Hip Fracture Management PDF 35109449902789
Hip Fracture Management PDF 35109449902789
Hip Fracture Management PDF 35109449902789
Clinical guideline
Published: 22 June 2011
Last updated: 6 January 2023
www.nice.org.uk/guidance/cg124
Your responsibility
The recommendations in this guideline represent the view of NICE, arrived at after careful
consideration of the evidence available. When exercising their judgement, professionals
and practitioners are expected to take this guideline fully into account, alongside the
individual needs, preferences and values of their patients or the people using their service.
It is not mandatory to apply the recommendations, and the guideline does not override the
responsibility to make decisions appropriate to the circumstances of the individual, in
consultation with them and their families and carers or guardian.
All problems (adverse events) related to a medicine or medical device used for treatment
or in a procedure should be reported to the Medicines and Healthcare products Regulatory
Agency using the Yellow Card Scheme.
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Contents
Overview ................................................................................................................................... 4
Recommendations .................................................................................................................... 5
2 Anaesthesia ..................................................................................................................................... 14
Context ...................................................................................................................................... 22
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Overview
This guideline covers managing hip fracture in adults. It aims to improve care from the time
people aged 18 and over are admitted to hospital through to when they return to the
community. Recommendations emphasise the importance of early surgery and
coordinating care through a multidisciplinary Hip Fracture Programme to help people
recover faster and regain their mobility.
NICE has also produced a guideline on osteoporosis: assessing the risk of fragility fracture.
Who is it for?
• Healthcare professionals
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Recommendations
People have the right to be involved in discussions and make informed decisions
about their care, as described in NICE's information on making decisions about your
care.
Making decisions using NICE guidelines explains how we use words to show the
strength (or certainty) of our recommendations, and has information about
prescribing medicines (including off-label use), professional guidelines, standards
and laws (including on consent and mental capacity), and safeguarding.
Some aspects of hip fracture management are already covered by NICE guidance and are
therefore outside the scope of this guideline. To ensure comprehensive management and
continuity, the following NICE guidance should be referred to when developing a complete
programme of care for each patient:
• NICE guidelines on falls in older people, pressure ulcers, nutrition support for adults,
dementia, surgical site infections, venous thromboembolism in over 16s, delirium and
osteoporosis: assessing the risk of fragility fracture.
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• anaemia
• anticoagulation
• volume depletion
• electrolyte imbalance
• uncontrolled diabetes
1.3 Analgesia
1.3.1 Assess the person's pain:
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1.3.5 Offer additional opioids if paracetamol alone does not provide sufficient
preoperative pain relief. [2011]
1.3.6 Consider adding nerve blocks if paracetamol and opioids do not provide
sufficient preoperative pain relief, or to limit opioid dosage. Nerve blocks
should be administered by trained personnel. Do not use nerve blocks as
a substitute for early surgery. [2011]
1.3.8 Offer additional opioids if paracetamol alone does not provide sufficient
postoperative pain relief. [2011]
1.4 Anaesthesia
1.4.1 Offer people a choice of spinal or general anaesthesia after discussing
the risks and benefits. [2011]
1.4.2 Consider intraoperative nerve blocks for all people undergoing surgery.
[2011]
1.5.2 Consultants or senior staff should supervise trainee and junior members
of the anaesthesia, surgical and theatre teams when they carry out hip
fracture procedures. [2011]
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1.6.3 Consider total hip replacement rather than hemiarthroplasty for people
with a displaced intracapsular hip fracture who:
• were able to walk independently out of doors with no more than the use of a
stick and
• do not have a condition or comorbidity that makes the procedure unsuitable for
them and
For a short explanation of why the committee made the 2023 recommendation and
how it might affect practice, see the rationale and impact section on total hip
replacement versus hemiarthroplasty.
Full details of the evidence and the committee's discussion are in evidence review B:
total hip replacement versus hemiarthroplasty.
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For a short explanation of why the committee made the 2023 recommendations and
how they might affect practice, see the rationale and impact section on femoral
component design used for hemiarthroplasties.
Full details of the evidence and the committee's discussion are in evidence review A:
femoral component design used for hemiarthroplasties.
1.7.2 Offer people mobilisation at least once a day and ensure regular
physiotherapy review. [2011]
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• orthogeriatric assessment
• clinical and service governance responsibility for all stages of the pathway of
care and rehabilitation, including those delivered in the community. [2011]
1.8.3 Healthcare professionals should deliver care that minimises the person's
risk of delirium and maximises their independence, by:
• actively looking for cognitive impairment when people first present with hip
fracture
• reassessing people to identify delirium that may arise during their admission
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• has not yet achieved their full rehabilitation potential, as discussed with the
person, carer and family. [2011]
• the Hip Fracture Programme team retains the clinical lead, including patient
selection, agreement of length of stay and ongoing objectives for intermediate
care and
• the Hip Fracture Programme team retains the managerial lead, ensuring that
intermediate care is not resourced as a substitute for an effective acute
hospital programme. [2011]
1.8.6 People admitted from care or nursing homes should not be excluded
from rehabilitation programmes in the community or hospital, or as part
of an early supported discharge programme. [2011]
• diagnosis
• choice of anaesthesia
• surgical procedures
• possible complications
• postoperative care
• rehabilitation programme
• long-term outcomes
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The 2011 committee's full set of recommendations for research are detailed in the full
guideline.
As part of the 2017 update, the standing committee removed the recommendation for
research on displaced intracapsular hip fractures and made an additional recommendation
for research on undisplaced intracapsular hip fractures. Full details are available in section
3.5 of the full guideline addendum.
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2 Anaesthesia
What is the clinical and cost effectiveness of regional versus general anaesthesia on
postoperative morbidity in people with hip fracture?
A qualitative research component would also be helpful to study patient preference for
type of anaesthesia. [2011]
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The committee also noted a paucity of evidence for 2 of the interventions (total hip
replacement and hemiarthroplasty) that could potentially be useful for people with
undisplaced intracapsular hip fracture. A randomised controlled trial comparing these
interventions would be beneficial. [2017]
The ideal study design is a randomised controlled trial. Initial studies may have to focus on
proof of concept and be mindful of costs. A phase 3 randomised controlled trial is required
to determine clinical effectiveness and cost effectiveness. The ideal sample size will be
around 400 to 500 patients, and the primary outcome should be physical function and
health-related quality of life. Outcomes should also include falls. A formal sample size
calculation will need to be undertaken. Outcomes should be followed over a minimum of
1 year, and compare if possible, either the recovery curve for restoration of function or
time to attainment of functional goals. [2011]
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Given the patient frailty and comorbidities, rehabilitation may have no effect on clinical
outcomes for this group. However, the fact that they already live in a home where they are
supported by trained care staff clearly provides an opportunity for a systematic approach
to rehabilitation. Early multidisciplinary rehabilitation based in care homes or nursing
homes would take advantage of the day-to-day care arrangements already in place and
provide additional NHS support to deliver naturalistic rehabilitation, where problems are
tackled in the person's residential setting.
Early supported multidisciplinary rehabilitation could reduce hospital stay, improve early
return to function, and affect both readmission rates and the level of NHS-funded nursing
care required.
The research would follow a 2-stage design: (1) an initial feasibility study to refine the
selection criteria and process for reliable identification and characterisation of those
considered most likely to benefit, together with the intervention package and measures for
collaboration between the Hip Fracture Programme team, care-home staff and other
community-based professionals and (2) a cluster randomised controlled comparison (for
example, with 2 or more intervention units and matched control units) set against agreed
outcome criteria. The latter should include those specified above, together with measures
of the impact on care-home staff activity and cost, as well as qualitative data from
patients on relevant quality-of-life variables. [2011]
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For a short explanation of why the committee made this recommendation for
research, see the rationale section on total hip replacement versus hemiarthroplasty.
Full details of the evidence and the committee's discussion are in evidence review B:
total hip replacement versus hemiarthroplasty.
For a short explanation of why the committee made this recommendation for
research, see the rationale section on femoral component design used for
hemiarthroplasties.
Full details of the evidence and the committee's discussion are in evidence review A:
femoral component design used for hemiarthroplasties.
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Based on their clinical knowledge and experience, the committee discussed how the long-
term outcomes considered in the health economic model were important but may not be
relevant to some people. For example, older people may not live long enough to
experience the long-term benefits of total hip arthroplasty, and people who are not very
mobile may be less concerned about the potential consequences of having a
hemiarthroplasty, such as wear on the acetabulum. The committee agreed that
hemiarthroplasty was a less complicated procedure than total hip arthroplasty and could
result in lower dislocation rates and less blood loss.
The health economic evidence on the long-term cost effectiveness and potential clinical
benefits of total hip arthroplasty led the committee to recommend that clinicians should
consider the procedure for those who are most likely to benefit from it beyond 2 years.
The list of criteria in the recommendation represents the past (a person's level of
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independence before the fracture), present (how they currently present in hospital and if
they are fit for the procedure on that day) and future (how much they are likely to benefit
beyond 2 years). Including this list gives clinicians more discretion over who to offer total
hip arthroplasty to and prevents the procedure being offered to some people who may get
the same, or more, benefit from hemiarthroplasty.
The committee discussed how some people with significant cognitive impairments may be
at increased risk of dislocations and could be less likely to benefit from total hip
arthroplasty. However, they agreed that the evidence for this was too limited to make a
specific recommendation for this population. The risk of dislocation can also vary
depending on the severity and type of cognitive impairment, or how much support the
person has. They agreed that cognitive impairment is one of many important comorbidities
that should be considered when making treatment decisions. It is more important for
clinicians to think about comorbidities in the context of functionality rather than whether
or not a person has them. The committee also agreed that decisions about whether
someone is likely to benefit most from total hip arthroplasty or hemiarthroplasty would
normally be made as part of a multidisciplinary team.
The committee discussed the potential long-term benefit of total hip arthroplasty in
specific groups of people, in particular younger age groups with fewer or less severe
comorbidities. As the evidence did not provide much long-term data, and results were not
reported for different age categories, it was agreed that further research should be carried
out to inform future recommendations. A recommendation for research on long-term
effectiveness of total hip replacement was therefore included to highlight the importance
of comparing the effectiveness of total hip arthroplasty with hemiarthroplasty in the long
term and determining the effect of each type of arthroplasty on different population
subgroups.
Return to recommendation
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The Thompson component was cheaper than the ETS or Exeter/Unitrax component, but
the committee were aware of future regulatory changes requiring data about implants,
meaning that some older designs are unlikely to be used in the future. Without further
evidence on other cemented components currently in use, they were unable to
recommend one femoral component over another.
To choose the most cost-effective option, the committee agreed it was important for
hospitals to consider not only the cost of the component itself, but also the cost of training
needs when switching to a new component, alongside any future costs relating to adverse
outcomes. There may also be other considerations, in addition to costs. For example,
some hospitals may choose to use a femoral component that is suitable for both
hemiarthroplasty and total hip arthroplasty to allow consistency and greater efficiency in
practice. The committee thought it was important from a training and development
perspective that medical teams become familiar with implanting 1 single type of
component as standard. They agreed that more research was needed on the effectiveness
of different components.
The committee agreed that although the observational evidence was for femoral
components not used in the UK, it did emphasise the importance of registry data in
exploring longer-term adverse outcomes such as periprosthetic fracture in trauma patients
who had undergone hemiarthroplasty. Recording data on hemiarthroplasties for
submission to a national registry, such as the National Joint Registry, will help to provide
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real-world data on the long-term effectiveness and safety of different femoral components
in trauma patients.
The committee commented that the 2011 recommendation to use a proven femoral
component design (based on Orthopaedic Device Evaluation Panel ratings) came from
evidence of people having elective surgery. They queried whether femoral component
designs for elective patients who have arthritis were appropriate for trauma patients, given
that arthritis often puts people at greater risk of fractures. Therefore, the committee
drafted a recommendation for research on femoral component design that would allow
data for this fragility fracture population to be captured. Registry data could also be used
to evaluate long-term effectiveness in specific subpopulations such as people from
different ethnic backgrounds and other groups for which there is currently no evidence.
The National Joint Registry already collects data on total hip arthroplasties. Collecting data
on hemiarthroplasties in this, or a similar database, may require some extra administrative
work. But the real-world data will be valuable in helping future decision makers choose the
most clinically and cost-effective femoral component. Having further research on the
effectiveness of different femoral components in people from different population groups
will also help inform decisions and address health inequalities in this area.
Return to recommendations
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Context
Hip fracture refers to a fracture occurring in the area between the edge of the femoral
head and 5 cm below the lesser trochanter (see figure 1 in the full guideline). These
fractures are generally divided into 2 main groups. Those above the insertion of the
capsule of the hip joint are termed intracapsular, subcapital or femoral neck fractures.
Those below the insertion are extracapsular. The extracapsular group is split further into
trochanteric (inter- or pertrochanteric and reverse oblique) and subtrochanteric.
Hip fracture is a major public health issue due to an ever-increasing ageing population.
About 65,000 hip fractures occur each year and the annual cost (not including the
considerable cost of social care) for all UK hip fracture cases is about £1 billion. About 10%
of people with a hip fracture die within 1 month and about one-third within 12 months.
Most of the deaths are due to associated conditions and not to the fracture itself,
reflecting the high prevalence of comorbidity. Because the occurrence of fall and fracture
often signals underlying ill health, a comprehensive multidisciplinary approach is required
from presentation to subsequent follow-up, including the transition from hospital to
community.
This guideline covers the management of hip fracture from admission to secondary care
through to final return to the community and discharge from specific follow-up. It assumes
that anyone clinically suspected of having a hip fracture will normally be referred for
immediate hospital assessment. It excludes (other than by cross-reference) aspects
covered by parallel NICE guidance, most notably primary and secondary prevention of
fragility fractures, but recognises the importance of effective linkage to these closely
related elements of comprehensive care. Although hip fracture is predominantly a
phenomenon of later life (the National Hip Fracture Database reports the average age of a
person with hip fracture as 84 years for men and 83 for women), it may occur at any age in
people with osteoporosis or osteopenia, and this guidance is applicable to adults across
the age spectrum. Management of hip fracture has improved through the research and
reporting of key skills, especially by collaborative teams specialising in the care of older
people (using the general designation 'orthogeriatrics'). These skills are applicable in hip
fracture irrespective of age, and the guidance includes recommendations that cover the
needs of younger people by drawing on such skills in an organised manner.
Although not a structured service delivery evaluation, the Guideline Development Group
was required to extend its remit to cover essential implications for service organisation
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within the NHS where these are fundamental to hip fracture management, and this has
been done.
The NICE surveillance review identified new studies that were consistent with the current
recommendations. However, because of a low level of compliance (around 30% nationally)
with the recommendation to offer total hip replacement to people with displaced
intracapsular hip fractures, we have updated this part of the guideline. The 2017 update
also covers interventions for undisplaced intracapsular hip fractures, which were not
covered in the original guideline.
The guideline will assume that prescribers will use a drug's summary of product
characteristics to inform decisions made with individual patients.
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For full details of the evidence and the guideline committee's discussions, see the full
guideline, addendum and evidence reviews. You can also find information about how the
guideline was developed, including details of the committee.
NICE has produced tools and resources to help you put this guideline into practice. For
general help and advice on putting our guidelines into practice, see resources to help you
put NICE guidance into practice.
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Update information
January 2023: We have reviewed the evidence for the management of intracapsular hip
fracture and femoral component design used for hemiarthroplasties, and updated our
recommendations. These recommendations are marked [2023]. We also made 2 new
recommendations for research.
In some cases, minor changes have been made to the wording of other recommendations
to bring the language and style up to date, without changing the meaning. We also made a
clarification in recommendation 1.6.9 because of changes to the AO classification. This is
marked [2011, amended 2023] and it last had an evidence review in 2011.
May 2017: Recommendations have been updated on the surgical management of hip
fracture. These are marked as [2017]. A link was added to recommendation 1.6.4 on
cemented implants to highlight safety guidance.
Where recommendations end [2011] or [2011, amended 2014], the evidence has not been
reviewed since the original guideline.
March 2014: The introduction to the full guideline and the wording of recommendation 1.1.1
have been amended to clarify how an occult fracture is identified and when an MRI scan
should be done.
ISBN: 978-1-4731-4923-6
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Accreditation
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