i it ear fekearet ongieare atk eles, reaiagey11 sh SREE CHITRA TIRUNAL INSTITUTE FOR MEDICAL SCIENCES & TECHNOLOGY y THIRUVANANTHAPURAM—695 011 ENTRANCE EXAMINATION - ACADEMIC SESSION JANUARY 2022 Program: PhD Bioengineering ‘Time:90 Minutes Max. Marks: 100 (Select the most appropriate answer) (There are no negative marks for wrong answers) 1 The ideal Op — Amp has the following characteristics. (Ri - input impedance, A - gain, Ro - ce. Ri d. Ri 2 Ina fll wave rectifier, the current in each diode flows for : a, whole cycle of the input signal c. more than half cycle of the input signal b. half cycle of the input signal 4. none of these 3 ‘The power dissipated by a transistor approximately equals the collector current times: a. base emitter voltage ¢. collector emitter voltage b. base supply voltage d. 0.7V 4 The number FF in hexadecimal system has equivalence in decimal system to a. 128 c. 30 b. 256 4. 255 5 A system with an input x(f) and output y(t) is described by the relation: y(t)=t. x(t). This, system is: a, linear and time-invariant ¢. non-linear & time-invariant b. linear and time-varying d. non-linear and time-varying 6 A bulb ina staircases has two switches, one switch being at the ground floor and the other one at the first floor. The bulb can be turned ON and also can be tumed OFF by any one of the switches irrespective of the state of the other switch. The logic of switching of the bulb resembles: a, an AND gate ¢. aNAND gate b. an OR gate d. an XOR gate 1 Two capacitors of 2 nF and 4 uF capacitance are connected in series across a 30 V de battery. After the capacitors have been charged, the voltage across them will be a, 15Veach ce. 20V and 10V b. 10V and 20V d. 30V each Page 1 of 1010 ML 12 3 14 15 16 7 18 Ifa signal of 200Hz frequency is sampled at 300Hz, what will be the frequency of the sampled signal? a. 100Hz ©. 300Hz b. 200Hz 4. 400Hz Stroke affects which of the following body organ? a. heart c. liver b. brain d. lungs ‘What does the grey matter in the brain consist of? a, Muscle cells c, Nerve axons b. Collagen 4, Neurons Which node is called the pacemaker of the heart? a. AV Node c, Lymph Node b. SA Node d. Nodes of Ranvier ‘The set of coronary arteries supply blood to a. heart ©. liver b. brain d. eyes The CMRR ofa differential amplifier is 100dB and its gain is 1000. If for an input signal the common mode voltage is 10V and differential voltage is mV what is the output voltage? a IV e LIV b. 1LOIV d. 2V Alloy steel most widely used in implantable medical devices is a, SS 304 c. SS316L, b. SS 309 d. S$ 409 A transistor can be used in which of the following modes a. Active cc. Saturation b. Cutoff d. All three If the resultant of two forces is equal to either of them, then the angle between the forces is, a. 30° c. 90° b. 60" d. 120° A particle starts from rest with a constant acceleration a m/s” and after some time it deccelerates at a uniform rate of f m/s2. Ifthe total time taken between the two rest positions is t, the maximum velocity acquired by the particle is a. (a+Byt/2 c. (aBla+B)t b. GB) d. (a +B/a-B)t ‘A car moving with speed u can be stopped in minimum distance x when brakes are applied. If the speed becomes n times, the minimum distance over which the car can be stopped takes the value a. xin ce. xin? b. nx dx Page 2 of 1019 20 21 22 23 24 25 26 27 28 29 ‘The stress at which a material fractures under large number of reversals of stress is called a. Endurance limit c. Ultimate strength b. Creep d. Residual Stress ‘A test specimen is stressed slightly beyond the yield point and then unloaded. Its yield strength will a, decrease c. remains the same b. increase d. becomes equal to ultimate tensile strength ‘A ductile structure is defined as one in which the plastic deformation before fracture a. Is smaller than the elastic deformation cc. Is equal to elastic deformation b. vanishes d. Is much larger than elastic deformation When the strain in a material increases with time under sustained constant stress the phenomenon is known as a, Strain Hardening ©. Creep b. Hysteresis d. Visco-elasticity ‘The exact analysis of viscous flow problems can be made by a, Eulers equation ¢. Bemoulli’s equation b. Hagen Poiseuille’s d. Navier Stokes equation uation When a shear stress is applied toa substance itis found to resist it by static deformation, The substance is a a. liquid ©. gas b. solid d. uncertain ‘An abrupt change in cross section causes a, Fatigue ©. Stress Concentration b. Creep d. None of these Inthe d.c. equivalent circuit of a transistor amplifier, the capacitors are considered a. Short c. Partially short b. Open d. None of the above The purpose of d.c. conditions in a transistor is to a. Reverse bias the emitter c. Set up the operating point b. Forward bias the collector d. None of the above If a three-stage amplifier has individual stage gains of 10 db, 5 db and 12 db, then total gain in dbis a. 600 db ©. 14db b. 24db 4. 27db A sine wave voltage is applied across a capacitor. When the frequency of the voltage is decreased, the current a. Ceases ¢. increases b. decreases dd. remains constant Page 3 of 1030 31 32 33 34 35 36 37 38 39 40 The Op-amp can amplify a. ac signals only ¢. both ac and de signals b. de signals only 4. neither ac or de signals ‘The formation of this type of bond between atoms requires electrons to be shared: a. Ionic ¢. Intermittent b. Covalent 4d. Tight ‘Young's modulus of a material reflects its ability to: a. Accelerate deformation due to an c, Accommodate shock due to impact load applied load 4d, Resist deformation caused by an applied b. Induce structural changes load What is common among mild steel, 316L medical grade steel and tool steel? a Ti c. Fe b. Cu au A___ stress is generated when two materials of varying CTE are rigidly connected and subjected to a temperature change? a, Flow Uniform b. Thermal d. Transverse Composites are combinations of two materials, referred to as: a, Matrix & reinforcing phases ¢, Equimolar phases b. Strong and weak phases 4. Solvent and solute phases ‘The cross-product of two vectors P andQ is a maximum when Pand Qare: a. Parallel to each other c, Perpendicular b. 45° to each other 4. Anti-parallel During a forward somersault dive performed by a springboard diver, the following physical quantity is conserved: a, Rotational inertia c. Angular momentum b. Angular Speed 4. Acceleration ‘A solid object placed in a fluid under high pressure is compressed uniformly on all sides. This type of stress is referred to as: a, Hydrostatic c. Compressive b. Shear d. Load bearing “The normal blood pressure (systolic pressure) of a healthy individual reads "120° on the physician's pressure gauge. What are the units of this pressure? a KPa ce. Nmm? b. torr 4d. microns ‘A tube of fluid flow is defined by streamlines that form its boundary. This attribute of the fluid must be the same for all cross-sections of the tube of flow: a. Velocity ©. Flow rate b. Pressure d. Direction Page 4 of 1041 42 43 45 46 47 48 49 50 Sl All mechanical structures have one or more natural frequencies. If a structure is subjected to a strong external driving force that matches one of these frequencies, this condition is referred to ast a. Hazard c. Resonance b. Implosion d._ Interference These type of waves do not require a medium for travel: a. Seismic waves c. Sound waves >, Microwaves dd. Water waves This specific thermodynamic property always increases when an irreversible process occurs in a closed system: a. Volume ©. Entropy b. Pressure d. Energy ‘The electrical resistivity of brass (a Cu-Zn alloy), compared to pure Cu is: a. Lower by one order of magnitude c. Higher by one order of magnitude b. Equal d. Lower by two orders of magnitude The ideal gas equation PV=nkT is modified to (P-+an7/V*)(V-nb) = nRT to describe the behavior of a real gas. The latter equation is named after: a, Edwin Aldrin c. Emest Rutherford b, Johannes van der Waals 4d. Johannes kepler VLDL's (very low density lipoproteins) are synthesized in a. Heart c b. lungs d Bernoulli's equation in fluid flow is based on a. First law of thermodynamics . b. Ficks second law of diffusion d._ conservation of energy FACS with reference to flow cytometry is a. Fluorescence activated cell sorting c. Fluoride activated cell sorting b, Fluorescence activated cell suspension d. Fluoride activated cell suspension HEMA, one of the most common biomaterial monomer is a. 2-hydroxy ethane molybdenum acetic acid cc. 2-hydroxyethyl methacrylate b. 2-hydroxy ethane manganese acetone d. None of these Pharmacokinetics of a drug is impacted by a. Absorption of drug ¢. Distribution of drug b, Metabolism of drug d. Allof these ‘As per Beer-lambert law, if A is absorbance, a is absorptivity or extinction coefficient, bis length of the beam in absorbing medium, and c is the concentration of the absorbing species a, A=abe c. A=bela b. A=able d. cab Page 5 of 1052 53 54 55 56 357 58 59 60 61 Phospholipids in biomembranes are a. Only Hydrophilic ©. Only Hydrophobic b. Amphipathic (both hydrophilic and hydrophobic d. None of these part) With reference to protein structures, Alpha-helix is a type of a. Primary structure ¢. Tertiary structure b. Secondary structure 4. Quaternary structure ‘As per le chatelier’s principle, for an exothermic reaction, increasing the temperature a. would lead to equilibrium shift towards reactants ¢. would have no impact (towards left) d. None of these b. would lead to equilibrium shift towards produets (towards right) Which immunoglobin can significantly cross placenta a. Iga ©. IgE b. ID d. IgG Which of the following is a gram-positive bacterium? a. Yersinia pestis c. Staphylococcus aureus b. Klebsiella pneumonia d. Chlamydia trachomati For a HPLC (High performance liquid chromatography), which of the following are false a, Sample is introduced along witha _c, Detector connected to column outlet mobile phase monitors each eluting compound from the b, Separation is achieved by column different moving speeds of each 4. Allare true compound Ratio of inertia forces to viscous force is called a, Froude's number c. weber number b, Reynolds number d. Euler number Biological evaluation and screening test that uses tissue cells in vitro to observe the cell growth, reproduction and morphological effects by medical devices is called as a. Cytotoxicity test sensitization test b. Hemocompatibility test skin irritation test For a normal distribution of data, a, 90% of data falls within 2 standard ¢. 99.7% of data falls within 2 standard deviations of the mean deviations of the mean b. 68% of data falls within 2 standard d. 95% of data falls within 2 standard deviations of the mean deviations of the mean Genome of COVID-19 causing virus genome is made of a, ssDNA c. ssRNA b. dsDNA d. dsRNA Page 6 of 1062 63 65 67 68 69 70 1 2 2B PPE means? a. Public private enterprise ©. Public protection entity b. Personal protective equipment 4. Personal protection enterprise In a certain code "DIVISION" is written as "DVISOIN", then how is "STATES" written? a. SATETS c. SAETTS b. SATTES d. STTAES Aroom has 10 doors. In how many ways one can enter through a door and exit through a different door? a 9 ec. 100 b. 10 d 90 In this "see and tell" sequence, what is the next number?: 1, 11, 21, 1211, 111221, a. 312211 ©. 1112222 b. 1112221 4. 112131 At extreme depths in the sea (beyond 170 m depth), divers experience hallucinations, dizziness, tremors etc because of - a. hyperventilation ¢. high-pressure neurological syndrome b. decompression sickness d. diving reflex Which is the primary stress hormone a) cortisol ©) adrenaline b) aldosterone 4) noradrenaline Name a plastic-degrading systems a, PETase c. MHETase b. ACE 4. both 1 &3 SARS-CoV-2 spike protein is a a. surface glycoprotein ¢. nucleocapsid protein b. small envelope protein d. matrix protein Covishield is - type of vaccine a, whole virion inactivated , mRNA b. recombinant, replication-deficient adenovirus vector 4, DNA encoding Spike protein Paralympic Games 2020 was conducted at a. Abu Dhabi c. Rio b. Tokyo d. Beijing Nobel Prize for Physics in 2020 was awarded for the discovery of a. cosmology c. theory for Black hole formation b. optical tweezers 4. discovery in alloys The theory of relativity is presented by which scientist a. Albert Einstein c. Stephen Hawking b. Isaac Newton d. Marie Curie Page 7 of 1074 15 16 1 8 799 80 81 82 83 84 85 Total number of elements in the Periodic table a 112 ce. 11S b. 18 d. 127 Which one is the purest form of carbon a. coat c. graphite b. diamond d. iron ‘The membrane proteins can span across the lipid bilayer strictly due to the presence of a. alpha helices c. antiparallel beta sheet b. parallel beta sheet d. zine finger domain To detect specific macromolecule or structure by electron microscopy, the frequently used procedure is to couple the antibody with a. Osmium tetraoxide c. Gold Particle b. Alexa 568 d Cys The inner cell mass of mammalian embryo in the blastocyst stage are a. totipotent c. multipotent b. pluripotent d._unipotent Which of the following number is a prime number a 121 ©. 183 b. 163 4. 1020 The enzyme Rennin is secreted in which among the following parts of the Alimentary Canal? a. Mouth c. Pancreas b. Duodenum d. Stomach Both prokaryotic as well as eukaryotic cells have a, Lysosomes ¢. Ribosomes b. Mitochondria d. Golgi Bodies Which one of the following is does not involve in maturation of red blood cells a, pyridoxine ¢. vitamin B12 b. tocopherol d. folic acid Migration of individual cells from the surface into the embryo’s interior is termed as a, ingression c. invagination b. involution d. delamination Which of the following hormone is detected by pregnancy kits? a, Estrogen ¢. Human Chorionic Gonadotropin b. Progesterone d. Lutinizing Hormone Five persons A, B, C, D, and E are sitting in a row, C in the middle of the group and D is at an extreme end. There are at least two persons between B and E. Which of the following statements is incorrect? a. Ecan be on extreme left b. Ais always a neighbour of B or D c. Accannot be on extreme left d. Ean be on extreme right Page 8 of 1086 87 88 89 1 93 94 95 Each pixel in a liquid crystal display (LCD) television is composed of 3 sub-pixels that can transmit red, green and blue colours because a. White light is made of three primary c. The human retina contains only three colours viz red, green, blue types of colour-sensitive cells b. Liquid crystals can only filter these primary d, These colours are the most pleasing to the colours human eye. ‘The Nobel prize in physiology or medicine 2020 was shared by Harvey J. Alter, Michael Houghton and Charles M. Rice for a. The development of a method for c. The discoveries of how cells sense and genome editing adapt to oxygen availability b. The discovery of Hepatitis C virus d._ The discoveries of molecular mechanisms controlling the circadian rhythm The first WHO recognized outbreak of Nipah virus was reported in a. Malaysia c. Singapore b. Bangladesh d. India ‘Who among the following is a climate campaigner? a, Verghese Kurien ¢. Greta Thunberg b. Malala Yousafzai d. Michelle Obama The only active volcano of India is located at a, Gujarat c. Maharashtra b. Haryana 4, Andaman & Nicobar Islands EJOT, DHLP, CFIL, ? a, BHLM ©. DGKL b. BDFH d. DEW ‘Aman walks 30 meters towards south. Then turning to his right, he walks 30 meters. Then 1¢ walks 20 meters. Again, he turns to his left and walks 30 meters. How far is he turning from his initial position? a. 110 meters c. 60 meters b. 80 meters d. 50 meters The ratio of the ages of a man and his wife is 4:3. After 4 years, this ratio will be 9:7. If at the time of marriage, the ratio was 5:3, then how many years ago were they married? a, 1S years c. 10years b. 12 years 4. 8 years The first track and field athlete to win a gold medal for India at the Olympics a. AbhinavBindra ¢. Neeraj Chopra b. PV Sindhu d. Nirav Modi By the end of next month my grandmother _in the same house for more than 80 years a. will have been living. _will have lived b. will live 4. will be living Page 9 of 1096 97 98 Leaf of a plant appears green in daylight. If this plant were observed in red light, what colour would its leaf appear ? a. green ©. red b._black-brown d. blue ‘Twenty one liters of milk in a tank is to be divided into three equal parts using only5, 8 and 12 liters capacity cans. The minimum number of transfers needed to achieve this is... a 3 «5 b 4 a7 How many times starting at 1:00 pm would the minute and hour hands of a clock make an angle of 40 Degree with each other in the next 360 minutes? a 6 e b 7 d. 12 Which is not an essential amino acid a. proline c. valine b. methionine d.tysine 100 Which Indian city has the Drink-from-Tap facility for the first time in India? a. Bangalore ¢. Trivandrum b. Srinagar a. Puri Page 10 of 10‘Academic Session - January 2022 ‘Answer Key: PhD Bioengineering Tye a} qu 7 e 81 AL 61 ZT) ey Ble itl al . Tye a] d icite ole Z +) o mT, z d 44 64 84 * . : 45, e 65 y 85 6 d & 461 c¢ é wl 86 TT. : rae ae 7 Ta ale cates ale #8 eae a9} ¢ erie te Tw] a 30 |< aaa al 30 wale a | si} a n| ® a ae 2|¢ baal fd mile 92 ae 33 | ere ce al’ 93 we 34 a ad i 4 94 es 35 | *. Ssi4 5 95 tee Ralet 36 | ¢ bee 96 ee nl sa\a ane 7 ya as | # 38 | b ale 98 7 wo |? 9] a i ‘ 99 Tb sede oo} 4 ce 100