562075LX

THE TAMIL NADU DR. M.G.R.
MEDICAL UNIVERSITY
[BPHARM 1221] DECEMBER 2021 Sub. Code: 2075

(MARCH 2021 EXAM SESSION)
B. PHARMACY DEGREE EXAMINATION

PCI Regulation SEMESTER - VII
PAPER IV - NOVEL DRUG DELIVERY SYSTEM
Q.P. Code : 562075
Time: Three hours Maximum: 75 Marks
I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)
1. Discuss about the polymers in controlled release drug delivery system.

2. Write about the implantable drug delivery system.
3. Discuss about the ocular drug delivery system.
II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)
1. Advantages and disadvantages of controlled drug delivery system.

2. Coacervation - phase separation method.
3. Basic components of Transdermal drug delivery system.
4. Floating drug delivery system.
5. Nasal drug delivery system.
6. Approaches of targeted drug delivery system.
7. Intra uterine drug delivery system.
8. Preparation of monoclonal antibodies.
9. Pulmonary drug delivery system.
III. Short answers on: Answer ALL questions. (10 x 2 = 20)
1. Terminology of controlled drug delivery system.

2. Characteristics of ideal polymers.
3. Advantages of microencapsulation.
4. Stages of mucoadhesion.
5. List out evaluation test of Transdermal drug delivery system.
6. Mucoadhessive drug delivery system.
7. Targeted drug delivery system.
8. Nanoparticle.
9. Inserts.
10. Types of intrauterine device.
*******
THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[BPHARM 0522] MAY 2022 Sub. Code: 2075

(SEPTEMBER 2021 EXAM SESSION)

PCI Regulation SEMESTER - VII
Q.P. Code : 562075
1. Discuss about the approaches to design controlled release formulation.

2. Write about the liposomes targeted drug delivery system.
3. Write about the methods of microencapsulation.
1. Applications of nasal drug delivery system.

2. Metered dose inhalers.
3. Niosomes.
4. Applications of monoclonal antibodies.
5. Intrauterine device.
6. Barriers to ocular drug delivery system.
7. Evaluation of nanoparticles.
8. Factors affecting permeation of Transdermal drug delivery system.
9. Dissolution controlled release system.
1. Advantages of controlled drug delivery.

2. Natural Polymers.
3. Advantages of micro encapsulation.
4. Air suspension techniques.
5. Drugs suitable for Gastro-retentive drug delivery system.
6. Floating drug delivery system.
7. Advantages of transdermal drug delivery systems.
8. Applications of niosomes.
9. Ocuserts.
10. Application of nanoparticle.
*******
[BPHARM 1022] OCTOBER 2022 Sub. Code: 2075


PCI Regulation 2017 - SEMESTER VII
Q.P. Code : 562075
1. Write the concept of controlled drug delivery system. Explain the approaches for
the controlled release formulations based on dissolution.
2. State various methods to prepare liposomes.
3. What is an implant? Explain the formulation of implants with a suitable example.
1. Write methods of preparing nanoparticle.

2. Explain about microballoons as gastroadhesive drug delivery system.
3. Describe the components of transdermal DDS.
4. Discuss in detail about mucosal drug delivery system.
5. What are niosomes? Write its applications in targeted drug delivery system.
6. Explain the pharmaceutical applications of microspheres.
7. Describe in detail about formulations aspects of Nasal spray.
8. Write mechanism of controlled drug release in ophthalmic drug delivery.
9. Discuss briefly on intra-vaginal drug delivery system.
1. Define Microencapsulation technique.

2. Biological half- life.
3. Application of intrauterine drug delivery system.
4. What is Transdermal drug delivery system?
5. Define buccal drug delivery system.
6. Apparent volume of distribution.
7. Iontophoresis.
8. What are the ideal requirements of ocular drug delivery system?
9. Nebulizer.
10. Gastroretentive drug delivery system.
*******
[B.PHARM 0323] MARCH 2023 Sub. Code: 2075

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

PCI Regulation 2017 – SEMESTER - VII
Q.P. Code: 562075

1. Explain the principle involved in the design of controlled drug delivery system.
2. Define Microencapsulation. Write the applications of microencapsulation. Explain
phase separation – coacervation technique.
3. Define liposomes. Explain the different methods of preparation of liposomes.
1. Write a note on the formulation of buccal drug delivery system.

2. Explain concept, advantages, disadvantages of implants.
3. Explain any one formulation approaches for transdermal drug delivery system.
4. Classification of polymers.
5. What is nasal drug delivery system? Write about its advantages and disadvantages.
6. Describe about hormonal intrauterine drug delivery system.
7. What are niosomes? Write its applications in target drug delivery system.
8. Explain concept, advantages and disadvantages of nanoparticle.
9. Explain the characteristics of ocular drug delivery system.
1. Define controlled release and sustained release.

2. Define half life and protein binding.
3. Define core and coat materials with respect to microencapsulation.
4. Dry powder inhaler.
5. Iontophoresis.
6. Gastroretentive drug delivery system.
7. Intravitreal injection.
8. Nebulizer.
9. Define dissolution and diffusion.
10. Spray drying and spray congealing.
*******
[B.PHARM 0823] AUGUST 2023 Sub. Code: 2075


PCI Regulation 2017 - SEMESTER - VII
Q.P. Code: 562075

1. Define microencapsulation. Write in detail about methods of microencapsulation.

2. Enumerate the approaches for GRDDS.
3. Describe intra ocular barriers and methods to overcome it.
1. Selection of drug for controlled release preparations.

2. Transmucosal permeability.
3. Application of polymers.
4. Classification of Polymeric Implants.
5. Factors affecting skin permeation.
6. Formulation of inhalers.
7. Classification of liposomes.
8. Niosomes.
9. Applications of intrauterine drug delivery systems.
1. Hormone Releasing Intrauterine Devices.

2. Targeted Drug Delivery.
3. Osmogen.
4. ALZET Pump.
5. Sustained Drug Release.
6. Nasal Spray.
7. Monoclonal antibodies.
8. Matrix Diffusion System.
9. Ocusert.
10. Iontophoresis.
*******
[B.PHARM 1223] DECEMBER 2023 Sub. Code: 2075


PCI Regulation 2017 - SEMESTER - VII
Q.P. Code: 562075

1. Enumerate about of design and approaches of controlled release formulations.

2. Write in detail about basic components of transdermal drug delivery system and its
formulation.
3. Describe about nanoparticles in targeted drug delivery system.
1. Applications of microencapsulation.
2. Principles of bioadhesion.
3. Intra uterine devices.
4. Monoclonal antibodies.
5. Metered dose inhalers.
6. Osmotic pump.
7. Classification of polymers.
8. Permeation enhancers.
9. Intra ocular barriers.
1. Extended release.
2. Mucoadhesive polymer.
3. Microcapsules.
4. Implants.
5. Gastroretentive drug delivery systems.
6. Nebulizer.
7. Classification of liposomes.
8. Skin permeation pathways.
9. Ocuserts.
10. Niosomes.
*******

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THE TAMIL NADU DR. M.G.R.

[BPHARM 1221] DECEMBER 2021 Sub. Code: 2075

B. PHARMACY DEGREE EXAMINATION

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Discuss about the polymers in controlled release drug delivery system.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Advantages and disadvantages of controlled drug delivery system.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Terminology of controlled drug delivery system.

[BPHARM 0522] MAY 2022 Sub. Code: 2075

B. PHARMACY DEGREE EXAMINATION

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Discuss about the approaches to design controlled release formulation.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Applications of nasal drug delivery system.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Advantages of controlled drug delivery.

[BPHARM 1022] OCTOBER 2022 Sub. Code: 2075

B. PHARMACY DEGREE EXAMINATION

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Write methods of preparing nanoparticle.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Define Microencapsulation technique.

[B.PHARM 0323] MARCH 2023 Sub. Code: 2075

B.PHARMACY DEGREE COURSE (SEMESTER EXAMINATIONS)

Q.P. Code: 562075

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Write a note on the formulation of buccal drug delivery system.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Define controlled release and sustained release.

[B.PHARM 0823] AUGUST 2023 Sub. Code: 2075

B. PHARMACY DEGREE EXAMINATION

Q.P. Code: 562075

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Define microencapsulation. Write in detail about methods of microencapsulation.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

1. Selection of drug for controlled release preparations.

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

1. Hormone Releasing Intrauterine Devices.

[B.PHARM 1223] DECEMBER 2023 Sub. Code: 2075

B. PHARMACY DEGREE EXAMINATION

Q.P. Code: 562075

I. Elaborate on: Answer any TWO questions. (2 x 10 = 20)

1. Enumerate about of design and approaches of controlled release formulations.

II. Write notes on: Answer any SEVEN questions. (7 x 5 = 35)

III. Short answers on: Answer ALL questions. (10 x 2 = 20)

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