GRADE – XII – REVISION 29/11/2024

WORKSHEET CHAPTER:5 “ MOLECULAR BASIS OF INHERITANCE”

CLASS : SUBJECT : BIOLOGY

ROLL NO. _________NAME _______________ MARKS OBTAINED___

TIME:30 MINUTES MM:20 DATE :_____/______/______

1. Nucleic acids are polymer of------------------------------------- 1

(a) Nucleosides (b) Proteins (c) Glycoproteins (d) Nucleotides

2. Directions: In the following questions, a statement of assertion is followed by a

statement of reason. Mark the correct choice as: (a) If both Assertion and Reason are true
and Reason is the correct explanation of Assertion. (b) If both Assertion and Reason are
true but Reason is not the correct explanation of Assertion. (c) If Assertion is true but
Reason is false. (d) If both Assertion and Reason are false.

Assertion: The two chains of DNA have anti-polarity. Reason: In one chain of DNA, ribose
sugar at 5′ end consists of a free phosphate moiety while at the other end the ribose has
a free 3′ OH group.

3. (i) Where does peptide bond formation occur in a bacterial ribosome?

(ii) Name the scientist who called tRNA an adaptor molecule.

4. Why does hnRNA undergo splicing? Where does splicing occur in the cell? ------------2

5. A structural gene has two DNA strands X and Y shown along side. Identify the template
strand. 2

6. Show DNA replication with the help of a diagram only. 2

7. Describe the structure of a nucleosome.

8. Answer the questions based on the dinucleotide shown below. 3

(i) Name the type of sugar guanine base is attached to. (ii) Name the linkage connecting
the two nucleotides. (iii) Identify the 3′ end of the dinucleotide. Give a reason for your
answer.

9. How did Hershey and Chase established that DNA is transferred from virus to bacteria?
5
 WORK SHEET CLASS : XII BIOLOGY CHAPTER 6: “EVOLUTION”

ROLL NO. ____________ NAME_______________ DATE:____/____/_____

TIME: 30 MINUTES MM: 20 MARKS OBTAINED:________

1. The primate which existed 15 mya was-------------------------------------------------- 1

(a) Homo habilis (b) Australopithecus (c) Ramapithecus (d) Homo erectus

2. Assertion: According to big-bang hypothesis about 20 billion years ago universe was a
big ball of only neutrons. Reason: Movement of these particles is known to generate
tremendous heat which caused explosion due to temperature and pressure changes.

3. According to Hardy-Weinberg principle, the allele frequencies in a population are stable

and remain constant through generations. When the frequency differs from the expected
values, the difference indicates the extent (direction) of evolutionary change. Disturbance
in the genetic equilibrium or Hardy-Weinberg equilibrium in a population can be
interpreted as resulting in evolution. Write the algebraic equation representing Hardy-
Weinberg equilibrium.---1

4. Why are analogous structures a result of convergent evolution? 2

5. Identify the following pairs as homologous or analogous organs----------------------------- 2

(a) Sweet potato and potato. (b) Eye of Octopus and eye of mammals. (c) Thorns of
Bougainvillea and tendrils of Cucurbita. (d) Forelimbs of bat and whale.

6. According to Hugo de Vries what is saltation? 2

7. Name the ancestors of a man based on the features given below.------------------- 3

(i) Human-like, meat-eater with 900 cc brain, lived in Java. (ii) More human-like with brain
size 1400 cc, lived in Central Asia, used hides and buried their dead. (iii) Human-like,
vegetarian, with brain capacity between 650-800 cc.

8. Given below is a diagrammatic representation of the experimental setup used by SL

Miller for his experiment. 3

(i) Write the names of different gases contained and the conditions set for the reaction in
the flask A. (ii) State the type of organic molecule he collected in the water at B. (iii) Write
the conclusion he arrived at.

9. Describe the three different ways by which natural selection can affect the frequency
of a heritable trait in a population.
 Work sheet chapter 7: “HUMAN HEALTH AND DISEASE”

CLASS: XII SUBJECT: BIOLOGY

ROLL NO. _______NAME : ____________ DATE: ___/____/___

TIME: 30 MINUTES MM: 20 MARKS OBTAINED________

1. Diseases are broadly grouped into infectious and non-infectious diseases. In the list
given below, identify the infectious diseases. (i) Cancer (ii) Influenza (iii) Allergy (iv) Small
pox

(a) (i) and (ii) (b) (ii) and (iii) (c) (iii) and (iv) (d) (ii) and (iv)

2. Which technique is used to detect AIDS?

A. Northern blot and ELISA b. Immuno blot and ELISA

c. Western blot and ELISA d. Southern blot and ELISA

3. In malignant tumors, the cells proliferate, grow rapidly and move to other parts of the
body to form new tumors. This stage of disease is called

(a) metagenesis (b) metastasis (c) teratogenesis (d) mitosis

4. Which of the following are the reason(s) for rheumatoid arthritis? Choose the correct
option.

(i) The ability to differentiate pathogens or foreign molecules from self cells increases. (ii)
Body attacks self cells (iii) More antibodies are produced in the body (iv) The ability to
differentiate pathogens or foreign molecules from self cells is lost (a) (i) and (ii) (b) (ii)
and (iv) (c) (iii) and (iv) (d) (i) and (iii)

5. Which of the following antibodies form innate immunity? (a) IgE (b) IgD (c) IgM (d) IgG

6. Haemozoin is a

(a) precursor of hemoglobin

(b) toxin released from Streptococcus infectedcells

(c) toxin released from Plasmodium infected cells

(d) toxin released from Haemophilus infected cells

7. Which of the following is not the causal organism for ringworm?

(a) Microsporum (b) Trichophyton

(c) Epidermophyton (d) Macrosporum

8. In the following questions a statement of assertion followed by a statement of reason is

given. Choose the correct answer out of the following choices. (a) Assertion and reason
both are correct statements and reason is correct explanation for assertion. (b) Assertion
and reason both are correct statements but reason is not correct explanation for
assertion. (c) Assertion is correct statement but reason is wrong statement. (d) Assertion
is wrong statement but reason is correct statement.
Assertion : Second infection of the same pathogen is quickly eliminated. Reason :
Preformed memory B and T-cells elicit a quick and vigorous attack on pathogens.

9. Assertion: Proto-oncogenes are cellular genes required for normal growth.

Reason: Under certain conditions they lead to the oncogenic transformation of the cell.

10. Retroviruses have no DNA. However, the DNA of the infected host cell does possess
viralDNA. How is it possible?

11. What is cancer? How is a cancer cell different from normal cell?

12. You have attended a birthday party hosted by one of your classmates. You found some
guests at the party sitting in a corner making a lot of noise and consuming ‘something’. After
awhile one of the boys from the group started screaming, behaving abnormally and sweating
profusely. On enquiry you found that the group members were taking drugs.
(a) Would you inform your parents/school authorities? Yes/No. Give reasons is support
of your answer.
(b) Write any two ways that you will suggest to your school principal so as to promote
awareness amongst the youth against the use of these drugs
Work sheet chapter 10: “Biotechnology & Its Applications”
CLASS : XII SUBJECT: BIOLOGY
ROLL NO. _______NAME : ____________ DATE: ___/____/___

1. The genetically modified brinjal in India has been developed 1

for
A. Drought resistance B. Enhancing mineral content
C. Enhancing shelf life D. Insect resistance
2 Which kind of therapy was given in 1990 to a four-year-old girl 1
with ADA deficiency? (Adenosine Deaminase)
A. Radiation Therapy B. Gene Therapy
C. Radiation Therapy D. Immunotherapy
3 The genetically modified brinjal in India has been developed 1
for
A. Enhancing mineral content B. Insect-resistance
C. Drought resistance D. Enhancing selflife
4 The maximum number of existing transgenic animals is of _____ 1
A. Fish B. Mice C. Cow D. Pig
5 The process of RNA interference has been used in the 1
development of plants resistant to _____
A. Insects B. Nematodes C. Fungi D. Viruses
6 The first ever human hormone produced by recombinant DNA 1
technology is _____
A. Progesterone B. Insulin C. Estrogen D. Progesterone
7 Bt cotton, the Bt toxin present in plant tissue as pro-toxin in 1
converted into active toxin due to _____
A. Acidic pH of the insect gut B. Alkaline pH of the insect gut
C. Presence of conversion factors in insect gut D. Action of gut
microorganisms
8 Cry-I endotoxins obtained from Bacillus thuringiensis are 1
effective against ___
A. Nematodes B. Flies C. Mosquitoes D. Boll worms

9 Which of the following is not used as a biopesticide? 1

A. Xanthomonascampestris B. Bacillus thuringiensis1

C. Trichoderma harzianum D. Nuclear Polyhedrosis V1irus

10 Transgenic food crop which may help in solving the 1

problem of night blindness in developing countries is
_______

A. Golden Rice B. FlavrSavr tomatoes C. BT soybean D. Starlink

maize

Directions: In the following questions, a statement of assertion is 1

followed by a statement of reason. Mark the correct choice as: (a) If both
Assertion and Reason are true and Reason is the correct explanation of
Assertion. (b) If both Assertion and Reason are true but Reason is not the
correct explanation of Assertion. (c) If Assertion is true but Reason is
false. (d) If both Assertion and Reason are false.

11 Assertion: ‘Cry’ proteins are named so because they are crystal 1

proteins. Reason: In acidic environment of insect midgut ‘Cry’
proteins are solubilized and then release toxic core fragments
 after proteolytic action.

Ans-----------------------------------------------

12 Assertion: Cry gene expressing crop is resistant to a group of 1

insects. Reason: Cry proteins produced from Bacillus
thuringiensis are toxic to larvae of certain insects.

13 Assertion : Transgenic plant is a product of plant tissue culture. 1

Reason : An organism that contains and expresses a transgenic
organism.

14 Assertion : A crop expressing a cry gene is usually resistant to a 1

group of insects. Reason : Cry proteins produced from Bacillus
thuringiensis is toxic to larvae of certain insects.

15 Assertion :FlavrSavr, a transgenic tomato which remains fresh 1

and retains their flavour for long time. Reason : Production of
polygalacturonase enzyme, which degrades pectin, is blocked in
FlavrSavr.

16. Write the two specific ‘cry’ genes that encode the proteins which control cotton boll
worms.

17. Mention the chemical change that proinsulin undergoes, to be able to act as mature
insulin

18. What are cry genes? In which organisms are they present?

19. Suggest any two possible treatments that can be given to patient exhibiting
adenosine deaminase deficiency

20. State the role of C-peptide in human insulin