Scribd Logo
Upload

Welcome to Scribd!

  • 5 views

    GUID - 1 en-US

    Uploaded by

    Danesh Jemy Ann Sapero

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    GUID - 1 en-US

    Uploaded by

    Danesh Jemy Ann Sapero
    5 views1 page

    Original Title

    GUID-D667E341-63E0-40F5-B08A-16D6A51EE625_1_en-US (1)

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    5 views1 page

    GUID - 1 en-US

    Uploaded by

    Danesh Jemy Ann Sapero

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    You are on page 1of 1

    Printed on: Sun Feb 04 2024, 08:08:20 PM(EST) Status: Currently Official on 05-Feb-2024 DocId: GUID-D667E341-63E0-40F5-B08A-16D6A51EE625_1_en-US

    Printed by: uspnf ustlibrary63 Official Date: Official Prior to 2013 Document Type: USP @2024 USPC
    Do Not Distribute DOI Ref: ht447 DOI: https://doi.org/10.31003/USPNF_M35460_01_01
    1

    B: Disperse 12 Suppositories in about 125 mL of water in a


    Glycerin Suppositories 250-mL beaker on a hot plate. Cool, add 1.5 mL of
    hydrochloric acid, and pour the mixture into a 250-mL
    » Glycerin Suppositories contain Glycerin solidified separator. Extract with 75 mL of hexanes, discarding the lower
    aqueous layer and collecting the organic layer in a beaker.
    with Sodium Stearate. [NOTE—If preferred, the Evaporate with the aid of a steam bath to near dryness: the IR
    Sodium Stearate for Glycerin Suppositories may be absorption spectrum of a mineral oil dispersion of the residue
    prepared during the making of the Suppositories so obtained exhibits maxima only at the same wavelengths as
    by the direct reaction between Stearic Acid and those of a mineral oil dispersion of USP Stearic Acid RS.
    Sodium Bicarbonate, Sodium Carbonate, or Water Determination, Method I á921ñ: not more than
    15.0%.
    Sodium Hydroxide, these being taken in the Assay—Transfer an accurately weighed quantity of
    correct proportion.] Glycerin Suppositories contain Suppositories, equivalent to about 250 mg of glycerin, to a
    not less than 75.0 percent and not more than 90.0 250-mL volumetric flask. Dissolve in water, dilute with water
    percent, by weight, of glycerin (C3H8O3). to volume, and mix. Pipet 5 mL of this solution into a 250-mL
    conical flask, and add 50.0 mL of a reagent prepared by mixing
    Packaging and storage—Preserve in well-closed 40 mL of dilute sulfuric acid (1 in 20) with 60 mL of potassium
    containers. periodate solution (1 in 1000) acidified with 3 to 5 drops of
    USP Reference standards á11ñ— sulfuric acid. Heat the solution on a steam bath for 15 minutes,
    USP Stearic Acid RS cool to room temperature, and add 1 g of potassium iodide.
    Allow the flask to stand for 5 minutes, and titrate with 0.02 N
    Identification— sodium thiosulfate VS, adding 3 mL of starch TS as the
    A: Dissolve 1 g of sodium borate in 100 mL of water, add endpoint is approached. Perform a blank determination, using

    al
    25 drops of phenolphthalein TS, and mix. To a test tube water in place of Suppositories, and note the difference in
    containing 0.5 mL of this solution add 2 drops of 1 Suppository volumes required. Each mL of the difference in volume of
    that has been melted: the pink solution becomes colorless, and 0.02 N sodium thiosulfate consumed is equivalent to
    when it is heated the pink color reappears. ci 0.4604 mg of glycerin (C3H8O3).
    ffi
    O

    https://online.uspnf.com/uspnf/document/1_GUID-D667E341-63E0-40F5-B08A-16D6A51EE625_1_en-US 1/1

    You might also like