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    3 views12 pages

    Screenshot 2023-05-12 at 10.49.02 PM

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    ayeshaashfaq3210

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    LIPOMA

    Benign soft tissue tumor


    • It’s a benign soft tissue tumor composed of
    mature adipocytes enclosed in a capule of
    connective tissue
    • Most common soft tissue tumor
    Location / Site:
    • Usually subcutaneous in location , often found
    in these sites
    • Neck
    • Shoulder
    • Back
    • Trunk
    • Proximal extremeties
    Causes :
    • In 50-60% cases there’s evidence of cytogenic
    abnormalities ( rearrangement in chromosome
    12 – most common )
    • Hereditary conditions ; familial multiple
    lipomatosis
    • Gardeners syndrome
    • Dercum’s syndrome
    • Minor injuries ; controversial
    Classification
    • They’re mostly found in 40-60 age group , but
    can also affect young adults and children
    • Based on location :
    • Intramuscular
    • Synovial lipomatosis
    • Inter muscular
    • Peri/para osteal
    • Intradural etc
    Morphology
    • Gross : Subcutaneous lipoma
    • Yellow, Soft well circumscribed lobulated
    tumor .
    • They have a thin capsule ( presence of capsule
    differnenciates it from subcut fat )
    • Microscopic :
    • Mature adipocytes with small eccentrically
    placed nuclei
    • Fibrous septa traversing through adipocytes .
    Liposarcoma
    Variants of lipoma
    • Chondroid lipoma
    • Angiolipoma
    • Fibrolipoma
    • Myelolipoma
    • Ossifying Lipoma
    • Myxolipoma
    • Spindle cell lipoma
    • Pleomorphic Lipoma
    Clinical features
    • 1-6 cms
    • Slip sign
    • Donot exhibit differential warmth
    • Painless , soft , non tender
    Complications
    • Myxomatoud degeneration
    • Saponification
    • Calcification
    • Infection
    • Ulceration
    • Malignant transformation ; though rare .

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