Updated CV Crystal Yeo Aug 2021
Updated CV Crystal Yeo Aug 2021
Updated CV Crystal Yeo Aug 2021
Board Cert
(Neurology, Neuromuscular Medicine), A.B.E.M. Board Cert (Electrodiagnostic
Medicine)
Personal Particulars
Email address crystaljjyeo@cantab.net
Twitter @crystalyeomdphd
Academic Qualifications
Diplomate of American Board of Psychiatry and Neurology
Board Certification in Neuromuscular Medicine – 10/2020
Board Certification in Neurology – 09/2018
Diplomate of American Board of Electrodiagnostic Medicine
Board Certification in Electrodiagnostic Medicine – 03/2020
Neuromuscular Medicine Fellowship
Brigham and Women’s Hospital, Massachusetts General Hospital, Boston Children’s Hospital, Harvard University
Neuromuscular Medicine Fellowship – 07/2018 to 06/2019
Neurology Residency
Houston Methodist Hospital, Texas Medical Centre
Neurology Residency 07/2014 – 06/2018
Graduate
University of Cambridge, Cambridge, United Kingdom
Immunology, Medicine 10/2006 - 07/2009
PhD, 04/2010
Undergraduate
University of Cambridge, Cambridge, United Kingdom
MB-PhD Program
Medicine 08/2005 - 08/2011
MB BChir Distinction, 06/2011
Professional Exams
American Board of Psychiatry and Neurology (ABPN) Neuromuscular Board Certification Exam 2020
Score 91.5% (Passing score 66.3%)
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM) Neuromuscular Exam 2019
Rank 1st among all exam takers, Score 139 out of 147
American Board of Psychiatry and Neurology (ABPN) Neurology Board Certification Exam 2018
Score 437 (Passing score 247, Mean score of all exam takers 306)
USMLE 2015
Step 3 score 248
Internal Medicine In-Training-Exam 2014
Score 83%, percentile 99% for PGY-1 and percentile 98% for PGY-4 for all examinees
USMLES 2013
Step 1 score 268
Step 2 score 275
Step 2 CS score pass
MRCP UK 2013
Part 1 Written score 738/999
Part 2 Written score 741/999
Professional Accreditations
Advanced Cardiovascular Life Support - American Heart Association accredited 05/2018
Fundamental Critical Care Support Course-United States accredited 03/2012
Educational and Hands-on Training BOTOX for Upper Limb Spasticity, Lower Limb Spasticity and Cervical
Dystonia 09/2017
Leadership Experience
06/2021
Chair of the discussion panel for the ASEAN-ROK Science, Technology, and Innovation Workshop
05/2021
American Academy of Neurology (AAN) Pipeline Subcommittee
05/2021
Facilitator for Conversation on Singapore Women’s Development in Healthcare
12/2020 to present
National Conversation on Women’s Development, Ministry of Culture, Community and Youth
12/2019 – 05/2020
A*STAR First Managerial Development Program
11/2019 – 11/2019
Singapore delegate to ASEAN-Republic of Korea Program for Policy to increase R&D and Technology Transfers
05/2019 – Present
AAN Live Well Lead Well Leadership Program
05/2018 – Present
Palatucci Advocacy Leadership Forum Advocate
09/2017 – 08/2018
Muscle and Nerve Journal Editorial Board
10/2017 – present
Harris County Medical Society
Harris County Alternate Delegate to the TMA House of Delegates
08/2016 – 09/2019
American Association of Neuromuscular and Electrodiagnostic Medicine (AANEM)
Digital Media Education Committee
05/2016 – 06/2019
Texas Medical Association, TEXPAC Board of Directors
05/2016 – 06/2019
Texas Medical Association, Committee on Continuing Education
07/2015 – 06/2018
Houston Methodist Hospital
Graduate Medical Education Internal Review Committee
Graduate Medical Education Accreditation/Program Oversight GMEC Subcommittee
07/2015-07/2016
Houston Methodist Hospital
Crystal Jing Jing Yeo Page 4
Graduate Medical Education Committee (GMEC) representative (Alternate) for Neurology
Research Experience
08/2019 – present
Institute of Molecular and Cell Biology
Group Leader of the Translational Neuromuscular Medicine Laboratory which investigates clinical biomarkers,
diagnostics, and therapeutics to improve the lives of patients with neuromuscular diseases. Awarded the A*STAR
CDA Grant.
12/2018 – present
American Academy of Neurology (AAN)
Working with Palatucci Advocacy Leadership Forum and AAN Live Well Lead Well Program to engage physician
wellness advocacy leaders and provide effective online resources for advocacy
Awarded the AAN Palatucci Advocacy Leadership Forum Action Plan Support Grant
07/2018 – present
Massachusetts General Hospital, Harvard University
Worked with Professor Kathryn Swoboda, Chair in Neurogenetics, to lead study on outcome measures for
nusinersen efficacy in adults with spinal muscular atrophy.
Study supported by CureSMA
07/2018 – present
Boston Children’s Hospital, Harvard University
Working with Professor Basil Darras, Chief of the Division of Clinical Neurology and Director of the Neuromuscular
Center and Spinal Muscular Atrophy Program, on the paradigm of spinal muscular atrophy being a whole-body
disease with implications for patients of different ages
07/2016 – 06/2018
Houston Medical Hospital, Weil Cornell Medical College
Worked with Professor Suzanne Powell, Vice-Chair for Education, to lead studies on mindfulness interventions for
trainee wellness and responses to Hurricane Harvey
07/2007 - 07/2007
57th Meeting of Nobel Laureates in Physiology, Germany
08/2006 - 05/2009
Wellcome Trust Immunology Unit, University of Cambridge, United Kingdom
Worked with Professor Douglas Fearon, Professor of Immunology, to study the role of the transcription factor T-
bet on effector CD8+ T cell differentiation and survival in vitro and in vivo
Reviewer
Reviewer for Brain - July 2021 to date
Reviewer for Annals of Clinical and Translational Neurology - June 2021 to date
Reviewer for Neurology, Neurosurgery and Psychiatry – August 2020 to date
Reviewer for Neuromuscular disorders – August 2020 to date
Reviewer for European Journal of Neurology – May 2020 to date
Reviewer for RealEMG program for the AANEM – Feb 2019
Reviewer for single fiber EMG workshop for AANEM – Jan 2019
Reviewer for BMJ – 2018 to date
Reviewer for Muscle and Nerve – 2017 to date
Reviewer for the Journal of Neurology - 2015 to date
Reviewer for ultrasound teaching program mskNAV for the AANEM - Nov 2018
Yeo CJ, Ng SY, Darras BT. Reduced Spinal Motor Neuron Expression of Insulin-like Growth Factor-2 and Insulin-like
Growth Factor Binding Protein 5 in Spinal Muscular Atrophy Type 1. Accepted for Platform Presentation at the
American Academy of Neurology (AAN) Annual Meeting at Toronto in April 2020.
Yeo CJ, Schwartz H, Donovan C et al. Providing an easily accessible online resource for physician wellness
advocates. Accepted for Poster Presentation at the AAN Annual Meeting at Toronto in April 2020
Yeo CJ, Simeone S, Zhang RZ, Trautman K, Damron B, Nwe P, Siranosian J, Johnstone A, Chen JY, Townsend E, Nery
F, Herrmann M, Swoboda K. Outcome measures for Nusinersen efficacy in Adults with Spinal Muscular Atrophy.
Platform presentation at the American Academy of Neurology (AAN) Annual meeting in May 2019
Yeo CJ, Ng SY, Darras BT. Reduced Spinal Motor Neuron Expression of Insulin-like Growth Factor-2 and Insulin-like
Growth Factor Binding Protein 5 in Spinal Muscular Atrophy Type 1. Accepted for Platform Presentation at the
American Academy of Neurology (AAN) Annual Meeting at Toronto in April 2020.
Yeo CJ, Schwartz H, Donovan C et al. Providing an easily accessible online resource for physician wellness
advocates. Accepted for Poster Presentation at the AAN Annual Meeting at Toronto in April 2020
Yeo CJ, Babieri A, Roman G, Wiesman J, Powell SZ. Using Smartphone Mindfulness Apps to Increase Trainee
Resilience and Reduce Burnout. Presented at the AAN Annual meeting in May 2019
Yeo CJ, Ondo W. Tremor Research Group Essential Tremor Rating Scale (TETRAS): Assessing Impact of Different
Item Instructions. Presented at the AAN Annual Meeting 2018 in April 2018
Yeo CJ, Roman G, Kunerik D, Mersinger D, Thomas S, Burt T, Boone T, Powell SZ. Trainee Responses to Hurricane
Harvey: Correlating Volunteerism with Burnout. Presented at the ACGME Annual Meeting in March 2018 and AAN
in April 2018
Yeo CJ, Hutton GJ, Fung SH. Imaging in Balo’s Concentric Sclerosis: MRI, MRS, DTI, and ASL Perfusion Imaging.
Presented at the American Neurological Association Annual Meeting in Oct 2017.
Yeo CJ, Zhang JY, Powell SZ, Smith R, Britz G. Recurrent Cerebral Hemorrhage in Normal Pregnancy caused by
Mycotic Pseudoaneurysms and Choriocarcinoma. Presented at the American Neurological Association Annual
Meeting in Oct 2017.
Yeo CJ and Pleitez M. Eculizumab in Refractory Myasthenic Crisis. Presented at the AANEM Annual Meeting and
Myasthenia Gravis Foundation of America Annual Meeting in Sept 2017
Yeo CJ, Bunin V, Popovich J, Cykowski M, Smith R. Mitochondrial Skeletal and Cardiac Myopathy Responsive to
Aggressive Immunosuppression in Rapidly Progressing Systemic Sclerosis. Presented at the AAN Annual Meeting
in April 2017
Yeo CJ and Smith R. Oculomotor and Masticator Muscle Enhancement in a Case of Multiple Cranial Nerve Palsies
and Internuclear Ophthalmoplegia Associated with Herpes Simplex Virus Infection. Presented at the AANEM
Annual Meeting in Sept 2016
Yeo CJ, McCane D, Katz L, Ling K, Capetillo A, Bledsoe D, Chiu D. Variables affecting stroke outcome for t-PA
received between 3 to 4.5 hours. Presented at the AAN Annual Meeting in April 2016
Invited speaker on “Systemic Phenotypes and Innovative Therapies in Spinal Muscular Atrophy” at the US Women
Neurologists’ Group Feb 2021 CME Lecture
Invited speaker on “Presentations of Amyotrophic Lateral Sclerosis” at the Ochsner Neuroscience Grand Rounds
in August 2020
Invited speaker on “PEARLS for the General Neurologist: ALS and Mimics” at the Women Neurologists’ Group July
2020 CME Lecture
Invited speaker on “Diagnosis and Management of Amyotrophic Lateral Sclerosis” at St. Louis University School of
Medicine in June 2020
Invited speaker on “Creating Clinical Relevance from Research in Spinal Muscular Atrophy” at Neuroscience
Research Seminar at Imperial College London- Lee Kong Chien School of Medicine Singapore in November 2019
Grand Rounds speaker on “Precision Medicine: Gene and RNA therapies” at Houston Methodist Neurological
Institute in April 2018
Invited speaker and panelist on “Being a Resilient Leader: How Do You Lead the Change” at the 2018 AAN Annual
Meeting in April 2018
Invited speaker for “Neuromuscular Emergencies” at the 2017 Houston Methodist Annual Neuroscience Nursing
Conference in Oct 2017
Grand Rounds speaker on “How the Vagal Nerve Influences Inflammation” at Houston Methodist Neurological
Institute in March 2017
Podcast
ACGME podcast interview on my work presented at the 2018 ACGME Annual Meeting “Trainee Responses to
Hurricane Harvey: Correlating Volunteerism with Burnout” – broadcast date pending
Invited Interviews
ACGME website interview on my work which was presented at the 2018 ACGME Annual Meeting: “Trainee
Responses to Hurricane Harvey: Correlating Volunteerism with Burnout”. Available at
http://www.acgme.org/Meetings-and- Events/Annual-Educational-
Conference/Blog/Details/ArticleID/6308/Behind-the-Poster-An-Interview-with-Dr- Crystal-Jing-Jing-Yeo
Interviewed on anti-SOD1 oligonucleotides in ALS by Zakaib, Gwyneth. “Antisense Oligonucleotides: Can They
Take on ALS, SMA, Prions?” ALZFORUM, 22 May 2019, www.alzforum.org/news/conference-
coverage/antisense-oligonucleotides-can-they-take-als-sma-prions.
Publications
Yeo, C.J.J. and Darras, B.T. (2020), Yeo and Darras: Extraneuronal Phenotypes of Spinal Muscular Atrophy. Ann
Neurol. 2020 Oct 13. doi: 10.1002/ana.25930. https://doi.org/10.1002/ana.25930
Angkodjojo S, Yeo CJJ. A Patient with Limbic Encephalitis, Ear Perichondritis, and Episcleritis – An Unusual
Presentation of Relapsing Polychondritis. Case Rep Neurol 2020;12:378-386. doi: 10.1159/000510634
Yeo CJJ, Simeone SD, Townsend EL, Zhang RZ, Swoboda KJ. Prospective Cohort Study of Nusinersen Treatment in
Adults with Spinal Muscular Atrophy. J Neuromuscul Dis. 2020;7(3):257-268. doi: 10.3233/JND-190453.
Yeo CJJ, Darras BT. Overturning the Paradigm of Spinal Muscular Atrophy as just a Motor Neuron Disease. Pediatr
Neurol. 2020;S0887-8994(20)30027-8. doi:10.1016/j.pediatrneurol.2020.01.003
Yeo CJ, Ng SY, Darras BT. Reduced Spinal Motor Neuron Expression of Insulin-like Growth Factor-2 and Insulin-like
Growth Factor Binding Protein 5 in Spinal Muscular Atrophy Type 1 (1262). Neurology Apr 2020, 94 (15
Supplement) 1262
Yeo CJ, Simeone S, Zhang RZ, Trautman K, Damron B, Nwe P, Siranosian J, Johnstone A, Chen JY, Townsend E, Nery
F, Herrmann M, Swoboda K. Outcome measures for Nusinersen efficacy in Adults with Spinal Muscular Atrophy.
Neurology Apr 2019, 92 (15 Supplement) S5.008
Yeo CJ, Babieri A, Roman G, Wiesman J, Powell SZ. Using Smartphone Mindfulness Apps to Increase Trainee
Resilience and Reduce Burnout. Neurology Apr 2019, 92 (15 Supplement) P2.9-005
Yeo CJ et al. Scrubber’s Radial Palsy - Proximal Compression of the Radial Nerve at the Origin of the
Brachioradialis. Neurology Apr 2019, 92 (15 Supplement) P4.4-037
Yeo CJJ, Román GC, Kusnerik D, Burt T, Mersinger D, Thomas S, Boone T, Powell SZ. Trainee Responses to
Hurricane Harvey: Correlating Volunteerism With Burnout. Front Public Health. 2018; 6:224.
Yeo CJJ, Hutton GJ, Fung SH. Advanced neuroimaging in Balo's concentric sclerosis: MRI, MRS, DTI, and ASL
perfusion imaging over 1 year. Radiol Case Rep. 2018 Oct; 13(5):1030-1035.
Yeo CJ, Ondo W. Tremor Research Group Essential Tremor Rating Scale (TETRAS): Assessing Impact of Different
Item Instructions. Neurology Apr 2018, 90 (15 Supplement) P6.062
Yeo CJJ and Pleitez M. Eculizumab in Refractory Myasthenia Crisis. Muscle Nerve. 2018 Aug; 58(2):E13-E15.
Yeo CJJ and Simmons Z. Discussing edaravone with the ALS patient: an ethical framework from a U.S.
perspective, Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, 2018, 19:3-4, 167-172
Yeo CJJ, Britz G, Powell, S, Smith, R & Zhang, Yi. Recurrent Cerebral Hemorrhages in Normal Pregnancy Secondary
to Mycotic Pseudoaneurysms Related to Choriocarcinoma. World Neurosurg. 2018 Jan; 109:247-250.
Yeo CJ, Bunin V, Popovich J, Cykowski M, Smith R. Mitochondrial Skeletal and Cardiac Myopathy Responsive to
Aggressive Immunosuppression in Rapidly Progressing Systemic Sclerosis. Neurology Apr 2017, 88 (16
Supplement) P5.077
Yeo CJ, McCane D, Katz L, Ling K, Capetillo A, Bledsoe D, Chiu D. Variables affecting stroke outcome for t-PA
received between 3 to 4.5 hours. Neurology Apr 2016, 86 (16 Supplement) P2.301
Yeo CJ, Gilman AL. Interleukin-2-induced graft-versus-leukemia for the treatment of AML in a BRCA2
Fanconi anemia patient. Journal of Pediatric Hematology/oncology. 2014 Mar;36(2):e78-80.
Yeo CJJ, Fearon DT. T-bet-mediated differentiation of the activated CD8+ T cell. European Journal of
Immunology. 2011 Jan; 41(1):60-66.
Yeo CJJ. Ethical dilemmas of the practice of medicine in the information technology age. Singapore Med
J 2003; 44:141-4.
ePearl
Crystal Jing Jing Yeo. Neurology, May 16, 2018 e-Pearl of the Week: Antiphospholipid antibody-associated
chorea. http://n.neurology.org/epearls/20180516
Poetry
Crystal Jing Jing Yeo. Right Brain: Should we wear flowers in our hair? Neurology Oct 2018, 91 (16) 761; DOI:
10.1212/WNL.0000000000006364
Crystal Jing Jing Yeo. Haiku on Phone. Closler, Johns Hopkins Medicine June 2019. http://closler.org/passion-in-
the-medical-profession/haiku-on-phone
Patient Education
Crystal Jing Jing Yeo and Basil T. Darras. Overview of Spinal Muscular Atrophy for the Child Neurology Foundation.
June 2021
Online Education
Crystal Jing Jing Yeo and Basil T. Darras: Extraneural manifestations of Spinal Muscular Atrophy. American
Neurological Association ANA Highlights. June 2020. https://myana.org/education/ana-highlights-bite-size-
learning-cme
Crystal Jing Jing Yeo. Image Quiz: Stroke after Strenuous Gym Workout. Univadis. August 2019.
http://www.univadis.com/player/yuvvcxpfi
Crystal Jing Jing Yeo. Image Quiz: Stroke causing Seizures and Coma. Univadis. July 2019.
http://www.univadis.com/player/yuvvzxccx
News
Zakaib, Gwyneth. “Antisense Oligonucleotides: Can They Take on ALS, SMA, Prions?” ALZFORUM, 22 May 2019,
www.alzforum.org/news/conference-coverage/antisense-oligonucleotides-can-they-take-als-sma-prions.
“Women's History Month Spotlight: Crystal J. J. Yeo, MD, PhD.” Massachusetts General Hospital, Massachusetts
General Hospital, 6 Mar. 2019, www.massgeneral.org/about/newsarticle.aspx?id=7076.
Melão, Alice. “Top 10 ALS Stories of 2018.” ALS News Today, ALS News Today, 2 Jan. 2019,
alsnewstoday.com/2019/01/02/top-10-als-stories-of-2018/.
Cárdenas, Javier. “2018 PALF Class Ready to Change the World Through Advocacy.” AAN Capitol Hill Report, 21
May 2018, www.aan.com/policy-and-guidelines/advocacy/capitol-hill-report/.
“Behind the Poster: An Interview with Dr. Crystal Jing Jing Yeo.” ACGME, 7 Mar. 2018,
www.acgme.org/Meetings-and-Events/Annual-Educational-Conference/Blog/Details/ArticleID/6308/Behind-
the-Poster-An-Interview-with-Dr-Crystal-Jing-Jing-Yeo.
Blake, Donald, and Jessica Gladwell. “Radicava Approval: Reality Tempers Excitement in ALS Community.”
Patient Worthy, 4 Feb 2018, patientworthy.com/2018/02/04/radicava-reality-excitement-als-community/.
“Les Facteurs Éthiques Devraient Être Au Cœur Des Discussions.” Perspectives Cliniques Concernant Le Stress
Oxydant | Ligue SLA Belgique Asbl, 2018, als.be/fr/Facteurs-ethiques-devraient-etre-au-c%C5%93ur-
discussions-Radicava.
Kegel, Magdalena. “Present All Sides When Discussing Radica for ALS, Physicians Urge.” ALS News Today, ALS News
Today, 18 Jan. 2018, alsnewstoday.com/2018/01/18/present-all-sides-when-discussing-radicava-als-
physicians-urge/
Teaching
Bedside teaching and examination of Harvard Medical School students from 2018-2019.
NeuromuscularQandA Tweetorials at @crystalyeomdphd
Teaching of Movement Disorders module for GS6882A: Biology of Disease for NUS Physiology graduate students
Teaching of Electromyography and nerve conductions workshop for LKC School of Medicine medical students
Language Fluency
English (Native)
Chinese (Native)