LECTURE 1 BIO 101
LECTURE 1 BIO 101
LECTURE 1 BIO 101
WEEK ONE
All living things are made up of tiny microscopic units as their building blocks, this
microscopic units are known as cells, which carry out all the processes that categorised the
Definition: The cell is the basic structural and functional unit in all animals in other words it
Cell history
● In 1665 an English botanist called Robert Hooke used a simple microscope to examine
the cork from a tree bark, He observed a honey comb structures which he named cells.
● Later between 1808 –1809 the works of Mirbel and Lamarck confirmed Hook’s idea.
● In 1834 Felix Dujardin discovered the living part of the cell which he named “sarcode”
● In 1839 Theodor Schwann a German zoologist discovered that animals are made up of
cells.
Cell theory
Jointly Theodor Schwann and Mathias Schleiden jointly formulated what is referred to as the
II.The cell is the structural and functional units of all living organism.
IV.A cell contains information for its structural and functional development in its nucleic acid.
TYPES OF A CELL
1) Prokaryotic cell; Are mostly unicellular lacking true nucleus thus their genetic material
2) Eukaryotic cell: Are mostly multicellular except protoctista. There DNA is enclosed
1. Single and free living cells: An organism that consist of one cell is said to be called
unicellular, acellular or monads. Such animals lives independently without relying on other
cells, thus is able to show all the basic characteristics of living things e.g Amoeba, Euglena,
An Amoeba
2. Single cells living as a colony: Many cells exists as a living single colony with each member
cell independent of the other in body metabolism, but are connected with delicate strands of
3. Single cells living as filaments: Living cells may also exists as a filament. Filaments are
made up of cylindrical cells joined end-to-end in a single row e.g Spirogyra, Oscillatoria and
Aphanizomenon.
A Filament of Spirogyra
cells interdependent on each other in performing a particular function. Humans are reported to
have about 10 trillion cells performing different functions either as tissues, organs or systems.
ORGANISATION OF LIFE
All living things especially animals are highly organised depending on the complexity of their
morphology and physiology. This organisation occurs in levels such that the simplest
The Cell
The cellular level is the most fundamental level of organisation. Organisms that are found under
this category are made up of a single cell, examples of such organisms includes among animals;
Amoeba, paramecium, bacteria e.t.c. While under plants we have euglena, clamydomonas, and
chlorella.
The Tissue
specific function. Certain organisms are found to exist under the tissue level of organisation
where their whole structure is made up of a few collection of cells jointly working as a living
individual example of such organisms includes; hydra, jelly fish, sea walnuts, e.t.c.
In multicellular organisms such as higher plants and animals different kinds of tissues were
In animals there four different types of tissues classified according to their function.
1. Epithelial Tissues: Epithelial tissue are group of cells covering the body surface. It is made
up of closely packed cells with almost no intercellular space. Epithelial tissues are specialised
to form a covering or lining of the internal body surfaces (known as ectothelium) and the
external body surfaces (known as the endothelium). Each epithelial tissue regardless of the
type, is usually separated by a thin sheet of connective tissue called basement membrane. The
basement membrane provides structural supports and also binds it to neighbouring structures.
Epithelial tissue can be divided into two groups depending on the number of layers it is
composed. Epithelial tissues which are only one cell thick is known as simple epithelium while
the tissues that are made up of more than one cell are called stratified epithelium.
I. Simple epithelium
Simple epithelium can be subdivided into 5 types according to the shape and function of their
cells.
Squamous cells have the appearance of thin, flat plates, with a horizontal flattened, elliptical
nuclei. This type of tissue form the lining of cavities such as mouth, blood vessels
b. Cuboidal epithelium:
This type of epithelium is made up of cells that are roughly square or cuboidal in shape. Each
cell has a spherical nucleus at the centre of the cytoplasm. Cuboidal cells are mostly found in
Columnar epithelium cells are elongated and column shaped. The nuclei are elongated and are
usually located near the base of the cells. Columnar epithelium forms the lining of the stomach
and intestines. Some columnar cells are specialised for sensory reception such as in the nose,
These are simple columnar epithelial cells, but in addition they possess a fine hair like out
growths on their free surfaces called cilia. These cilia are capable of rapid rhymic wave like
beating in a certain direction which allows mucus to flow. Ciliated epithelium is usually found
in the air passage like nose, uterus and fallopian tubes of females.
e. Glandular epithelium: Columnar epithelium with goblet cells is called glandular epithelium,
the presence of these goblet cells enable the tissue to synthesis and secrete certain substances
Stratified epithelium are group of different types of cells forming two or more layers .Mostly
stratified epithelium is found in body lining that have to withstand wear and tear. E.g the
● Protection: Epithelial cells found in the skin protect underlying tissue from mechanical injury,
harmful chemicals, invading viruses and bacteria and from excessive water loss.
● Sensation: Some special columnar epithelium with sensory receptors help in transmission of
● Secretion: Glandular epithelium helps in secretion of specific chemicals needed by the body.
● Absorption: Certain epithelial cells lining the small intestine absorbs nutrients from the
digestive system.
● Excretion: Epithelial tissue in the kidney excrete waste product from the body through selective