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    Resume Dr. Carla Moran, MRCPI, FRCPI, PHD (Irlandia)

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    Resume Dr. Carla Moran, MRCPI, FRCPI, PHD (Irlandia)

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    mirsal rizky
    23 views3 pages

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    resume Dr. Carla Moran, MRCPI, FRCPI, PhD (Irlandia)

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    Resume Dr. Carla Moran, MRCPI, FRCPI, PHD (Irlandia)

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    Dr.

    Carla Moran, MRCPI, FRCPI, PhD


    (Irlandia) Lampiran 2
    CURRICULUM VITAE

    Spesialis

    Riwayat Pendidikan
    Pendidikan Dokter :
    Spesialis :
    Fellowship :
    Sub-spesialis :
    Program Doktor :
    Postdoc :

    Organisasi



    Kontak 

    Alamat:

    Publikasi Terbaru
    Telp/Hp: -




    Email:

    LinkedIn (bila ada):

    Institusi:
    Lampiran 3

    RESUME TOPIK

    Pemateri
    Dr. Carla Moran, MRCPI, FRCPI, PhD (Irlandia)

    Judul
    “Funny Thyroid Function Tests - Avoiding The Pitfalls”
    Pendahuluan
    The thyroid gland is a butterfly-shaped endocrine gland that is normally located in the lower front of the
    neck. Laboratory determinations of thyroid function are useful in distinguishing patients with
    euthyroidism (normal thyroid gland function) from those with hyperthyroidism (increased function) or
    hypothyroidism (decreased function)
    Tujuan

    THYROID FUNCTION TESTS indications, Suspicion of thyroid disease based on clinical signs and
    symptoms, Screening for thyroid disease, Evaluation of treatment for thyroid disease.

    Definisi (bila ada)

    Thyroid function tests (TFTs) are amongst the most commonly requested laboratory investigations in
    both primary and secondary care. Fortunately, most TFTs are straightforward to interpret and confirm
    the clinical impression of euthyroidism, hypothyroidism or hyperthyroidism. However, in an important
    subgroup of patients the results of TFTs can seem confusing, either by virtue of being discordant with the
    clinical picture or because they appear incongruent with each other [e.g. raised thyroid hormones (TH),
    but with non-suppressed thyrotropin (TSH), raised TSH, but with normal TH].

    Prevalensi/insidensi (bila ada)

    TRβ RTH has an estimated incidence of 1 in 40–50,000 live births. Thyrotropinomas are considered to be
    the rarest of the classical pituitary tumours, accounting for less than 2% of all adenomas, and with an
    estimated prevalence of 1 case per million populatio. However, a recent report suggests that this
    historical figure may be changing (increasing 2–3 fold), as a consequence of increasing awareness among
    clinicians, coupled with the greater combination screening with T4 (T3) and ultrasensitive TSH assays,
    and increased availability of high resolution pituitary imaging.

    Patomekanisme

    METHODS USED TO MEASURE THYROID HORMONES, Radioimmunoassay, Enzyme-linked


    immunosorbant assay, Chemiluminescent immunoassay, Fluorescent immunoassay

    Pendekatan Diagnostik
    One of the best thyroid function screening test Elevated TSH (>5 mU/L) Hypothyroidism, Low TSH
    (<0.5 mU/L) hyperthyroidism
    Pendekatan Tatalaksana

    When interpreting TFTs it is helpful to keep in mind the seven major patterns that may be encountered
    and the conditions/circumstances in which these can arise (Fig. 2). Decisions on whether to initiate
    further investigations or the choice of laboratory, radiological and genetic tests to pursue, can then be
    focused with a view to confirming or excluding specific diagnoses.

    Update/Isu Terkini

    Although most thyroid function test patterns are easy to interpret, and concordant with
    clinical assessment of thyroid status, a small but important subset of patients exhibit results that are
    either discordant with the clinical picture or not congruent with each other. In such cases, a structured
    approach to further assessment is essential to avoid unnecessary/inappropriate investigation and
    treatment. Once confounding influences [e.g. physiological changes of age, pregnancy, intercurrent (non-
    thyroidal) illness or concomitant medication use] have been excluded, close liaison with the clinical
    biochemistry laboratory is required to systematically exclude thyroid hormone and TSH assay
    interference. Only then should further investigation for rare acquired and genetic causes of
    anomalous/discordant TFTs be considered. An algorithm summarizing this approach to investigation and
    differential diagnosis is shown in.

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