Finance Project Proposal

PROJECT PROPOSAL
4CSPL2041 – INTRODUCTION TO MACHINE LEARNING
PROJE
CARDIO VASCULAR DISEASE PREDICTION USING MACHINE LEARNING
CT
TITLE
DOMAIN HEALTH CARE
OR FIELD
TEAM
SHAISTA FATHIMA M (21BBTCS213) ,
MEMBE
RS SUPRIYA PARASAPPA JALAGERI (21BBTCS235)
SUBMISSI Faculty In charge Signature

ON DATE 06/04/2024 APPROVED Prof. Shivakumar
BY: - Shriya
I. Cardiovascular diseases (CVDs) are a group of disorders affecting the heart and blood
INTRODUCTI vessels, and are a leading cause of mortality and morbidity worldwide. Understanding the
ON TO factors that contribute to the development and progression of CVDs is crucial in order to
DOMAIN AND develop effective prevention and treatment strategies. In this proposal, we aim to explore
PROBLEM the use of machine learning techniques to predict the occurrence of cardiovascular disease
IDENTIFIED events, with the goal of improving early detection and intervention. Event prediction has
been the cornerstone of cardiovascular epidemiology as exemplified by the Framingham
study and other prospective studies that function as pillars for much of what comprises
current cardiovascular medicine. A fundamental goal of such efforts has been event
prediction over relatively long periods of time such as 10 years or a lifetime. These efforts
have allowed us to characterize subclinical disease processes and target key risk factors
for modification (eg, smoking cessation, statin therapy, blood pressure control).
Epidemiological studies used to derive such predictive models frequently contain
hundreds or thousands of variables. It is in this context that machine learning methods
might be useful as a means to identify the best predictors of outcomes from among
millions of phenotypic data points.
Predicting the risk of cardiovascular disease events is a complex challenge, as it involves

the interplay of various demographic, clinical, and lifestyle factors. Traditional risk
assessment models have relied on statistical methods, but advancements in machine
learning have opened up new avenues for more accurate and personalized risk prediction.
By leveraging large-scale data and sophisticated algorithms, we can uncover hidden
patterns and relationships that may not be readily apparent using conventional approaches.
Regression analysis is a pivotal tool in cardiovascular disease (CVD) events prediction,

serving to uncover and quantify the relationships between various risk factors and the
likelihood of experiencing a CVD event, such as heart attacks or strokes. By analyzing
historical data, regression models enable healthcare professionals to predict future CVD
events for individual patients or populations, facilitating early intervention and tailored
preventive measures.
II. BACKGROUND Cardiovascular diseases (CVDs) are a group of disorders affecting the heart and blood
vessels, including conditions such as coronary heart disease, stroke, and heart failure.
These diseases are a leading cause of mortality and morbidity worldwide, responsible for
an estimated 17.9 million deaths globally in 2019. Understanding the risk factors and
developing accurate predictive models for CVD events is essential for early intervention,
prevention, and improved patient outcomes.
Cardiovascular disease (CVD) events prediction has been a critical area of research and
clinical practice for decades due to the significant impact of CVD on public health
worldwide. CVD encompasses various conditions affecting the heart and blood vessels,
including coronary artery disease, heart failure, stroke, and peripheral artery disease.
These conditions are leading causes of morbidity and mortality globally, contributing to a
substantial burden on healthcare systems and economies.
Several studies have identified various demographic, lifestyle, and clinical factors
associated with an increased risk of CVD, including age, gender, family history,
hypertension, diabetes, dyslipidemia, obesity, smoking, and physical inactivity.
III. OBJECTIVES 1. To develop a robust and accurate predictive model that can forecast the likelihood
of cardiovascular disease events, such as heart attacks and strokes, based on patient
data.
2. To identify the key risk factors and variables that have the most significant impact
on the development of cardiovascular disease.
3. To ensure the robustness and generalizability of the models, a cross-validation

approach will be employed.
4. This involves splitting the dataset into multiple folds, training the models on a
subset of the data and evaluating them on the remaining unseen data.
5. To create a user-friendly tool or dashboard that can be easily integrated into

clinical workflows, allowing healthcare professionals to quickly assess a patient's
risk .
6. To enhance the understanding of the complex relationships between various

demographic, lifestyle, and clinical factors that contribute to cardiovascular
disease, providing valuable insights for future research and public health
initiatives.
IV.
METHODOLOGY  Data Collection: Collecting high-quality, comprehensive data is crucial for
building an effective machine learning model to predict cardiovascular disease
events. The first step in this process is identifying relevant data sources that can
provide the necessary information to train and validate the model.
 Data Preprocessing: Effective data preprocessing is a critical step in building

accurate machine learning models for cardiovascular disease prediction. The raw
data collected from various sources often contains noise, missing values, and
irrelevant features that can negatively impact the model's performance.
 Model Selection: The first step in the model selection process is to identify the
most appropriate machine learning algorithms for the task of cardiovascular
disease event prediction. Based on the nature of the problem and the available
data, we will consider a range of supervised learning models, including logistic
regression, decision trees, random forests, and gradient boosting algorithm.
 Model Development: Model development for cardiovascular disease (CVD)

events prediction involves a systematic approach to constructing robust
algorithms that accurately estimate the likelihood of individuals experiencing
CVD-related events. Beginning with comprehensive data collection
encompassing demographic details, medical history, physiological measures,
lifestyle factors, and genetic predispositions, the data undergoes meticulous
preprocessing to handle missing values and standardize features.
V. REFERENCES
 Lloyd-Jones DM. Cardiovascular risk prediction: basic concepts, current status,

and future directions Circulation:2010
 Goff DC, Lloyd-Jones DM, Bennett G, et al; American College of

Cardiology/American Heart Association Task Force on Practice Guidelines. 2013
ACC/AHA guideline on the assessment of cardiovascular risk: a report of the
American College of Cardiology/American Heart Association Task Force on
Practice Guidelines.J Am Coll Cardiol 2014.
 Deo RC. Machine learning in medicine.Circulation 2015.
 Lloyd-Jones DM, Wilson PW, Larson MG, Beiser A, Leip EP, D’Agostino RB,
Levy D. Framingham risk score and prediction of lifetime risk for coronary heart
disease.Am J Cardiol. 2004
 Cox DR. Regression models and life-tables.J R Stat Soc Series B. 1972
 Sitar-tăut A, Zdrenghea D, Pop D, Sitar-tăut D. Using machine learning algorithms

in cardiovascular disease risk evaluation.Age. 2009.

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PROJECT PROPOSAL

4CSPL2041 – INTRODUCTION TO MACHINE LEARNING

SUBMISSI Faculty In charge Signature

Predicting the risk of cardiovascular disease events is a complex challenge, as it involves

Regression analysis is a pivotal tool in cardiovascular disease (CVD) events prediction,

3. To ensure the robustness and generalizability of the models, a cross-validation

5. To create a user-friendly tool or dashboard that can be easily integrated into

6. To enhance the understanding of the complex relationships between various

 Data Preprocessing: Effective data preprocessing is a critical step in building

 Model Development: Model development for cardiovascular disease (CVD)

 Lloyd-Jones DM. Cardiovascular risk prediction: basic concepts, current status,

 Goff DC, Lloyd-Jones DM, Bennett G, et al; American College of

 Deo RC. Machine learning in medicine.Circulation 2015.

 Sitar-tăut A, Zdrenghea D, Pop D, Sitar-tăut D. Using machine learning algorithms

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