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    CoAs... Acetona. TDS (Panreac AppliChem)

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    Maikel Perez Navarro

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    © All Rights Reserved
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    CoAs... Acetona. TDS (Panreac AppliChem)

    Uploaded by

    Maikel Perez Navarro
    3 views3 pages

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    © © All Rights Reserved

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    3 views3 pages

    CoAs... Acetona. TDS (Panreac AppliChem)

    Uploaded by

    Maikel Perez Navarro

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    Ed.: 19 . Vig.: 06.07.2017 . Prod.

    : 141007

    PRODUCT CODE: 141007

    Acetone (USP, BP, Ph. Eur.) pure, pharma grade

    C3H6O
    CH3COCH3

    M.= 58,08 CAS [67-64-1] EINECS 200-662-2


    TARIC 2914 11 00 00

    SYNONYMS: 2-Propanone, ß-Ketopropane, Dimethylketone, Pyroacetic Ether

    PHYSICAL DATA: liquid, Soluble in water Miscible with water and most of the solvents • D 20/4 0,791 • M.P.: -94
    °C • B.P.: 56,5 °C • n20/D : 1,3591 • Flash P.: -20 °C • Ign. T.:465 °C • Vap. press. (20 °C) 233 hPa • Viscosity 25
    °C 0,31 mPa.s • D. M. 20 °C 2,7 Debye • Dielec. constant25 °C 20,7 • Evap. number (DIN 53170) 2,1 • Heat evap.
    56 °C 521 KJ/Kg • Satur. conc. 20 °C 533 g/m3 • Expl. limit2,2 %(V)12,8 %(V) •
    BIBLIOGRAPHY: Merck Index 13, 67 14, 66 Sax ABC750 • Safety 2 , 20 A • Kühn-Birett A 3 • Beilstein 1 , 635 I ,
    335 II , 692 III , 2696 IV , 3180 • BRN 635680 • Fieser 213 34 69 • ACS XI • ISO 6353/2-1983 R – 12 , 16 •
    BP.2020 • USP -NF 37 • Ph. Eur. 9.0 (2017) 10.0 (2020) • F.C.C 10 11 • Directive
    88/344/E.C.E.92/115/E.C.E.94/52/EC97/60/EC (27/10/1997) 2009/32/CE • Royal Decree 472/1990 (6/4/1990) ,
    2667/1998 (11 /12/1998), 1101/2011 (22/7/2011) •

    HAZARDOUS: C.E: 606-001-00-8 • RTECS: AL 3150000 • LD50 oral rat 5.800 mg/kg • VLA-ED 500 ppm1.210
    mg/m3 ECTLV 500 ppm1.210 mg/m3
    Derived No Effect Level (DNEL)
    Workers Dermal, long exposure (local) 186mg/kg bw/24h Workers Inhalation, acute (local) 2.420 mg/m3 Workers
    Inhalation, long term (local) 1.210 mg/m3 Population, oral, long term (systemic) 62mg/kg bw/24h Population,
    Dermal, long exposure (systemic) 62mg/kg bw/24h Population Inhalation, long term (systemic) 200 mg/m3
    Predicted No Effect Concentration (PNEC)
    Marine water 1.06mg/l Freshwater 10.6mg/l Freshwater Sediment 30.4mg/l Marine water Sediment 3.04mg/l
    Soil 0.112mg/l Sewage treatment plant 29.5mg/l
    H: H225 • H319 • EUH066 • H336 •
    P: P210 • P233 • P241 • P303+P361+P353 • P304+P340 • P501 • P235 •

    TRANSPORT REGULATIONS: UN: 1090 • ADR: 3/II • IMDG: 3/II • IATA: 3/II • PAX: 353 • CAO: 364 • (D/E) •

    WEIGHT/VOLUME INFORMATION: 1l~0,789 kg 1kg~1,267 l

    OBSERVATIONS: Product controlled as a drug precursor. • Storage away from direct light. •

    SPECIFICATIONS:

    Minimum assay (G.C.) 99,5%


    Identity :
    Identity according to Pharmacopoeias: passes test
    Density at 25/25 <= 0,789
    Density at 20/20 0,790-0,793

    Maximum limit of impurities


    Appearance of solution passes test
    Acidity passes test

    Alkalinity passes test


    Insoluble matter in H2O passes test
    Non-volatile matter 0,004 %
    Reducing substance to KMnO4 passes test
    Residual solvents (Ph.Eur/USP) passes test
    Related substances (G.C.)
    Methanol 0,05 %
    2-Propanol 0,05 %
    Benzene 0,0002 %
    Other impurities 0,05 %
    Ethanol (G.C.) 500 ppm
    Water (H2O) 0,3 %

    Elemental impurities (ICH Q3D):


    Class 1
    Cd 0,5 ppm
    Pb 0,5 ppm
    As 1,5 ppm
    Hg 1,5 ppm
    Class 2A
    Co 5 ppm
    V 10 ppm
    Ni 20 ppm

    Class 2B
    Tl 0,8 ppm
    Au 10 ppm
    Pd 10 ppm
    Ir 10 ppm
    Os 10 ppm
    Rh 10 ppm
    Ru 10 ppm
    Se 15 ppm
    Ag 15 ppm
    Pt 10 ppm

    Class 3
    Li 55 ppm
    Sb 120 ppm
    Ba 140 ppm
    Mo 25 ppm
    Cu 250 ppm
    Sn 600 ppm
    Cr 25 ppm

    Ed.: 19 . Vig.: 06.07.2017 . Prod.: 141007

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