Scribd
Upload
193 views5 pages

File 1 Extra MCQs NDDS

Uploaded by

1091 Sharma Shahil
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
193 views5 pages

File 1 Extra MCQs NDDS

Uploaded by

1091 Sharma Shahil
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 5

File 1 NDDS MCQs

1. Crystallinity in a polymer leads to


A. low diffusion rate
B. more flexible
C. high diffusion rate
D. increased hydrolysis

2. Which of the following is a natural polymer


A. Collagen
B. Poly D,L-lactic -co-glycolic acid
C. Teflon
D. Nylon

3…......................is used as a hydrophobic matrix to formulate a sustained release drug


delivery
system
A. Gelatin
B. Ethyl cellulose
C. Xanthan gum
D. Sodium carboxymethyl cellulose

4. The biological factor significantly affecting the bioavailability of Controlled release


dosage form
A. Absorption
B. Refractive index
C. Surface tension
D. Solubility

5.Poloxamer is available in various following common grades excluding the


grade…………………….
A. 20
B. 88
C. 407
D. 188
6. Drugs with……………… therapeutic index are unsuitable for incorporation in Sustained
release formulations.
A. Low
B. High
C. Intermediate
D. Very high

7. In the Reservoir system, the mechanism of drug release involves the drug
………………………..
A. Dissolution
B. Diffusion
C. Dissolution and Diffusion
D. In situ dissolution

8. In matrix devices drug is........................throughout a polymer matrix.


A. Dispersed Homogeneously
B. Dispersed Abruptly
C. Dissolved Homogenously
D. Mixed Non Homogenously

9. Polymers used as mucoadhesive polymers does not include


A. Hydroxy propyl cellulose
B. Collagen
C. Sodium carboxy methyl cellulose
D. Ethyl cellulose

10. PLGA is a.........................polymer used in the sustained/ controlled drug delivery systems
A. Natural polymer
B. Natural copolymer
C. Synthetic copolymer
D. Synthetic polymer

11. Identify the characteristics of Osmotic pressure-controlled systems


A. Hollow systems with drug surrounded by polymer membrane
B. Formation of complex between drug and ion exchange resin
C. Releases drug at zero order kinetics
D. Buffers that adjust pH to desired value

12. Controlled release formulations exhibit kinetics


A. First order
B. Second order
C. Pseudo first order
D. Zero order

13. Progestasert IUD exhibits which type of controlled drug delivery


A. Polymer membrane permeation
B. Activation modulated
C. Polymer matrix diffusion
D. Micro-reservoir partition

14. Identify the approach not useful to increase gastric retention time for Gastro retentive
drug delivery system
A. High density systems
B. Effervescent systems
C. Swelling systems
D. Compressing systems

15.Which of the following is used to produce effervescent Gastro retentive drug


delivery system
A. Magnesium stearate
B. Sodium bicarbonate
C. Magnesium carbonate
D. Sodium hydroxide

16.Which of the following is not an evaluation parameter for Gastro retentive drug
delivery system
A. Floating time
B. Specific gravity
C. Bioadhesive strength
D. Conductivity test
17.Which of the following is a wrong statement for Gastro retentive drug delivery systems
A. Useful to reduce first pass effect of the drug
B. Useful to provide local and systemic effect of the drug
C. Useful to increase gastric retention of the drug
D. Useful to target site specific release of the drug

18.Floating drug delivery systems have a bulk density


A. Greater than gastric fluids
B. Lesser than gastric fluids
C. Same as gastric fluids
D. Double that of gastric fluids

19.Hollow microspheres, a non-effervescent approach for gastro retentive drug delivery


system are also known as
A. Microballs
B. Microballoons
C. Floating beads
D. Macrobeads

20. Which of the following is not a hydrocolloid


A. Chitosan
B. Polycarbonate
C. HPMC
D. HEC

21. Which of the following is a criteria for selection of drug candidate for GRDDS
A. Low absorption window
B. Faster onset of action
C. Potent drug
D. Smaller therapeutic window

22.Following is the example of ophthalmic insert undergoing erosion


A. Lacrisert
B. Ocustrip
C. Ocufit
D. Contact lens

23.Ocular drug transport usually follows various following pathways except………………


A. Inactive transport
B. Active transport
C. Facilitated transport
D. Passive diffusion

24. A particulate ocular carrier that binds to mucin is


A. Liposome
B. Niosomes
C. Solid nanoparticles
D. Nanolipid carriers

25. An ocular device containing hydroxypropycellulose is


A. Lacrisert
B. SODI
C. Ocusert
D. Minidisc

26. ..,…..,……. Is an example of natural polymer used in the formulation development


of ocular inserts
A. Collagen
B. Hydroxypropyl methyl cellulose
C. Ethyl cellulose
D. Polyvinvyl Alcohol

27. SODI stands for…..,……..


A. Soluble ophthalmic drug insert
B. Saturated ophthalmic drug insert
C. Saturated ocular drug interaction
D. Soluble ophthalmic dose interaction

28. The effectiveness of liposome in ocular drug delivery system depends on following
factors excluding
E. Size
F. Colour
G. Drug encapsulation efficiency
H. Charge of liposome

29. Absorption of drugs through the skin is


a. by transepidermal and shunt pathway
b. through hair follicles
c. by Pinocytosis
d. mainly by transfollicular route

30. Dissolution apparatus for in vitro drug release from transdermal patches is
a. USP 5
b. USP 1
c. USP 3
d. USP 7

31.An excipient added to transdermal devices to prevent loss of the drug and facilitate
printing is
a. Polyurethane
b. Polysiloxanes
c. Pluronics
d. Dimethyl formamide

32. Major pathway of drug transport through skin is


A. Passive
B. Active
C. Carrier mediated
D. Osmosis

33. Membrane controlled transdermal drug delivery systems have


a. solid/liquid drug reservoirs
b. microscopic spheres
c. solid drug dispersed in lipophilic/hydrophilic polymer
d. multilayered laminates containing the drug
34. Basic components of Transdermal drug delivery system includes the following except
a. Polymer matrix
b. Release liner
c. Adhesive
d. Metal ring

35. .................,a hydrophilic matrix is used to formulate a sustained drug release tablet.
A. Eudragit R100
B. Hydroxypropylmethyl cellulose
C. Ethyl cellulose
D. Triacetin

36. ………………. is the dosage form or medication that prolongs the therapeutic activity of
drug.
a. Controlled drug delivery system
b. Sustained drug delivery system
c. Delayed drug delivery system
d. Pulsatile drug delivery system

37. ______________ is a non-biodegradable implant polymer widely used in the preparation


of ocular implants

a. Polylactic acid
b. Polyglycolic acid
c. Polyvinyl alcohol
d. Polyethylene glycol

38. are ocular inserts fabricated from porcine scleral tissue resembling the human scleral tissue.

a. Lacrisert
b. Ocular wafers
c. Collagen shields
d. Ocular implant

You might also like