Rheumatoid Hand

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Rheumatoid Hand

Epidemiology

-Rheumatoid Arthritis affects 1% of the US population. RA is more common in


women.

-Etiology of RA is unknown, but it is thought to be multifactorial with both


genetic (particularly HLA DR4) and environmental factors playing a role.

Pathophysiology

-RA is a common inflammatory arthritis resulting from a T-cell driven


autoimmune process, this results in an inflammatory response within
synovium with upregulation of TNF-a and IL-1, causes synovial hypertrophy
(pannus) that erodes cartilage, bone, and soft tissue.

Diagnosis

– 4 of 7:

1. morning joint stiffness

2. soft tissue swelling of 3+ joints

3. symmetrical joint involvement

4. involvement of MP, PIP, or wrist joints

5. rheumatoid nodules

6. seropositive RF

7. radiographic findings

Labs

– RF positive in 70-80%
– Anticitrullinated peptide antibody (anti CCP) has high specificity for RA

Medical Management: This is managed by rheumatologists.

– Medical management has improved significantly in recent years with


advent of biologics, may see LESS rheumatoid hand in your clinic but
the cases you do see are likely to be more severe
– Treatment aims for the containment of chronic inflammation as well as
structural protection for the joints.

There are 3 general classes of medications.


NSAIDS: treatment only and does not alter course of disease or prevent joint
destruction. (ex: ibuprofen)

Corticosteroids: prednisone and methylprednisone used to reduce


inflammation and regulate immune system activity when NSAIDS are no
longer able to control symptoms or during flares.

DMARDS (disease modifying antirheumatic drugs): used after a


diagnosis of RA to reduce structural damage early on. These drugs have anti-
inflammatory effects along with structurally modifying properties. This is
used for long lasting control of RA and have two types: nonbiologic (IE
methotrexate) and biologic.

Holding medications for surgery:

– Methotrexate and other DMARDS – typically are continued, but should


be discussed with rheumatology
– Steroids – continued at normal preoperative dosage, and may require a
stress dose at time of surgery if taking 5-10mg/day or more
– Biologics – May need to be held for 2-4wks before and after surgery

Imaging- typically radiographic examination. This will exhibit:

– Joint space narrowing


– Marginal erosions
– Characteristic deformities- ulnar translocation of carpus, ulnar
deviation of fingers.

Surgical Intervention:

– Surgery recommended after failure of conservative management with


6-12 months of medical management

Principles:

– Principal indication for surgery is PAIN, and function is secondary. Many


patients have compensated for these deformities and minimal
functional complaints
– Start with PROXIMAL procedures before distal – for example you would
address a wrist deformity prior to the digits as the wrist deformity likely
exacerbates the digital deformity
– Presenting Hand Deformities: Wrist deformities, metacarpal phalangeal
joint deformities, Tendon Involvement, and Finger Deformities.
Remember, a stable wrist sets the foundation for future reconstruction
of the hand!
Wrist: The wrist is the most commonly affected joint in RA.

– Synovitis of the wrist joint weakens bot the intrinsic and extrinsic wrist
ligaments which leads to deformities such as ulnar translocation of the
carpus, DRUJ disruption and ulnar dislocation, ECU tendon attenuation
– This results in the “Caput ulnae” deformity (*ulnar head dislocates
dorsally) results in DRUJ incongruity and impaction of the distal ulna on
the carpus which can lead to arthric changes and PAIN

Surgical Correction: This can be considered prophylactic or corrective.

Prophylactic: RL (radiolunate) arthrodesis procedure (only if midcarpal joint


is free from disease)- stabilizes wrist and allows better motion through the
midcarpal joint

(Corrective) DRUJ: Darrach and Sauve-Kapandji.

– The Darrach procedure involves resection of distal ulna. This provides


pain relief from DRUJ and distal ulna impingement on the carpus.
– SK: Ostectomy of the proximal ulna with FUSION of the DRUJ, fuses
distal radioulnar joint in combination with proximal ulna ostectomy to
provide stable rotary function. This preserved ulnar head gives support
to the carpus and prevents ulnar translocation.
– Finally debilitating pain can be corrected with wrist arthrodesis vs
arthroplasty.

Limited arthrodesis can slow progression of deformities.

Total wrist fusion can achieve stable wrist and decrease pain. This is used
with a combination of pins or plates.

– If bilateral wrists are involved- it is recommended for arthroplasty of


dominant wrist and arthrodesis of nondominant wrist in neutral to 15
degrees extension.

MCP Joints: typical deformity in RA is volar subluxation of proximal


phalanges and ulnar deviation of the fingers and this is secondary to attrition
of the RADIAL SAGGITAL BAND

Classic finding – these patients will not be able to actively extend digits at
MCP on their own but if you passively extend them they are able to hold
MCPS in extension. This limitation is due to this radial saggital band rupture
and subluxation of the extensor mechanism. When they are passively
corrected this centralizes the extensor mechanism and they are then able to
hold in extension. — ASKED PREVIOUSLY on exam
Treatment: arthrodesis vs arthroplasty. Arthrodesis rarely performed
because of arc of motion of the fingers is initiated at the MCP joint

One way to address this MCP deformity with a “cross intrinsic transfer”
where the ulnar lateral band to a digit is divided and transferred to adjacent
digit radial saggital band, alternatively could preform only a “intrinsic
release”

Another common finding in RA is Tendon Rupture:

2 reasons for tendon rupture

1) abrasion of the tendon over bony prominences (eroded distal ulna or distal
pole of scaphoid)

2) weakening of the tendon by synovial invasion.

Tendon problems include: Trigger finger due to focal tenosynovitis or


rheumatoid nodule within sheath/tendon;

Don’t perform A1 pulley release, surgically debride tenosynovitis and nodules

Flexor Tendon Ruptures -FPL rupture is the most common, secondary to


wear against volar scaphoid osteophyte, called Mannerfelt lesion;

Surgery includes removing osteophyte at level of scaphoid and index FDS


transfer to FPL or arthrodesis of thumb IP joint

Extensor tendon ruptures- due to extensor tenosynovitis, attrition over


sharp edges caused by DRUJ and radiocarpal arthritis

– Extensor tendon involvement typically progress from ulnar to radial.


Small finger followed by ring, long, index extensors (Vaughn-Jackson
syndrome)
– Diagnosis of small finger EDQ rupture comes from testing EDQ
independent of EDC (extend small finger while other fingers flexed).
– Definitive operative management includes Darrach and excision of
synovial tissue over extensor tendon.
– Additionally, EPL rupture can occur- typically reconstructed with EIP
– Other extensor deficits:

If patient is unable to actively extend the digits, but extensor tenodesis is


intact, an additional cause may be PIN Syndrome due to compression of this
nerve around the elbow at the radiocapitellar joint

RA Finger Deformities: Boutonniere versus Swan-Neck


– Boutonniere deformity: PIP flexion, DIP hyperextension, pathology
always originates at PIP joint patients present mainly an aesthetic
concern. Typically starts as elongation of the central slip. The lateral
bands sublux below the axis of rotation, resulting in shortening of the
retinacular ligaments. This causes flexion of the PIP and extension of
the DIP (from tightening of the lateral bands).
– Two different deformities (flexible or fixed). For flexible deformities may
use soft tissue reconstruction including joint synovectomy, tightening
of the stretched central tendon, and dorsal fixation of the lateral
bands.

Arthrodesis is typically favored in fixed boutonniere given that arthroplasty


requires excision and removal of collateral ligaments thus destabilizing the
joint.

– Swan neck deformity: PIP hyperextension, DIP flexion

Pathology can originate at several different levels

DIP: erosion of terminal tendon (mallet type finger)

PIP: stretching of volar plate or rupture of FDS insertion resulting in PIP


hyperextension

MCP: subluxation of the joint and extensor tendon mechanism can result in
ulnar intrinsic tendon tightness

– Surgical correction of swan neck depends on its origin and if it is


flexible or fixed.
– Flexible PIP joint can be treated with splinting
– Limited PIP joint flexion with MCP extended (intrinsic tightness) – Tx
with splint +/- intrinsic release
– If joint is fixed then options include arthroplasty or arthrodesis

Thumb Deformities:

– Most common deformity is boutonniere (MCP flexed IP extended) or


more rare swan neck deformity

Treatments:

Boutonniere- MCP fusion

Swann- Neck CMC arthroplasty or arthrodesis

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