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    E.Vishnu Arjun 2009310027 Apparel Tech

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    Vishnu Arjun
    The document discusses the functions of the kidney and artificial kidneys. It describes how kidneys filter waste from the blood, regulate salt and water balance, and maintain homeostasis. It also explains that artificial kidneys consist of a filtration zone and excretion zone, and use dialysis membranes to separate toxic waste from the blood similarly to natural kidneys. The document provides details on the manufacturing process and testing of artificial kidney membranes and their role in replacing kidney functions for patients with renal failure.

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    E.Vishnu Arjun 2009310027 Apparel Tech

    Uploaded by

    Vishnu Arjun
    109 views22 pages
    The document discusses the functions of the kidney and artificial kidneys. It describes how kidneys filter waste from the blood, regulate salt and water balance, and maintain homeostasis. It also explains that artificial kidneys consist of a filtration zone and excretion zone, and use dialysis membranes to separate toxic waste from the blood similarly to natural kidneys. The document provides details on the manufacturing process and testing of artificial kidney membranes and their role in replacing kidney functions for patients with renal failure.

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    need-material characteristics-parts- working method- testing method

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    Artificial-Kidney.pptx

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    The document discusses the functions of the kidney and artificial kidneys. It describes how kidneys filter waste from the blood, regulate salt and water balance, and maintain homeostasis. It also explains that artificial kidneys consist of a filtration zone and excretion zone, and use dialysis membranes to separate toxic waste from the blood similarly to natural kidneys. The document provides details on the manufacturing process and testing of artificial kidney membranes and their role in replacing kidney functions for patients with renal failure.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    109 views22 pages

    E.Vishnu Arjun 2009310027 Apparel Tech

    Uploaded by

    Vishnu Arjun
    The document discusses the functions of the kidney and artificial kidneys. It describes how kidneys filter waste from the blood, regulate salt and water balance, and maintain homeostasis. It also explains that artificial kidneys consist of a filtration zone and excretion zone, and use dialysis membranes to separate toxic waste from the blood similarly to natural kidneys. The document provides details on the manufacturing process and testing of artificial kidney membranes and their role in replacing kidney functions for patients with renal failure.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    of 22

    E.VISHNU ARJUN 2009310027 APPAREL TECH.

    FUNCTION OF KIDNEY Blood filtration for removal of waste.


    Nephrons

    remove toxin and ultra filtration occurs through glomerular capillaries. homeostasis

    Maintain

    Maintain salt and water balance Regulate blood cells Regulate drug level

    Renal failure Chronic kidney disease

    Non toxic Non allergenic Bio compatible Sterlizable Strength Durability

    Dialysis can not maintain blood pressure. Dialysis can not maintain pH

    Leucocyte count in blood decrease.


    Dialysis may cause joint problem.

    Artificial kidney consists of two parts Filtration zone Excretion zone

    Dialysis membranes are stacked together. These are dense , defined shape and filter with bodys own blood pressure. Separate toxic waste from blood.

    In this zone , a kidney cell is coated on membrane to


    reabsorb water , sugar and salt.
    The waste goes to urinary bladder.

    The dialysis membrane are made up of viscose polysulphone, cuprophan and cuproammonium fibers.

    10

    Moderate mechanical strength Bio compatible

    Non toxic
    Selective absorption

    11

    Ultra thin Excellent ultra filtration

    Good mechanical strength

    12

    Selective removal of urea , ceretinine. Retain nutritive molecules such as vitamin B 12

    13

    The manufacturing of artificial kidney involves two steps : Batch fabrication process Physical deposition

    14

    Surface membrane = 0.8 2.0 m Membrane thickness = 15 micron

    Inner diameter = 180 micron


    Outer diameter = 200 300 micron

    15

    Blood flows into fiber and dialysate flows from fiber. Walls of fiber acts as dialyzer.

    16

    Blood flow rate greatly affects clearance of a small particles such as urea. Ultra filtration mainly removal of large solutes such as inulin. Solutes pass from high concentrated area to less concentrated area. The solute diffusive flux depends on concentration gradient, membrane thickness, diffusivity coefficient.

    17

    The convective flux depends on ultra filtration rate , concentration of plasma and solute sieving coefficient. Membrane surface area determines maximum clearance for given blood flow rate.

    18

    There are 2 ways to test performance of artificial kidney Sieve co efficiency test Renal clearance test Sieve coefficient test It is the ratio of renal clearance to ultra filtration rate.

    19

    The volume of plasma from which substance removed is completely removed by kidney in given amount of time. It is function of glomerular capillaries. It gives the amount of blood cleaned in a unit time.

    20

    Mass transfer coefficient Dialysate flow Solute sieving coefficient temperature

    21

    The artificial kidney is of great benefit for treatment of kidney patients. It has a healthy room in research sector.

    22

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