Simhadri Praveen

simha9848@gmail.com
9618632850

Kumar
Hyderabad, Telangana 500043
WWW:
https://www.linkedin.com
/in/simhadri-praveen-kumar-
96260b3a/

Skills Summary
• Faculty Collaboration To pursue a research career in the biological based industry in a that can provide
• Performing molecular me the opportunity to grow professionally and personally.
experiments
• Drafting manuscripts after
Experience
reviewing experimental data
• Performing histology Malla Reddy University - Assistant Professor In Department Of Biotechnology
experiments Hyderabad
• Drafting IACUC guidelines 11/2022
• Implementing GLP procedures in • Provided instruction and guidance to undergraduate and graduate students in
the lab the classroom setting.
• Technology Implementation • Developed and implemented innovative teaching methods that enhanced
• Student Counseling student engagement and learning outcomes.
• Interdisciplinary Collaboration • Collaborated with colleagues on curriculum development initiatives to ensure
• Lesson Planning academic excellence.
• Meeting participation • Assisted in developing departmental policies, procedures, and activities related
to educational programs.
Education And Training
University At Buffalo - Post-Doctoral Fellow
12/2019 Buffalo, New York, United States
PhD: 10/2021 - 09/2022
Biotechnology
University Of Hyderabad • Studied molecular signaling Brain Angiogenic Inhibitor-1 and Minute Double
Hyderabad, Telangana Minute 2 pathways of addiction in brain regions of cocaine self-administered
animals
04/2011 • Analyzed data collected from experiments and prepared reports of findings.
MSc: • Discussed research summaries with project team to monitor progress.
Biotechnology • Performed trend analysis data of drug dosage of substances in animals and
Gandhi Institute Of Technology evaluated the addictive levels
And Management University • Trained Masters students with molecular biology experiments
Visakahapatnam
Indian Immunologicals Limited - Quality Control Analyst
04/2009 Hyderabad, India
BSc: 01/2011 - 01/2013
Biotechnology
Andhra University • Served as a quality control analyst in the department of microbiology for
Visakhapatnam manufacturing animal vaccines at Indian Immunologicals Limited, Hyderabad,
Division of National Dairy Development Board
• Developed and implemented procedures for inspecting, testing and evaluating
the precision and accuracy of raw materials and animal vaccines.
• Performed root cause analysis on non-conforming materials to identify problems
and corrective action plans.
• Involved in audits of internal systems, processes, products and services in order
to assess their effectiveness.
• Analyzed statistical data from inspections and tests in order to recommend
changes in process controls or design modifications that will improve product
reliability.
• Calibrated, validated or maintained laboratory equipment.
• Interpreted test results, compared to specifications and control limits and
recommended data for release.
• Conducted routine and non-routine analyses of in-process materials or stability
samples.

Fellowships And Awards

• Received Gold medal for 1st rank and University fellowship during Masters in
GITAM University 2011
• Department of Science and Technology (DST- INSPIRE) fellowship 2013-2018
• Department of Biotechnology (DBT)-CTEP travel grant 2017
• Received Gold Medal for Young Scientist Award from Association of
Biotechnology and Pharmacy 2017
• Summer Research Fellow (Indian National Science Academy) 2010

Publications
• Kumar SP, Babu PP. NADPH Oxidase: a Possible Therapeutic Target for Cognitive
Impairment in Experimental Cerebral Malaria. Mol Neurobiol 2022 Feb
59(2):800-820. doi:10.1007/s12035-021-02598-1
• Kumar SP, Babu PP. Aberrant Dopamine Receptor Signaling Plays Critical Role in
the Impairment of Striatal Neurons in Experimental Cerebral Malaria. Mol
Neurobiol 2020. doi:10.1007/s12035-020-02076-0
• Simhadri PK, Malwade R, Vanka R, Nakka VP, Kuppusamy G, Babu PP.
Dysregulation of LIMK-1/cofilin-1 pathway: A possible basis for alteration of
neuronal morphology in experimental cerebral malaria. Ann Neurol. 2017
Sep;82(3):429-443. doi: 10.1002/ana.25028.
• Vanka R, Nakka VP, Kumar SP, Baruah UK, Babu PP. Molecular targets in cerebral
malaria for developing novel therapeutic strategies. Brain Res Bull. 2020 Apr;
157:100-107. doi:10.1016/j.brainresbull.2020.01.
• Nakka VP, Raghu G, Simhadri PK, Mohammed AQ, Babu PP. Post-treatment with
apocynin at a lower dose regulates the UPR branch of eIF2α and XBP-1 pathways
after stroke. Brain Res Bull. 2022 May;182:1-11. doi:
10.1016/j.brainresbull.2022.02.003.
• Narne P, Pandey V, Simhadri PK, Phanithi PB. Poly(ADP-ribose)polymerase-1
hyperactivation in neurodegenerative diseases: The death knell tolls for neurons.
Semin Cell Dev Biol. 2017 Mar;63:154-166. doi: 10.1016/j.semcdb.2016.11.007.
• Vanka R, Kuppusamy G, Praveen Kumar S, Baruah UK, Karri VVSR, Pandey V, Babu
PP. Ameliorating the in vivo antimalarial efficacy of artemether using
nanostructured lipid carriers. J Microencapsul. 2018 Mar;35(2):121-136. doi:
10.1080/02652048.2018.1441915.
• Baruah UK, Gowthamarajan K, Ravisankar V, Karri VVSR, Simhadri PK, Singh V,
Babu PP.Design, characterization and antimalarial efficacy of PEGylated
galactosylated nano lipid carriers of primaquine phosphate. Artif Cells Nanomed
Biotechnol. 2018 Dec;46(8):1809-1829. doi: 10.1080/21691401.2017.1394870.
• Baruah UK, Gowthamarajan K, Ravisankar V, Karri VVSR, Simhadri PK, Singh V.
Optimisation of chloroquine phosphate loaded nanostructured lipid carriers
using Box-Behnken design and its antimalarial efficacy. J Drug Target. 2018
Aug;26(7):576-591. doi: 10.1080/1061186X.2017.1390671.

Doctoral Research Experience

Title of my Thesis- "Cognitive dysfunction in experimental cerebral malaria:
Possible role of neurodegeneration and morphological alterations " awarded under
the supervision of Prof.P.Prakash Babu at the University of Hyderabad, Telangana
on December 2019.

Training
• Attended International Brain Research Organization (IBRO)-Associate School of
Neuroscience on 'Recent Advances in Tools and Techniques in Neuroscience
Research' held on 26-31 March, 2018 at Savitribai Phule University, Pune and
presented a seminar on 'Aberrant activity of CDK5, hyperdopamine tone alters
D1R/PKA/DARPP-32/PP1 pathway; a possible basis for dysregulation of NR2B,
AMPA receptors and CaMKII proteins in experimental cerebral malaria.'
• Attended IBRO- Asia Pacific Regional Committee (APRC) School of Neuroscience -
Epigenetic regulation of neuronal gene expression held on April 1-16, 2017 at
Banaras Hindu University, Varanasi and presented a seminar on 'Altered neuronal
morphology and dysregulation of LIMK-1/Cofilin-1 pathway in experimental
cerebral malaria.'

Accomplishments
• Received Gold medal for 1st rank and University fellowship during Masters in
GITAM University 2011
• Received Department of Science and Technology (DST- INSPIRE) fellowship
2013-2018 (DST/INSPIRE Fellowship/2013/710)
• Received travel grant from the Department of Biotechnology (DBT)-CTEP travel
grant 2017 (DBT/CTEP/02/201700810) to XX!V attend World Congress of
Neurology, Japan
• Received Gold Medal for Young Scientist Award from Association of
Biotechnology and Pharmacy in 2017
• Worked as a Summer Research Fellow (Indian National Science Academy) 2010
under the supervision of Dr. Amulya Kumar Panda, staff scientist, National
Institute of Immunology, New Delhi, INDIA

References
• Prof.P.Prakash Babu, Biotechnology and Bioinformatics, University of Hyderabad,
Hyderabad, Telangana, 500046, prakash@uohyd.ac.in, 9441583525
• Prof. N.Venkata Prasuja, Biochemistry, Acharya Nagarjuna University, Guntur,
Andhra Pradesh, 522510, India, nvprasuja@gmail.com, 9949913760
• Prof. David Dietz, Pharmacology and Toxicology, Jacobs School of Medicine and
Biomedical Sciences, University of Buffalo, Buffalo, NY, 14203,
ddietz@buffalo.edu, +18507661387