Sickle Cell

Download as rtf, pdf, or txt
Download as rtf, pdf, or txt
You are on page 1of 3

Sickle cell disease

The term sickle cell disease (SCD) describes a


group of inherited red blood cell disorders. People
with SCD have abnormal hemoglobin, called
hemoglobin S or sickle hemoglobin, in their red
blood cells.Hemoglobin is a protein in red blood cells
that carries oxygen throughout the body.“Inherited”
means that the disease is passed by genes from
parents to their children. SCD is not contagious. A
person cannot catch it, like a cold or infection, from
someone else.
People who have SCD inherit two abnormal
hemoglobin genes, one from each parent. In all
forms of SCD, at least one of the two abnormal
genes causes a person’s body to make hemoglobin
S. When a person has two hemoglobin S genes,
Hemoglobin SS, the disease is called sickle cell
anemia. This is the most common and often most
severe kind of SCD.
The red cell sickling and poor oxygen delivery can
also cause organ damage. Over a lifetime, SCD can
harm a person’s spleen, brain, eyes, lungs, liver,
heart, kidneys, penis, joints, bones, or skin. Sickle
cells can’t change shape easily, so they tend to burst
apart or hemolyze. Normal red blood cells live about
90 to 120 days, but sickle cells last only 10 to 20
days.
Most children with SCD are pain free between
painful crises, but adolescents and adults may also
suffer with chronic ongoing pain.

You might also like