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Paper / Subject Code: 87612 / Pharmacology- III

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B1
21

6A
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3C

C0

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28

AA
0A

A6

B1
4C
21
53

6
C
AA

0
F
28

CC
3

A
FD

21

A
30

AA

F4
61

6
C
Duration : 3 hours Total Marks : 75

D5

8
A0

AA
0A

12
A6

4C
F

2
89

61

53

86
3C
AA

AF
17
Q. I Choose the ONE best answer and write it down 20 M

FD

12
A

A6

6A
0
0B

2
9

61

3C
8

AA
D5
Sr

28
CC

17

A0

21
1F
No Questions Options

30
B

AA
F4

9
0

C
8

06

D5

8
1 Ipratropium is used in treatment of asthma for which of a Beta 2 antagonistic

C
AA

3
0A

12
B1
4C

6
1F
the following action?

AA

C2
9
86

53
0
F

78

06
CC
A
b Beta 2 agonistic
12

3
FD

A
B1

6
A

30
C2

AA
F4

9
6
c Anticholinergic

61
C0

8
8

D5
63

AA

17
12

0A
d Anti-tussive

4C

1F
AA

0B
2

A
89
6

53
C

AF

AA
8

6
CC
3

17
0A

12

FD
A6

2 A drug used in treatment of COPD which increases a Corticosteroids

9A
A

30
0B
2

F4
3

61
3C
AA

mucociliary clearance is:

D5

78
28

D5
C
A

A0
6

B1
4C
21

A
1F

b Tacrolimus
30

1F
AA

89
86
C

0
F
06

D5

c Theophylline

06
CC
3

AA

17
0A

12
9A

9A
1F

d Methotrexate
A

B
C2

F4
53

6
78

0
06

78
28

CC
3 Which nasal decongestant is commonly used and has a Ephedrine 3

AA
FD

A
B1

9A

B1
21
30

A
long duration of action?

F4
61

86
C0

3C
78

C0
D5
A0

A
0A

b Epinephrine

2
B1
4C

4C
1

A
1F

AA

2
9

c Oxymetazoline

6
C0
AF

3C
78

AF
6

D5

28
0

d Propylhexedrine
B1
4C

9A

A6
6A

21

6A
F

30
61
C0
AF

3C
4 A drug which can be used for liquification of viscid a Methotrexate
78

AA
28

28
A0

FD
B1
4C
21

6
6A

sputum is:

21
30

AA
89

1
3C

C0
AF

3C
28

06

b Ephedrine
D5
17

A
A6

4C
21

A6
6A

1F

c Carbocisteine
0
B

53
3C
AA

0
AF

AA
28

d Tacrolimus
C

A0

FD
A6

B1
C
21

6A
30

30

5 The fixed dose combination of trimethoprim and a Cotrimoxazole

F4

61
3C
AA

C0
D5

8
28

D5
A

sulfamethoxazole is called:
7

A0
A6

1
4C
21

A
30

1F
0B

b Sulfonamide
89
86
3C
AA

AF
D5

06
C

17
2

c Quinolone
A6

4C
21

9A
A
1F

30

B
6

d Penicillin
3C
AA

0
AF
06

D5

78
8

CC
2
9A

A6

B1

6 Which of the following antibiotics acts by inhibiting a Chloramphenicol

21

6A
1F

30

F4
C

bacterial protein synthesis by interfering with ‘transfer’

78

AA

C0
06

8
3

AA
FD

2
9A

A6

4C
1

of the elongating peptide chain to the newly attached

30

C2
61

86
78

AA

AF
D5

aminoacyl-tRNA?
A0

12
B1

A6

6A
1F

30

b Clindamycin
C2
89
C0

AA
06

D5

28
17

63

c Tetracyclines
4C

9A

21
1F

30
0B

AA

d Aminoglycosides
3C
78

06

D5
CC

0A
B1

9A

A6
1F
F4

53

7 Vestibular ototoxicity is an adverse effect of: a Aminoglycosides

C0

78

AA
06
AA

D
B1
4C

9A

b Quinolones
F

30
86

61
C0
AF

78

D5

c Tetracycline
12

A0
B1
4C
6A

1F

d Sulphonamides
89
C0
AF
28

06
7
B1
4C
21

9A
6A
3C

C0
AF

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Paper / Subject Code: 87612 / Pharmacology- III

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63

B1
21

6A
AA

F4

9
3C

C0

78
28

AA
0A

A6

B1
4C
21
53

6
C
AA

0
F
28

CC
3

A
FD

21

A
30

AA

F4
61

6
C
D5
8 Beta-lactam antibiotics inhibit which of the following to a Transpeptidases

8
A0

AA
0A

12
A6

4C
F
prevent cross linking ?

2
89

61

53

86
3C
AA

AF
17

FD

12
A

A6

6A
0
0B
b mRNA reading

2
9

61

3C
8

AA
D5

28
CC

17

A0
c Phosphorylation

21
1F

30
B

AA
F4

9
d Protein synthesis

C
8

06

D5

8
C
AA

3
0A

12
9 Which of the following drugs can cause cinchonism? a Artenisinin

B1
4C

6
1F

AA

C2
9
86

53
0
F

78

06
CC
A
12

3
FD

A
b Quinine

B1

6
A

30
C2

AA
F4

9
6

61
C0
c Primaquine

8
8

D5
63

AA

17
12

0A
4C

A
d Atropine

1F
AA

0B
2

A
89
6

53
C

AF

AA
8

6
CC
10 Levamisole is a nicotinic receptor agonist used as an: a Antimalarial
3

17
0A

12

FD
A6

9A
A

30
0B
2

F4
3

61
3C
AA
D5

78
28

D5
C
A
b Anthelmintic

A0
6

B1
4C
21

A
1F

30

1F
AA

89
86
c Antitubercular C

0
F
06

D5

06
CC
3

AA

17
0A

12
9A

6
d Antiamoebic

9A
1F

B
C2

F4
53

6
78

0
06

11 Which of the following azole antifungals is used only a Ketoconazole

78
28

CC
3

AA
FD

A
B1

9A

B1
21
topically?
30

F4
61

86
C0

3C
78

C0
D5

b Econazole
A0

A
0A

2
B1
4C

4C
1

A
1F

AA
c Fluconazole

2
9

6
C0
AF

3C
78

AF
6

D5

28
0

d Itraconazole
B1
4C

9A

A6
6A

21

6A
F

30
61

12 Diloxanide furoate is classified as an: a Anthelmintic

C0
AF

3C
78

AA
28

28
A0

FD
B1
4C

b Amoebicide
21

6
6A

21
30

AA
89

1
3C

C0
AF

3C
28

c Antifungal
06

D5
17

A
A6

4C
21

A6
6A

1F

d Antiviral
0
B

53
3C
AA

0
AF

AA
28

6
C

13 Which of the following is a microtubule damaging agent? a Letrozole

7

A0

FD
A6

B1
C
21

6A
30

30
F4

b Tamoxifen
9

61
3C
AA

C0
D5

8
28

D5
A

A0
A6

1
4C
21

A
30

1F

c Methotrexate
0B

89
86
3C
AA

AF
D5

06
C

d Vinblastine
17
2
A6

4C
21

9A
A
1F

30

14 Infliximab is classified as: a Anti CD-3 antibody

6
3C
AA

0
AF
06

D5

78
8

CC
2
9A

A6

B1
21

6A
1F

30

F4
C
78

AA

C0
06

b IL-1 receptor antagonist

5

8
3

AA
FD

2
9A

A6

4C
1
30

c IL-2 receptor antagonist

C2
61

86
78

AA

AF
D5

d TNFα inhibitor
A0

12
B1

A6

6A
1F

30

C2

15 Cyclosporine acts on: a CD3 Cells

89
C0

AA
06

D5

28
17

63

b CD8 Cells
4C

9A

21
1F

30
0B

AA

c B Lymphocytes
3C
78

06

D5
CC

0A
B1

d CD4 Cells
9A

A6
1F
F4

53
C0

78

AA
06
AA

D
B1
4C

9A

30
86

61
C0
AF

78

D5
12

A0
B1
4C
6A

1F
89
C0
AF
28

06
7
B1
4C
21

9A
6A
3C

C0
AF

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B1
21

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9
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C0

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AA
0A

A6

B1
4C
21
53

6
C
AA

0
F
28

CC
3

A
FD

6
16 Which of the following drug is used as anti-cancer agent a Atropine

21

A
30

AA

F4
61

6
C
as well as an immunosuppressant?

D5

8
A0

AA
0A

12
A6

4C
b Vincristine

2
89

61

53

86
3C
AA

AF
c Tetracycline

17

FD

12
A

A6

6A
0
0B
d Methotrexate

2
9

61

3C
8

AA
D5

28
CC

17

A0
17 The Universal antidote is: a Activated charcoal

21
1F

30
B

AA
F4

9
0

C
8

06

D5
b BAL

8
C
AA

3
0A

12
B1
4C

6
1F

AA

C2
9
86

53
0
F
c Dimercaprol

78

06
CC
A
12

3
FD

A
B1

6
A

30
C2

AA
F4

9
6
d Lime

61
C0

8
8

D5
63

AA

17
12

0A
18 Which of the following is a characteristic of acute a Sudden in onset

4C

1F
AA

0B
2

A
89
6

53
C
toxicity?

AF

AA
8

6
CC
3

17
0A

12

FD
A6

9A
A

30
0B
2

F4
3

b Persistent over months

61
3C
AA
D5

78
28

D5
C
A

A0
c Slowly changing
6

B1
4C
21

A
1F

30

1F
AA

89
86
C

0
F
d Slowly occurring
06

D5

06
CC
3

AA

17
0A

12
9A

9A
19 Circadian rhythms are physical, mental, and behavioural a 24-hour cycle.
1F

B
C2

F4
53

6
78

0
06

78
28
changes that follow a:

CC
3

AA
FD

A
B1

9A

B1
21
30

b 4-hour cycle.
A

F4
61

86
C0

3C
78

C0
D5

c 12-hour cycle.
A0

A
0A

2
B1
4C

4C
1

A
1F

AA

2
9

d 6-hour cycle.
3

6
C0
AF

3C
78

AF
6

D5

28
0

A
B1
4C

9A

A6
6A

21

6A
F

20 The circadian rhythm is controlled by a group of cells in a Hypothalamus

30
61
C0
AF

3C
78

AA
28

28
the:
A0

FD
B1
4C
21

6
6A

21
30

AA
89

1
3C

C0
AF

3C
28

06

D5
17

A
A6

b Central Nervous System

4C
21

A6
6A

1F

0
B

53
3C
AA

0
AF

c Brain Stem
8

AA
28

6
C

A0

FD
A6

B1
C
21

6A

d Pituitary Gland
30

30
F4

61
3C
AA

C0
D5

8
28

D5
A

A0
A6

1
4C
21

A
30

1F
0B

89
86
3C
AA

AF
D5

06
C

17
2
A6

4C
21

9A
A
1F

30

Q. II Answer Any Two from the following: 20 M

B
6
3C
AA

0
AF
06

D5

78
8

CC
2
9A

A6

B1
21

1. Classify drugs used for the treatment of asthma with examples. Give mechanism of action
6A
1F

30

F4
C
78

AA

C0
06

and ADR of any two classes.

3

AA
FD

2
9A

A6

4C
1
30

C2
61

86
78

AA

AF

2. Classify anti-microbials based on their mechanism of action. Elaborate on mechanism of

D5
A0

12
B1

A6

6A
1F

microbial resistance. Write a note on rational use of antibiotics.

30

C2
89
C0

AA
06

D5

28
17

63
4C

9A

21
1F

30
0B

3. Classify anti-malarial drugs with example. Illustrate targets of antimalarial drugs.

AA

3C
78

06

D5
CC

Elaborate on mechanism of action, adverse effects, and uses of 4-amino quinolone drugs.
0A
B1

9A

A6
1F
F4

53
C0

78

AA
06
AA

D
B1
4C

9A

30
86

61
C0
AF

78

D5
12

A0
B1
4C
6A

1F
89
C0
AF
28

06
7
B1
4C
21

9A
6A
3C

C0
AF

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B1
21

6A
AA

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3C

C0

78
28

AA
0A

A6

B1
4C
21
53

6
C
AA

0
F
28

CC
3

A
FD

21

A
30

AA

F4
61

6
C
D5

8
A0

AA
0A

12
A6

4C
F

2
89

61

53

86
3C
AA

AF
Q. III Answer Any Seven from the following. 35 M

17

FD

12
A

A6

6A
0
0B

2
9

61

3
1. Write a short note on Nasal decongestants.

3C
8

AA
D5

28
CC

17

A0

21
1F

30
B

AA
F4

9
0
2. Classify Drugs used in treatment of peptic ulcer. Give mechanism of action and adverse

C
8

06

D5

8
C
AA

3
0A

12
B1
4C

6
effects of Sucralfate.

1F

AA

C2
9
86

53
0
F

78

06
CC
A
12

3
FD

A
B1
3. Classify fluoroquinolones. Describe their mechanism of action, therapeutic uses, and general

6
A

30
C2

AA
F4

9
6

61
C0
adverse effects.

8
8

D5
63

AA

17
12

0A
4C

1F
AA

0B
2

A
89
6

53
C

AF

AA
8

6
4. Classify anti-retroviral drugs. Describe the mechanism of action, therapeutic uses, and adverse

CC
3

17
0A

12

FD
A6

9A
A
effects of nucleoside reverse transcriptase inhibitors (NRTIs).

30
0B
2

F4
3

61
3C
AA
D5

78
28

D5
C
A

A0
6

B1
4C
21

A
1F

30

1F
AA

5. Enlist the drugs used in leprosy and give a detailed account on Dapsone

89
86
C

0
F
06

D5

06
CC
3

AA

17
0A

12
9A

9A
1F

B
C2

F4
6. Classify anticancer drugs. Write a note on vinca alkaloids.
53

6
78

0
06

78
28

CC
3

AA
FD

A
B1

9A

B1
21
30

F4
61

86
C0

3C
7. Enlist disorders in which immune-suppressants are prescribed Write a note on interferons.
78

C0
D5
A0

A
0A

2
B1
4C

4C
1

A
1F

AA

2
9

8. Give details on the management of arsenic poisoning.

6
C0
AF

3C
78

AF
6

D5

28
0

A
B1
4C

9A

A6
6A

21

6A
F

30

9. What is chronotherapy? Discuss about chronotherapy for diabetes mellitus

61
C0
AF

3C
78

AA
28

28
A0

FD
B1
4C
21

6
6A

21
30

AA
89

1
3C

C0
AF

3C
28

06

D5
17

A
A6

4C
21

A6
6A

1F

0
B

53
3C
AA

0
AF

AA
28

6
C

A0

FD
A6

B1
C
21

6A
30

30

**************
F4

61
3C
AA

C0
D5

8
28

D5
A

A0
A6

1
4C
21

A
30

1F
0B

89
86
3C
AA

AF
D5

06
C

17
2
A6

4C
21

9A
A
1F

30

B
6
3C
AA

0
AF
06

D5

78
8

CC
2
9A

A6

B1
21

6A
1F

30

F4
C
78

AA

C0
06

8
3

AA
FD

2
9A

A6

4C
1
30

C2
61

86
78

AA

AF
D5
A0

12
B1

A6

6A
1F

30

C2
89
C0

AA
06

D5

28
17

63
4C

9A

21
1F

30
0B

AA

3C
78

06

D5
CC

0A
B1

9A

A6
1F
F4

53
C0

78

AA
06
AA

D
B1
4C

9A

30
86

61
C0
AF

78

D5
12

A0
B1
4C
6A

1F
89
C0
AF
28

06
7
B1
4C
21

9A
6A
3C

C0
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