0.07 and 0.29 LogMAR.

Conclusions: A new type of aspheric IOLs have been designed to obtain different ranges of depth of focus (ArtIOLs). Each model can
provide quite different visual performance for different subjects at different distances. Preoperative visual simulation using adaptive
optics instruments, such as VAO, would allow selection of the optimum type IOL to customize vision.

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 ARVO 2021
Effects of peripheral refractive errors when negotiating steps
Tabernero, Juan ; Villegas, Eloy A. ; Artal, Pablo
https://iovs.arvojournals.org/article.aspx?articleid=2775778
Purpose: To evaluate the impact of different types of peripheral refractive errors (positive, negative and cylindrical) when subjects perform a functional test of
ascending and descending steps.

Methods: A circular hole subtending 32º over the retina was practiced on the surface of four types of ophthalmic lenses: i) plano lenses (null dioptric power),
ii) positive and negative lenses (±2 D and ±4 D) and iii) oblique cylindrical lenses (+2 D and +3 D) oriented at 45º. The lenses were mounted over standard
frames with the hole aligned to the particular line of sight of six subjects, allowing intact vision across the 32-degree central field and inducing a variety of
refractive errors in the rest of the peripheral visual field. The task for the subjects was to negotiate a floor obstacle consisting of two ascending steps (13 cm
high each), an elevated platform (1 m long) and two descending steps (equal high as the ascending steps). Each subject performed four trials with each
spectacle. A camera equipped with a fish-eye lens captured the movement (at 110 Hz) of the subjects’ feet navigating the obstacle. Two LEDs were attached
to subjects’ shoes to mark the feet trajectories. Kinovea software was used to track the LED trajectories that were exported and analysed using Mathematica
software.

Results: Average navigation times through the obstacle (with respect to the case of plano lenses) were a 15% (SD ±13%) and a 5% (SD ±10%) slower when
subjects wore the +4 D and +2 D lenses respectively. Similarly, with the cylindrical lenses, navigation times were 18±19% (+3 D) and 6±9% (+2 D) slower than
with plano lenses. However, with the -2 D negative lenses, navigation times did not increase with respect to plano lenses (-1±9%) and they barely increased
with the stronger -4 D negative lenses (6±11%). Kinematic analysis of the trajectories showed a more cautious gait approach (more steps, slower gait) and
more foot misplacements when wearing the positive and cylindrical lenses than with negative lenses.

Conclusions: Superimposed positive and cylindrical peripheral refractive errors had instantaneous effects on functional vision when negotiating steps. These
data may be relevant when considering the potential effect in daily activities of increased peripheral refractive errors in cataract patients after implantation of
standard intraocular lenses.

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 ARVO 2021
Less astigmatism and better contrast sensitivity in the periphery of pseudophakic patients implanted with a new
intraocular lens
Artal, Pablo ; Marín, Jose M. ; Ginis, Harilaos S. ; Robles, Consuelo ; Alcón, Encarna ; Villegas, Eloy A. ; Prieto, Pedro ; Tañá-Rivero,
Pedro
https://iovs.arvojournals.org/article.aspx?articleid=2775573
Purpose: The optical quality in the periphery of the retina in pseudophakic patients implanted with standard intraocular lenses (IOLs) is worse than those in the
normal phakic eye (Jaeken et al., IOVS, 2013). This may affect specific visual tasks impacting patient’s orientation in space and therefore in their safety. We have
evaluated peripheral astigmatism and contrast sensitivity in a group of patients implanted with a new type of IOL that was designed to provide better peripheral optics
and compared with a group of patients implanted with a standard IOL.

Methods: A new type of IOL (ArtIOLs, Voptica SL, Murcia, Spain) with an inverted meniscus shape designed to improve the optical quality of the pseudophakic eye in
the periphery was evaluated. These lenses were implanted in a group of 87 patients undergoing cataract surgery. A control group of 38 patients were implanted with a
standard monofocal IOL as reference. Peripheral refraction in the horizontal meridian was measured using a scanning Hartmann-Shack wavefront sensor in every
patient. The contrast detection threshold of the patients at 45 degrees of visual angle was estimated psychophysically by means of an adaptive staircase technique. A
30 arcmin round stimulus located at 1 m of the patient’s eyes was displayed at 45 degrees both horizontal and vertically. A green LED was used as foveal fixation.

Results: Patients implanted with ArtIOLs presented a reduced amount of peripheral astigmatism as compared with the control group. At 30 degrees, the average
cylinder in the control group was 3D, reduced to 2 D in the ArtIOL’s group. At 45 degrees, cylinder were 6 D and 3.5 D respectively. This reduction in astigmatism had
a positive impact in contrast sensitivity. In the horizontal meridian, average sensitivity values were 0.07 (SD=0.04) and 0.10 (SD=0.05) for the control and ArtIOL
groups respectively. In the vertical meridian, average sensitivity values were 0.06 (SD=0.03) and 0.08 (SD=0.03) for the control and ArtIOL groups respectively.

Conclusions: : Patients implanted with a new meniscus-shape IOL present a reduced amount of peripheral astigmatism compared to patients implanted with
standard lenses. This improvement in optical quality lead to a better contrast sensitivity measured at 45 degrees of eccentricity. Further research would be required to
verify how this IOL may have also an impact in patient’s functional vision.

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 ESCRS 2021
A new meniscus IOL provides better contrast sensitivity in the periphery
Artal, Pablo ; Marín, Jose M. ; Ginis, Harilaos S. ; Robles, Consuelo ; Alcón, Encarna ; Villegas, Eloy A. ; Prieto, Pedro ; Tañá-Rivero,
Pedro
https://escrs.conference2web.com/#!resourcegroups/resourcetype_ids=4,15&event_ids=354
Purpose: To evaluate peripheral contrast sensitivity in a group of patients implanted with a new type of IOL that was designed to provide better peripheral
optics and compared results with a group of patients implanted with a standard IOL.
Methods: A new type of IOLs (ArtIOLs, Voptica SL, Murcia, Spain) with an inverted meniscus shape designed to improve the optical quality of the
pseudophakic eye in the periphery were implanted in a group of 87 patients undergoing cataract surgery. A control group of 38 patients were implanted with a
standard monofocal IOL as reference. Peripheral refraction was measured using a scanning Hartmann-Shack wavefront sensor. Contrast detection thresholds
at 45 degrees of visual angle (both horizontally and vertically) were measured psychophysically by means of an adaptive staircase technique, using a 30-
arcmin round stimulus 1 m in front of the patient’s eyes.
Results: Patients implanted with ArtIOLs presented a reduced peripheral astigmatism as compared with the control group. At 30 degrees, the average
cylinder in the control group was 3 D, dropping to 2 D in the ArtIOL’s group. At 45 degrees, cylinder mean values were 6 D and 3.5 D respectively. In the
horizontal meridian, average contrast sensitivity values were 0.07 (SD=0.04) and 0.10 (SD=0.05) for the control and ArtIOL groups respectively. In the vertical
meridian, average sensitivity values were 0.06 (SD=0.03) and 0.08 (SD=0.03) for the control and ArtIOL groups respectively. In both directions the differences
were statistically significant.

Conclusions: Patients implanted with a new meniscus-shaped IOL present a reduced amount of peripheral astigmatism compared to patients implanted with
standard lenses. This improvement in optical quality leads to a better contrast sensitivity measured at 45 degrees of eccentricity.

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 ESCRS 2021
Refractive outcomes and safety of a new meniscus IOL designed to improve peripheral vision
Villegas, Eloy A. ; Robles, Consuelo ; Alcon, Encarna ; Hervella, Lucia ; Marín, Jose M. ; Taña-Rivero, Pedro ; Artal, Pablo

https://escrs.conference2web.com/#!contentsessions/58097
Purpose: A new type of inverted meniscus IOL with convex surface facing the retina and aspheric surfaces (Art25, Voptica SL, Murcia, Spain) has been
designed to improve peripheral optics providing better contrast sensitivity. We performed a study to evaluate the refractive outcomes, visual acuity and
adverse events after Art25 implantation.
Methods: A group of 250 eyes of 171 patients with preoperative corneal astigmatism equal or below 1.5 D were implanted with Art25 IOL. From optical
biometric measurements with IOL Master (Carl Zeiss), IOL power was estimated using the SKT formula, with A-constant of 120, targeting a postoperative
refraction of emmetropia. For every patient, detailed measurements were performed at one month after cataract surgery: objective and subjective refraction,
best corrected visual acuity (VA), slit-lamp biomicroscopy, intraocular pressure, corneal topography and retinography.
Results: Average refractive outcomes were -0.10 ±0.40 D, range [-0.75, +0,50], for spherical equivalent and 0.68±0.40 D, range [0.00, 1.50], for astigmatism.
Best corrected VA was equal or better than 0.0 LogMAR in 95% of the eyes, all better than 0.2 LogMAR. No surgery complications were noted during the
Art25 implantation and no adverse events were reported at one-month follow-up except one posterior capsular opacification.
Conclusions: The implantation of Art25 IOL provided null or small refractive errors and excellent visual acuity with a level of safety like any standard IOL.

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 ARVO 2022

Inverted meniscus IOLs reduce retinal distortion in the peripheral visual field

Robles, Consuelo; Prieto, Pedro ; Marín, Jose M. ; Alcón, Encarna ; Tañá-Rivero, Pedro; Hervella, Lucía; Christaras, Dimitrios;
Ginis, Harilaos S. ; Artal, Pablo
Purpose: Standard biconvex intraocular lenses (IOLs) are designed to optimize focus at the eye’s central retina but degrade optical quality in the peripheral retina
with respect to the natural crystalline lens. In order to prevent this drawback of current IOLs, a new lens with an inverted meniscus shape (ArtIOL, Voptica SL, Murcia,
Spain) was developed to provide better image quality in the peripheral retina. Moreover, IOL implantation can be associated with image distortion. The aim of this
study is to compare the inverted meniscus lenses with the standard biconvex with respect to the induced image distortion.

Methods: Pre- and post- cataract surgery fundus images were taken with an ultra-widefield retinal camera(CLARUS 500, Zeiss, Germany) in 55 eyes of patients
implanted with a standard biconvex IOL (control group)and 43 eyes of patients implanted with the inverted meniscus ArtIOL lens. For each eye, retinal
landmarks(such as vessel bifurcations) were identified and their relative radial position was identified using a purposely written MATLAB (MathWorks, Inc. Natick, MA,
USA) script. Retinal distortion at these locations was obtained for both groups.

Results: Although there was a large variability among subjects, we have found distortion to be significantly lower in the ArtIOL group than in the control group.
Furthermore, distortion was found to linearly increase with eccentricity roughly twice faster in the control group than in the ArtIOL group (see figure), therefore
predicting even larger differences for higher eccentricities than the 40 deg range studied.

Conclusions: Its inverted meniscus design bestow ArtIOL lenses with a better performance on the peripheral field, significantly reducing distortion of the retinal
image in pseudophakic eyes with respect to traditional biconvex IOLs. This may have an impact in the quality of vision affecting patients’ tasks relaying in peripheral
performance.

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 ARVO 2022
BINOCULARLY EXTENDED DEPTH OF FOCUS WITH A NEW INVERTED MENISCUS IOL
Eloy Villegas, José Maria Marin, Consuelo Robles, Lucia Hevella, Encarna Alcon, Pedro Prieto, Pedro Taña, Harilaos Ginis and
Pablo Artal
Purpose: To evaluate the depth of focus induced by a binocular combination of two different models of a new inverted meniscus intraocular lens (IOL), Art40 and
Art70 (ArtIOLs, Voptica SL, Murcia, Spain). The two lenses improve the overall off-axis optical quality and induce different amounts of negative spherical aberration.

Methods: Six cataract patients were implanted bilaterally with Art40 and Art70 IOLs to induce low and high values of spherical aberration respectively. The surgery
was performed first in the dominant eye with Art40 and a few weeks later in the fellow eye with Art70. As control group, nine patients were bilaterally implanted with a
standard monofocal IOL based on aspherical biconvex optics. One month after the last surgery, best-corrected (CDVA) and uncorrected (UDVA) distance visual acuity
(LogMAR scale) was measured at 5 m, 66 cm and 40 cm, using trial lenses of -1,5 and -2,5 D and SLOAN charts under photopic lighting conditions.

Results: The monocular CDVA was on average zero in the three groups (eyes implanted with Art40, Art70 models and standard IOLs). In the control group, it
decreased rapidly to around 0.25 and 0.43 at intermediate and near distances. In the eyes with Art40, the deterioration was slower to 0.18 and 0.35, while in the eyes
with Art70 those values were still better, 0.11 and 0.27. The binocular combination of Art40 and Art70 yielded mean CDVA values of -0.02, 0.01 and 0.12 at far,
intermediate and near distances respectively. With the two models of the inverted meniscus lenses, small myopic residual errors were planned (-0.25 and -0.75 D for
Art40 and Art70 respectively). As shown in figure, the mean values of binocular UCVA with ArtIOLs were -0.02, 0.01 and 0.06 and in the control group 0.02, 0.17 and
0.39 at 5 m, 66 cm and 40 cm. Inter-subject variability, estimated as standard deviation, ranged between 0.04 and 0.13.

Conclusions: In addition to the optical improvement in the periphery due to the inverted meniscus shape, the binocular combination of the two of ArtIOLs models
(Art40 and Art70) improved significantly the useful range of distances. This combination resulted in spectacle independence for the patients without the compromise
of halo or disphotopsias.

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 ESCRS 2022
Visual Performance of a new Extended Depth-Of-Focus IOL with Inverted Meniscus design

Inés Yago, Jose Maria Marin, Encarna Alcón, Consuelo Robles, Lucía Hervella Ginestá, Eloy Villegas, Pedro Prieto, Harilaos Ginis, Pablo Artal; Visual
performance of a new extended Depth-of-focus IOL with inverted meniscus design. ESCRS 2022

Purpose: To evaluate the visual performance at different distances of a Results: !2"$-:#:%;.&($EFG3$,&+$:#$&="(&<"$R"(:$*#$'2"$'2(""$<(:;)+$D"1"+$

binocular combination of two models of a new inverted meniscus *-).&#'"/$,*'2$3('45?$3('65$-:/".+$&#/$'(*>:%&.$789+H@$7#$'2"$'(*>:%&.$<(:;)?$*'$
intraocular lens (IOL), Art40 and Art70 (ArtIOLs, Voptica SL, Murcia, Spain) /"%("&+"/$':$&(:;#/$5@N5$&'$0:'2?$*#'"(-"/*&'"$&#/$#"&($/*+'&#%"+@$7#$'2"$"1"+$
which improve the overall off-axis optical quality and induce different ,*'2$3('45?$'2"$EFG3$>"..$':$5@OL$&#/$5@46?$,2*."$*#$'2"$"1"+$,*'2$3('65$'2:+"$
amounts of negative spherical aberration to increase the depth of focus. =&.;"+$("-&*#"/$-;%2$2*<2"(?$5@5S$&#/$5@ON@$!2"$0*#:%;.&($%:-0*#&'*:#$:>$
The outcomes were compared with those of diffractive trifocal IOLs. 0:'2$3('789+ *-)(:="/$'2"$EFG3$;)$':$5@5O$>:($*#'"(-"/*&'"$&#/$5@NL$>:($#"&($
=*+*:#@$T*'2$'2"$',:$-:/".+$:>$'2"$*#="('"/$-"#*+%;+$."#+"+?$+-&..$-1:)*%$
Methods: !"#$%&'&(&%'$)&'*"#'+$,"("$*-).&#'"/$0*.&'"(&..1$,*'2$3('45$&#/$ ("+*/;&.$"((:(+$,"("$).&##"/$DC5@OL$&#/$C5@6L$F$>:($3('45$&#/$3('65?$
3('65$789+$':$*#/;%"$.:,$&#/$2*<2$=&.;"+$:>$+)2"(*%&.$&0"((&'*:#?$ ("+)"%'*=".1H@$!2"$-"&#$=&.;"+$:>$0*#:%;.&($IEG3$,*'2$3('789+ ,"("$5?$5@5O$
("+)"%'*=".1@$!2"$+;(<"(1$,&+$)"(>:(-"/$>*(+'$*#$'2"$/:-*#&#'$"1"$,*'2$ &#/$5@5L$&#/$*#$'2"$'(*>:%&.$<(:;)$5@5L?$5@5U$&#/$5@5V$&'$L$-?$MM$%-$&#/$45$%-@
3('45$&#/$&$>",$,""A+$.&'"($*#$'2"$>"..:,$"1"$,*'2$3('65@$3+$'(*>:%&.$<(:;)?$
'"#$)&'*"#'+$,"("$0*.&'"(&..1$*-).&#'"/$,*'2$&$+'&#/&(/$'(*>:%&.$789+$0&+"/$ Conclusions: !2"$0*#:%;.&($%:-0*#&'*:#$:>$'2"$',:$:>$3('789+ -:/".+$D3('45$
:#$&+)2"(*%&.$0*%:#="B$:)'*%+@$8#"$-:#'2$&>'"($'2"$.&+'$+;(<"(1?$0"+'C &#/$3('65H$+*<#*>*%&#'.1$"B'"#/"/$'2"$/")'2$:>$>:%;+$;)$':$&'$."&+'$45$%-$
%:(("%'"/$DEFG3H$&#/$;#%:(("%'"/$DIFG3H$/*+'&#%"$=*+;&.$&%;*'1$ *-)(:=*#<$=*+;&.$)"(>:(-&#%"$&'$*#'"(-"/*&'"$/*+'&#%"$*#$%:-)&(*+:#$,*'2$
D9:<J3K +%&."H$,&+$-"&+;("/$&'$L$-?$MM$%-$&#/$45$%-?$;+*#<$'(*&.$."#+"+$ '(*>:%&.$978+@$!2*+$%:-0*#&'*:#$("+;.'"/$*#$+)"%'&%."$*#/")"#/"#%"$>:($'2"$
:>$CN?L$&#/$CO?L$F$&#/$P983Q$%2&('+$;#/"($)2:':)*%$.*<2'*#<$%:#/*'*:#+@ )&'*"#'+$,*'2:;'$'2"$%:-)(:-*+"$:>$2&.:+$:($/*+)2:':)+*&+@$7#$&//*'*:#?$'2"+"$
#",$789+$*-)(:="$'2"$)"(*)2"(1$)"(>:(-&#%"$/;"$':$'2"$*#="('"/$-"#*+%;+$
+2&)"@

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 ESCRS 2022
Spectacle Independence and Subjective Quality of Vision after Binocular Implantation of a New
Extended Depth-Of-Focus IOL with Inverted Meniscus Design
Lucia Hervella, Eloy A. Villegas, Jose Maria Marin, Encarna Alcón, Consuelo Robles, Laura Montesinos, Pedro Prieto, Harilaos Ginis, Pablo Artal;
Spectacle Independence and subjective quality of vision after binocular implantation of a new extended Depth-of-focus IOL with inverted meniscus design.
ESCRS 2022

Purpose: To assess the spectacle’s independence and subjective quality Results: !2"$0*#:%;.&($%:-0*#&'*:#$:>$'2"$',:$."#+"+$)(:=*/"/$-"&#$=&.;"+$:>$
of vision perceived by pseudophakic patients implanted bilaterally with a ;#%:(("%'"/$=*+;&.$&%;*'1$:>$5@55$9:<J3K &'$>&($&#/$0"''"($'2&#$5@5L$9:<J3K
combination of two models of a new inverted meniscus intraocular lens &'$*#'"(-"/*&'"$DMM$%-H$&#/$#"&($D45$%-H$/*+'&#%"+@$!2"$WKP7X$("+;.'+$
(IOL), Art40 and Art70 (ArtIOLs, Voptica SL, Murcia, Spain) which improve +2:,"/$'2&'$U$:>$'2"$N5$)&'*"#'+$/*/#Y'$;+"$<.&++"+$>:($>&($&#/$*#'"(-"/*&'"$
the overall off-axis optical quality and induce different amounts of negative '&+A+$&#/$V$)&'*"#'+$/*/#Y'$;+"$<.&++"+$&'$#"&($/*+'&#%"@$Z(:-$X:G +;(="1+?$>:($
spherical aberration to increase the depth of focus. "&%2$+1-)':-?$V$:($-:("$)&'*"#'+$#"="($("):('"/$'2&'$+1-)':-?$&#/$,2"#$
'2"1$/*/?$'2"$."=".+$:>$+"="(*'1$&#/$0:'2"(+:-"$,"("$.:,@$8#.1$:#"$)&'*"#'$
Methods: Ten cataract patients were implanted bilaterally with Art40 and ("):('"/$<.&("$&#/$2&.:+$0;'$,*'2$.:,$*-)&%'$*#$2*+$/&*.1$'&+A+@
Art70 IOLs to induce low and high values of negative spherical aberration
respectively. In addition to the measurements of visual acuity at different Conclusions: Most patients implanted with the bilateral combination of Art40
distances, 1-3 months after the last surgery, patients were surveyed for the and Art70 IOLs were spectacle independent
spectacle independence at different distances using the Patient Reported for all daily activities and all viewing distances. Given the refractive nature of
Spectacle Independence Questionnaire (PRSIQ) and for the frequency, these IOLs the patients did not report any
severity and bothersome (with four levels of score) of 10 negative visual relevant negative visual symptoms.
symptoms (glare, haloes, starburst, etc.) using the Quality of Vision (QoV)
questionnaire.

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 ESCRS 2022
A New Inverted Meniscus IOL Reduces Retinal Distortion in the Periphery

Consuelo Robles, Pedro Prieto, Jose Maria Marin, Encarna Alcón, Pedro Taña-Rivero, Lucía Hervella, Dimitrios Christaras, Harilaos S Ginis, Pablo Artal; A
new inverted meniscus IOL reduced retinal distortion in the periphery. ESCRS 2022

Purpose: Traditionally IOLs have been designed to optimize central retina, Results: F*+':('*:#$2&+$0""#$>:;#/$':$0"$+*<#*>*%&#'.1$.:,"($*#$'2"$3('789 <(:;)$
but degrade optical quality in the periphery due to its biconvex shape. In '2&#$*#$'2"$%:#'(:.$:#"@$Z;('2"(-:("?$/*+':('*:#$,&+$>:;#/$':$*#%("&+"$,*'2$
order to improve image quality in the peripheral retina, a new inverted "%%"#'(*%*'1$-;%2$>&+'"($>:($0*%:#="B$789$'2&#$*#$'2"$3('789 :#"?$)("/*%'*#<$
meniscus IOL was developed (ArtIOL, Voptica SL,Murcia, Spain). On the "="#$.&(<"($/*>>"("#%"+$>:($2*<2"($"%%"#'(*%*'*"+@
other hand, IOL implantation can be associated with image distortion. This
study compares the induced image distortion of standard biconvex IOL with Conclusions: F;"$':$*'+$*#="('"/$-"#*+%;+$+2&)"$3('789+ 2&="$0"''"($
inverted meniscus lenses. )"(>:(-&#%"$:#$'2"$)"(*)2"(&.$>*"./@$3.'2:;<2$-&*#.1$/"+*<#"/$':$*-)(:="$:>>$
&B*+$/">:%;+?$'2"1$2&="$&.+:$0""#$>:;#/$':$("/;%"$("'*#&.$*-&<"$/*+':('*:#$*#$
Methods: Z;#/;+$*-&<"+$)("C &#/$):+'C %&'&(&%'$+;(<"(1$,"("$'&A"#$,*'2$ )+";/:)2&A*% "1"+$,*'2$("+)"%'$':$'(&/*'*:#&.$0*%:#="B$789+@$!2*+$>&%'$-&1$
&#$;.'(&C,*/">*"./$("'*#&.$%&-"(&$DE93KIP$L55?$["*++?$\"(-&#1H$*#$4S$ 2&="$&#$*-)&%'$:#$'2"$)"(>:(-&#%"$:>$)+";/:)2&A*% +;0^"%'+$,2"#$%:#>(:#'"/$
"1"+$*-).&#'"/$,*'2$3('789 &#/$LL$"1"+$*-).&#'"/$,*'2$&$+'&#/&(/$ ,*'2$/&*.1$'&+A+?$+;%2$&+$/(*=*#<$:($+'&*($%.*-0*#<?$'2&'$*#=:.="$)"(*)2"(&.$=*+*:#@
0*%:#="B$789$D%:#'(:.$<(:;)H@$K"'*#&.$.&#/-&(A+$+;%2$&+$="++".$
0*>;(%&'*:#+$,"("$*/"#'*>*"/$>:($"&%2$"1"$&#/$'2"*($(".&'*="$(&/*&.$):+*'*:#$
,&+$/"'"(-*#"/$;+*#<$&$J3!93]$DJ&'2T:(A+?$7#%@$Q&'*%A?$J3?$IP3H$
+%(*)'@$K"'*#&.$/*+':('*:#$;)$':$>:('1$/"<(""+$,&+$:0'&*#"/$>:($0:'2$<(:;)+@

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 ESCRS 2022
Influence of Peripheral Refractive Errors on Driving Perfomance

Sonia Ortiz, Mirian Casares, Rosario Gonzalez, Jose María Marín Pablo Artal; Influence of peripheral refractive errors on driving performance. ESCRS 2022.

Purpose: Cataract surgery and intraocular lens implantation may alter Results: Driving performance was significantly impaired by the addition of
peripheral optics due to changes in peripheral refractive error. Driving is a peripheral refractive myopic defocus of 4D and 4D of astigmatism. One of the
highly demanding visual task that could be affected by these changes. Thus, most affected aspects was the ability to maintain the vehicle's position within
this study aimed to investigate the influence of additional peripheral refractive the lane. When interacting with the Google Maps task, the impairment in driving
errors on driving performance. performance was greater than for the route in general (all tasks). Worse driving
performance was significantly correlated with worse peripheral contrast
Methods: Thirty-one young drivers were included in the study. Driving sensitivity, but also with worse peripheral visual acuity when participants were
performance was assessed by means of a driving simulator. Participants were performing Google Maps tasks.
induced different additional peripheral refractive errors using ophthalmic
lenses that allowed normal central binocular vision. Thus, they drove under 7 Conclusions: Driving performance is affected by peripheral refractive changes
experimental conditions: baseline session (0D), with spheres of +/- 2D and +/- when performing secondary visual-manual tasks. The impairment is associated
4D (hyperopic and myopic defocus), and with cylinders of +2D and +4D with peripheral contrast sensitivity and visual acuity. These results have
oriented at 180° (astigmatism). While driving, participants had to interact with a implications for patients undergoing procedures such as cataract surgery given
touch screen at 40° to perform two tasks: searching for traffic signs through a that peripheral optical quality of eyes implanted with IOL will be modified.
document and typing an address on Google Maps. Peripheral visual acuity
and peripheral contrast sensitivity were measured at the same eccentricity.

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