6300 SERIES Sds
6300 SERIES Sds
6300 SERIES Sds
6300 SERIES
1. PRODUCT AND COMPANY IDENTIFICATION
2. HAZARDS IDENTIFICATION
PICTOGRAMS
3. COMPOSITION/INFORMATION ON INGREDIENTS
Xylene 1% - 5% 1330-20-7
Phenylethane 1% - 5% 100-41-4
EYES CONTACT : Flush with large quantities of water for 15 to 30 minutes. Remove contact lenses. Keep eyes wide open
while rising. If eye irritation persists: Get medical attention.
SKIN CONTACT : Wash exposed area with mild soap and water for 15 to 30 minutes. Remove contaminated clothing.
Repeated exposure may cause dryness or cracking.
INGESTION : Rinse mouth. Do NOT induce vomiting. Keep victim warm and seek immediate attention.
INHALATION : Remove to fresh air and keep in a position comfortable to breath. Call a doctor/physician if you feel
unwell. Get medical attention.
Most important symptoms and effects, both acute and delayed. Symptoms/injuries: Eye irritation
Symptoms/injuries after inhalation: May cause drowsiness or dizziness.
Symptoms/injuries after eye contact: Cause serious eye irritation.
Symptoms/injuries after ingestion: Ingestion may cause nausea, vomiting and diarrhea.
Indication of any immediate medical attention and special treatment needed.
If medical advise is needed, have product container or label on hand.
SUITABLE EXTINGUISHING MEDIA : In the event of a fire, use specifically suitable extinguishing agents. Suitable
extinguishing media: Foam, alcohol resistant foam, CO2, water fog. Unsuitable extinguishing media: Do not use heavy
water stream. A heavy water stream may spread burning liquid.
FIRE FIGHTING PROCEDURE : Firefighting instructions: Use water spray or fog for cooling exposed containers. Exercise
caution when fighting any chemical fire. Prevent fire-fighting water from entering the environment.
Protection during firefighting: Firefighters should wear full protective gear. Do not enter fire area without proper protective
equipment, including self-contained breathing apparatus with full face piece operated in pressure demand or other positive
pressure modes.
UNUSUAL FIRE AND EXPLOSION HAZARD : Fire hazard: Highly flammable/liquid or vapor.
Explosive hazard: May form flammable/explosive vapor-air mixture.
ENVIROMENTAL PRECAUTIONS :
Prevent entry to sewers and public waters.
PRECAUTIONS FOR SAFE HANDLING : Additional hazards when processed: Handle empty containers with care because
residual vapors are flammable.
Precautions for safe handling: Wash hands and other exposed areas with mild soap and water before eating, drinking or
smoking and when you are leaving work. Provide good ventilation in process area to prevent formation of vapor. No
smoking. Use only non-sparking tools. Use outdoors or in a well ventilated area. Avoid breathing fume, vapors.
Hygiene measures: Wash Skin thoroughly after handling.
CONDITIONS FOR SAFE STORAGE, INCLUDING INCOMPATIBILITIES : Storage conditions: Store in a dry, cool and
well-ventilated place away from : Heat sources. Direct sunlight.
BENZENE(71-43-2)
USA ACGIH ACGIH STEL 2.5 ppm
USA ACGIH ACGIH TWA 0.5 ppm
USA OSHA OSHA CARC PEL 1 ppm
USA OSHA OSHA CARC STEL 5 ppm
USA OSHA OSHA CIEL (Table Z-1-A) 5 ppm
USA OSHA OSHA STEL 5 ppm
USA OSHA OSHA TWA (Table Z-1-A) 1 ppm
Carbon Black(1333-86-4)
USA ACGIH ACGIH TLV (mg/m3) 3.0 mg/m3
USA OSHA OSHA PEL (mg/m3) 3.5 mg/m3
n-Butyl Acetate(123-86-4)
USA ACGIH ACGIH STEL 200 ppm
USA ACGIH ACGIH TWA 150 ppm
USA OSHA OSHA PEL (Table Z-1) 150 ppm, 710 mg/m3
n-Methyl-2-pyrrolidone(872-50-4)
USA ACGIH ACGIH PEL N/E
USA OSHA OSHA TWA N/E
P.M. Acetate(108-65-6)
USA AIHA AIAH (WEEL) TWA 50 ppm
Phenylethane(100-41-4)
USA ACGIH ACGIH STEL 125 ppm
USA ACGIH ACGIH TWA 20 ppm
USA NIOSH NIOSH REL 100 ppm, 435 mg/m3
USA NIOSH NIOSH REL (ST) 125 ppm, 545 mg/m3
USA OSHA OSHA STEL 125 ppm, 545 mg/m3
USA OSHA OSHA TWA (Table Z-1) 100 ppm, 435 mg/m3
Titanium Dioxide(13463-67-7)
PEl (Permissible Exposure Limit) OSHA TWA 15 mg/m3
TLV ACGIH TWA 10 mg/m3
Toluene(108-88-3)
USA ACGIH ACGIH TWA 20 ppm
USA NIOSH NIOSH REL (ST) 150 ppm, 560 mg/m3
USA NIOSH NIOSH REL TWA 100 ppm, 375 mg/m3
USA OSHA OSHA STEL (PO) 150 ppm, 560 mg/m3
USA OSHA OSHA TWA (PO) 100 ppm, 375 ppm
USA OSHA OSHA TWA (Table Z-2) 200 ppm
Xylene(1330-20-7)
USA ACGIH ACGIH STEL 150 ppm
USA ACGIH ACGIH TWA 100 ppm
USA OSHA OSHA TWA (Table Z-1) 100 PPM, 435 mg/m3
RESPIRATORY PROTECTION : If TLV of the product or any component is exceeded, a NIOSH approved dust respirator is
advised in absence of environmental control. OSHA Regulations also permit other NIOSH dust respirators under specified
conditions. (See your Safety Equipment Supplier) Engineering or administrative controls should be implemented to reduce
exposure.
HAND PROTECTION REMARKS : The suitability for a specific workplace should be discussed with the producers of the
protective gloves.
SKIN AND BODY PROTECTION : Wear impervious clothing. Choose body protection according to the amount and
concentration of the dangerous substance at the work place.
WORK HYGIENIC PRACTICES: When using do not eat or drink. When using do not smoke. Wash hands before breaks
and at the end of workday.
HAZARDOUS DECOMPOSITION PRODUCTS: Carbon dioxide (CO2), carbon monoxide (CO), oxides of nitrogen (NOx),
dense black smoke.
Amorphous Silica(7631-86-9)
Additional toxiclogical The product is not subject to classification according to internally approved calculation methods
information for preparations: When used and handled according to specifications, the product does not have
any harmful effects according to our experience and information provided to us.
Irritant of skin Not irritating (rabbit) (OCED 404)
Irritation of eyes Not irritating (rabbit) (OCED 405)
LC0 - Inhalation >140->2000 mg/m3 / 4 h (Rat) (OCED 403)
LD50 - Dermal - Rabbit >5000 mg/kg (Rabbit)
LD50 - Oral - Rat >5000 mg/kg (Rat) (OECD 401)
Other information - => 1340 mg/kg/day
Oral
Sensitization Not sensitization (guinea pig) (OCED 406)
BENZENE(71-43-2)
Aspiration toxicity May be fatal if swallowed and enters airways. Substances known to cause human aspiration
toxicity hazards or to be regarded as if they cause human aspiration toxicity hazard.
Carcinogenicity Species: rat Sex: female Dose: 0, 25, 50, 250 mg/kg Exposure time: 103 wks Number of
exposures: daily, 5 days/week Test substance: yes Remarks: zymbal gland carcinomas,
squamous cell papillomas Species: rat Sex: male Dose: 0, 50, 100, 200 mg/kg Exposure time:
103 wks Number of exposures: daily, 5 days/week Test substance: yes Remarks: zymbal gland
carcinomas, squamous cell papillomas Species: mouse Sex: male and female Dose: 25, 50, 100
mg/kg Exposure time: 103 wks Number of exposures: daily, 5 days/week Test substance: yes
Remarks: Clear evidence of multiple organ carcinogenicity.
CMR effects Carcinogenicity: Human carcinogen. Mutagenicity: In vivo tests showed mutagenic effects
Teratogenicity: Did not show teratogenic effects in animal experiments. Reproductive toxicity:
Animal testing did not show any effects on fertility.
Eye irritation May cause irreversible eye damage.
Further information Chronic Health Hazard. Solvents may degrease the skin.
LC50 Dermal 44.5 mg/l Exposure time: 4 h Species: rat Sex: Not Specified Test atmosphere: vapor
LD50 > 8,260 mg/kg Species: rabbit
LD50 Oral > 2,000 mg/kg Species: rat Sex: female
Repeated dose toxicity Species: rat, female Sex: female. Application Route: oral gavage Dose: 0, 25, 50, 100 mg/kg
Exposure time: 103 wk Number of exposures: 5 d/wk NOEL: < 25 mg/kg Lowest observable
effect level: 25 mg/kg Species: rat, male Sex: male Application Route: oral gavage Dose: 0, 50,
100, 200 mg/kg Exposure time: 103 wk Number of exposures: 5 d/wk NOEL: < 50 mg/kg
Lowest observable effect level: 50 mg/kg Species: mouse Application Route: oral gavage Dose:
0, 25, 50,100 mg/kg Exposure time: 103 wk NOEL: < 25 mg/kg
Sensitization Did not cause sensitization on laboratory animals.
Skin irritation May cause skin irritation in susceptible persons.
Carbon Black(1333-86-4)
ACGIH ACGIH The American Conference of Governmental Industrial Hygienists classifies carbon black as
A4, Not Classifiable as a Human Carcinogen.
Carcinogenicity GHS- Not a hazardous substance or preparation according to the Global Harmonized System
Classification (GHS).
Human Epidemiology Results of epidemiological studies of carbon black production workers suggest that cumulative
exposure to carbon black may result in small decrements in lung function, as measured by FEV1.
A recent U.S. respiratory morbidity study suggested a 27 mL decline in FEV1 from a 1 mg/m3
(inhalable fraction) exposure over a 40-year period. An older European investigation suggested
an exposure to 1 mg/m3 (inhalable fraction) of carbon black over a 40-year working-lifetime will
result in a 48 mL decline in FEV1. In contrast, normal age related decline over a similar period of
time would be approximately 1200 ml. The relationship between symptoms and exposure to
carbon black is less clear. In the U.S. study, 9% of the highest exposure group (in contrast to
5% of the unexposed group) reported symptoms consistent with chronic bronchitis. In the
European study, methodological limitations in the administration of the questionnaire limit the
drawing of definitive conclusions about symptoms.
Human Epidemiology - Since this IARC evaluation of carbon black, Sorahan and Harrington 16) re-analyzed the UK
cont study data using an alternative exposure hypothesis and found a positive association with
carbon black exposure in two of the five plants. The same exposure hypothesis was applied by
Morfeld and McCunney 17-18) to the German cohort; in contrast, they found no association
between carbon black exposure and lung cancer risk and, thus, no support for the alternative
exposure hypothesis used by Sorahan and Harrington 16).
Human Epidemiology - Morfeld and McCunney 19) applied a Bayesian approach to unravel the role of uncontrolled
cont. confounders and identified smoking and prior exposure to occupational carcinogens received
before being hired in the carbon black industry as main causes of the observed lung cancer
excess risk. Overall, as a result of these detailed investigations, no causative link between
carbon black exposure and cancer risk in humans has been demonstrated. This view is
consistent with the IARC evaluation in 2006. Several epidemiological and clinical studies of
workers in the carbon black production industries show no evidence of clinically significant
adverse health effects due to occupational exposure to carbon black. No dose response
relationship was observed in workers exposed to carbon black.
Human Epidemiology - This study, however, indicated a link between carbon black and small opacities on chest films,
cont. with negligible effects on lung function. A study on carbon black production workers in the UK
10) found an increased risk of lung cancer in two of the five plants studied; however, the
increase was not related to the dose of carbon black. Thus, the authors did not consider the
increased risk in lung cancer to be due to carbon black exposure. A German study of carbon
black workers at one plant 11-14) found a similar increase in lung cancer risk but, like the 2001
UK study 10), found no association with carbon black exposure. In contrast, a large US study
15) of 18 plants showed a reduction in lung cancer risk in carbon black production workers.
Based upon these studies, the February 2006 Working Group at IARC concluded that the human
evidence for carcinogenicity was inadequate 1) .l
IARC IARC In 1995 IARC concluded, "There is inadequate evidence in humans for the carcinogenicity
of carbon black." Based on rat inhalation studies IARC concluded that there is, "sufficient
evidence in experimental animals for the carcinogenicity of carbon black," IARC's overall
evaluation was that, "Carbon black is possibly carcinogenic to humans (Group 2B)". This
conclusion was based on IARC's guidelines, which require such a classification if one species
exhibits carcinogenicity in two or more studies. IARC performed another review in 2006, and
again classified carbon black as possibly carcinogenic to humans (Group 2B). In its 1987 review
IARC concluded, "There is sufficient evidence in experimental animals for the carcinogenicity of
carbon black extracts." Carbon black extracts are classified as, possibly carcinogenic to humans
(Group 2B).
LD50 (Rat) >8000 mg/kg
Mutagenic Effects and In an experimental investigation, mutational changes in the hprt gene were reported in alveolar
Germ Cell Mutagenicity epithelial cells in the rat following inhalation exposure to carbon black. This observation is
believed to be rat specific and a consequence of "lung overload" which led to chronic
inflammation and release of genotoxic oxygen species. This mechanism is considered to be a
secondary genotoxic effect and thus, carbon black itself would not be considered to be
mutagenic. Carbon black is not suitable to be tested in bacterial (Ames test) and other in vitro
systems because of its insolubility in aqueous solutions. When tested, however, results for
carbon black showed no mutagenic effects. Organic solvent extracts of carbon black can,
however, contain traces of polycyclic aromatic hydrocarbons (PAHs). A study to examine the
bioavailability of these PAHs showed that PAHs are very tightly bound to carbon black and not
bioavailable.
NIOSH NIOSH The U.S. National Institute of Occupational Safety and Health (NIOSH) 1978 criteria
document on carbon black recommends that only carbon blacks with PAH contaminant levels
greater than 0.1% require the measurement of PAHs in air. As some PAHs are possible human
carcinogens, NIOSH recommends an exposure limit of 0.1 mg/m3 for PAHs in air, measured as
the cyclohexane-extractable fraction.
NTP NTP Carbon black is not designated a carcinogen by the U.S. National Toxicology Program (NTP),
the U.S. Occupational Safety and Health Administration (OSHA) or the European Union (EU).
Reproductive and No experimental studies on effects of carbon black on fertility and reproduction have been
Teratogenic Effects located. However, based on toxicokinetic data, carbon black is deposited in the lungs and based
on its specific physicochemical properties (insolubility, low absorption potential), it is not likely to
distribute in the body to reach reproductive organs, embryo and/or foetus under in vivo
conditions. Therefore, no adverse effects of carbon black to fertility/reproduction or to fetal
development are expected. No effects have been reported in long-term animal studies.
Sensitization No animal data is available. No cases in humans have been reported.
STOT- repeated Therefore, no STOT, Repeated exposure classification is made.
exposure
STOT- single exposure Inhalation studies with the rat showed lung effects (see Section 11.2 and 11.3), these effects
are believed to be the effects of "lung overload" 1 and these effects are believed to be specific to
the species. In addition, the European CLP Regulation states that no classification is necessary if
the mechanism is not relevant to humans. 4) Also, the CLP Guidance on classification and
labeling states that the "lung overload" mechanism is not relevant to humans. 4) Therefore, no
STOT, Repeated Exposure classification is made
n-Butyl Acetate(123-86-4)
Aspiration hazard No data available.
Carcinogenicity No data available.
Inhalation No data available.
LD-50 Dermal - > 16ml/kg
(Rabbit)
LD-50 Oral - (Rat) 14,130 mg/kg
Mutagenicity In vitro: No data available. In vivo: No data available.
Other adverse effects: No data available.
Repeated dose toxicity No data available.
Reproductive toxicity No data available.
Respiratory or skin Skin Sensitization:, (Guinea Pig) - non-sensitizing.
sensitization
Serious eye (Rabbit, 24 h): none
damage/eye irritation
Skin (Rabbit, 24 h): none
corrosion/irritation
Specific target organ No data available.
toxicity - repeated
exposure
Specific target organ Narcotic effect.
toxicity - single
exposure
n-Methyl-2-pyrrolidone(872-50-4)
Aspiration Hazard Not Applicable.
Assessment other Assessment of STOT single: Causes temporary irritation of the respiratory tract. Irritation /
acute effects corrosion Assessment of irritating effects: Eye contact causes irritation. Skin contact causes
irritation. Causes temporary irritation of the respiratory tract. EU-classification Skin Species:
rabbit Result: Slightly irritating. Method: Draize test Literature data. The European Union (EU)
has classified this substance with 'Irritating to skin' (R38). Eye Species: rabbit Result: Irritant.
Method: Draize test Literature data. Sensitization Assessment of sensitization: Skin sensitizing
effects were not observed in animal studies. Mouse Local Lymph Node Assay (LLNA) Species:
mouse Result: Non-sensitizing. Method: OECD Guideline 429 The product has not been tested.
The statement has been derived from substances/products of a similar structure or composition.
Carcinogenicity Assessment of carcinogenicity: In long-term animal studies in which the substance was given by
inhalation, a carcinogenic effect was not observed. In long-term studies in rats in which the
substance was given by feed, a carcinogenic effect was not observed. In long-term studies in
rodents exposed to high doses, a tumorigenic effect was found; however, these results are
thought to be due to a rodent-specific liver effect that is not relevant to humans. The whole of
the information assessable provides no indication of a carcinogenic effect.
Genetic toxicity Assessment of mutagenicity: The substance was not mutagenic in bacteria. No mutagenic effect
was found in various tests with mammalian cell culture and mammals.
LC50 Inhalation - Rat > 5.1 mg/l (OECD Guideline 403) Exposure time: 4 h An aerosol was tested. Limit concentration
test only (LIMIT test). No mortality was observed.
LD50 Dermal - Rat 5,000 mg/m3; Species: rat (male/female) Value: > 5,000 mg/kg (OECD Guideline 402)
Literature data.
LD50 Oral - Rat 4,150 mg/kg (OECD Guideline 401) Literature data.
Repeated dose toxicity Assessment of repeated dose toxicity: After repeated exposure the prominent effect is local
irritation. The substance may cause damage to the testes after repeated inhalation of high
doses. Experiment
Reproductive toxicity Assessment of reproduction toxicity: As shown in animal studies, the product may cause damage
to the testes after repeated high exposures that cause other toxic effects.
Symptoms of Exposure Medical conditions aggravated by overexposure Data available do not indicate that there are
medical conditions that are generally recognized as being aggravated by exposure to this
substance/product.
Teragenicity Assessment of teratogenicity: The substance caused malformations/developmental toxicity in
laboratory animals.
P.M. Acetate(108-65-6)
Aspiration hazard No data available.
Carcinogenicity No data available.
LC50 - Inhalation Rat >4345 ppm (Rat, 6 h)
LD50 - Dermal - Rabbit >5000 mg/kg
LD50 - Oral - Rat 6,190 mg/kg
Mutagenicity In vitro: No data available. In vivo: No data available.
Other adverse effects No data available.
Repeated dose toxicity No data available.
Reproductive toxicity. No data available.
Respiratory or skin Skin Sensitization:, (Guinea Pig) - non-sensitizing
sensitization
Serious eye (Rabbit): very slight
damage/eye irritation
Skin Specified substance(s) 2-methoxy-1-methylethyl acetate (Rabbit, 4 h): none (Rabbit, 24 h):
corrosion/irritation none.
Specific target organ No data available.
toxicity - repeated
exposure
Specific target organ No data available.
toxicity - single
exposure
Phenylethane(100-41-4)
Aspiration toxicity May be fatal if swallowed and enters airways.
Carcinogenicity Species: mouse, (male and female) Application Route: Inhalation Exposure time: 103 wk
Activity duration: 6 h Dose: 0, 75, 250, 750 ppm Frequency of Treatment: 5 days/week NOAEL:
250 ppm Method: OECD Test Guideline 453 Result: evidence of carcinogenic activity Symptoms:
increased incidences of alveolar/bronchiolar neoplasm’s, increase incidence of hepatocellular
carcinomas GLP: yes Carcinogenicity - Assessment : Carcinogenicity classification not possible
from current data.
Germ cell mutagenicity Genotoxicity in vitro, Test Type: Chromosome aberration test in vitro Test species: Chinese
hamster ovary (CHO) Metabolic activation: with and without metabolic activation Method: OECD
Test Guideline 473 Result: negative GLP: no : Test Type: Mammalian cell gene mutation assay
Test species: mouse lymphoma cells Metabolic activation: with and without metabolic activation
Method : OECD Test Guideline 476 Result: negative GLP: yes Genotoxicity in vivo : Test Type:
In vivo micronucleus test Test species: mouse (male) Application Route: Oral Method: OECD
Test Guideline 474 Result: negative GLP: yes Test Type: DNA damage and/or repair Test
species: mouse (male and female)Application Route: Inhalation Method: OECD Test Guideline
486 Result: negative GLP: yes Germ cell mutagenicity Assessment : In vivo tests did not show
mutagenic effects
LC50 (Mouse, Male) 10 mg/l Assessment: The component/mixture is moderately toxic after short term inhalation.
LD50 (rabbit) 15,433 mg/kg
Repeated dose toxicity Species: rat, male and female NOAEL: 75 mg/kg Application Route: Oral Exposure time: 28 d
Dose: 75, 250 and 750 mg/kg bw/day Method: OECD Test Guideline 407 GLP: yes Symptoms:
Increased kidney and liver weights
Reproductive toxicity Effects on fertility : Test Type: One generation study Species: rat, male and female Application
Route: Inhalation Dose: 0, 100, 500 and 1000 ppm Duration of Single Treatment: 6 h General
Toxicity - Parent: NOAEC: 1,000 ppm General Toxicity F1: NOAEC: 100 ppm Symptoms:
Reduced fetal weight. Reduced offspring weight gain. Method: OECD Test Guideline 415 Result:
No reproductive effects. GLP: yes Effects on foetal development : Species: rat Application Route:
Inhalation Dose: 0, 100, 500, 1000, 2000 ppm Duration of Single Treatment: 15 d General
Toxicity Maternal: NOAEC: 500 ppm Teratogenicity: NOAEC: 2,000 ppm Developmental Toxicity:
NOAEC: 500 ppm Symptoms: Reduced body weight Method: OECD Test Guideline 414 Result:
Developmental toxicity occurred at maternal toxicity dose levels GLP: No data available
Reproductive toxicity - Assessment : No toxicity to reproduction Did not show teratogenic effects
in animal experiments.
Respiratory or skin Remarks: No data available
sensitization
Serious eye Species: rabbit Result: Mild eye irritation Remarks: No data available
damage/eye irritation
Skin Species: rabbit Result: Mild skin irritation
corrosion/irritation
STOT - repeated Target Organs: Auditory system Assessment: May cause damage to organs through prolonged or
exposure repeated exposure., The substance or mixture is classified as specific target organ toxicant,
repeated exposure, category 2.
STOT - single exposure No data available.
Titanium Dioxide(13463-67-7)
Carcinogenicity In lifetime inhalation studies rats were exposed for 2 years to respectively 10, 50, 250 mg/m3 of
repairable Ti02.
Dermal ALD (rabbit) >10000 mg/m3
Eye irritation slight irritation
Inhalation 4 h ALC >6.82 mg/l
ORAL ALD (rat) >2400 mg/kg
Sensistation Did not cause sensitsation on laboratory animals.
Skin irritation slight irritation
Toluene(108-88-3)
Aspiration toxicity Aspiration Toxicity - Category 1
Carcinogenicity Species: rat, (male and female) Application Route: inhalation (vapor) Exposure time: 103 wks
Dose: 0, 600, 1200 ppm Frequency of Treatment: 6.5 h/d, 5 d/wk NOAEL: No observed adverse
effect level: 1,200 ppm Method: OECD Test Guideline 453 Result: did not display carcinogenic
properties Symptoms: Erosion of nasal epithelium Species: rat, (male and female) Application
Route: inhalation (vapour) Exposure time: 103 wks Dose: 0, 600, 1200 ppm Frequency of
Treatment: 6.5 h/d, 5 d/wk NOAEL: No observed adverse effect level: 1,200 ppm Method: OECD
Test Guideline 453 Result: did not display carcinogenic properties Symptoms: Erosion of nasal
epithelium Species: rat, (male and female) Application Route: inhalation (vapour) Exposure
time: 103 wks Dose: 0, 600, 1200 ppm Frequency of Treatment: 6.5 h/d, 5 d/wk NOAEL: No
observed adverse effect level: 1,200 ppm Method: OECD Test Guideline 453 Result: did not
display carcinogenic properties Symptoms: Erosion of nasal epithelium , GLP: yes, Carcinogen
Further information Remarks: Symptoms of overexposure may be headache, dizziness, tiredness, nausea and
vomiting. Concentrations substantially above the TLV value may cause narcotic effects. Solvents
may degrease the skin.
Germ cell mutagenicity Genotoxicity in vitro : Test Type: Mammalian cell gene mutation assay Test species: Mouse
lymphoma cells Metabolic activation: with and without metabolic activation Method: OECD Test
Guideline 476 Result: negative : Test Type: Ames test Metabolic activation: with and without
metabolic activation Result: negative Genotoxicity in vivo : Test Type: Chromosome aberration
assay in vivo Test species: rat Cell type: Bone marrow Application Route: Intraperitoneal
Exposure time: 1 or 5 d Dose: 0, 0.025, 0.082, 0.247 ml/kg Result: negative Test Type:
Dominant lethal assay Test species: mouse (male) Application Route: inhalation (vapour)
Exposure time: 6 h/d, 5 d/wk for 8 wks Dose: 0, 100, 400 ppm Method: OECD Test Guideline
478 Result: negative Germ cell mutagenicity Assessment : Tests on bacterial or mammalian cell
cultures did not show mutagenic effects.
LC50 (rat, male and 28.1 mg/l Exposure time: 4 h Test atmosphere: vapor Method: OECD Test Guideline 403
female)
LD50 (rabbit) > 5,000 mg/kg
LD50 (rat, male) > 5,580 mg/kg
Repeated dose toxicity Species: mouse, male and female NOAEL: 625 mg/kg LOAEL: 1,250 mg/kg Application Route:
Oral Exposure time: 13 wks Number of exposures: 5 d/wk Dose: 312, 625, 1250, 2500, 5000
Group: yes GLP: yes Symptoms: death, Increased liver weight, ataxia, hypoactivity,
hypothermia Species: rat, male and female NOAEL: 300 Application Route: inhalation (vapour)
Exposure time: 6, 12, or 18 mths Number of exposures: 6 h/d, 5 d/wk Dose: 0, 30, 100, 300
ppm Method: OECD Test Guideline 453 Repeated dose toxicity - Assessment : Causes skin
irritation.
Reproductive toxicity Effects on fertility : Test Type: Two-generation study Species: rat, male and female Application
Route: Inhalation Dose: 0, 100, 500, 2000 ppm Frequency of Treatment: 7 days/week General
Toxicity - Parent: NOAEC: 500 ppm General Toxicity F1: NOAEC: 500 ppm Fertility: NOAEC:
2,000 ppm Symptoms: Reduced maternal body weight gain. Reduced offspring weight gain.
Method: OECD Test Guideline 416 Result: Animal testing did not show any effects on fertility.
GLP: yes Test Type: Fertility Species: rat, male and female Application Route: inhalation (vapor)
Dose: 0, 600, 1200 ppm Frequency of Treatment: 7 days/week General Toxicity - Parent:
NOAEC: 600 ppm Symptoms: Decreased sperm count Result: Animal testing did not show any
effects on fertility.
Reproductive toxicity Effects on fetal development : Species: rat Application Route: inhalation (vapour) Dose: 0, 250,
(cont.) 750, 1500, 3000 ppm Duration of Single Treatment: 10 d Frequency of Treatment: 6 hr/day
General Toxicity Maternal: NOAEC: 750 ppm Developmental Toxicity: NOAEC: 750 ppm
Symptoms: Maternal toxicity, Reduced body weight, Skeletal malformations. GLP: yes
Reproductive toxicity - Assessment : Some evidence of adverse effects on sexual function and
fertility, and/or on development, based on animal experiments.
Respiratory or skin Test Type: Maximization Test (GPMT) Species: guinea pig Result: Did not cause sensitization on
sensitization laboratory animals. GLP: yes
Serious eye Species: rabbit Result: Irritating to eyes. Method: OECD Test Guideline 405
damage/eye irritation
Skin Species: rabbit Exposure time: 4 h Result: Irritating to skin.
corrosion/irritation
STOT - repeated Inhalation Auditory system, Eyes May cause damage to organs through prolonged or repeated
exposure exposure., The substance or mixture is classified as specific target organ toxicant, repeated
exposure, category 2.
STOT - single exposure Exposure routes: Target Organs: Assessment: Remarks: Inhalation Central nervous system May
cause drowsiness or dizziness. The substance or mixture is classified as specific target organ
toxicant, single exposure, category 3 with narcotic effects.
Xylene(1330-20-7)
Acute dermal toxicity Acute toxicity estimate : 1,100 mg/kg Method: Expert judgment.
Acute inhalation Acute toxicity estimate, 4631 ppm Exposure time, 4 h Test atmosphere: gas Method; Calculation
toxicity method.
Acute toxicity Product Acute oral toxicity : Acute toxicity estimate : 3,523 mg/kg Method: Calculation method.
Aspiration Toxicity May be fatal if swallowed and enters airways.
Carcinogenicity Species: mouse, (male and female) Application Route: Oral Exposure time: 103 wk Dose: 0, 500
or 1000 mg/kg Frequency of Treatment: 5 days/week Method: Directive 67/548/EEC, Annex V,
B.32. Result: did not display carcinogenic properties GLP: No data available, Carcinogenicity -
Assessment : Animal testing did not show any carcinogenic effects.
Germ cell mutagenicity 12:00:00 AM
Germ cell mutagenicity Animal testing did not show any mutagenic effects.
Assessment
LC50 (rat, male) 6700 ppm Exposure time: 4 h Method: Directive 67/548/EEC, Annex V, B.2. GLP: No data
Inhalation available Assessment: The substance or mixture is classified as specific target organ toxicant,
single exposure, category 3 with respiratory tract irritation. Remarks: Acutely Toxic Category 4
LC50 (rat, male) Oral 3,523 mg/kg Method: EU Method B.1 (Acute Toxicity, Oral) Target Organs: Kidney, Bladder GLP:
no
Repeated dose toxicity Species: rat, male and female NOAEL: 250 mg/kg Application Route: Oral Exposure time: 103
wk Number of exposures: 5 d/wk Dose: 0, 250 or 500 mg/kg Assessment: The substance or
mixture is classified as specific target organ toxicant, repeated exposure, category 2.
Reproductive toxicity Effects on fertility : Test Type: Two-generation study Species: rat, male and female Application
Route: Inhalation Dose: 0, 25, 100 and 500 ppm Duration of Single Treatment: 6 h Frequency of
Treatment: 7 days/week General Toxicity - Parent: NOAEC: > 500 ppm General Toxicity F1:
NOAEC: > 500 ppm Early Embryonic Development: NOAEC: > 500 ppm Result: No reproductive
effects. Effects on fetal development : Species: rat Application Route: Inhalation Dose: 0, 100,
500, 1000 or 2000 ppm Duration of Single Treatment: 14 d Frequency of Treatment: 6 hr/day
General Toxicity Maternal: NOAEC: 500 ppm Teratogenicity: NOAEC: > 2,000 Developmental
Toxicity: NOAEC: 100 ppm Result: No teratogenic effects., Developmental toxicity occurred at
maternal toxicity dose levels Reproductive toxicity - Assessment : Animal testing did not show
any effects on fertility. Damage to fetus not classifiable
Respiratory or skin Remarks: No data available
sensitization
Serious eye Species: rabbit Result: Mild eye irritation
damage/eye irritation
Skin Species: rabbit Exposure time: 24 h Result: Irritating to skin Remarks: Skin irritation, Category
corrosion/irritation 2
STOT - repeated Target Organs: Liver, Kidney, Central nervous system Assessment: May cause damage to organs
exposure through prolonged or repeated exposure.
STOT - single exposure No data available.
Amorphous Silica(7631-86-9)
Additional ecological General notes: Do not allow product to reach ground water, water course or sewage system.
information
Bioaccumulative No further relevant information available.
potential
EC50 - Algee >10000 mg/l (Scenedesmus subspicatus) (72 h) (OCED 201) comparable substance
EC50 - Daphnia magna >1000 mg/l (Daphnia magna) (24 h) (OCED 202)
LCO - Zebra fish 10000 mg/l (zebra fish) (96 h) (static) (OCED203)
Mobility in soil No further relevant information available.
Persistence and The product is chemically and biologically inert. By the insolubility in water there is a separation
degradability at every filtration and sedimentation process.
BENZENE(71-43-2)
Additional ecological Toxic to aquatic life. An environmental hazard cannot be excluded in the event of unprofessional
information handling or disposal. Toxic to aquatic life.
EC50 10 mg/l Exposure time: 48 h Species: Daphnia magna (Water flea) static test Test substance:
yes Method: OECD Test Guideline 202
Ecotoxicology Acute aquatic toxicity Benzene : Toxic to aquatic life. Chronic aquatic toxicity Benzene : Harmful
Assessment to aquatic life with long lasting effects.
ErC50 100 mg/l Exposure time: 72 h Species: Pseudokirchneriella subcapitata (green algae) Test
substance: yes Method: OECD Test Guideline 201
LC50 5.3 mg/l Exposure time: 96 h Species: Oncorhynchus mykiss (rainbow trout) flow-through test
Test substance: yes Method: OECD Test Guideline 203
Persistence and Biodegradability: This material is expected to be readily biodegradable.
degradability
Results of PBT This substance is not considered to be persistent, bioaccumulating nor toxic (PBT). This
assessment substance is not considered to be very persistent nor very bioaccumulative (vPvB).
Carbon Black(1333-86-4)
Behavior in water Activated sludge, EC0 (3 h) > 800 mg/L. DEV L3 (TTC test)
treatment plants
Bioaccumulation Potential bioaccumulation is not expected because of the physicochemical properties of the
Potential substance
EC50 (Scenedesmus > 10,000 mg/L, OECD (Guideline 201)
subspicatus)
EC50 Daphnia magna >5600 mg/l (24 h) OECD (Guideline 202)
(water flea)
Environmental fate Carbon black is an inert solid, stable and insoluble in water or organic solvents. Its vapor
pressure is negligible. Based on these properties it is expected that carbon black will not occur in
air or water in relevant amounts. Also potential for distribution via water or air can be dismissed.
The deposition in soil or sediments is therefore the most relevant compartment of fate in the
environment.
LC50 Brachydanio reio >1000 mg/l (96 h) OECD (Guideline 203)
(zebra fish)
NOEC 50 > 10,000 mg/L, OECD (Guideline 201)
(Scenedesmus
subspicatus)
n-Butyl Acetate(123-86-4)
Bioaccumulative No data available.
potential
Chronic Toxicity Fish: No data available. Aquatic invertebrates: No data available. Toxicity to Aquatic Plants: No
data available.
LC-50 (Fathead 18 mg/l, (96 h)
Minnow) Acute Toxicity
LC-50 (Water Flea) 44 mg/l , (48 h)
Aquatic invertebrates
Mobility in soil Known or predicted distribution to environmental compartments: No data available.
Other adverse effects No data available.
Persistence and 83 % (28 d), Biological Oxygen Demand:BOD-5: 730 mg/g, Chemical Oxygen Demand:1,010
degradability mg/g, BOD/COD ratio:72 %.
Results of PBT and No data available.
vPvB assessment
n-Methyl-2-pyrrolidone(872-50-4)
Additional information Sum parameter Chemical oxygen demand (COD): (DIN 38409 Part 41) approx. 1,600 mg/g
Biochemical oxygen demand (BOD) Incubation period 5 d: < 2 mg/g Absorbable organically-
bound halogen (AOX): This product contains no organically-bound halogen.
Bioaccumulative Assessment bioaccumulation potential Because of the n-octanol/water distribution coefficient
potential (log Pow) accumulation in organisms is not to be expected.
EC50 (Algae) > 500 mg/l, (72 h), Scenedesmus subspicatus (DIN 38412 Part 9) The details of the toxic effect
relate to the nominal concentration.
EC50 (Daphnia) > 1,000 mg/l, (24 h), Daphnia magna (DIN 38412 Part 11, static) The details of the toxic effect
relate to the nominal concentration.
LD50 (fish) > 500 mg/l, Salmo gairdneri, syn. O. mykiss (static) The details of the toxic effect relate to the
nominal concentration.
Microorganisms/Effect Toxicity to microorganisms DIN EN ISO 8192 aquatic activated sludge, industrial/EC50 (0.5 h):
on activated sludge > 600 mg/l The details of the toxic effect relate to the nominal concentration.
Mobility in soil Assessment transport between environmental compartments The substance will rapidly
evaporate into the atmosphere from the water surface. Adsorption to solid soil phase is not
expected.
Persistence and Assessment biodegradation and elimination (H2O) Readily biodegradable (according to OECD
degradability criteria). Elimination information 73 % BOD of the ThOD (28 d) (OECD 301C; ISO 9408;
92/69/EEC, C.4-F) (aerobic, Inoculum conforming to MITI requirements (OECD 301C)) Readily
biodegradable (according to OECD criteria). Assessment of stability in water In contact with
water the substance will hydrolyse slowly.
P.M. Acetate(108-65-6)
Aquatic invertebrates NOEC (daphnia, 21 d): >= 100 mg/l EC-50 (daphnia, 21 d): > 100 mg/l
Bioaccumulative No data available.
potential
Biological Oxygen 363 mg/g 1,050 mg/g
Demand
Chemical Oxygen No data available.
Demand
Chronic Toxicity Fish LC-50 (Oryzias latipes, 14 d): 63.5 mg/l NOEC (Oryzias latipes, 14 d): 47.5 mg/l
LC50 - Daphnoid - 408 mg/l (48 h)
Auuatic invertebrates
LC50 - Fathead Minnow 161 mg/l (96 h)
- Toxicity to Fish
Mobility in soil No data available.
Other adverse effects No data available.
Persistence and Biodegradation - 90 % (28 d, Ready Biodegradability: CO2 Evolution Test) Readily biodegradable
degradability
Results of PBT and No data available.
vPvB assessment
Toxicity to Aquatic EC-50 (Selenastrum capricornutum, 96 h): > 1,000 mg/l NOEC (Selenastrum capricornutum, 96
Plants h): >= 1,000 mg/l
Phenylethane(100-41-4)
Bioaccumulative Partition coefficient: noctanol/water : log Pow: 2.92
potential
EC50 (Daphnia magna 1.8 mg/l Exposure time: 48 h Test Type: static test
(Water flea))
EC50 5.4 mg/l Exposure time: 72 h Test Type: static test Analytical monitoring: yes Method: Static
(Pseudokirchneriella GLP: yes
subcapitata)
LC50 (Oncorhynchus 4.2 mg/l Exposure time: 96 h Test Type: semi-static test
mykiss (rainbow
trout))
Mobility in soil No data available.
Other adverse effects Results of PBT and vPvB assessment : This substance is not considered to be persistent,
bioaccumulating nor toxic (PBT). This substance is not considered to be very persistent nor very
bioaccumulating (vPvB).
Persistence and Biodegradability: Inoculum: activated sludge Concentration: 22 mg/l Result: Readily
degradability biodegradable. Biodegradation: 70 % Exposure time: 28 d GLP: yes
Toxicity to daphnia and (Daphnia): 3.6 mg/l Toxicity to bacteria : GLP: Remarks: No data available Ecotoxicology
other aquatic Assessment Chronic aquatic toxicity : Harmful to aquatic life with long lasting effects.
invertebrates (Chronic
toxicity)
Titanium Dioxide(13463-67-7)
LC50 fish Fathead minnow 96 h >1000 mg/l
Toluene(108-88-3)
Bioaccumulative Partition coefficient: noctanol/water : log Pow: 2.73
potential
EC50 (Ceriodaphnia 3.78 mg/l Exposure time: 48 h Test Type: Renewal
dubia)
EC50 (Chlorella 134 mg/l Exposure time: 3 h Test Type: static test
vulgaris (Fresh water
algae))
IC50 (Bacteria) 84 mg/l Exposure time: 24 h, Test Type: Static Ecotoxicology Assessment Acute aquatic toxicity
: Toxic to aquatic life. Chronic aquatic toxicity : Toxic to aquatic life with long lasting effects.
LC50 (Oncorhynchus 5.5 mg/l Exposure time: 96 h Test Type: flow-through test
mykiss (rainbow
trout))
Mobility in soil No data available.
Other adverse effects No data available.
Persistence and Biodegradability : Inoculum: Sewage Biodegradation: 100 % Remarks: Readily biodegradable
degradability
Xylene(1330-20-7)
Bioaccumulative Partition coefficient: noctanol/water : log Pow: 2.77 - 3.15
potential
EC50 4.36 mg/l End point: Growth rate Exposure time: 73 h Test Type: static test Analytical
(Pseudokirchneriella monitoring: yes
subcapitata)
IC50 (Daphnia magna 1 mg/l Exposure time: 24 h Test Type: static test Test substance: Information given is based on
(Water flea)) data obtained from similar substances. Method: OECD Test Guideline 202 GLP
LC50 (Oncorhynchus 2.6 mg/l Exposure time: 96 h Test substance: Information given is based on data obtained from
mykiss (rainbow similar substances. Method: OECD Test Guideline 203 GLP: No data available
trout))
Mobility in soil No data available.
Persistence and Biodegradability : Inoculum: activated sludge Result: Readily biodegradable. Biodegradation: 72
degradability % Exposure time: 20 d
USDOT GROUND
DOT (DEPARTMENT OF TRANSPORTATION)
PROPER SHIPPING NAME (DOT) : Paint, flammable liquid
HAZARDS CLASS : 3
UN/NA NUMBER : UN1263
PACKING GROUP : PG II
EMERGENCY RESPONSE GUIDE (ERG) : 128
IATA (AIR)
DOT (INTERNATIONAL AIR TRANSPORTATION ASSOCIATION)
PROPER SHIPPING NAME : Paint, flammable liquid
HAZARDS CLASS : 3
UN/NA NUMBER : UN1263
PACKING GROUP : PG II
EMERGENCY RESPONSE GUIDE (ERG) : 128
IMDG (OCEAN)
PROPER SHIPPING NAME : Paint, flammable liquid
HAZARDS CLASS : 3
UN/NA NUMBER : UN1263
PACKING GROUP : PG II
EMERGENCY RESPONSE GUIDE (ERG) : 128
MARINE POLLUTANT : No
SPECIAL PRECAUTIONS : P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking. P235 Keep cool.
US FEDERAL REGULATIONS
All ingredients in Section #3 are TSCA (Toxic Substance Control Act) listed.
OSHA HAZARDS : Flammable liquid, Moderate skin irritant, Moderate eye irritant, Carcinogen.
EPCRA - Emergency
CERCLA REPORTABLE QUANTITY
Carbon Black (CAS# 1333-86-4) : RQ(lbs) 5000
SARA 304 Extremely Hazardous Substances Reportable Quantiity : This material does not contain any components
with a section 304 EHS RQ.
SARA TITLE III (SUPERFUND AMENDMENRS AND REAUTHORIZATION ACT)
SARA 311/312 Hazards : Fire Hazard, Acute Health Hazard, Chronic Health Hazard
SARA 313 :
Not reportable.
INTERNATIONAL REGULATIONS
NATIONAL REGULATIONS
STATE REGULATIONS
CALIFORNIA PROPOSITION 65
*This product contains (a) chemical (s) known to the State of California to cause cancer.
+This product contains (a) chemical (s) known to the State of California to cause birth defects or other reproductive harm.
MANUFACTURER DISCLAIMER : The information contained in this Safety Data Sheet is considered to be true and
accurate. Cardinal Industrial Finishes makes no warranties, expressed or implied, as to the accuracy and adequacy of this
information. This data is offered solely for the user's consideration, investigation and verification.