Bioethics Reviewer
Bioethics Reviewer
Medical Infertility. The failure to become pregnant after twelve months of unprotected (no
contraceptive use) sexual intercourse.
Assisted Reproductive Technologies (ART). Involve extracting and combining eggs and sperm to create
embryos outside a woman’s body, which are then placed in her uterus or fallopian tubes, in an attempt
to achieve pregnancy.
Artificial Insemination (AI). Involves implanting male sperm (from the husband or from a donor) into
the woman’s vagina to aid in conception.
In vitro Fertilization (IVF). Literally means “fertilization in glass.” A fertilization that is artificially
performed outside the woman’s body—in a test tube.
Surrogate Motherhood. A woman agrees to have a child for another married heterosexual couple or for
a homosexual couple using the in vitro method. In cases in which the female is unable to produce ova so
the surrogate’s ovum or another donor’s ovum is used. The sperm may or may not be obtained from the
couple.
o Limitations on how many children a sperm donor may give rise to in order to prevent the risk of
accidental consanguinity or inbreeding between donor offspring.
o Prohibitions on the use of donor semen after the donor has died
o Banned or restricted use of donor sperm for IVF treatment to married heterosexual couples,
single women or lesbian couples. As a consequence, women travels to a country which does not
impose restrictions in a practice called fertility tourism.
HISTORY OF AI
1455 ~ Unofficial history claims that the first attempts to artificially inseminate a woman, were done
by Henry IV (1425-1474), King of Castile, nicknamed the Impotent.
1678 ~ Spermatozoa were first seen and described by Antoni van Leeuwenhoek and his
assistant Johannes Hamin in the Netherlands. In a letter to William Bounker of the Royal Society of
London he showed a picture of sperm cells of the human and the dog. van Leeuwenhoek described the
spermatozoa as “living animalcules in human semen
1784 ~ More than 100 years later, the first artificial insemination in a dog was reported by the
scientist Lazzaro Spallanzani (Italian physiologist, 1729-1799). This insemination resulted in the birth of
three puppy’s
1770s ~ The first documented application of artificial insemination in human was done in London
by John Hunter, which has been called in medical history the “the founder of scientific surgery”.
1800s ~ J Marion Sims reported his findings of postcoital tests and 55 inseminations. Only one
pregnancy occurred but this could be explained by the fact that he believed that ovulation occurred
during menstruation
1897 ~ Heape, an outstanding reproductive biologist from Cambridge, reported the use of AI in rabbits,
dogs and horses
1899 ~ The first attempts to develop practical methods for artificial insemination were described by Ilya
Ivanovich Ivanoff (Russia, 1870-1932). Although Ivanoff studied artificial insemination in domestic farm
animals, dogs, rabbits and poultry, he was the first to develop methods as we know today in human
medicine.
Milovanov, another Russian scientist. He published his paper on “Artificial insemination in Russia” in
the Journal of Heredity in 1938
The introduction of the first AI cooperative in the US in 1938 by EJ Perry, a dairyman from New Jersey. In
the US and other Western countries the number of AI cooperatives increased rapidly. Nowadays more
than 90 % of dairy cows are artificially inseminated in the Netherlands, Denmark and the United
Kingdom.
November 1, 1939, the first animal, a rabbit, conceived by artificial insemination was exhibited in the
United States at the 12th Annual Graduate Fortnight at the New York Academy of Medicine. Gregory
Pincus, an American biologist, removed an egg from the ovary of a female rabbit and fertilized it with a
salt solution. The egg was then transferred to the uterus of a second rabbit,
Phillips and Lardy (1939) were the first to use egg yolk to protect bull sperm cells from temperature
shock upon cooling. This protection was explained by the effect of phospholipids and lipoproteins in the
egg yolk
Polge and co-workers (1949) were the first to freeze fowl and bull spermatozoa by using glycerol in the
extender media. In 1950 Cornell University scientists (New York)
In 1953 Dr. Jerome K. Sherman, an American pioneer in sperm freezing, introduced a simple method of
preserving human sperm using glycerol.
the first successful human pregnancy with frozen spermatozoa was reported in 1953
o ARTIFICIAL INSEMINATION - Involves implanting male sperm (from the husband or from a
donor) into the woman’s vagina to aid in conception.
REASONS FOR AI
A. Male:
3. Neurological condition that makes ejaculation impossible or from a disease (e.g. diabetes) that
renders the man impotent
B. Female:
3. The couple may be carriers of a recessive gene for a genetic disorder (e.g. Tay-Sachs disease),
or the male may be the carrier of a dominant gene for a genetic disorder (e.g. Huntington’s
disease).
RECIPIENT OF AI
2. Single women
3. Lesbian couples
IN- VITRO FERTILIZATION - A method of assisted reproduction in which a man's sperm and a woman's
eggs are combined outside of the body in a laboratory dish.
The main reason for the renewed interest in AI in human was undoubtedly the introduction of IVF in
1978 by Steptoe and Edwards.
In the early days the ejaculate of the husband was inseminated intrauterine without preparation
resulting in uterine cramps and increasing the probability of tubal infections.
With the arrival of IVF, semen preparation techniques were developed and IUI regained its popularity,
being more safe and painless.
IVF was initially used to treat women with blocked, damaged, or absent fallopian tubes.
in women with advanced maternal age where her chances for pregnancy are rapidly declining and IVF
remains as the best possible option
DURATION
The average time that is required to complete one IVF cycle (from start of ovarian stimulation to testing
for pregnancy) is about four to six weeks, depending on the chosen ovarian stimulation protocol
appropriate for your case.
Intracytoplasmic Sperm Injection (ICSI)? ICSI - the step in the IVF process which aims to
achieve fertilization for the collected eggs.
- a single sperm is directly injected into each mature egg. It is usually performed when there is a
likelihood of reduced fertilization, i.e., poor semen quality, history of failed fertilization in a prior IVF
cycle, etc.
SUCCESS OF IVF
1.women’s age,
-success rates vary from center to center and between practicing clinicians.
SURROGACY MOTHERHOOD
HISTORY
Biblical Times.
The first mention of surrogacy can be found in “The Book of Genesis” in the story of Sarah and
Abraham. Hegar was the surrogate mother. This is a case of traditional surrogacy, where the surrogate
uses her own egg in the child she’s carrying for intended parents.
1884. The first successful AI of a woman was completed, although in an ethically questionable way. This
paved the way for future AIs used in the surrogacy process.
1975. The first ethically completed IVF embryo transfer was successful.
1976. The first legal surrogacy agreement in the history of surrogacy was brokered by lawyer Noel
Keane.
This was a traditional surrogacy, and the surrogate did not receive any compensation for the pregnancy
1984–1986. Perhaps the most famous case in surrogacy history is the “Baby M.” case, involving a
traditional surrogacy. Bill and Betsy Stern hired Mary Beth Whitehead to be their surrogate in 1984,
agreeing to pay her $10,000. Whitehead’s eggs were used in the AI process, making her the biological
mother of the child. Custody was granted to Bill Stern, with Whitehead receiving visitation rights.
Reasons for taking surrogacy
o Either male or female or both are found to be infertile;
o or congenital abnormality such as small uterus or bicornate uterus because of which the female
cannot bear the child normally.
4. Children can even be conceived after their father’s death, by using stored frozen sperm
or sperm retrieved immediately postmortem.
o the practice of freezing and storing an embryo as if it were an object, interrupting the
natural development of life, violates the dignity that is enjoyed by a human being from
the very moment of conception;
o in all cases, it dissociates the two aspects of the human act, union and procreation, since
procreation is sought separately from the conjugal relation.
- Heterologous artificial fertilization is contrary to the unity of marriage, to the dignity
of the spouses, to the vocation proper to parents, and to the child's right to be conceived
and brought into the world in marriage and from marriage.
- Fertilization of a married woman with the sperm of a donor different from her husband
and fertilization with the husband's sperm of an ovum not coming from his wife are
morally illicit.
- Artificial fertilization of a woman who is unmarried or a widow, whoever the donor may
be, cannot be morally justified
- The Church remain opposed from the moral point of view to homologous 'in vitro'
fertilization. Such fertilization is in itself illicit and in opposition to the dignity of
procreation and of the conjugal union, even when everything is done to avoid the death
of the human embryo.
- SURROGATE MOTHERHOOD is not morally LECIT because it is contrary to the unity
of marriage and to the dignity of the procreation of the human person.
- Surrogate motherhood represents an objective failure to meet the obligations of maternal
love, of conjugal fidelity and of responsible motherhood
Morality of
Abortion, Rape, and other problems related to the Destruction of Life
ABORTION - The deliberate removal (or deliberate action to cause the expulsion) of a fetus from the
womb of a human female, at the request of or through the agency of the mother, so as in fact to result
in the death of the fetus.
It can occur spontaneously (usually termed miscarriages) due to complications during pregnancy or can
be induced
Constitution of the Republic of the Philippines (1987), Article II, Section 12 The Revised Penal
Code of the Philippines,
Act No. 3815 of December 8, 1930, Articles 256-259
Art. 256. Intentional abortion. – Any person who shall intentionally cause an abortion shall
suffer:
1. The penalty of reclusion temporal, if he shall use any violence upon the person of the
pregnant woman.
2. The penalty of prision mayor if, without using violence, he shall act without the consent
of the woman.
3. The penalty of prision correccional in its medium and maximum periods, if the woman
shall have consented.
Art. 257. Unintentional abortion. – The penalty of prision correccional in its minimum and medium
period shall be imposed upon any person who shall cause an abortion by violence, but
unintentionally.
Art. 258. Abortion practiced by the woman herself of by her parents. – The penalty of prision
correccional in its medium and maximum periods shall be imposed upon a woman who shall
practice abortion upon herself or shall consent that any other person should do so.
Any woman who shall commit this offense to conceal her dishonor, shall suffer the penalty of
prision correccional in its minimum and medium periods.
If this crime be committed by the parents of the pregnant woman or either of them, and they act
with the consent of said woman for the purpose of concealing her dishonor, the offenders shall
suffer the penalty of prision correccional in its medium and maximum periods.
Art. 259. Abortion practiced by a physician or midwife and dispensing of abortives. – The penalties
provided in Article 256 shall be imposed in its maximum period, respectively, upon any physician or
midwife who, taking advantage of their scientific knowledge or skill, shall cause an abortion or assist
in causing the same.
Any pharmacist who, without the proper prescription from a physician, shall dispense any abortive
shall suffer arresto mayor and a fine not exceeding 1,000 pesos.
TYPES OF ABORTION
1. Miscarriage, or spontaneous abortion, is due to causes that are beyond human control. It has
no moral qualification.
- The right to life does not come from the parents, society, nor any human authority; it
comes directly from
God. Therefore, nobody may dispose of another’s life, neither as an end nor as a means.
induced abortion is thus intrinsically evil, and must be qualified as homicide.
Health care workers have particular obligations toward aborted fetuses. An aborted fetus, if still alive,
must be baptized (“Emergency Baptism”).
An aborted fetus that is already dead deserves the respect owed to a human corpse, and if possible it
should be given a suitable burial.
TYPES OF BAPTISM
Proximate Matter: the application of water to the body of the candidate by way of a triple immersion in
water,or by a triple effusion of it.
Remote Matter: true and natural water. In case of necessity,what is still commonly called and
considered water may be used,even if it is mixed with other substances.
Form:“(Name),I baptize you in the name of the Father and of the Son and of the Holy Spirit.”
RAPE
An unlawful sexual activity and usually sexual intercourse carried out forcibly or under threat of
injury against a person's will or with a person who is beneath a certain age or incapable of valid
consent because of mental illness, mental deficiency, intoxication, unconsciousness, or
deception.
TYPES OF RAPE
1. Date Rape. A non-domestic rape committed by someone who knows the
victim, and drug facilitated sexual assault (DFSA), where the rapist intentionally drugs
the victim with a date rape drug so that they are incapacitated.
2. Gang Rape. Occurs when a group of people participate in the rape of a single victim.
3. Spousal Rape. also known as marital rape, wife rape, husband rape, partner rape
or intimate partner sexual assault (IPSA), is rape between a married or de facto couple
without one spouse's consent. Spousal rape is considered a form of domestic
violence and sexual abuse.
4. Rape of Children. Rape of a child is a form of child sexual abuse.
When committed by another child (usually older or stronger) or adolescent, it is called child-
on-child sexual abuse.
- Committed by parents, close relative- called INCEST
- Not by family members but by caregiver, teacher, religious authorities, on whom a child
is dependent is called INCESTUAL RAPE.
5. Statutory Rape. Sexual activity that violates age-of-consent law, but is neither violent
nor physically coerced. MINOR child 12 years and below.
6. Prison Rape.
7. War Rapes. Are rapes committed by soldiers, other combatants or civilians during armed
conflict or war
8. Serial Rape. Is rape committed by a person over a relatively long period of time and
committed on a number of victims
9. Rape by Deception. Occurs when the perpetrator gains the victim's agreement
through fraud. In one case, a man pretended to be an official for a government who had
power to cause negative impacts on a woman to pressure a woman into sexual activities.
10. Corrective Rape. Is targeted rape against non-heterosexuals as a punishment for
violating gender roles. It is a form of hate crime against LGBT individuals, mainly
lesbians, in which the rapist justifies the act as an acceptable response to the victim's
perceived sexual or gender orientation and a form of punishment for being gay.
11. Custodial Rape. Is rape perpetrated by a person employed by the state in a supervisory
or custodial position, such as a police officer, public servant or jail or hospital employee
8.Any other sexual conduct that is harmful to a child's mental, emotional, or physical welfare
1. She must receive spiritual and psychological support and counseling to help her deal with the
trauma of the attack.
2. Health care providers need to cooperate with law enforcement officials, gathering evidence that
can be used in the prosecution of the rapist.
EUTHANASIA
• ITS TYPES, CATEGORIES & OTHER CLASSIFICATION
Commission (Active); Omission (Passive)
Voluntary, Non-voluntary & Involuntary
Suicidal, Homicidal, Ortothanasia, Dysthanasia
From the Greek word “Eu” (good) and “Thanatos” (death), signifies good death,
a pleasant, gentle death, without awful suffering.
The act of practice of permitting the death of hopelessly sick or injured
individuals in relatively painless way for reasons of mercy. It is commonly called
merciful killing to relieve suffering.
(Sacred Congregation for the Doctrine of the Faith) is understood an action of
omission which, of itself or by intention causes death, or in order that all
suffering may in this way be eliminated.
TYPES OF EUTHANASIA:
Euthanasia by Commission (Active Euthanasia) – refers to the positive act of
causing death that is geared towards termination of pain & suffering. By positive
act is meant a measure necessary to end the life of a suffering person in directly
use. E.g. a lethal dose is injected into the terminally ill patient to cause
immediate death.
Euthanasia by Omission (Passive Euthanasia) – the negative act of causing death
that is geared towards termination of pain & suffering. By negative act is meant a
measure necessary to sustain the life of a suffering person is omitted, withheld
or withdrawn. E.g. food & water are withdrawn to bring about the earlier death
of a terminally ill patient.
• TYPES OF EUTHANASIA
Voluntary Euthanasia – indicates the measure of causing the death of the patient
at his willful consent or request. It could be expressed, written in the patient’s
advance directive as in a living will or durable power of attorney or given by
mere gesture in case of inability to speak & manage oneself. This is currently
legal in Belgium, Luxembourg, The Netherlands, Switzerland, and the states of
Oregon and Washington in the U.S.
Non-voluntary Euthanasia – indicates the measure of causing death of the
patient who is unable to express his will & make his intentions known as in
unconscious or comatose state. The decision to end the patient’s life is made
either by the watchers of the patient, health care team or the society.
Involuntary Euthanasia – indicates the measure of causing the death of the
patient in defiance of his expressed will and/or against his consent.
OTHER CLASSIFICATION OF EUTHANASIA
• Suicidal Euthanasia – subject himself (alone or with help of other people) resorts to
lethal means to interrupt or suppress his life. Done with the subject’s consent.
• Homicidal Euthanasia – Euthanasia for piety or pious homicide, performed to liberate a
person from a terrible disease. It prescribes “death without suffering” for hopeless
patients, saving them from further “useless”, “unnecessary” suffering.
• Ortothanasia – etymologically, means passive death. Subject is left to die by omitting
any medical assistance. Some authors defines it as “just death” or death in its due time,
which is considered ethical. The mere allowing & acceptance of natural death in its
definitely inescapable occurrence in due time as the final moment of one’s earthly life. A
normal or natural manner of death and dying. Sometimes used to denote the deliberate
stopping of artificial or heroic means of maintaining life.
• Dysthanasia – the undue prolongation of life & delay of the occurrence of natural death
which in effect lengthens the suffering of the person. It is a term generally used when a
person is seen to be kept alive artificially in a condition where, otherwise, they cannot
survive; sometimes for some sort of ulterior (intentionally hidden/future) motive.
ADVANCE DIRECTIVES
• Are legal documents that allow you to spell out your decisions about end- of-life care
ahead of time. They give you a way to tell your wishes to family, friends, and health care
professionals and to avoid confusion later on.
• Forms of Advance Directives:
1) The living will is a legal document used to state certain future health care
decisions only when a person becomes unable to make the decisions and choices
on their own.
2) Durable power of attorney for health care/Medical power of attorney is a legal
document in which you name a person to be a proxy (agent) to make all your
health care decisions if you become unable to do so.
DNR OR END OF LIFE CARE
• Do Not Resuscitate (DNR), also known as no code or allow natural death, is a legal
order, written or oral depending on country, indicating that a person does not want to
receive cardiopulmonary resuscitation (CPR) if that person's heart stops beating.
Sometimes it also prevents other medical interventions. The legal status and processes
surrounding DNR orders vary from country to country. Most commonly, the order is
placed by a physician based on a combination of medical judgement and patient wishes
and values.
• Palliative Care & Hospice Care
• End of life care includes palliative care. If you have an illness that can't be cured, based
on the understanding that death is inevitable. palliative care makes you as comfortable
as possible, by managing your pain and other distressing symptoms. It also involves
psychological, social and spiritual support for you and your family or careers.
• WHEN DOES END OF LIFE CARE BEGIN? Have an advanced incurable illness, such as
cancer, dementia or motor neuron disease are generally frail and have co-existing
conditions that mean they are expected to die within 12 months •have existing
conditions if they are at risk of dying from a sudden crisis in their condition •have a life-
threatening acute condition caused by a sudden catastrophic event, such as an accident
or stroke.
ACUTE CARE PLANNING
A key component of holistic care is making assessment that include planning for the
future.
It anticipates deterioration and explores what the patient & family want to do when the
time comes.
The process involves & allows open discussion between the patient, family members &
the multidisciplinary team.
NURSES ROLE AND REPONSIBILITIES IN END OF LIFE CARE
1) Treat people compassionately.
2) Listen to people
3) Communicate clearly and sensitively .
4) Identify and meet the communication needs of each individual.
5) Acknowledge pain and distress and take action.
6) Recognize when someone may be entering the last few days and hours of life.
7) Involve people in decisions about their care and respect their wishes.
8) Keep the person who is reaching the end of their life and those important to them up to
date with any changes in condition.
9) Document a summary of conversations and decisions.
10) Seek further advice if needed.
11) Look after yourself and your colleagues and seek support if you need it.
12) Learning from complaints.
13) Care of the person.
CRUCIAL ROLE OF A NURSE IN PALLIATIVE CARE
1) Teacher / Health Educator
2) Counselor
3) Caregiver
4) Advocate
5) Messenger - help patients in establishing advance care planning decisions by asking,
listening & guiding.
ETHICAL DECISION MAKING
Choosing among alternatives in a manner consistent with ethical principles. In making
ethical decisions, it is necessary to perceive and eliminate unethical options and select
the best ethical alternative.
The process of making ethical decisions requires:
1) Commitment: The desire to do the right thing regardless of the cost
2) Consciousness: The awareness to act consistently and apply moral convictions to
daily behavior
3) Competency: The ability to collect and evaluate information, develop
alternatives, and foresee potential consequences and risks
Good decisions are both ethical and effective:
1) Ethical decisions generate and sustain trust; demonstrate respect, responsibility,
fairness and caring; and are consistent with good citizenship. These behaviors
provide a foundation for making better decisions by setting the ground rules for
our behavior.
2) Effective decisions are effective if they accomplish what we want accomplished
and if they advance our purposes. A choice that produces unintended and
undesirable results is ineffective. The key to making effective decisions is to think
about choices in terms of their ability to accomplish our most important goals.
This means we have to understand the difference between immediate and short-
term goals and longer-range goals.
Making Ethical Decisions: Model
ETHICAL DECISION MAKING PROCESS